New Advances On Zika Virus Research

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New Advances on Zika Virus Research

Author : Luis Martinez-Sobrido,Fernando Almazan Toral
Publisher : MDPI
Page : 554 pages
File Size : 47,9 Mb
Release : 2019-04-02
Category : Arctic medicine. Tropical medicine
ISBN : 9783038977643

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New Advances on Zika Virus Research by Luis Martinez-Sobrido,Fernando Almazan Toral Pdf

Zika virus (ZIKV) is a mosquito-borne member of the Flaviviridae family that historically has been associated with mild febrile illness. However, the recent outbreaks in Brazil in 2015 and its rapid spread throughout South and Central America and the Caribbean, together with its association with severe neurological disorders—including fetal microcephaly and Guillain-Barré syndrome in adults—have changed the historic perspective of ZIKV. Currently, ZIKV is considered an important public health concern that has the potential to affect millions of people worldwide. The significance of ZIKV in human health and the lack of approved vaccines and/or antiviral drugs to combat ZIKV infection have triggered a global effort to develop effective countermeasures to prevent and/or treat ZIKV infection. In this Special Issue of Viruses, we have assembled a collection of 32 research and review articles that cover the more recent advances on ZIKV molecular biology, replication and transmission, virus–host interactions, pathogenesis, epidemiology, vaccine development, antivirals, and viral diagnosis.

Current Concepts in Zika Research

Author : Alfonso J. Rodriguez-Morales
Publisher : BoD – Books on Demand
Page : 131 pages
File Size : 44,8 Mb
Release : 2021-02-10
Category : Science
ISBN : 9781838808754

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Current Concepts in Zika Research by Alfonso J. Rodriguez-Morales Pdf

Zika is an arboviral disease that has caused a significant impact, especially in the Americas after the epidemics in 2015 and 2016. The World Health Organization (WHO) declared it as a Public Health Emergency of International Concern (PHEIC) in 2016, linking it with the Guillain-Barré syndrome and especially the microcephaly and the Congenital Zika Syndrome. The multiple consequences, especially in the central and peripheral nervous system in the short and long term, are still to be better defined. Therefore research on Zika is crucial. This book presents an update of the significant epidemiological and clinical research of Zika over the last years in many aspects and from a multinational perspective.

Dengue and Zika: Control and Antiviral Treatment Strategies

Author : Rolf Hilgenfeld,Subhash G. Vasudevan
Publisher : Springer
Page : 0 pages
File Size : 48,6 Mb
Release : 2018-06-14
Category : Medical
ISBN : 9811087261

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Dengue and Zika: Control and Antiviral Treatment Strategies by Rolf Hilgenfeld,Subhash G. Vasudevan Pdf

This contributed volume contains 25 chapters from leading international scientists working on dengue and Zika viruses, who came together in Praia do Tofo in Mozambique to discuss the latest developments in the fields of epidemiology, pathogenesis, structural virology, immunology, antiviral drug discovery and development, vaccine efficacy, and mosquito control programs. The meeting venue offered an opportunity to discuss current research on these flaviviruses in an idyllic setting, and also to develop first-hand appreciation of the issues in infectious diseases facing developing countries and of the research gaps in Africa. For readers, who should include basic and clinical researchers in the field and public health professionals, the chapters are organized to provide a comprehensive overview of the various topics in current dengue and Zika virus research. A unique feature of the proceedings of this meeting is the inclusion of the discussions that took place following presentations. These have been transcribed and appended to the end of the relevant chapters, and they form the “salt in the soup” of this book.

Zika Virus

Author : Gary Kobinger,Trina Racine
Publisher : Unknown
Page : 290 pages
File Size : 49,7 Mb
Release : 2020
Category : Communicable diseases
ISBN : 107160581X

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Zika Virus by Gary Kobinger,Trina Racine Pdf

This volume discusses the latest protocols used by scientists to understand ZIKV and how to mitigate its presence. These studies will benefit in the detection, diagnosis, management, treatment, and prevention of this infection. The chapters in this book cover techniques in virus isolation, purification, and ways to titrate the virus; recent advancements made in the development of modified molecular techniques; and a discussion on Zika virus itself to help readers better understand this pathogen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Zika Virus: Methods and Protocols is a valuable resource for both novice and expert scientists interested in learning more about this important topic.

Zika Virus: What Have We Learnt Since the Start of the Recent Epidemic?

