Myeloid Malignancies

Author : The American Cancer Society
Publisher : John Wiley & Sons
Page : 727 pages
File Size : 41,8 Mb
Release : 2018-05-01
Category : Medical
ISBN : 9781118517642

Get Book

The American Cancer Society's Oncology in Practice by The American Cancer Society Pdf

Developed by the American Cancer Society this new textbook designed for a wide range of learners and practitioners comprehensively addresses all aspects of clinical management for cancer taking a balanced, authoritative and, -where possible- evidence-based stance and may be used in conjunction with the book, The American Cancer Society's Principles of Oncology: Prevention to Survivorship. Edited by leading clinicians in the field and a stellar contributor list from the US and Europe, this book is written in an easy to understand style by multidisciplinary teams of medical oncologists, radiation oncologists and other specialists, reflecting day-to-day decision-making and clinical practice. Input from pathologists, surgeons, radiologists, and other specialists is included wherever relevant and comprehensive treatment guidelines are provided by expert contributors where there is no standard recognized treatment. This book is an ideal resource for anyone seeking a practical understanding of the field of oncology.

Author : Hillard M. Lazarus,Mary J. Laughlin
Publisher : Springer Science & Business Media
Page : 881 pages
File Size : 53,7 Mb
Release : 2010-03-02
Category : Medical
ISBN : 9781597454780

Get Book

Allogeneic Stem Cell Transplantation by Hillard M. Lazarus,Mary J. Laughlin Pdf

Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.

Author : Nicolaus Kröger,John Gribben,Christian Chabannon,Ibrahim Yakoub-Agha,Hermann Einsele
Publisher : Springer Nature
Page : 221 pages
File Size : 52,9 Mb
Release : 2022-02-07
Category : Medical
ISBN : 9783030943530

Get Book

The EBMT/EHA CAR-T Cell Handbook by Nicolaus Kröger,John Gribben,Christian Chabannon,Ibrahim Yakoub-Agha,Hermann Einsele Pdf

This first open access European CAR-T Handbook, co-promoted by the European Society for Blood and Marrow Transplantation (EBMT) and the European Hematology Association (EHA), covers several aspects of CAR-T cell treatments, including the underlying biology, indications, management of side-effects, access and manufacturing issues. This book, written by leading experts in the field to enhance readers’ knowledge and practice skills, provides an unparalleled overview of the CAR-T cell technology and its application in clinical care, to enhance readers’ knowledge and practice skills.

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 47,9 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

Get Book

Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Ann Mullally
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 54,6 Mb
Release : 2017-07-14
Category : Medical
ISBN : 9780323532365

Get Book

The Treatment of Myeloid Malignancies with Kinase Inhibitors, An Issue of Hematology/Oncology Clinics of North America, E-Book by Ann Mullally Pdf

This issue of Hematology/Oncology Clinics will focus on The Treatment of Myeloid Malignancies with Kinase Inhibitors. Articles will focus on: Targeting aberrant signaling in myeloid malignancies: promise versus reality; The development and use of imatinib for the treatment of chronic myelogenous leukemia; Mechanisms of resistance to ABL kinase inhibition in CML and the development of next generation ABL kinase inhibitors; Tyrosine kinase inhibitors in the treatment of systemic mastocytosis and hypereosinophilic syndrome; The development and use of JAK2 inhibitors for the treatment of myeloproliferative neoplasms (MPN); Mechanisms of resistance to JAK2 inhibitors in MPN; Kinase inhibitor screening in myeloid malignancies; and more!

Author : Chung-Che (Jeff) Chang,Robert S. Ohgami
Publisher : Springer
Page : 427 pages
File Size : 47,7 Mb
Release : 2017-09-25
Category : Medical
ISBN : 9783319621463

Get Book

Precision Molecular Pathology of Myeloid Neoplasms by Chung-Che (Jeff) Chang,Robert S. Ohgami Pdf

This volume provides a comprehensive, state-of-the art review of myeloid neoplasms. The book presents updated information on epidemiology, clinical presentation, morphologic findings, molecular genomic abnormalities, pathogenesis, and target therapies. The text helps to guide accurate diagnosis, the administration of appropriate ancillary molecular tests, patient management, and investigative efforts. The book also includes over 200 illustrations, photographs, and tables. Written by experts in the field, Precision Molecular Pathology of Myeloid Neoplasms serves as a valuable resource for pathologists, hematologists/oncologists, fellows, and researchers in understanding the molecular pathology of myeloid neoplasms.

