Nanomaterials For Photodynamic Therapy

Author : Prashant Kesharwani
Publisher : Woodhead Publishing
Page : 570 pages
File Size : 40,9 Mb
Release : 2023-01-14
Category : Technology & Engineering
ISBN : 9780323903547

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Nanomaterials for Photodynamic Therapy by Prashant Kesharwani Pdf

Nanomaterials for Photodynamic Therapy takes a unique approach to this area, with a key focus on the use of nanomaterials and nanocarriers for photodynamic therapy (PDT). The book introduces the history and mechanism of action behind PDT, covering the variety of sensitizers currently available. Subsequent chapters review existing and emerging nanomaterials for PDT, including hydrogel nanocomposites, fullerenes, quantum dots, polymeric micelles, and more. Challenges and translational aspects of PDT are also discussed, touching on the issues and hindrances of drug resistant cancers.The book bridges the gap between the physics and clinical aspects of PDT, offering a unique nanomaterials-focused perspective. This book will prove useful for materials scientists, biomedical engineers, electrical and optical engineers, and pharmaceutical scientists interested in cancer treatment. Reviews a broad range of nanomaterials for PDT, such as graphene oxide, dendrimers, solid lipid nanoparticles, and more Provides a helpful introduction to the history and mechanism of action behind PDT Discusses challenges in clinical translational, particularly in drug-resistant cancers

Author : Natalia Mayumi Inada,Hilde Harb Buzzá,Kate Cristina Blanco,Lucas Danilo Dias,Giulia Kassab
Publisher : BoD – Books on Demand
Page : 243 pages
File Size : 46,7 Mb
Release : 2021-05-05
Category : Science
ISBN : 9781839680601

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Photodynamic Therapy by Natalia Mayumi Inada,Hilde Harb Buzzá,Kate Cristina Blanco,Lucas Danilo Dias,Giulia Kassab Pdf

Today, in the face of resistant microorganisms, aggressive cancers unresponsive to conventional treatments, and the COVID-19 pandemic, the need for advanced and innovative protocols for combating and treating disease is paramount. This book presents basic concepts of photodynamic therapy along with data from clinical research on its use in treating oncologic and other diseases. It also presents innovative strategies in photodynamic therapy, including information on polymer nanoparticles. This book was prepared with great care and by many valuable hands so that we can expand the dissemination of Photodynamic Therapy, as well as motivate for new research.

Author : Michael R. Hamblin,Pinar Avci
Publisher : Elsevier
Page : 220 pages
File Size : 55,8 Mb
Release : 2015-02-17
Category : Science
ISBN : 9781908818782

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Applications of Nanoscience in Photomedicine by Michael R. Hamblin,Pinar Avci Pdf

Nanoscience has become one of the key growth areas in recent years. It can be integrated into imaging and therapy to increase the potential for novel applications in the field of photomedicine. In the past commercial applications of nanoscience have been limited to materials science research only, however, in recent years nanoparticles are rapidly being incorporated into industrial and consumer products. This is mainly due to the expansion of biomedical related research and the burgeoning field of nanomedicine. Applications of Nanoscience in Photomedicine covers a wide range of nanomaterials including nanoparticles used for drug delivery and other emerging fields such as optofluidics, imaging and SERS diagnostics. Introductory chapters are followed by a section largely concerned with imaging, and finally a section on nanoscience-enabled therapeutics. Covers a comprehensive up-to-date information on nanoscience Focuses on the combination of photomedicine with nanotechnology to enhance the diversity of applications Pioneers in the field have written their respective chapters Opens a plethora of possibilities for developing future nanomedicine Easy to understand and yet intensive coverage chapter by chapter

Author : Ganesh S. Kamble
Publisher : John Wiley & Sons
Page : 452 pages
File Size : 51,7 Mb
Release : 2022-03-14
Category : Technology & Engineering
ISBN : 9783527346776

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2D Functional Nanomaterials by Ganesh S. Kamble Pdf

