Molecular Technologies For Detection Of Chemical And Biological Agents

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Molecular Technologies for Detection of Chemical and Biological Agents

Joseph H. Banoub,Richard M. Caprioli
Molecular Technologies for Detection of Chemical and Biological Agents Book PDF

Author : Joseph H. Banoub,Richard M. Caprioli
Publisher : Springer
Page : 306 pages
File Size : 53,8 Mb
Release : 2017-07-05
Category : Science
ISBN : 9789402411133

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Molecular Technologies for Detection of Chemical and Biological Agents by Joseph H. Banoub,Richard M. Caprioli Pdf

This book describes the latest molecular insights needed to understand the chemical and biological (CB) agents and their associated biotechnologies. Its primary focus is to present and discuss molecular technologies such as mass spectrometry, chemical and biological sensors, chromatographic and electrophoretic separation, and comparisons of spectroscopic, immunological and molecular analyses of chemicals used for the detection of chemical and biological agents and to prevent terrorism. This NATO-ASI book also contributes to the critical assessment of existing knowledge on new and important detection technologies. It helps to identify directions for future research and to promote closer working relationships between scientists from different professional fields.

Toxic Chemical and Biological Agents

Giovanni Sindona,Joseph H. Banoub,Maria Luisa Di Gioia
Toxic Chemical and Biological Agents Book PDF

Author : Giovanni Sindona,Joseph H. Banoub,Maria Luisa Di Gioia
Publisher : Springer Nature
Page : 282 pages
File Size : 42,9 Mb
Release : 2020-10-19
Category : Science
ISBN : 9789402420418

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Toxic Chemical and Biological Agents by Giovanni Sindona,Joseph H. Banoub,Maria Luisa Di Gioia Pdf

This book critically assesses the current state of knowledge on new and important detection technologies, e.g. mass spectrometry, tandem mass spectrometry, biosensor detection and tissue imaging, in connection with toxic chemical and biological agents. In general, the main topics discussed concern the risks and consequences of chemical and biological agents for human health in general, with special emphasis on all biochemical and metabolic pathways including the reproductive system. The exposome, genetic risks and the environment, various health hazard agents, risk assessment, environmental assessment and preparedness, and analysis of sub-lethal effects at the molecular level are also discussed. In closing, the book provides comprehensive information on the diagnosis of exposure, and on health concerns related to toxic chemical and biological agents.

Detection of Biological Agents for the Prevention of Bioterrorism

Joseph Banoub
Detection of Biological Agents for the Prevention of Bioterrorism Book PDF

Author : Joseph Banoub
Publisher : Springer Science & Business Media
Page : 360 pages
File Size : 47,6 Mb
Release : 2010-11-05
Category : Science
ISBN : 9789048198795

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Detection of Biological Agents for the Prevention of Bioterrorism by Joseph Banoub Pdf

The threat of biological and chemical terrorism has driven the demand for timely techniques that can quickly detect the agent or agents used in an attack. The detection and/or prevention of these potential security threats provide significant scientific and technical challenges due to the combination of possible agents and modes of delivery available. This book will present a thorough look at the importance and technological challenges of mass spectrometry (MS) for the detection & identification of biological and chemical threats. This new contribution’s general aims are to draw the attention of recognized practitioners, experts and graduate students trying to grasp the latest MS developments in the cutting-edge fields of MS-biodefense technologies for the rapid/early/specific sensitive threat detection of pathogens, viruses, explosives, mycotoxins, chemical agents, and biological markers of xenobiotic chemicals.

Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism

Joseph Banoub
Detection of Chemical Biological Radiological and Nuclear Agents for the Prevention of Terrorism Book PDF

Author : Joseph Banoub
Publisher : Springer
Page : 291 pages
File Size : 43,7 Mb
Release : 2014-11-03
Category : Science
ISBN : 9789401792387

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Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism by Joseph Banoub Pdf

This NATO-ASI installment is designed to provide an advanced overview for doctoral and post-doctoral candidates of the state-of-the-art technologies for bio-detection. The main objective of the work aims at providing readers with the latest developments necessary to successfully understand the CBRN Agents and their associated biotechnologies. The core methods focused on are mass spectrometry (including chromatographic and electrophoretic separation) and comparisons to spectroscopic, immunological and molecular analysis of chemical, biological and nuclear agents.

