Photodynamic Therapy Mediated By Fullerenes And Their Derivatives

Author : Michael R. Hamblin
Publisher : Momentum Press
Page : 65 pages
File Size : 47,8 Mb
Release : 2012-12-17
Category : Technology & Engineering
ISBN : 9781606504161

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Photodynamic Therapy Mediated by Fullerenes and their Derivatives by Michael R. Hamblin Pdf

The fullerene molecule with its unique structure of 60 carbon atoms arranged in a soccer ball structure is a molecule of great potential for a variety of applications and has drawn attention of lots of physicists, chemists and engineers. Recently, these nanostructures have also been studied for their biological activities with a view towards using them for biomedical applications. One of the possible therapies for which fullerenes may have a real medical application is the light based therapy called photodynamic therapy (PDT), which is a non-surgical, minimally invasive approach that has been used in the treatment of solid tumors and many non-malignant diseases.

Author : Mike Hamblin,Hamblin
Publisher : Unknown
Page : 0 pages
File Size : 47,6 Mb
Release : 2012-10-31
Category : Fullerenes
ISBN : 1606504266

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Photodynamic Therapy Mediated by Fullerenes and Their Derivatives by Mike Hamblin,Hamblin Pdf

The Fullerene molecule is a carbon-based nano-scale structure of 60 carbon atoms arranged in a 3-dimensional soccer ball- like sphere. It is highly stable, but it can be modified with functional groups for desired biological activity. This new monograph in the ASME-Momentum Press series on Biomedical & Nanomedical Technologies will explore the basic physics and chemistry of Fullerenes, how the Fullerene molecule can be chemically modified with bio-active moieties, and then how it can be applied in clinical use. Examples of antimicrobial and anti-cancer uses will be discussed.

Author : Lucas F de Freitas,Michael R Hamblin
Publisher : Morgan & Claypool Publishers
Page : 105 pages
File Size : 51,8 Mb
Release : 2016-04-01
Category : Science
ISBN : 9781681740553

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Antimocrobial Photodynamic Inactivation and Antitumor Photodynamic Therapy with Fullerenes by Lucas F de Freitas,Michael R Hamblin Pdf

This book provides detailed and current information on using fullerenes (bucky-balls) in photodynamic therapy (PDT), one of the most actively studied applications of photonic science in healthcare. This will serve as a useful source for researchers working in photomedicine and nanomedicine, especially those who are investigating PDT for cancer treatment and infectious disease treatment. The book runs the gamut from an introduction to the history and chemistry of fullerenes and some basic photochemistry, to the application of fullerenes as photosensitizers for cancer and antimicrobial inactivation.

Author : L Karthik,A. Vishnu Kirthi,Shivendu Ranjan,V. Mohana Srinivasan
Publisher : CRC Press
Page : 299 pages
File Size : 49,7 Mb
Release : 2019-12-06
Category : Medical
ISBN : 9780429555787

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Biological Synthesis of Nanoparticles and Their Applications by L Karthik,A. Vishnu Kirthi,Shivendu Ranjan,V. Mohana Srinivasan Pdf

Biological Synthesis of Nanoparticles and Their Applications gives insight into the synthesis of nanoparticles utilizing the natural routes. It demonstrates various strategies for the synthesis of nanoparticles utilizing plants, microscopic organisms like bacteria, fungi, algae and so forth. It orchestrates interdisciplinary hypothesis, ideas, definitions, models and discoveries associated with complex cell of the prokaryotes and eukaryotes. Highlights: Discusses biological approach towards the nanoparticle synthesis Describes the role of nanotechnology in the field of medicine and its medical devices Covers application and usage of the chemicals at the molecular level to act as catalysts and binding products for both organic and inorganic Chemical Reactions Reviews application in physics such as solar cells, photovoltaics and other usage Microorganisms can aggregate and detoxify substantial metals because of different reductase enzymes, which can diminish metal salts to metal nanoparticles. The readers after going through this book will have detailed account of mechanism of bio-synthesis of nanoparticles.

Author : Mei Zhang,Rajesh R. Naik,Liming Dai
Publisher : Springer
Page : 576 pages
File Size : 50,7 Mb
Release : 2015-11-06
Category : Technology & Engineering
ISBN : 9783319228617

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Carbon Nanomaterials for Biomedical Applications by Mei Zhang,Rajesh R. Naik,Liming Dai Pdf

This book covers a wide range of topics relating to carbon nanomaterials, from synthesis and functionalization to applications in advanced biomedical devices and systems. As they possess unique and attractive chemical, physical, optical, and even magnetic properties for various applications, considerable effort has been made to employ carbon nanomaterials (e.g., fullerenes, carbon nanotubes, graphene, nanodiamond) as new materials for the development of novel biomedical tools, such as diagnostic sensors, imaging agents, and drug/gene delivery systems for both diagnostics and clinical treatment. Tremendous progress has been made and the scattered literature continues to grow rapidly. With chapters by world-renowned experts providing an overview of the state of the science as well as an understanding of the challenges that lie ahead, Carbon Nanomaterials for Biomedical Applications is essential reading not only for experienced scientists and engineers in biomedical and nanomaterials areas, but also for graduate students and advanced undergraduates in materials science and engineering, chemistry, and biology.