Author : Bruno Fattizzo,Austin Kulasekararaj,Matteo Claudio Da Vià
Publisher : Frontiers Media SA
Page : 117 pages
File Size : 47,7 Mb
Release : 2022-07-07
Category : Medical
ISBN : 9782889765300

Get Book

Immunologic Mechanisms of Myeloid Neoplasms by Bruno Fattizzo,Austin Kulasekararaj,Matteo Claudio Da Vià Pdf

Author : Barbara J. Bain,Estella Matutes
Publisher : Clinical Pub
Page : 0 pages
File Size : 43,5 Mb
Release : 2010
Category : Blood
ISBN : 1846920558

Get Book

Myeloid Malignancies by Barbara J. Bain,Estella Matutes Pdf

Aimed at meeting the needs for haematologists and clinical chemists for a reference, this atlas offers a visual presentation of myeloproliferative neoplasms and myeloid leukaemia. It surveys individual disease, covering the clinical presentation, haematological and pathological features, immunophenotyping and cytogenetic and genetic abnormalities.

Author : David A. Sallman, MD,Ateefa Chaudhury, MD,Johnny Nguyen, MD,Ling Zhang, MD,Alan F. List, MD
Publisher : Springer Publishing Company
Page : 404 pages
File Size : 44,7 Mb
Release : 2016-11-28
Category : Medical
ISBN : 9781617052705

Get Book

Handbook of Hematologic Malignancies by David A. Sallman, MD,Ateefa Chaudhury, MD,Johnny Nguyen, MD,Ling Zhang, MD,Alan F. List, MD Pdf

Handbook of Hematologic Malignancies provides a unique, practical, and concise guide focused on the must-know points of diagnosis, prognosis, therapeutic management, and cutting edge clinical trial opportunities for each hematologic malignancy. With an ever-increasing growth of evidence and a significant expansion of available treatment options for patients with hematologic disease, remaining current and up-to-date can be extremely challenging for practicing clinicians. This comprehensive subspecialty handbook is designed and organized for the busy hematologist, hematologic oncologist, hematopathologist, and trainee in mind. Every chapter is richly illustrated with color figures and flow diagrams, and contains helpful tables on differential diagnosis, prognostic scoring systems and therapeutic options. A concise case-based review for testing pathologic diagnosis and clinical knowledge for each chapter is included for digital download online and in the e-book. Written by experienced clinicians at the world-renowned Moffitt Cancer Center in Tampa, Florida, as well as contributions from leading academicians throughout the country, this handbook is an essential resource for anyone diagnosing, treating, or managing patients with hematologic malignancy. KEY FEATURES: Contains clear prognostic and diagnostic tools (e.g., tables/flow diagrams/pathology images) with emphasis on key differential diagnoses and diagnostic dilemmas Easy to use treatment recommendations with bullet point format and key references. Discusses the future of patient management based on practice changing clinical trials Includes access to digitally downloadable case-based clinical scenarios and questions with high resolution pathology images linked to each individual chapter

Author : MiKaela M. Olsen,Laura J. Zitella
Publisher : Unknown
Page : 0 pages
File Size : 53,5 Mb
Release : 2013
Category : Hematopoietic system
ISBN : 1935864262

Get Book

Hematologic Malignancies in Adults by MiKaela M. Olsen,Laura J. Zitella Pdf

More than 180 years since Thomas Hodgkin identified the first hematologic malignancy, nurses are still learning the best ways to treat patients with these complex cancers. Hematologic Malignancies in Adults gives you comprehensive information on treatments, complications, and toxicity management for your everyday practice. The book focuses on the management of disease-related manifestations and treatment-related side effects and toxicities. You'll find details on forms of hematologic malignancies, including leukemia and lymphoma, Hodgkin lymphoma, mature T-cell and NK-cell neoplasms, and multiple myeloma. Also included is a chapter on vascular access and a listing of drugs used in the treatment of hematologic malignancies. The management of patients with myeloid and lymphoid neoplasms is unique, complex, and vital to ensuring successful outcomes and improved quality of life. This book gives you every tool you need to keep pace with the advances in medicine and science as you trea

Author : Harry Iland,Mark Hertzberg,Paula Marlton
Publisher : Springer Science & Business Media
Page : 308 pages
File Size : 48,7 Mb
Release : 2008-02-02
Category : Medical
ISBN : 9781597450171

Get Book

Myeloid Leukemia by Harry Iland,Mark Hertzberg,Paula Marlton Pdf

A panel of internationally recognized research scientists and clinical investigators brings together a diverse collection of readily reproducible methods for identifying and quantifying a large number of specific genetic abnormalities associated with the broad spectrum of myeloid malignancies. Highlights include techniques for the detection of BCR-ABL mutations and resistance to imatinib mesylate, detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia, classification of AML by DNA-oligonucleotide microarrays, and detection of the V617F JAK2 mutation in myeloproliferative disorders. In addition to gene rearrangments, other prognostically relevant molecular lesions such as FLT3 mutations and WT-1 overexpression are covered.