Chemical and Biological Terrorism

Committee on R&D Needs for Improving Civilian Medical Response to Chemical and Biological Terrorism Incidents,Institute of Medicine
Chemical and Biological Terrorism Book PDF

Author : Committee on R&D Needs for Improving Civilian Medical Response to Chemical and Biological Terrorism Incidents,Institute of Medicine
Publisher : National Academies Press
Page : 303 pages
File Size : 41,8 Mb
Release : 1999-02-26
Category : History
ISBN : 9780309523141

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Chemical and Biological Terrorism by Committee on R&D Needs for Improving Civilian Medical Response to Chemical and Biological Terrorism Incidents,Institute of Medicine Pdf

The threat of domestic terrorism today looms larger than ever. Bombings at the World Trade Center and Oklahoma City's Federal Building, as well as nerve gas attacks in Japan, have made it tragically obvious that American civilians must be ready for terrorist attacks. What do we need to know to help emergency and medical personnel prepare for these attacks? Chemical and Biological Terrorism identifies the R&D efforts needed to implement recommendations in key areas: pre-incident intelligence, detection and identification of chemical and biological agents, protective clothing and equipment, early recognition that a population has been covertly exposed to a pathogen, mass casualty decontamination and triage, use of vaccines and pharmaceuticals, and the psychological effects of terror. Specific objectives for computer software development are also identified. The book addresses the differences between a biological and chemical attack, the distinct challenges to the military and civilian medical communities, and other broader issues. This book will be of critical interest to anyone involved in civilian preparedness for terrorist attack: planners, administrators, responders, medical professionals, public health and emergency personnel, and technology designers and engineers.

Bioaerosol Detection Technologies

Per Jonsson,Göran Olofsson,Torbjörn Tjärnhage
Bioaerosol Detection Technologies Book PDF

Author : Per Jonsson,Göran Olofsson,Torbjörn Tjärnhage
Publisher : Springer
Page : 330 pages
File Size : 49,5 Mb
Release : 2014-07-31
Category : Science
ISBN : 9781441955821

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Bioaerosol Detection Technologies by Per Jonsson,Göran Olofsson,Torbjörn Tjärnhage Pdf

This book is intended to give technological background and practical examples, but also to give general insight into the on-going technology development in the area of biodetection. The content is therefore suitable for an array of stakeholders (decision makers, purchasing officers, etc.) and end-users of biodetection equipment within the areas of health, environment, safety and security, and military preparation. The book is divided into three sections. The first section discusses the fundamental physical and biological properties of bioaerosol's. The second section goes into more detail and discusses in-depth the most commonly used detection principles. The third section of the book is devoted to technologies that have been used in standoff applications. The last section of the book gives an overview of trends in bioaerosol detection. The reader of this book will gain knowledge about the different biodetection technologies and thus better judge their capabilities in relation to desired applications.

Nanotechnology for Chemical and Biological Defense

Margaret Kosal
Nanotechnology for Chemical and Biological Defense Book PDF

Author : Margaret Kosal
Publisher : Springer Science & Business Media
Page : 163 pages
File Size : 47,6 Mb
Release : 2009-06-11
Category : Technology & Engineering
ISBN : 9781441900623

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Nanotechnology for Chemical and Biological Defense by Margaret Kosal Pdf

New and unpredicted technologies are emerging at an unprecedented pace around the world. Communication of those new discoveries is occurring faster than ever, meaning that the unique ownership of a piece of new technology is no longer a sufficient position, if not impossible. In today’s world, recognition of the potential applications of a technology and a sense of purpose in exploiting it are far more important than simply having access to it. Technological surprise has and will continue to take many forms. A plethora of new technologies are under development for peaceful means but may have un- tended security consequences and will certainly require innovative counterme- ures. A relevant example is the tremendous development in biotechnology that has occurred since the advent of recombinant DNA and tissue culture-based processes in the 1970s. If US government agencies and the defense and academic commu- ties had more clearly recognized the potential for biotechnology to affect fun- mental security and warfighting doctrines 20 years ago, the situation today could be very different. Defense against chemical and biological weapons – from both states and nonstate actors – currently presents a threat that is difficult to predict and for which traditional solutions are increasingly less effective. Nanotechnology has emerged as a well-funded discipline that, like biote- nology, carries the potential for groundbreaking applications and the potential for unpredictable harm. The world is likely 20 years away from the full impact of the nanotechnology on defensive capabilities.