Author : Lucas F de Freitas,Michael R Hamblin
Publisher : Morgan & Claypool Publishers
Page : 86 pages
File Size : 40,8 Mb
Release : 2016-04-01
Category : Science
ISBN : 9781681742472

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Antimocrobial Photodynamic Inactivation and Antitumor Photodynamic Therapy with Fullerenes by Lucas F de Freitas,Michael R Hamblin Pdf

This book provides detailed and current information on using fullerenes (bucky-balls) in photodynamic therapy (PDT), one of the most actively studied applications of photonic science in healthcare. This will serve as a useful source for researchers working in photomedicine and nanomedicine, especially those who are investigating PDT for cancer treatment and infectious disease treatment. The book runs the gamut from an introduction to the history and chemistry of fullerenes and some basic photochemistry, to the application of fullerenes as photosensitizers for cancer and antimicrobial inactivation.

Author : Alexandru Grumezescu
Publisher : William Andrew
Page : 576 pages
File Size : 54,8 Mb
Release : 2016-03-08
Category : Science
ISBN : 9780323428873

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Nanobiomaterials in Antimicrobial Therapy by Alexandru Grumezescu Pdf

Nanobiomaterials in Antimicrobial Therapy presents novel antimicrobial approaches that enable nanotechnology to be used effectively in the treatment of infections. This field has gained a large amount of interest over the last decade, in response to the high resistance of pathogens to antibiotics. Leading researchers from around the world discuss the synthesis routes of nanobiomaterials, characterization, and their applications as antimicrobial agents. The books covers various aspects: mechanisms of toxicity for inorganic nanoparticles against bacteria; the development of excellent carriers for the transport of a high variety of antimicrobials; the use of nanomaterials to facilitate both diagnosis and therapeutic approaches against infectious agents; strategies to control biofilms based on enzymes, biosurfactants, or magnetotactic bacteria; bacterial adhesion onto polymeric surfaces and novel materials; and antimicrobial photodynamic inactivation. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. A methodical approach to this highly relevant subject for researchers, practitioners and students working in biomedical, biotechnological and engineering fields A valuable guide to recent scientific progress and the latest application methods Proposes novel opportunities and ideas for developing or improving technologies in nanomedicine and nanobiology

Author : Prashant Kesharwani
Publisher : Woodhead Publishing
Page : 570 pages
File Size : 55,6 Mb
Release : 2023-01-14
Category : Technology & Engineering
ISBN : 9780323903547

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Nanomaterials for Photodynamic Therapy by Prashant Kesharwani Pdf

Nanomaterials for Photodynamic Therapy takes a unique approach to this area, with a key focus on the use of nanomaterials and nanocarriers for photodynamic therapy (PDT). The book introduces the history and mechanism of action behind PDT, covering the variety of sensitizers currently available. Subsequent chapters review existing and emerging nanomaterials for PDT, including hydrogel nanocomposites, fullerenes, quantum dots, polymeric micelles, and more. Challenges and translational aspects of PDT are also discussed, touching on the issues and hindrances of drug resistant cancers.The book bridges the gap between the physics and clinical aspects of PDT, offering a unique nanomaterials-focused perspective. This book will prove useful for materials scientists, biomedical engineers, electrical and optical engineers, and pharmaceutical scientists interested in cancer treatment. Reviews a broad range of nanomaterials for PDT, such as graphene oxide, dendrimers, solid lipid nanoparticles, and more Provides a helpful introduction to the history and mechanism of action behind PDT Discusses challenges in clinical translational, particularly in drug-resistant cancers

Author : Franco Cataldo,Tatiana da Ros
Publisher : Springer Science & Business Media
Page : 411 pages
File Size : 48,9 Mb
Release : 2008-09-08
Category : Science
ISBN : 9781402068454

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Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes by Franco Cataldo,Tatiana da Ros Pdf

Fullerenes and nanotubes are two classes of carbon structures or allotropes, which were discovered about 17 years ago. Since that time, many chemical derivatives have been synthesized using fullerenes and nanotubes as building blocks. Particularly promising was the theory that the chemical properties of fullerenes, and certain derivatives, made them likely candidates for anticancer drugs, inhibitors of viruses such as HIV, or even as anti-bacterials. Their cyctotoxicity can also be controlled by specific circumstances. In addition, the funtionalization of nanotubes has not only produced relatively simple derivatives, but also complex hybrids with biological macromolecules, which show unique supramolecular architecture and which are promising in many medical applications. The application of fullerenes and nanotubes in medicine is at the frontier of our knowledge, thus the work in this field represents the basis for future novel developments.