2D Functional Nanomaterials Outlines the latest developments in 2D heterojunction nanomaterials with energy conversion applications In 2D Functional Nanomaterials: Synthesis, Characterization, and Applications, Dr. Ganesh S. Kamble presents an authoritative overview of the most recent progress in the rational design and synthesis of 2D nanomaterials and their applications in semiconducting catalysts, biosensors, electrolysis, batteries, and solar cells. This interdisciplinary volume is a valuable resource for materials scientists, electrical engineers, nanoscientists, and solid-state physicists looking for up-to-date information on 2D heterojunction nanomaterials. The text summarizes the scientific contributions of international experts in the fabrication and application of 2D nanomaterials while discussing the importance and impact of 2D nanomaterials on future economic growth, novel manufacturing processes, and innovative products. Provides thorough coverage of graphene chemical derivatives synthesis and applications, including state-of-the-art developments and perspectives Describes 2D/2D graphene oxide-layered double hydroxide nanocomposites for immobilization of different radionuclides Covers 2D nanomaterials for biomedical applications and novel 2D nanomaterials for next-generation photodetectors Discusses applications of 2D nanomaterials for cancer therapy and recent trends ingraphene-latex nanocomposites Perfect for materials scientists, inorganic chemists, and electronics engineers, 2D Functional Nanomaterials: Synthesis, Characterization, and Applications is also an essential resource for solid-state physicists seeking accurate information on recent progress in two-dimensional heterojunction materials with energy conversion applications.

Author : Wansong Chen,Xiaoli Wei,Jianhua Zhang
Publisher : Frontiers Media SA
Page : 201 pages
File Size : 49,6 Mb
Release : 2021-05-18
Category : Science
ISBN : 9782889667765

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Functional Nanomaterials for Cancer Diagnostics and Therapy by Wansong Chen,Xiaoli Wei,Jianhua Zhang Pdf

Author : Manzar Abbas,Atia Atiq,Muhammad Ovais,Michael R Hamblin
Publisher : Elsevier
Page : 274 pages
File Size : 46,6 Mb
Release : 2023-09-15
Category : Technology & Engineering
ISBN : 9780323957595

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Organic Nanomaterials for Cancer Phototheranostics by Manzar Abbas,Atia Atiq,Muhammad Ovais,Michael R Hamblin Pdf

Organic Nanomaterials for Cancer Phototheranostics highlights the use of biocompatible building blocks to make nanomaterials that can aid in medical treatment through better diagnostic and antitumor efficacy. It synthesizes the current literature on synthetic strategies and designs based on peptides, proteins, polymers, lipids, and their conjugates, as well as composites and complexes with metals and inorganic components used to form the nanomaterials. Mechanistic approaches, clinical problems, and therapeutic and diagnostics mechanisms are covered in each chapter. Cellular interactions and uptake, pharmacokinetics, biodistribution, drug delivery efficiency, and safety concerns of these types of nanomaterials are discussed, as well. Other topics looked at include photostability, clearance, metabolism, in-vitro and in-vivo mechanisms, therapeutic efficacy, imaging, and toxicology. Outlines fabrication and design strategies of peptides, proteins, polymers, lipids, composites, and complexes with metals and inorganic components Discusses the limitations and challenges of organic nanomaterials in clinical use, including their mechanisms of penetration into cancer cells and tissue, photostability, clearance, and metabolism Covers clinical problems and therapeutic and diagnostics mechanisms

Author : Flora Fitzgerald
Publisher : Nova Biomedical Books
Page : 0 pages
File Size : 49,6 Mb
Release : 2017
Category : Photochemotherapy
ISBN : 1536119121

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Photodynamic Therapy (PDT) by Flora Fitzgerald Pdf