Author : Rubén Bueno-Marí, Juan-Carlos Saiz,Óscar D. Salomón, Luis C. Villamil-Jiménez,Jorg Heukelbach,Carlos H. Alencar,Paul Armstrong,Paulo Henrique Rosado-de-Castro,Pedro M. Pimentel-Coelho
Publisher : Frontiers Media SA
Page : 253 pages
File Size : 41,5 Mb
Release : 2018-04-12
Category : Electronic
ISBN : 9782889454808

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Zika Virus: What Have We Learnt Since the Start of the Recent Epidemic? by Rubén Bueno-Marí, Juan-Carlos Saiz,Óscar D. Salomón, Luis C. Villamil-Jiménez,Jorg Heukelbach,Carlos H. Alencar,Paul Armstrong,Paulo Henrique Rosado-de-Castro,Pedro M. Pimentel-Coelho Pdf

The considerable number of viral infectious disease threats that have emerged since the beginning of the 21st century have shown the need to dispose global and coordinated responses to fight properly and efficiently against them. Severe acute respiratory syndrome (2003), avian influenza in humans (2005), A(H1N1) pandemic influenza (2009), Middle East respiratory syndrome coronavirus (MERS-CoV) (2012 onward) and Ebola virus disease (2014-2015) are some of the most important examples. The latest emerging and devastating threat was Zika virus, an arbovirus that provoked more than 500,000 suspicious cases in the Americas in 2016 and notable processes of social and medical alarms due to the evidence of a causal link between Zika virus and several congenital injuries, like microcephaly, as well as due to its association with neurological disorders such as Guillain-Barré syndrome in adults (PAHO, 2017). In the framework of this global response and multistrategic approach, the purpose of this Research Topic is to provide updated information and novel researches about control strategies, encompassing virological, entomological and epidemiological data, in order to reach the triad of protagonists of transmission cycles (virus, mosquitoes and humans).

Zika Virus and Host Interactions

Author : Tom Hobman,Anil Kumar,Daniel Limonta
Publisher : Unknown
Page : 256 pages
File Size : 55,6 Mb
Release : 2021
Category : Electronic
ISBN : 3039439502

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Zika Virus and Host Interactions by Tom Hobman,Anil Kumar,Daniel Limonta Pdf

Zika virus (ZIKV), one of the flavivirus family members transmitted by mosquitos, was declared a Public Health Emergency of International Concern by the WHO in February 2016 because of clusters of newborn microcephaly cases and other neurological disorders in Brazil. Most ZIKV infections result in a self-limited flu-like febrile disease, however, if contracted during pregnancy, the virus can also infect fetuses and cause a spectrum of birth defects known as congenital Zika syndrome. To date, no vaccines or antiviral drugs are licensed for ZIKV, and the virus has spread and become endemic to many tropical and sub-tropical countries. Included in this book are thirteen reports addressing diverse aspects of ZIKV-host interactions. These studies range from basic science to clinical research. It is expected that findings from these studies will contribute to a better understanding of the host cells interacting with ZIKV, and may serve as the basis for new diagnostics, antiviral therapies, and vaccine design.

Public Health Communication Interventions

Author : Nurit Guttman
Publisher : SAGE
Page : 305 pages
File Size : 52,5 Mb
Release : 2000-04-15
Category : Language Arts & Disciplines
ISBN : 9780761902607

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Public Health Communication Interventions by Nurit Guttman Pdf

The ethical dimensions of health communicators' interventions and campaigns are brought into question in this thought-provoking book. Examining the efforts to effect behavior change, the author questions how far health communication can and should go in changing people's values. The author broadens the current analysis of interventions and presents conceptual frameworks that help identify values and justifications that are embedded in health communication goals, strategies, and evaluation criteria. This critical approach helps explain how and why choices are made in design and implementation, and provides constructs and frameworks to examine them. It also widens the criteria for program evaluation and policymaking, and provides practitioners, planners, policy-makers, researchers, and students with practice-oriented questions.

