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Modern Biooxidation by Rolf D. Schmid,Vlada Urlacher Pdf
Filling a gap in the literature, leading expert editors and top international authors present the field of biooxidation from an academic and industrial point of view, taking many examples from modern pharmaceutical research. Topics range from the application of different monooxygenases to applications in the pharmaceutical industry, making this volume of high interest not only for those working in biotechnology but also for organic synthetic chemists, among others.
Redox Biocatalysis by Daniela Gamenara,Gustavo Seoane,Patricia Saenz Méndez,Pablo Domínguez de María Pdf
Paves the way for new industrial applications using redox biocatalysis Increasingly, researchers rely on the use of enzymes to perform redox processes as they search for novel industrial synthetic routes. In order to support and advance their investigations, this book provides a comprehensive and current overview of the use of redox enzymes and enzyme-mediated oxidative processes, with an emphasis on the role of redox enzymes in chemical transformations. The authors examine the full range of topics in the field, from basic principles to new and emerging research and applications. Moreover, they explore everything from laboratory-scale procedures to industrial manufacturing. Redox Biocatalysis begins with a discussion of the biochemical features of redox enzymes as well as cofactors and cofactor regeneration methods. Next, the authors present a variety of topics and materials to the research and development of full-scale industrial applications, including: Biocatalytic applications of redox enzymes such as dehydrogenases, oxygenases, oxidases, and peroxidases Enzyme-mediated oxidative processes based on biocatalytic promiscuity All the steps from enzyme discovery to robust industrial processes, including directed evolution, high-throughput screening, and medium engineering Case studies tracing the development of industrial applications using biocatalytic redox reactions Each chapter ends with concluding remarks, underscoring the key scientific principles and processes. Extensive references serve as a gateway to the growing body of research in the field. Researchers in both academia and industry will find this book an indispensable reference for redox biotransformations, guiding them from underlying core principles to new discoveries and emerging industrial applications.
Modern Oxidation Methods by Jan-Erling Bäckvall Pdf
While rust is an unwanted oxidation reaction, there are also many other useful oxidation reactions that are extremely important and number among the most commonly used reactions in the chemical industry. This completely revised, updated second edition now includes additional sections on industrial oxidation and biochemical oxidation. Edited by one of the world leaders in the field, high-quality contributions cover every important aspect from classical to green chemistry methods: - Recent Developments in Metal-catalyzed Dihydroxylation of Alkenes - Transition Metal-Catalyzed Epoxidation of Alkenes - Organocatalytic Oxidation. Ketone-Catalyzed Asymmetric Epoxidation of Alkenes and Synthetic Applications - Catalytic Oxidations with Hydrogen Peroxide in Fluorinated Alcohol Solvents - Modern Oxidation of Alcohols using Environmentally Benign Oxidants - Aerobic Oxidations and Related Reactions Catalyzed by N-Hydro xyphthalimide - Ruthenium-Catalyzed Oxidation for Organic Synthesis - Selective Oxidation of Amines and Sulfides - Liquid Phase Oxidation Reactions Catalyzed by Polyoxometalates - Oxidation of Carbonyl Compounds - Manganese-Catalyzed Oxidation with Hydrogen Peroxide - Biooxidation with Cytochrome P450 Monooxygenases By providing an overview of this vast topic, the book represents an unparalleled aid for organic, catalytic and biochemists working in the field.