Commercial and Pre-Commercial Cell Detection Technologies for Defence Against Bioterror

L.M. Lechuga,F.P. Milanovich,P. Skládal
Commercial and Pre Commercial Cell Detection Technologies for Defence Against Bioterror Book PDF

Author : L.M. Lechuga,F.P. Milanovich,P. Skládal
Publisher : IOS Press
Page : 180 pages
File Size : 54,6 Mb
Release : 2008-07-03
Category : Political Science
ISBN : 9781607503286

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Commercial and Pre-Commercial Cell Detection Technologies for Defence Against Bioterror by L.M. Lechuga,F.P. Milanovich,P. Skládal Pdf

As a response to the rapidly emerging threat of bioterrorism, the objectives of this volume on Commercial and Pre-Commercial Cell Detection Technologies for Defence against Bioterror are to exchange information on commercially available technologies and equipment for defense against bioterrorism; to further the development of new biosensor system prototypes into a commercially available apparatus and to explore human factors in BWA biosensors. The new commercial and pre-commercial technologies that are currently emerging in the world are presented and explained. Furthermore, there is a discussion about the interaction of modern detection systems with society and a trial for improvement of the relation between the scientific community and commercial entities. There are four major areas highlighted: the first is a presentation of the most advanced biosensors and biodetection system which can be found in the market or are quite close to commercialization. Systems as the BIOHAWKTM, SASS 2000, RAPTOR, Bionas® 2500, OWLS, or a portable SPR are presented in this section. The second issue is a presentation of the advances in the research of biodetection devices as DNA and protein microchips, micro and nanophotonic sensors, CMOS microsensor chips, electrochemical arrays, physical platforms, electro optical detection, mass detection, etc. Then, there is a description of the latest developments in the employment of bioreceptor layers for the selective detection of BWA, as protein signatures, molecular imprinted polymers, membrane engineering (MIME), cell signatures, monoclonal antibodies, synthetic antibodies and lytic phages, among others. The last part is the discussion of the human factor: societal issues related to sensor development and employment for BWA detection.

Nano and Microsensors for Chemical and Biological Terrorism Surveillance

Jeffrey B.-H. Tok
Nano and Microsensors for Chemical and Biological Terrorism Surveillance Book PDF

Author : Jeffrey B.-H. Tok
Publisher : Royal Society of Chemistry
Page : 222 pages
File Size : 51,7 Mb
Release : 2008
Category : Political Science
ISBN : 9780854041404

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Nano and Microsensors for Chemical and Biological Terrorism Surveillance by Jeffrey B.-H. Tok Pdf

"This unique book is the only current publication that provides readers with a brief, yet concise, collection of the latest advances in chemical and biological agent detection and/or their surveillance. Nano and Microsensors for Chemical and Biological Terrorism Surveillance compiles and gives in-depth detail on several detection schemes so that the reader is provided with a general sense of these micro and nanoscale sensing systems and platforms." --Book Jacket.

Defense against Bioterror: Detection Technologies, Implementation Strategies and Commercial Opportunities

Dennis Morrison
Defense against Bioterror Detection Technologies Implementation Strategies and Commercial Opportunities Book PDF

Author : Dennis Morrison
Publisher : Springer Science & Business Media
Page : 350 pages
File Size : 46,7 Mb
Release : 2005-12-13
Category : Medical
ISBN : 1402033869

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Defense against Bioterror: Detection Technologies, Implementation Strategies and Commercial Opportunities by Dennis Morrison Pdf

This is a critical assessment of breakthrough biosensor technologies that will allow for the rapid identification of biological threat agents in the environment and human population. The book provides a comprehensive overview of the current state of biological weapons threat, and reviews biosensor technologies including detection platforms, networked alarm-type biodetector systems, implementation strategies, electro-optical and electrochemical biosensors.

Handbook on Biological Warfare Preparedness

S.J.S. Flora,Vidhu Pachauri
Handbook on Biological Warfare Preparedness Book PDF

Author : S.J.S. Flora,Vidhu Pachauri
Publisher : Academic Press
Page : 306 pages
File Size : 51,9 Mb
Release : 2019-10-05
Category : Medical
ISBN : 9780128120552

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Handbook on Biological Warfare Preparedness by S.J.S. Flora,Vidhu Pachauri Pdf