Zika Virus Impact, Diagnosis, Control, and Models

Author : Colin R Martin,Caroline Hollins-Martin,Victor R Preedy,Rajkumar Rajendram
Publisher : Academic Press
Page : 510 pages
File Size : 43,7 Mb
Release : 2021-07-04
Category : Medical
ISBN : 9780323903097

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Zika Virus Impact, Diagnosis, Control, and Models by Colin R Martin,Caroline Hollins-Martin,Victor R Preedy,Rajkumar Rajendram Pdf

Zika Virus Impact, Diagnosis, Control, and Models: Volume Two: The Neuroscience of Zika examines diagnosis, vaccines, and potential therapy methods for Zika virus syndrome. The book also details the neuroscience of Guillain-Barré syndrome, its effects and neuromuscular rehabilitation. It is designed to help readers better understand detection, therapies for Zika virus, preventative vaccines, diagnosis and associated microcephaly. Chapters on models enable further research and understanding. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions. Provides a broad range of topics related to the neuroscience of Zika, including its diagnosis, vaccines and therapy Contains chapter abstracts, key facts, a dictionary of terms and summary points to aid in understanding Discusses novel and non-pharmacological therapies, Guillain-Barré Syndrome and vaccine development Features chapters on rat, mouse, and guinea pig models of Zika and case reports of Zika co-infection with chikungunya, dengue-2 and Guillain-Barré Includes coverage of microcephaly and developmental delays and examines Zika outbreaks in Brazil, Honduras, Uganda, Jamaica and Mozambique

Human Viruses: Diseases, Treatments and Vaccines

Author : Shamim I. Ahmad
Publisher : Springer Nature
Page : 745 pages
File Size : 50,5 Mb
Release : 2021-05-19
Category : Medical
ISBN : 9783030711658

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Human Viruses: Diseases, Treatments and Vaccines by Shamim I. Ahmad Pdf

This book discusses current evidence on human viruses and provides an extensive coverage of newly emerged viruses and current strategies for treatment. Offering a new perspective in view of the re-emergence of Ebola in African countries and Dengue in India and Pakistan, the contents include chapters on emergence, pathogenicity, epidemiology and vaccine uptake. Human Viruses: Diseases, Treatments and Vaccines: The New Insights discusses a range of viruses from the most common such as Influenza and Hepatitis to Zika, Poliomyelitis and Chikungunya among many others. It is authored by a team of experts on viral disease and will be of immense use to virologists, public health experts and clinicians.

ZIKA VIRUS DISEASE

Author : Adnan Quereshi
Publisher : Academic Press
Page : 180 pages
File Size : 54,7 Mb
Release : 2017-11-17
Category : Science
ISBN : 9780128125472

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ZIKA VIRUS DISEASE by Adnan Quereshi Pdf

Zika Virus provides an authoritative account of one of most fascinating viruses of the 21st century, covering all the main points. It includes coverage of clinical manifestations, such as fever and fatigue, but also delves into neurological manifestations like acute demyelinating neuropathy. In addition, the book discusses new evidence that suggests that Zika fever in pregnant women can cause abnormal brain development in fetuses by mother-to-child transmission. The Zika virus infection has become one of the first where women are actively discouraged from getting pregnant. Readers will find this book to be a comprehensive resource on the topic. Covers every important aspect of the Zika virus disease, from biological, to social and economic impacts Focuses on women’s health issues that have surfaced, including birth defects in newborns Written in an easy to comprehend manner, with technical terms clearly defined in chapters that highlight genetics

Japanese Encephalitis and West Nile Viruses

Author : John Mackenzie,A.D.T. Barrett,V. Deubel
Publisher : Springer Science & Business Media
Page : 423 pages
File Size : 45,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642594038

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Japanese Encephalitis and West Nile Viruses by John Mackenzie,A.D.T. Barrett,V. Deubel Pdf

Japanese encephalitis and West Nile viruses are members of the Japanese encephalitis serological group of the genus Flavivirus and therefore closely related genetically and antigenically. They share a number of properties, including the use of birds as their major wildlife maintenance host and Culicine mosquitoes for transmission, and they are both associated with severe human disease, as well as fatal infections in horses. The emergence of these two viruses, and their well-established propensity to colonise new areas, make it timely to re-examine their ecology, biology, molecular structure, replication and epidemiology, and these therefore provide the focus of this volume.

