Natural Metal Fiber And Macromolecular Carcinogens

Author : Yin-Tak Woo,David Y. Lai,Joseph C. Arcos
Publisher : Academic Press
Page : 898 pages
File Size : 40,9 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483216027

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Natural, Metal, Fiber, and Macromolecular Carcinogens by Yin-Tak Woo,David Y. Lai,Joseph C. Arcos Pdf

Chemical Induction of Cancer: Structural Bases and Biological Mechanisms, Volume IIIC: Natural, Metal, Fiber, and Macromolecular Carcinogens covers structure-carcinogenicity relationships of carcinogenic mycotoxins, carcinogenic substances generated by plants, carcinogenic metals and metalloids, and foreign-body carcinogens. The book discusses the metabolism and mechanism of carcinogenic action, physicochemical properties, other biological activities (principally mutagenicity and teratogenicity), modification of carcinogenic activity, formation and environmental significance. The text also describes the carcinogenic water-soluble high polymers and explores the intriguing problems of the carcinogenic effect of osmotic imbalance in tissue microenvironment, as well as of spontaneous malignant transformation occurring in cell cultures in vitro. Studies on tumor induction and carcinogenesis modification by nonviral nucleic acids, by nucleases, proteases, histones, and by antigenic stimulation as well as by antibodies are also considered. The book further tackles tumor-released factors as possible modifiers of carcinogenesis. The text will prove invaluable to chemists and people involved in cancer research.

Author : Joseph C. Arcos,David Y. Lai,Mary F. Argus,Yin-Tak Woo
Publisher : Unknown
Page : 869 pages
File Size : 43,5 Mb
Release : 1988
Category : Electronic
ISBN : OCLC:740072940

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Natural, Metal, Fiber, and Macromolecular Carcinogens by Joseph C. Arcos,David Y. Lai,Mary F. Argus,Yin-Tak Woo Pdf

Author : Joseph C. Arcos
Publisher : Unknown
Page : 869 pages
File Size : 43,8 Mb
Release : 1968
Category : Carcinogenesis
ISBN : 012059353X

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Chemical Induction of Cancer by Joseph C. Arcos Pdf

Author : Romualdo Benigni
Publisher : CRC Press
Page : 441 pages
File Size : 48,6 Mb
Release : 2003-02-26
Category : Medical
ISBN : 9781135505691

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Quantitative Structure-Activity Relationship (QSAR) Models of Mutagens and Carcinogens by Romualdo Benigni Pdf

Applied with success in a number of areas, QSAR studies have become particularly popular in the rational design of drugs and pesticides. Much has been published on the principles of QSAR in this area, but not on their application s to toxic chemicals. This book provides the first comprehensive, interdisciplinary presentation of QSAR studies on

Author : Edward J. Massaro
Publisher : CRC Press
Page : 1196 pages
File Size : 43,6 Mb
Release : 1997-07-09
Category : Medical
ISBN : 143980575X

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Handbook of Human Toxicology by Edward J. Massaro Pdf

Covering some of the most important topics in modern toxicology, the Handbook of Human Toxicology is a unique and valuable addition to the current literature. It addresses issues, answers questions, and provides data related to. Within each of these five major sections are several carefully selected topics that reflect the current state of human to

Author : Anonim
Publisher : Unknown
Page : 248 pages
File Size : 44,6 Mb
Release : 1994
Category : Aromatic amines
ISBN : IND:30000143535924

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Carcinogenic and Mutagenic N-substituted Aryl Compounds by Anonim Pdf

Author : Wai Nang Choy
Publisher : CRC Press
Page : 441 pages
File Size : 53,5 Mb
Release : 2001-08-31
Category : Medical
ISBN : 9781135554200

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Genetic Toxicology and Cancer Risk Assessment by Wai Nang Choy Pdf

Presents state-of-the-art regulatory cancer risk assessment models including a biologically based model for two-hit carcinogenesis and cell proliferation! This book comprehensively reviews the various roles of genetic toxicology in human cancer risk assessment conducted by United States and worldwide regulatory agencies-discussing hazard ide

Author : OECD
Publisher : OECD Publishing
Page : 85 pages
File Size : 48,9 Mb
Release : 2017-04-13
Category : Electronic
ISBN : 9789264274792

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OECD Series on Testing and Assessment Fundamental And Guiding Principles For (Q)SAR Analysis Of Chemical Carcinogens with Mechanistic Considerations by OECD Pdf

In this document the importance of mechanistic consideration in quantitative structure-activity relationship ((Q)SAR) analysis, the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches of combining chemoinformatics and ...