Handbook on Biological Warfare Preparedness provides detailed information on biological warfare agents and their mode of transmission and spread. In addition, it explains methods of detection and medical countermeasures, including vaccine and post-exposure therapeutics, with specific sections detailing diseases, their transmission, clinical signs and symptoms, diagnosis, treatment, vaccines, prevention and management. This book is useful reading for researchers and advanced students in toxicology, but it will also prove helpful for medical students, civil administration, medical doctors, first responders and security forces. As the highly unpredictable nature of any event involving biological warfare agents has given rise to the need for the rapid development of accurate detection systems, this book is a timely resource on the topic. Introduces different bacterial and viral agents, including Ebola and other emerging threats and toxins Discusses medical countermeasures, including vaccines and post-exposure therapeutics Includes a comprehensive review of current methods of detection

Test and Evaluation of Biological Standoff Detection Systems

National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Test and Evaluation of Biological Standoff Detection Systems
Test and Evaluation of Biological Standoff Detection Systems Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Test and Evaluation of Biological Standoff Detection Systems
Publisher : National Academies Press
Page : 42 pages
File Size : 45,8 Mb
Release : 2008-08-29
Category : Political Science
ISBN : 9780309114431

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Test and Evaluation of Biological Standoff Detection Systems by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Test and Evaluation of Biological Standoff Detection Systems Pdf

A biological warfare agent (BWA) is a microorganism, or a toxin derived from a living organism, that causes disease in humans, plants, or animals or that causes the deterioration of material. The effectiveness of a BWA is greatly reduced if the attack is detected in time for the target population to take appropriate defensive measures. Therefore, the ability to detect a BWA, in particular to detect it before the target population is exposed, will be a valuable asset to defense against biological attacks. The ideal detection system will have quick response and be able to detect a threat plume at a distance from the target population. The development of reliable biological standoff detection systems, therefore, is a key goal. However, testing biological standoff detection systems is difficult because open-air field tests with BWAs are not permitted under international conventions and because the wide variety of environments in which detectors might be used may affect their performance. This book explores the question of how to determine whether or not a biological standoff detection system fulfills its mission reliably if we cannot conduct open-air field tests with live BWAs.

Beyond the Molecular Frontier

National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Challenges for the Chemical Sciences in the 21st Century
Beyond the Molecular Frontier Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Challenges for the Chemical Sciences in the 21st Century
Publisher : National Academies Press
Page : 238 pages
File Size : 51,8 Mb
Release : 2003-03-19
Category : Science
ISBN : 9780309168397

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Beyond the Molecular Frontier by National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Challenges for the Chemical Sciences in the 21st Century Pdf

Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.

Defending the U.S. Air Transportation System Against Chemical and Biological Threats

National Research Council,Division on Engineering and Physical Sciences,National Materials Advisory Board,Committee on Assessment of Security Technologies for Transportation
Defending the U S Air Transportation System Against Chemical and Biological Threats Book PDF

Author : National Research Council,Division on Engineering and Physical Sciences,National Materials Advisory Board,Committee on Assessment of Security Technologies for Transportation
Publisher : National Academies Press
Page : 46 pages
File Size : 54,5 Mb
Release : 2006-01-10
Category : Medical
ISBN : 9780309181150

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Defending the U.S. Air Transportation System Against Chemical and Biological Threats by National Research Council,Division on Engineering and Physical Sciences,National Materials Advisory Board,Committee on Assessment of Security Technologies for Transportation Pdf

Historically, most terrorist attacks on civilian targets have involved the use of firearms or explosives, and current defensive strategies are aimed at preventing attacks perpetrated by such means. However, the use of the nerve agent sarin in 1995 to attack the Tokyo subway system, the use of the U.S. mail in 2001 to distribute letters containing anthrax spores, and the discovery in 2004 of the biological toxin ricin in U.S. Senate Office Buildings in Washington, D.C., demonstrate that chemical and biological agents have been added to terrorists' arsenals. Attacks involving chemical/biological agents are of great concern, not only because of the potential for mass casualties but also because there is no strategy or technology fielded today that can respond adequately to this threat. As the United States and other countries reassess the security measures they have in place to prevent or defend against such attacks, the risks to the air transportation system as a primary target become clear. Defending the U.S. Air Transportation System Against Chemical and Biological Threats is an exploration of defensive strategies that could be used to protect air transportation spaces (specifically, airport terminals and aircraft) against attack with chemical or biological agents and makes recommendations with respect to the role of TSA in implementing these strategies.

Biodefense in the Age of Synthetic Biology

National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology
Biodefense in the Age of Synthetic Biology Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology
Publisher : National Academies Press
Page : 189 pages
File Size : 53,7 Mb
Release : 2019-01-05
Category : Technology & Engineering
ISBN : 9780309465182

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Biodefense in the Age of Synthetic Biology by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology Pdf

Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.