Tropical Dermatology E-Book

Author : Steven K Tyring,Omar Lupi,Ulrich R Hengge
Publisher : Elsevier Health Sciences
Page : 421 pages
File Size : 48,8 Mb
Release : 2016-10-17
Category : Medical
ISBN : 9780323339148

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Tropical Dermatology E-Book by Steven K Tyring,Omar Lupi,Ulrich R Hengge Pdf

In an increasingly global community, the rapid adaptation of microorganisms has facilitated the return of old communicable diseases and the emergence of new ones. Tropical Dermatology, 2nd Edition, provides a practical, highly illustrated approach to the diagnosis and treatment of a wide range of tropical skin diseases. In a concise and user-friendly format, it offers authoritative coverage of epidemiology, diagnosis, differential diagnosis, pathology, laboratory tests, management, and prevention for both common and rare conditions. Examines the full range of tropical skin diseases in an easy-to-reference format, with consistently organized, templated chapters. Structures clinical guidance by disease rather than by microbe or "bug." Covers the key issues for travelers, important considerations for people working in the tropics, and non-infectious conditions. Provides authoritative guidance for dermatologists, infectious disease specialists, and travel medicine physicians. Includes new chapters on Tungiasis, Ebola and Zika virus. Features updates on emerging diseases and new therapies throughout. Includes brand-new, "hard-to-find" clinical images, for a total of more than 650 full-color illustrations throughout. Integrates the knowledge and experience of new international contributors, including recognized experts in dermatology from the United States, Europe, South America, Africa, and Asia.

Comprehensive Guidelines for Prevention and Control of Dengue and Dengue Haemorrhagic Fever

Author : WHO Regional Office for South-East Asia
Publisher : World Health Organization
Page : 0 pages
File Size : 46,6 Mb
Release : 2011
Category : Medical
ISBN : 9290223944

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Comprehensive Guidelines for Prevention and Control of Dengue and Dengue Haemorrhagic Fever by WHO Regional Office for South-East Asia Pdf

Dengue Fever is the fastest emerging arboviral infection with major public health consequences for millions of people around the world, and in particular the South-East Asia region. These regional guidelines were extensively revised, updated and expanded with the focus on new and additional topics of current relevance to the populations of the region. They are intended to provide guidance to national and local-level program managers and public health officials, as well as stakeholders, including health practitioners, laboratory personnel and multisectoral partners, in strategic planning, implementation, monitoring and evaluation, and strengthening the response to dengue prevention and control in their countries. Scientists and researchers involved in vaccine and antiviral drug development will also find crucial baseline information in this publication.

Dengue

Author : World Health Organization
Publisher : World Health Organization
Page : 159 pages
File Size : 47,9 Mb
Release : 2009
Category : Medical
ISBN : 9789241547871

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Dengue by World Health Organization Pdf

This publication is intended to contribute to prevention and control of the morbidity and mortality associated with dengue and to serve as an authoritative reference source for health workers and researchers. These guidelines are not intended to replace national guidelines but to assist in the development of national or regional guidelines. They are expected to remain valid for five years (until 2014), although developments in research could change their validity.--Publisher's description.

Gadd45 Stress Sensor Genes

Author : Dan A. Liebermann,Barbara Hoffman
Publisher : Springer Science & Business Media
Page : 141 pages
File Size : 49,6 Mb
Release : 2013-10-08
Category : Medical
ISBN : 9781461482895

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Gadd45 Stress Sensor Genes by Dan A. Liebermann,Barbara Hoffman Pdf

Emerging evidence indicates that the Gadd45 family of genes play a unique and critical role as sensors of stress, including genotoxic, physiological and oncogenic stress. The stress response Gadd45 family of genes (Gadd45a, Gadd45b & Gadd45g), discovered by Dr. Liebermann and other researchers, encode for small (18 kd) nuclear/cytoplasmic proteins). These genes are rapidly induced by a wide variety of endogenous and exogenous stress stimuli. In spite of marked similarities, Gadd45 genes are regulated differently & exhibit functional diversity. Gadd45 are implicated in cell cycle arrest, DNA demethylation & repair, apoptosis, cell survival, genomic stability, inflammation, & in response to physiological and oncogenic stress. Functions of Gadd45 genes are mediated by protein-protein interactions that modulate structure/function of other cellular proteins implicated in cell cycle regulation and the response of cells to stress; these interactions vary depending upon the biological setting including cell type, developmental stage and stress/stimulus. Protein partners include cdc2/cyclinB1, p21, the p38/JNK stress induced kinase pathways, and PCNA/histones. The purpose of this book is to provide a comprehensive picture of the unique global role Gadd45 genes play as stress sensors & the molecular pathways involved.