As a new concept of cancer treatment, photodynamic therapy (PDT) has gained great attention in the last few decades. Compared to classical treatments such as surgery, chemotherapy and radiotherapy, PDT is a noninvasive, localized treatment of lesions that shows fewer side effects and has low systemic toxicity. In Chapter One, the basic mechanisms, applications and functional nanomaterials-based drug delivery systems for photodynamic therapy of cancer are reviewed. Chapter Two summarizes the application of different carbon based nanomaterials as agents for PDT and discusses current state-of-the-art use of fullerenes and their derivatives, carbon nanotubes and graphene quantum dots in PDT. Chapter Three covers the benefits and pitfalls of using chemi- and bioluminescent systems as intracellular excitation sources in PDT. Bioluminescence is a widespread natural phenomenon, which consists on emission of light resulting from the oxidation of a substrate in a reaction catalyzed by an enzyme in a biological system. Chapter Four addresses in the synthesis, characterization, and photodynamic activity of a novel hydrophobic photosensitizer 5,10,15,20-tetrakis(benzo[b]thiophene) Porphyrin (BTP) and water soluble photosensitizer 5,10,15,20-Tetrakis(7- sulfonatobenzo[b]thiophene) Porphyrin (SBTP). The authors lab is engaged in the synthesis of PDT molecules incorporating benzothiophene moiety to the meso-position of porphyrin molecules. Chapter Five discusses the Guidelines for Gastroenterological Endoscopy in Patients on Oral Antithrombotic Treatment established by the Japan Gastroenterological Endoscopy Society (JGES).These guidelines classify endoscopic interventions according to the risk of hemorrhage and specify the management of various antithrombotic drugs. Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are classified as high-risk procedures for hemorrhage, but PDT is not included in the guidelines. Because PDT causes ischemic necrosis of tumor tissue, the authors say this could possibly be performed safely in patients on oral antithrombotic therapy. The authors of Chapter Six developed a method of the initial concentration of protoporphyrin-IX in the operated removing glioblastoma tissue using the calibration curve of the fluorescent intensity and the known Pp-IX concentration in order to estimate of the more correlated with the cure rate.

Author : Yohei Tanaka
Publisher : BoD – Books on Demand
Page : 264 pages
File Size : 49,6 Mb
Release : 2017-05-17
Category : Medical
ISBN : 9789535131557

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Photomedicine by Yohei Tanaka Pdf

Photomedicine is one of the most inspiring and interdisciplinary fields in medicine that involves the research and application of photobiology with respect to health and disease. Photomedicine has contributed to the clinical practice of a variety of medical fields, including dermatology, surgery, radiology, diagnostics, cardiology, and anticancer therapy. Furthermore, expansion of its scope and contribution can be expected. This book covers a wide range of aspects and issues related to photomedicine, which brings together researchers from many countries. These include the basic science of photodynamic therapy, clinical applications in various kinds of medical fields, photochemotherapy, laser therapy for musculoskeletal pain, intense pulsed light therapy for photorejuvenation, biological function of low-level laser therapy, and photobiology for skin rejuvenation. Not only will this be beneficial for readers, but it will also contribute to scientists making further breakthroughs in photomedicine.

Author : Mingqian Tan,Aiguo Wu
Publisher : World Scientific
Page : 430 pages
File Size : 47,6 Mb
Release : 2016
Category : Health & Fitness
ISBN : 9789814635424

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Nanomaterials for Tumor Targeting Theranostics by Mingqian Tan,Aiguo Wu Pdf

"Nanomaterials offer great potential for effective tumor diagnosis and therapy combing diagnostic agents and therapeutic drugs into one platform. In this book, the most recent progress of main nanomaterials and their applications in tumor targeting theranostics is presented. It summarizes the recent advances of current principal nanomaterials in tumor theranostics, including magnetic nanomaterials, quantum dots, mesoporous silica nanoparticles, gold nanomaterials, polymeric nanosystem, carbon nanomaterials, lipopolyplex nanoparticles, microbubbles, upconversion nanomaterials and dendrimers. It will enable readers to get a more realistic understanding of both the advantages and limitations of nanomaterials for potential tumor targeting theranosis. The publication of this book will accelerate the spread of ideas that are currently trickling through the scientific literature. Also a greater understanding of the potential and challenge of nanomaterials for tumor targeting theranostics is highly anticipated for practical clinical use."--Provided by publisher.

Author : Michael R. Hamblin
Publisher : Artech House
Page : 601 pages
File Size : 55,5 Mb
Release : 2008
Category : Medical
ISBN : 9781596932784

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Advances in Photodynamic Therapy by Michael R. Hamblin Pdf

With today's focus on targeted and minimally invasive therapies, photodynamic therapy (PDT) is now being studied and used to combat many disease states and to investigate critical biological questions. This groundbreaking resource brings you the latest advances in photodynamic therapy and offers you a solid understanding of the design, delivery and dosimetry of the three basic ingredients of PDT - photosensitizers, light and oxygen. The book covers novel areas of mechanistic and innovative translational approaches. Moreover, it gives you an overview of the important medical applications of PDT, including approved treatments, clinical trials, and investigated therapies for cancer and non-malignant diseases.

