Natural Product Synthesis I

Author : Jie Jack Li,E.J. Corey
Publisher : Springer Science & Business Media
Page : 292 pages
File Size : 51,6 Mb
Release : 2013-03-14
Category : Science
ISBN : 9783642340659

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Total Synthesis of Natural Products by Jie Jack Li,E.J. Corey Pdf

'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.

Author : Johann H. Mulzer
Publisher : Springer Science & Business Media
Page : 258 pages
File Size : 55,8 Mb
Release : 2005-01-12
Category : Medical
ISBN : 354021125X

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Natural Product Synthesis I by Johann H. Mulzer Pdf

B. Basler, S. Brandes, A. Spiegel and T. Bach: Total Synthesis of Kalsoene and Preussin .- R. Bandichhor, B. Nosse and O. Reiser: Paraconic Acids- the Natural Products from Lichen Symbiont .- M. Hiersemann and H. Helmboldt: Recent Progress in the Total Synthesis of Dolabellane and Dolastane Diterpenes .- L. Wessjohann and E. Ruijter: Strategies for Total and Diversity- Oriented Synthesis of Natural Product (-Like) Macrolides .-M. Sefkow: Enantioselectice Synthesis of C(8)-Hydroxylated Lignans: Early Approaches and Recent Advances

Author : Janine Cossy,Stellios Arseniyadis,Christophe Meyer
Publisher : John Wiley & Sons
Page : 413 pages
File Size : 49,9 Mb
Release : 2011-09-22
Category : Science
ISBN : 9783527642083

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Metathesis in Natural Product Synthesis by Janine Cossy,Stellios Arseniyadis,Christophe Meyer Pdf

Emphasizing the impact of metathesis in natural product synthesis through the different types of key reactions, this is a comprehensive view of a hot topic. Written by top international authors, this ready reference is clearly structured and packed with important information, including representative experimental procedures for practical applications. A real must-have for anyone working in natural product synthesis.

Author : Krishna C. Majumdar,Shital K. Chattopadhyay
Publisher : John Wiley & Sons
Page : 648 pages
File Size : 49,5 Mb
Release : 2011-06-15
Category : Science
ISBN : 9783527634897

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Heterocycles in Natural Product Synthesis by Krishna C. Majumdar,Shital K. Chattopadhyay Pdf

Filling a gap on the market, this handbook and ready reference is unique in its discussion of the usefulness of various heterocyclic systems in the synthesis of natural products. Clearly structured for easy access to the information, each chapter is devoted to a certain class of heterocycle, providing a tabular presentation of the natural products to be covered containing the particular heterocyclic ring system along with their biological profile, occurrence and most important physical properties, backed by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products ic covered in detail. Of great interest to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry.

Author : Anne E. Osbourn,Virginia Lanzotti
Publisher : Springer Science & Business Media
Page : 588 pages
File Size : 52,7 Mb
Release : 2009-07-07
Category : Science
ISBN : 9780387854984

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Plant-derived Natural Products by Anne E. Osbourn,Virginia Lanzotti Pdf

Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.

Author : Atta-ur- Rahman
Publisher : Elsevier
Page : 421 pages
File Size : 52,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9780444595157

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Studies in Natural Products Chemistry by Atta-ur- Rahman Pdf

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. With articles written by leading authorities in their respective fields of research, Studies in Natural Products Chemistry, Volume 37 presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable source for researchers and engineers working in natural products and medicinal chemistry. Describes the chemistry of bioactive natural products Contains contributions by leading authorities in the field A valuable source for researchers and engineers working in natural product and medicinal chemistry

Author : Ari M. P. Koskinen
Publisher : John Wiley & Sons
Page : 415 pages
File Size : 43,7 Mb
Release : 2012-06-15
Category : Science
ISBN : 9781118347331

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Asymmetric Synthesis of Natural Products by Ari M. P. Koskinen Pdf

Asymmetric Synthesis of Natural Products, 2nd Edition introduces students to this rapidly growing field of organic chemistry. The initial chapters present the foundations of asymmetric synthesis, including the theory and applications of individual asymmetric reactions. This is followed by chapters on each of the major individual classes of natural products; their structures, biosynthesis and interrelationships as well as examples of asymmetric syntheses and the practical value of these compounds. Natural product classes covered include carbohydrates, amino acids, peptides, proteins, nucleosides, nucleotides, nucleic acids, polyketides, isoprenoids, shikamic acid derivatives and alkaloids. For this second edition the text has been thoroughly updated and expanded, and includes new discussions and examples covering atom and redox economies, practical aspects and environmental awareness. Organocatalysis has emerged completely in the last ten years, and has been fully integrated into this new edition.