Sustainable Solutions for Modern Economies by Rainer Hofer Pdf
Limited supplies of fossil fuels and concerns about global warming have created a strong desire to solve the resource issue in the age "beyond petroleum". This reference book, from the "Green Chemistry Series", contains the essential areas of green chemistry and sustainability in modern economies. It is the first book to outline the contribution of chemistry, and of renewable chemical or biological resources, to the sustainability concept and to the potential resolution of the world's energy problems. It describes the current status of technical research, and industrial application, as well as the potential of biomass as a renewable resource for energy generation in power stations, as alternative fuels, and for various uses in chemistry. It outlines the historical routes of the sustainability concept and specifies sustainability in metrics, facts and figures. The book is written by European experts from academia, industry and investment banking who are world leaders in research and technology regarding sustainability, alternative energies and renewable resources. The sustainability aspects covered include: * consumer behaviour and demands, lifestyles and mega trends, and their impact on innovation in the industry * consumer industry requirements and their impact on suppliers * emerging paradigm changes in raw material demand, availability, sourcing, and logistics * the contribution of the industry to restore the life support systems of the Earth * socially responsible banking and investment * sustainability metrics The book highlights the potential of the different forms of renewable raw materials including: * natural fats and oils * plant-based biologically active ingredients * industrial starch * sucrose * natural rubber * wood * natural fibres It also covers the actual status of biomass usage for green energy generation, green transportation, green chemistry and sustainable nutrition and consumer goods, and it depicts the potentials of green solvents and white biotechnology for modern synthesis and manufacturing technologies. The book is aimed at technical and marketing people in industry, universities and institutions as well as readers in administrations and NGOs. The book will also be of value to the worldwide public interested in sustainability issues and strategies as well as others interested in the practical means that are being used to reduce the environmental impact of chemical processes and products, to further eco-efficiency, and to advance the utilization of renewable resources.
Handbook of Green Chemistry by Paul T. Anastas Pdf
Edited by the inventor of the 12 principles of Green Chemistry, Paul Anastas, the complete 12-volumes of Handbook of Green Chemistry will provide a one-stop resource covering green catalysis, green solvents, green products and green processes. Handbook of Green Chemistry covers highly topical areas in green chemistry such as feedstocks, green chemical engineering, green catalysis (homogeneous, heterogeneous and biocatalysis), separation techniques and solvents like supercritical fluids, ionic liquids and reactions in water. It covers the big environmental and product design issues faced by chemists such as how to make nanoscience greener, design safer, sustainable and less toxic chemicals and make chemical synthesis a greener and more sustainable process. In the final 3 volumes, Handbook of Green Chemistry will cover green products, the chemical engineering behind their processing and what makes a green product, vital in now this is key selling point for industry. Handbook of Green Chemistry publishes in four sets of three volumes. The first three sets are available to purchase now: Handbook of Green Chemistry: Green Catalysis Paul T. Anastas (Series Editor), Robert H. Crabtree (Editor) ISBN: 978-3-527-31577-2 Hardcover | 1082 pages | January 2009 Handbook of Green Chemistry: Green Solvents Paul T. Anastas (Series Editor), Walter Leitner (Editor), Philip G. Jessop (Editor), Chao-Jun Li (Editor), Peter Wasserscheid (Editor), Annegret Stark (Editor) ISBN: 978-3-527-31574-1 Hardcover | 1412 pages | April 2010 Handbook of Green Chemistry: Green Processes Paul T. Anastas (Series Editor), Chao-Jun Li (Volume Editor) Hardcover | 1300 pages | April 2012 ISBN: 978-3-527-31576-5 The remaining set, Handbook of Green Chemistry: Green Products , will publish in May 2015. Introductory Offer! Order the full Hanbook of Green Chemistry, 12 Volume Set before 31st August 2015 and take advantage of the special introductory price as listed at the top of this webpage. Prices will revert to £1605.00/€1890.00/$2720.00 thereafter.
Practical Methods for Biocatalysis and Biotransformations 2 by John Whittall,Peter W. Sutton Pdf
Biocatalysts are increasingly used by chemists engaged in fine chemical synthesis within both industry and academia. Today, there exists a huge choice of high-tech enzymes and whole cell biocatalysts, which add enormously to the repertoire of synthetic possibilities. Practical Methods for Biocatalysis and Biotransformations 2 is a "how-to" guide that focuses on the practical applications of enzymes and strains of microorganisms that are readily obtained or derived from culture collections. The sources of starting materials and reagents, hints, tips and safety advice (where appropriate) are given to ensure, as far as possible, that the procedures are reproducible. Comparisons to alternative methodology are given and relevant references to the primary literature are cited. This second volume – which can be used on its own or in combination with the first volume - concentrates on new applications and new enzyme families reported since the first volume. Contents include: introduction to recent developments and future needs in biocatalysts and synthetic biology in industry reductive amination enoate reductases for reduction of electron deficient alkenes industrial carbonyl reduction regio- and stereo- selective hydroxylation oxidation of alcohols selective oxidation industrial hydrolases and related enzymes transferases for alkylation, glycosylation and phosphorylation C-C bond formation and decarboxylation halogenation/dehalogenation/heteroatom oxidation tandem and sequential multi-enzymatic syntheses Practical Methods for Biocatalysis and Biotransformations 2 is an essential collection of biocatalytic methods for chemical synthesis which will find a place on the bookshelves of synthetic organic chemists, pharmaceutical chemists, and process R&D chemists in industry and academia.