Author : Gil Gonçalves,Gerard Tobias
Publisher : Springer
Page : 455 pages
File Size : 51,5 Mb
Release : 2018-06-01
Category : Technology & Engineering
ISBN : 9783319898780

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Nanooncology by Gil Gonçalves,Gerard Tobias Pdf

This book presents a systematic overview of the most relevant nanomaterials and their respective intrinsic properties that have been highly explored by the scientific community and pharmaceutical companies in several different modalities for cancer therapy and bioimaging. The chapters explore the synergistic effects provided by the different nanostructured materials and highlight the main in vitro and in vivo therapeutic achievements on cancer. This work also provides relevant discussion about the recent progresses and future challenges that nanotechnology faces on the conception of more efficient nanoformulations against primary tumors, circulating cancer cells and metastases.

Author : Mahendra Rai, Ph.D,Ranjita Shegokar, Ph.D
Publisher : Springer
Page : 493 pages
File Size : 41,6 Mb
Release : 2017-11-14
Category : Medical
ISBN : 9783319637907

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Metal Nanoparticles in Pharma by Mahendra Rai, Ph.D,Ranjita Shegokar, Ph.D Pdf

Completely dedicated to the biomedical applications of metal nanoparticles, this book covers the different toxicity problems found in healthcare situations and also provides comprehensive info on the use of metal nanoparticles in treating various diseases. Metal Nanoparticles in Pharma is the first edited volume to set up the discussion for a clinical setting and to target a pharmaceutical audience of academic and industry-based researchers.

Author : Piyush Kumar,Rohit Srivastava
Publisher : Springer
Page : 68 pages
File Size : 52,7 Mb
Release : 2016-11-21
Category : Technology & Engineering
ISBN : 9783319458267

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Nanomedicine for Cancer Therapy by Piyush Kumar,Rohit Srivastava Pdf

This Brief focuses on the cancer therapy available till date, from conventional drug delivery to nanomedicine in clinical trial. In addition, it reports on future generation based nanotherapeutics and cancer theranostic agent for effective therapeutic diagnosis and treatment. Breast cancer was chosen as the model system in this review. The authors give emphasis to multiple drug resistance (MDR) and its mechanism and how to overcome it using the nanoparticle approach.

Author : Fan Zhang
Publisher : Springer
Page : 428 pages
File Size : 48,5 Mb
Release : 2014-12-11
Category : Technology & Engineering
ISBN : 9783662455975

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Photon Upconversion Nanomaterials by Fan Zhang Pdf

This book introduces the latest advances made in both fundamental studies and potential applications of upconversion nanomaterials, particularly in the field of high-resolution in vitro bioanalysis and in vivo imaging. This book starts with the synthesis and characterization, and focuses on applications ranging from materials science to biology. Above all, it describes cutting-edge advances in upconversion nanophosphor (UCNP)-based applications in multiplexed encoding, guest delivery and release systems, photodynamic therapy (PDT), solar cells, photocatalysis and so on. The major barriers that currently prevent UCNPs from being used in mainstream applications are also presented in detail.

Author : Michael R. Hamblin
Publisher : Momentum Press
Page : 65 pages
File Size : 45,8 Mb
Release : 2012-12-17
Category : Technology & Engineering
ISBN : 9781606504161

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Photodynamic Therapy Mediated by Fullerenes and their Derivatives by Michael R. Hamblin Pdf

The fullerene molecule with its unique structure of 60 carbon atoms arranged in a soccer ball structure is a molecule of great potential for a variety of applications and has drawn attention of lots of physicists, chemists and engineers. Recently, these nanostructures have also been studied for their biological activities with a view towards using them for biomedical applications. One of the possible therapies for which fullerenes may have a real medical application is the light based therapy called photodynamic therapy (PDT), which is a non-surgical, minimally invasive approach that has been used in the treatment of solid tumors and many non-malignant diseases.