Author : Manorama Bhargava
Publisher : Springer Nature
Page : 246 pages
File Size : 50,9 Mb
Release : 2021-02-13
Category : Medical
ISBN : 9789813347991

Get Book

Hematologic Malignancies by Manorama Bhargava Pdf

This book is a compendium of case studies in hematologic malignancies such as acute leukemias, myelodysplastic and myeloproliferative neoplasms, chronic leukemias and multiple myeloma covering cytogenetics (karyotyping Fluorescence in sitn hybridization (FISH)) and molecular studies in detail. The first few chapters describe the methodology employed for karyotyping, FISH and Real Time PCR technology conducive to establishment of these labs if required. Each case study is described in detail by including the clinical history of the patient, findings of peripheral blood, bone marrow aspirate and bone biopsy morphological details. This is then followed by flowcytometric immunophenotyping, cytogenetic and molecular observations leading collectively to a final diagnosis, A discussion follows based on the relevance of this data in informing the prognosis, treatment response and survival in these patients. Additionally, this data serves as a key determinant for clinical decision making involving evidence based rational management of patients including targeted therapy. For better understanding, each case study is accompanied by black and white or colour images as appropriate. This book is a source of learning and a valuable read for clinical hematologists, hematopathologists, medical oncologists, residents, interns, DM Hematology students and DNB Hematology students as well.

Author : S.H. Faderl,H.M. Kantarjian
Publisher : Springer Science & Business Media
Page : 294 pages
File Size : 44,7 Mb
Release : 2007-11-21
Category : Medical
ISBN : 9783540723042

Get Book

Hematologic Malignancies: Acute Leukemias by S.H. Faderl,H.M. Kantarjian Pdf

Better therapy of acute leukemias depends ultimately on better understanding of the distinction between leukemic and normal progenitor cells. This hugely important new book describes the current knowledge of acute leukemia biology and discusses new classification systems that have arisen as a result of emerging insights into pathogenesis. Estey, Faderl and Kantarjian, who all work at the respected Anderson Cancer Center in Houston, Texas, USA, examine in detail advances in the treatment of particular types of acute leukemia. Their book also covers the management of acute leukemia in general as well as the development of new therapies. This book will be extremely useful to clinicians.

Author : Mitchell S. Cairo,Sherrie L. Perkins
Publisher : World Scientific
Page : 601 pages
File Size : 44,5 Mb
Release : 2012
Category : Medical
ISBN : 9789814299602

Get Book

Hematological Malignancies in Children, Adolescents and Young Adults by Mitchell S. Cairo,Sherrie L. Perkins Pdf

Bringing together intellectual and scientific experts from pediatrics, adolescent medicine, general medicine, pathology, biology, nursing and psychology, this book is the first of its kind to cover the topics of leukemias and lymphomas in young patients ranging from infants to young adults. The content is organized and subdivided into four major sections -- under the main headings of General Considerations, Pathobiology, Clinical Manifestations and Treatment, and Supportive Care and Complications -- for ease of reference to readers. Hematological Malignancies in Children, Adolescents and Young Adults presents a comprehensive multidisciplinary review of the field of hematological malignancies and brings forth illuminating perspectives from an internationally recognized group of leading authorities in the field.

Author : M. Extermann
Publisher : Karger Medical and Scientific Publishers
Page : 178 pages
File Size : 48,7 Mb
Release : 2013-01-18
Category : Medical
ISBN : 9783318023077

Get Book

Cancer and Aging by M. Extermann Pdf

Cancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity of geriatric oncology, several chapters focus on geriatric and oncologic aspects in patient assessment, treatment options, nursing and exercise programs. The book is rounded off by a discussion on the impact of the metabolic syndrome illustrating the interactions between comorbidity and cancer and a chapter on frailty.This book provides the reader with insights that will hopefully foster his or her reflection in their own research and practice to further the development of this most exciting field. Given the aging of the population worldwide and the high prevalence of cancer, it is essential reading not only for oncologists and geriatricians but for all health practitioners.