Author : Joseph C. Arcos,Mary F. Argus,Yin-tak Woo
Publisher : Springer Science & Business Media
Page : 748 pages
File Size : 53,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461240761

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Chemical Induction of Cancer by Joseph C. Arcos,Mary F. Argus,Yin-tak Woo Pdf

In the approach to the analysis of disease, including, of course, cancer, two major thrusts may be distinguished. These may be referred to, in shorthand, as agents and processes: the causative agents (chemical, microbial, physical, environmental, and psychosocial) and the organismic processes, initiated and furthered by the agents, culminating in observable pathology (at the macromolecular, cytological, histological, organ function, locomotor, and behavioral levels). The past 25 years, since the appearance of the first volume of the predecessor series (1) authored by the Editors of this present volume, have seen an impressive number of studies on chemicals (and other agents) as etiologic factors in the induction of cancer. The major emphasis has been on the discovery of many chemical carcinogens of widely different structures, their metabolism by various tissues and cells, and, in turn, their molecular-biochemical effects on the cells. This rapidly expanded body of information, as effectively covered in the predecessor volumes, is an excellent entree to the second half of the overall problem of chemical carcinogenesis, the processes. The active agents trigger a large array of molecular-biochemical alterations to which the target cells, target tissues, and target organisms respond in many select and common ways. This second major aspect of the induction of cancer by chemicals (and by other agents)- the sequence of cellular and tissue changes clearly relevant to cancer-remains the challenge for the future.

Author : Anna M. Fan,George Alexeeff,Elaine Khan
Publisher : CRC Press
Page : 1426 pages
File Size : 54,8 Mb
Release : 2015-03-04
Category : Medical
ISBN : 9789814613392

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Toxicology and Risk Assessment by Anna M. Fan,George Alexeeff,Elaine Khan Pdf

The presence of chemicals in our environment is a subject of intense interest owing to the many potential adverse health effects to humans following exposure to these chemicals. The principles and practices of risk assessment are used to assess the associated health risks to provide a scientific and health basis for guidance or regulatory standards development and risk management decision making for public health protection. This book compiles, discusses, and presents cutting-edge research data and methodology in performing risk assessment of some major chemicals of concern in our environment. It also discusses the complexity of the scientific databases, the available and updated methodology, emerging issues, limitations in knowledge and methods, considerations of developmental and age sensitivities, use of defaults, case samples on results in risk assessment and risk management, and current and future perspectives. The editors are prominent in the field of environmental toxicology, risk assessment, and chemical regulations. This book will appeal to those interested in evaluating the human health effects of exposure to chemicals in the environment and the associated assessments and findings.

Author : Anonim
Publisher : Unknown
Page : 508 pages
File Size : 41,6 Mb
Release : 1993
Category : Environmental health
ISBN : MINN:31951P00378592X

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Environmental Health Perspectives by Anonim Pdf

Author : Michael Aschner,Lucio G. Costa
Publisher : Academic Press
Page : 450 pages
File Size : 45,9 Mb
Release : 2015-06-18
Category : Technology & Engineering
ISBN : 9780128004074

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Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders by Michael Aschner,Lucio G. Costa Pdf

Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders presents a state-of-the-art review of the effects of environmental contaminants on the development and degeneration of the human nervous system, brought together by world-leading experts in the field. Part One describes the adverse effects that the environment can have on neurological development, and how these effects may exhibit. Specific contaminants and their possible consequences of exposure are addressed (lead, methylmercury, alcohol), as well as specific disorders and the environmental factors associated with them, such as the effect of diet on attention deficit and hyperactivity disorders. Part Two tackles neurodegenerative disorders, specifically addressing their potential neurotoxic origins, and discussing the increasing interest in the effects that early exposure may have in later life. Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders is an invaluable reference for those professionals working in the fields of toxicology, environmental health and neuroscience. Provides, for the first time, the cutting-edge theory of environmental impacts on both neurodegenerative and neurodevelopmental disorders Written by an international selection of the world’s foremost experts in the field of neurotoxicology Full-colour throughout, providing accurate and illustrative examples of neurotoxic effects in action An invaluable reference for those professionals working in the fields of toxicology, environmental health, and neuroscience

Author : Anonim
Publisher : Unknown
Page : 44 pages
File Size : 51,6 Mb
Release : 1989
Category : Environmental health
ISBN : UIUC:30112104625477

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Environmental Health and Toxicology by Anonim Pdf

Author : Wayne G. Landis,Jane S. Hughes,Michael Anthony Lewis
Publisher : ASTM International
Page : 430 pages
File Size : 44,7 Mb
Release : 1993
Category : Environmental health
ISBN : 9780803118607

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Environmental Toxicology and Risk Assessment by Wayne G. Landis,Jane S. Hughes,Michael Anthony Lewis Pdf

Author : Valda M. Craddock
Publisher : Cambridge University Press
Page : 304 pages
File Size : 42,7 Mb
Release : 1993-06-10
Category : Medical
ISBN : 052137393X

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Cancer of the Esophagus by Valda M. Craddock Pdf

The book deals with the esophagus and with the histological and genetic changes accompanying the development of esophageal cancer in humans and animals.