Author : Siddhardha Busi,Ram Prasad
Publisher : CRC Press
Page : 377 pages
File Size : 46,6 Mb
Release : 2023-08-22
Category : Medical
ISBN : 9781000925340

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Antimicrobial Photodynamic Therapy by Siddhardha Busi,Ram Prasad Pdf

Antimicrobial Photodynamic Therapy: Concepts and Applications explores the novel antimicrobial therapeutic technique. As the world searches for new, efficient modalities for fighting microorganisms, this book offers a complete understanding of the concept, and knowledge about the emerging technique ‘antimicrobial photodynamic therapy’ (aPDT) for the scientific communities and budding researchers. The book aligns concepts, significance, and applications of the technique systematically. Chapters in the book cover microorganisms, pathogenesis, conventional treatment methods, and significance of new treatment approaches to the concept of antimicrobial photodynamic therapy. The authors describe the mechanism behind it, with applications and examples from research studies. The book discusses photosensitisers in detail, with one chapter emphasising natural photosensitisers. Use of nanostructures in the antimicrobial photodynamic therapy is elaborated on, and we conclude with a well-explored application of the therapeutic technique in dentistry. Features: Efficiently covers the topic in detail with scientifically proven examples. Applications of the therapeutic approach are well discussed, and readers can learn about the research gaps, challenges, and future of the technique. Starts from basics, enabling readers to understand why the approach is relevant and important for study. Simplistic elucidated concepts and applications make it accessible at all levels.

Author : Xing Lu,Takeshi Akasaka,Zdeněk Slanina
Publisher : Springer Nature
Page : 1029 pages
File Size : 54,9 Mb
Release : 2022-09-24
Category : Science
ISBN : 9789811689949

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Handbook of Fullerene Science and Technology by Xing Lu,Takeshi Akasaka,Zdeněk Slanina Pdf

Nanocarbon chemistry and physics is a fast-developing, broad research area – the Nobel prizes in 1996 and 2010 awarded to two key discoveries in the field, and several other nanocarbon achievements of comparable importance. Owing to this rapid growth, the nanocarbon landscape fundamentally changes every few years, creating a need to survey the field on a regular basis to update the books that have become incomplete or even obsolete. As such, this book focuses on fullerenes and metallofullerenes and also on the related areas of nanotubes and graphenes. All the covered research topics provide important fundamental knowledge for the natural sciences, but also for applications in molecular electronics, superconductivity, catalysis, photovoltaics and medical diagnostics. The current nanocarbon research activities have particularly high application potential in the conversion of solar energy, future molecular memories, non-conventional materials for optoelectronics, and new treatments for civilization diseases. Offering a truly up-to-date critical survey of nanocarbon science, its concepts and highlights, it follows the concept of a handbook: it addresses key topics systematically, from historical background, methodological aspects, current important issues, and application potential, all supplied with extensive referencing. With individual chapters written by leading experts with extensive research experience, it is a comprehensive reference resource for graduate students and active researchers alike.

Author : Klaus D. Sattler
Publisher : CRC Press
Page : 888 pages
File Size : 41,7 Mb
Release : 2010-09-17
Category : Science
ISBN : 9781420075496

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Handbook of Nanophysics by Klaus D. Sattler Pdf

The tools of nanodiagnostics, nanotherapy, and nanorobotics are expected to revolutionize the future of medicine, leading to presymptomatic diagnosis of disease, highly effective targeted treatment therapy, and minimum side effects. Handbook of Nanophysics: Nanomedicine and Nanorobotics presents an up-to-date overview of the application of nan

Author : Electrochemical Society. Fullerenes Group,Electrochemical Society. Meeting
Publisher : The Electrochemical Society
Page : 292 pages
File Size : 54,6 Mb
Release : 2000
Category : Dielectrics
ISBN : 1566772761

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Functionalized Fullerenes by Electrochemical Society. Fullerenes Group,Electrochemical Society. Meeting Pdf

Author : Anton Ficai,Alexandru Mihai Grumezescu
Publisher : Elsevier
Page : 722 pages
File Size : 52,8 Mb
Release : 2017-05-29
Category : Medical
ISBN : 9780323461511

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Nanostructures for Antimicrobial Therapy by Anton Ficai,Alexandru Mihai Grumezescu Pdf

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Author : Chandra P Sharma
Publisher : Elsevier
Page : 451 pages
File Size : 45,8 Mb
Release : 2018-08-22
Category : Medical
ISBN : 9780323509237

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Drug Delivery Nanosystems for Biomedical Applications by Chandra P Sharma Pdf

Drug Delivery Nanosystems for Biomedical Application reviews some of the most challenging nanosystems with different routes of delivery that are useful for specific drugs, from both efficacy and bioavailability points-of-view. The chapters explore how this area is developing, the present state of the field, and future developments, in particular, inorganic, metallic, polymeric, composite and lipid nanosystems and their possible evolution to clinical applications. The book is a valuable research reference for both researchers and industrial partners who are not only interested in learning about this area, but also want to gain insights on how to move towards translational research. Focuses on applications, including tissue engineering and regenerative technologies, showing how nanosystems are used in practice Explores how nanosystems are used to deliver a variety of drugs, including peptides, hormone growth factors and genes Assesses the safety and nanotoxicity aspects of drug delivery nanosystems