New Insights Into Autoinflammatory Diseases From Bench To Bedside

Author : Katerina Laskari,Riccardo Papa,Paul Van Daele,Elena Tsitsamis,Wafa Ammouri,Anastasios E. Germenis,Carla Gaggiano,Sinisa Savic
Publisher : Frontiers Media SA
Page : 137 pages
File Size : 45,5 Mb
Release : 2023-10-18
Category : Medical
ISBN : 9782832536131

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New Insights into Autoinflammatory Diseases: From Bench to Bedside by Katerina Laskari,Riccardo Papa,Paul Van Daele,Elena Tsitsamis,Wafa Ammouri,Anastasios E. Germenis,Carla Gaggiano,Sinisa Savic Pdf

Systemic autoinflammatory diseases (SAIDs) are a growing group of rare disorders caused by dysregulation of the innate immune system leading to episodes of organ-specific and systemic inflammation. Autoinflammation as a distinct disease category was first reported in 1999 as a group of monogenic disorders with resultant activation of the inflammasome and cytokine excess, presenting as periodic fever and inflammation in serous membranes. Since this original description, the focus has shifted considerably to the inclusion of complex multifactorial conditions, and more than 30 associated genes have been identified. Disease severity varies from mild to life threatening. Advances in the understanding of the pathogenetic role of interleukin-1, have opened new promising horizons in the treatment of these patients, and significantly altered disease outcome.

Author : Anonim
Publisher : ScholarlyEditions
Page : 553 pages
File Size : 42,7 Mb
Release : 2013-07-22
Category : Medical
ISBN : 9781481650878

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Autoimmune Diseases: New Insights for the Healthcare Professional: 2013 Edition by Anonim Pdf

Autoimmune Diseases: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Genetics. The editors have built Autoimmune Diseases: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Genetics in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Autoimmune Diseases: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Anonim
Publisher : ScholarlyEditions
Page : 124 pages
File Size : 45,7 Mb
Release : 2012-12-10
Category : Medical
ISBN : 9781464971877

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Liver Diseases: New Insights for the Healthcare Professional: 2012 Edition by Anonim Pdf

Liver Diseases: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Liver Diseases. The editors have built Liver Diseases: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Liver Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Liver Diseases: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Anonim
Publisher : ScholarlyEditions
Page : 156 pages
File Size : 51,7 Mb
Release : 2012-12-10
Category : Medical
ISBN : 9781464971297

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Autoimmune Diseases: New Insights for the Healthcare Professional: 2012 Edition by Anonim Pdf

Autoimmune Diseases: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Autoimmune Diseases. The editors have built Autoimmune Diseases: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Autoimmune Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Autoimmune Diseases: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Paulus Stefan Rommer,Martin S. Weber,Zsolt Illes,Uwe K. Zettl
Publisher : Frontiers Media SA
Page : 253 pages
File Size : 50,5 Mb
Release : 2020-03-13
Category : Electronic
ISBN : 9782889635665

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Multiple Sclerosis – From Bench to Bedside: Currents Insights into Pathophysiological Concepts and Their Potential Impact on Patients by Paulus Stefan Rommer,Martin S. Weber,Zsolt Illes,Uwe K. Zettl Pdf

Author : Nima Rezaei
Publisher : Academic Press
Page : 700 pages
File Size : 44,6 Mb
Release : 2022-08-16
Category : Medical
ISBN : 9780128180075

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Clinical Immunology by Nima Rezaei Pdf

Clinical Immunology not only introduces the reader to the human immune system, it also covers immunology from clinical manifestation to therapeutic approaches in a wide range of conditions. Each chapter describes an introduction, the clinical manifestations, the immunopathogenesis, diagnosis, lab tests and therapeutic approaches. The book guides clinicians, researchers and students to a better understanding of the matters of immunologic-based diseases that can lead to better decision-making for patients.Because of the growing knowledge regarding the function of immune system in health and disease conditions, clinicians, researchers and students increasingly require an exclusive scientific reference to guide them on matters of immunologic-based diseases. Accordingly, despite the existence of numerous high quality references in basic and cellular/molecular immunology which deeply explain different immunologic mechanisms, there is still a knowledge gap in the field of clinical immunology. Provides essentials, updates clinical knowledge regarding immune system diseases, and cover different aspects of clinical immunology, from immunopathogenesis and etiology to diagnosis and treatment Introduces the most advanced approaches and laboratory tests as well as their interpretation in the diagnosis of immune system disorders Focuses on the practical use of clinical immunology, from bedside to bench and vice versa

Author : Anonim
Publisher : ScholarlyEditions
Page : 185 pages
File Size : 42,9 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464901256