Author : Koji Nakanishi,Kōji Nakanishi
Publisher : University Science Books
Page : 720 pages
File Size : 45,9 Mb
Release : 1974
Category : Science
ISBN : 0935702148

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Natural Products Chemistry by Koji Nakanishi,Kōji Nakanishi Pdf

Author : Sujata V. Bhat,B.A. Nagasampagi,Meenakshi Sivakumar
Publisher : Springer Science & Business Media
Page : 886 pages
File Size : 53,5 Mb
Release : 2005-01-04
Category : Science
ISBN : 3540406697

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Chemistry of Natural Products by Sujata V. Bhat,B.A. Nagasampagi,Meenakshi Sivakumar Pdf

During the last few decades, research into natural products has advanced tremendously thanks to contributions from the fields of chemistry, life sciences, food science and material sciences. Comparisons of natural products from microorganisms, lower eukaryotes, animals, higher plants and marine organisms are now well documented. This book provides an easy-to-read overview of natural products. It includes twelve chapters covering most of the aspects of natural products chemistry. Each chapter covers general introduction, nomenclature, occurrence, isolation, detection, structure elucidation both by degradation and spectroscopic techniques, biosynthesis, synthesis, biological activity and commercial applications, if any, of the compounds mentioned in each topic. Therefore it will be useful for students, other researchers and industry. The introduction to each chapter is brief and attempts only to supply general knowledge in the particular field. Furthermore, at the end of each chapter there is a list of recommended books for additional study and a list of relevant questions for practice.

Author : Alexandros L. Zografos
Publisher : John Wiley & Sons
Page : 585 pages
File Size : 45,7 Mb
Release : 2016-04-18
Category : Science
ISBN : 9781118751732

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From Biosynthesis to Total Synthesis by Alexandros L. Zografos Pdf

Focusing on biosynthesis, this book provides readers with approaches and methodologies for modern organic synthesis. By discussing major biosynthetic pathways and their chemical reactions, transformations, and natural products applications; it links biosynthetic mechanisms and more efficient total synthesis. • Describes four major biosynthetic pathways (acetate, mevalonate, shikimic acid, and mixed pathways and alkaloids) and their related mechanisms • Covers reactions, tactics, and strategies for chemical transformations, linking biosynthetic processes and total synthesis • Includes strategies for optimal synthetic plans and introduces a modern molecular approach to natural product synthesis and applications • Acts as a key reference for industry and academic readers looking to advance knowledge in classical total synthesis, organic synthesis, and future directions in the field

Author : Olivier Piva
Publisher : John Wiley & Sons
Page : 314 pages
File Size : 53,8 Mb
Release : 2019-12-12
Category : Science
ISBN : 9781786303493

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Retrosynthetic Analysis and Synthesis of Natural Products 1 by Olivier Piva Pdf

For chemists, attempting to mimic nature by synthesizing complex natural products from raw material is a challenge that is fraught with pitfalls. To tackle this unique but potentially rewarding task, researchers can rely on well-established reactions and methods of practice, or apply their own synthesis methods to verify their potential. Whatever the goal and its complexity, there are multiple ways of achieving it. We must now establish a strategic and effective plan that requires the minimum number of steps, but lends itself to widespread use. This book is structured around the study of a dozen target products (butyrolactone, macrolide, indole compound, cyclobutanic terpene, spiro- and polycyclic derivatives, etc.). For each product, the different disconnections are presented and the associated syntheses are analyzed step by step. The key reactions are described explicitly, followed by diagrams showing the range of impact of certain transformations. This set of data alone is conducive to understanding syntheses and indulging in this difficult, but worthwhile activity.

Author : Armen M. Boldi
Publisher : CRC Press
Page : 363 pages
File Size : 47,6 Mb
Release : 2006-05-16
Category : Science
ISBN : 9781420009279

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Combinatorial Synthesis of Natural Product-Based Libraries by Armen M. Boldi Pdf

Traditionally, the search for new compounds from natural products has been a time- and resource-intensive process. The recent application of combinatorial methods and high-throughput synthesis has allowed scientists to generate a range of new molecular structures from natural products and observe how they interact with biological targets. Combinato

Author : Vasyl Andrushko,Natalia Andrushko
Publisher : John Wiley & Sons
Page : 1836 pages
File Size : 52,5 Mb
Release : 2013-08-16
Category : Science
ISBN : 9781118628331

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Stereoselective Synthesis of Drugs and Natural Products by Vasyl Andrushko,Natalia Andrushko Pdf

Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.

Author : Sunil Kumar Talapatra,Bani Talapatra
Publisher : Springer
Page : 1180 pages
File Size : 51,8 Mb
Release : 2015-03-05
Category : Science
ISBN : 9783642454103

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Chemistry of Plant Natural Products by Sunil Kumar Talapatra,Bani Talapatra Pdf

Aimed at advanced undergraduate and graduate students and researchers working with natural products, Professors Sunil and Bani Talapatra provide a highly accessible compilation describing all aspects of plant natural products. Beginning with a general introduction to set the context, the authors then go on to carefully detail nomenclature, occurrence, isolation, detection, structure elucidation (by both degradation and spectroscopic techniques) stereochemistry, conformation, synthesis, biosynthesis, biological activity and commercial applications of the most important natural products of plant origin. Each chapter also includes detailed references (with titles) and a list of recommended books for additional study making this outstanding treatise a useful resource for teachers of chemistry and researchers working in universities, research institutes and industry.

Author : Koji Nakanishi,Toshio Goto,Shô Itô
Publisher : Academic Press
Page : 573 pages
File Size : 40,6 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483218861

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Natural Products Chemistry by Koji Nakanishi,Toshio Goto,Shô Itô Pdf

Natural Products Chemistry, Volume 1 covers the introductory survey, history, structure, synthesis, reactions, and biosynthesis of natural products. The book discusses the classification of natural products; physico-chemical data on natural products; and the mono- and sesquiterpenes. The text also describes the structure and biosynthesis of sester-, tri- and higher terpenoids, as well as of the steroids. Chemists, biochemists, and microbiologists will find the book invaluable.