The shift towards being as environmentally-friendly as possible has resulted in the need for this important volume on the topic of biocatalysis. Edited by the father and pioneer of Green Chemistry, Professor Paul Anastas, and by the renowned chemist, Professor Robert Crabtree, this volume covers many different aspects, from industrial applications to the latest research straight from the laboratory. It explains the fundamentals and makes use of everyday examples to elucidate this vitally important field. An essential collection for anyone wishing to gain an understanding of the world of green chemistry, as well as for chemists, environmental agencies and chemical engineers.
Cytochrome P450 by Paul R. Ortiz de Montellano Pdf
This authoritative Fourth Edition summarizes the advances of the past decade concerning the structure, mechanism, and biochemistry of cytochrome P450 enzymes, with sufficient coverage of earlier work to make each chapter a comprehensive review of the field. Thirteen chapters are divided into two detailed volumes, the first covering the fundamentals of cytochrome P450 biochemistry, as well as the microbial, plant, and insect systems, and the second exclusively focusing on mammalian systems. Volume 1 begins with an exploration of the biophysics and mechanistic enzymology of cytochrome P450 enzymes, with a discussion of the structures of P450 enzymes and their electron donor partners, the mechanisms of oxygen activation and substrate oxidation, and the approaches and nature of cytochrome P450 inhibition. Two more chapters discuss the nature and roles of cytochrome P450 enzymes in microbes, plants and insects, and an eighth chapter is a survey of the potential utility of P450 enzymes in biotechnology. The first chapter of Volume 2 examines the roles of P450 enzymes in mammals, mainly humans. Four further chapters then deal with the genetic and hormonal regulation of P450 enzymes and their specific roles in the processing of sterols and lipids. Cytochrome P450: Structure, Mechanism, and Biochemistry is a key resource for scientists, professors, and students interested in fields as diverse as biochemistry, chemistry, biophysics, molecular biology, pharmacology and toxicology.
This book, written by leading international authorities in the field, covers all the basic and applied aspects of acetic acid bacteria. It describes the importance of acetic acid bacteria in food industry by giving information on the microbiological properties of fermented foods as well as production procedures. Special attention is given to vinegar and cocoa, which are the most familiar and extensively used industrial applications of acetic acid bacteria. This book is an essential reference to all scientists, technologists, engineers, students and all those working in the field of food science and technology.
Acetic Acid Bacteria by Kazunobu Matsushita,Hirohide Toyama,Naoto Tonouchi,Akiko Okamoto-Kainuma Pdf
This book provides all facets of acetic acid bacteria (AAB) and offers the future targets and directions of AAB research. It summarizes the distinctive physiological properties of AAB and the recent progress on AAB study, especially in the following five areas: 1) Molecular phylogeny and genome study of AAB; 2) Ecological features of AAB: interaction with plants, natural fermentation systems, and insects; 3) Physiological features and living strategies of AAB, including rapid oxidation ability, acid resistance, biofilm formation, and genetic instability; 4) Molecular mechanisms of several oxidative fermentations such as acetate fermentation, sorbose fermentation, and ketogluconate fermentation; 5) Recent biotechnological aspects of AAB: biocatalysts, biosensors, biocellulose, and other useful polysaccharides. AAB research has a long history since the discovery of AAB by Louis Pasteur and the identification of AAB by Martinus Beijerinck in the nineteenth century. In the twentieth century, basic research on the taxonomic study of AAB and on biochemical study for the unique oxidative reactions of AAB had progressed as well as the industrial application of AAB not only in vinegar fermentation but also in the bioconversion process for useful chemical or pharmaceutical products. Entering the twenty-first century, AAB research has expanded more, and further progress is expected to be seen in all fields of AAB: classification and ecology, physiology and biochemistry, genetics, and biotechnology of vinegar fermentation and other oxidative fermentations. Far-reaching development in the last decade makes these bacteria more valuable for various industrial uses. Readers can obtain useful and comprehensive information which is exciting in aspects of basic science and provides hints for the better application of these bacteria to various kinds of practical production scenarios as well.
Enzyme Catalysis in Organic Synthesis, 3 Volume Set by Karlheinz Drauz,Harald Gröger,Oliver May Pdf
This comprehensive three-volume set is the standard reference in the field of organic synthesis, catalysis and biocatalysis. Edited by a highly experienced and highly knowledgeable team with a tremendous amount of experience in this field and its applications, this edition retains the successful concept of past editions, while the contents are very much focused on new developments in the field. All the techniques described are directly transferable from the lab to the industrial scale, making for a very application-oriented approach. A must for all chemists and biotechnologists.
Author : Gonzalo de Gonzalo,Pablo Domínguez de María Publisher : Royal Society of Chemistry Page : 532 pages File Size : 51,8 Mb Release : 2017-11-02 Category : Science ISBN : 9781782626190
Biocatalysis by Gonzalo de Gonzalo,Pablo Domínguez de María Pdf
Implementing biocatalytic strategies in an industrial setting is a challenging task, especially when commercial scale necessitates a balance between industrial need and economic viability. With invited contributions from a wide range of chemical and pharmaceutical companies, this book bridges the gap between academia and industry. Contributors discuss current processes, types of biocatalysts and improvements, industrial motivation and the key aspects needed for economic success. Focussing on industry related issues, this book will be a useful tool for future research by both practitioners and academics.
Biocatalysis for Green Chemistry and Chemical Process Development by Junhua (Alex) Tao,Romas Joseph Kazlauskas Pdf
This book describes recent progress in enzyme-driven green syntheses of industrially important molecules. The first three introductory chapters overview recent technological advances in enzymes and cell-based transformations, and green chemistry metrics for synthetic efficiency. The remaining chapters are directed to case studies in biotechnological production of pharmaceuticals (small molecules, natural products and biologics), flavors, fragrance and cosmetics, fine chemicals, value-added chemicals from glucose and biomass, and polymeric materials. The book is aimed to facilitate the industrial applications of this powerful and emerging green technology, and catalyze the advancement of the technology itself.
Organic Chemistry by Pierre Vogel,Kendall N. Houk Pdf
Provides the background, tools, and models required to understand organic synthesis and plan chemical reactions more efficiently Knowledge of physical chemistry is essential for achieving successful chemical reactions in organic chemistry. Chemists must be competent in a range of areas to understand organic synthesis. Organic Chemistry provides the methods, models, and tools necessary to fully comprehend organic reactions. Written by two internationally recognized experts in the field, this much-needed textbook fills a gap in current literature on physical organic chemistry. Rigorous yet straightforward chapters first examine chemical equilibria, thermodynamics, reaction rates and mechanisms, and molecular orbital theory, providing readers with a strong foundation in physical organic chemistry. Subsequent chapters demonstrate various reactions involving organic, organometallic, and biochemical reactants and catalysts. Throughout the text, numerous questions and exercises, over 800 in total, help readers strengthen their comprehension of the subject and highlight key points of learning. The companion Organic Chemistry Workbook contains complete references and answers to every question in this text. A much-needed resource for students and working chemists alike, this text: -Presents models that establish if a reaction is possible, estimate how long it will take, and determine its properties -Describes reactions with broad practical value in synthesis and biology, such as C-C-coupling reactions, pericyclic reactions, and catalytic reactions -Enables readers to plan chemical reactions more efficiently -Features clear illustrations, figures, and tables -With a Foreword by Nobel Prize Laureate Robert H. Grubbs Organic Chemistry: Theory, Reactivity, and Mechanisms in Modern Synthesis is an ideal textbook for students and instructors of chemistry, and a valuable work of reference for organic chemists, physical chemists, and chemical engineers.