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Multiple Sclerosis: New Insights for the Healthcare Professional: 2011 Edition by Anonim Pdf

Multiple Sclerosis: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Multiple Sclerosis. The editors have built Multiple Sclerosis: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Multiple Sclerosis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Multiple Sclerosis: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Walter Gottlieb Land
Publisher : Springer Nature
Page : 708 pages
File Size : 54,9 Mb
Release : 2023-03-10
Category : Medical
ISBN : 9783031217760

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Damage-Associated Molecular Patterns in Human Diseases by Walter Gottlieb Land Pdf

The core of this three-volume book deals with damage-associated molecular patterns abbreviated “DAMPs”, which are unique molecules that save life and fight for survival of all organisms on this planet by triggering robust inflammatory/immune defense responses upon any injury, including those caused by pathogens such as viruses and bacteria. However, these molecules also have a dark side: when produced in excess upon severe insults, they can trigger serious human diseases. The three volumes present current understanding of the importance of DAMP-promoted immune responses in the etiopathogenesis of human diseases and explore how this understanding is impacting diagnosis, prognosis, and future treatment. This third volume addresses the potential of DAMPs in clinical practice, as therapeutic targets and therapeutics, by focusing on a description of antigen-related diseases, which are pathogenetically dominated by DAMPs, that is, infectious and autoimmune disorders and allograft rejection (as an undesired function of these molecules), as well as tumor rejection (as the desired function of these molecules). The book is written for professionals from all medical and paramedical disciplines who are interested in the introduction of innovative data from modern inflammation and immunity research into clinical practice. In this sense, the book reflects an approach to translational medicine. The readership will include all practitioners and clinicians, in particular, ICU clinicians, infectiologists, microbiologists, virologists, hematologists, rheumatologists, diabetologists, neurologists, transplantologists, oncologists, and pharmacists. Also available: Damage-Associated Molecular Patterns in Human Diseases - Vol. 1: Injury-Induced Innate Immune Responses; Damage-Associated Molecular Patterns in Human Diseases - Vol. 2: Danger Signals as Diagnostics, Prognostics, and Therapeutic Targets.

Author : Anonim
Publisher : ScholarlyEditions
Page : 121 pages
File Size : 47,6 Mb
Release : 2013-07-22
Category : Medical
ISBN : 9781481660464

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Motor Neuron Disease: New Insights for the Healthcare Professional: 2013 Edition by Anonim Pdf

Motor Neuron Disease: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Diagnosis and Screening in a concise format. The editors have built Motor Neuron Disease: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Motor Neuron Disease: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Anonim
Publisher : ScholarlyEditions
Page : 112 pages
File Size : 50,7 Mb
Release : 2012-12-10
Category : Medical
ISBN : 9781464972072

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Psoriasis: New Insights for the Healthcare Professional: 2012 Edition by Anonim Pdf

Psoriasis: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Psoriasis. The editors have built Psoriasis: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Psoriasis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Psoriasis: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Hao Wang,Caigan Du
Publisher : Frontiers Media SA
Page : 194 pages
File Size : 43,7 Mb
Release : 2022-03-09
Category : Science
ISBN : 9782889744084

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New Insights into and Interventions of the Persistent Immune Responses in Chronic Graft Rejection, 2nd Edition by Hao Wang,Caigan Du Pdf

Publisher’s note: This is a 2nd edition due to an article retraction.

Author : Nima Rezaei
Publisher : Elsevier
Page : 630 pages
File Size : 50,5 Mb
Release : 2023-02-20
Category : Medical
ISBN : 9780323984546

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Translational Autoimmunity, Volume 6 by Nima Rezaei Pdf

Translational Autoimmunity: Advances in Autoimmune Rheumatic Diseases, Volume Six addresses autoimmune diseases classified under the category of rheumatic diseases. Rheumatic diseases are heterogeneous groups of disorders in which inflammation affects not only joints, but also tendons, ligaments and bones. This updated release focuses on immunopathogenesis and clinical and laboratory details of rheumatic diseases, including rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, osteoarthritis and Sjogren’s syndrome, and will be of interest to researchers, students and clinicians interested in autoimmune diseases, especially rheumatic diseases. From an introduction to rheumatic diseases to diagnostic laboratory tests, and from the microbiota-immunity to cell-based therapies, the bench to bedside approach to rheumatic diseases is the main subject of discussion in this comprehensive resource. Gives an introduction on rheumatic diseases, from bench to bedside Describes diagnostic laboratory tests in rheumatic diseases Meets the needs of basic scientists, clinicians and translational scientists and industry partners Focuses on immunopathogenesis and clinical and laboratory details of rheumatic diseases

Author : R. Duchmann
Publisher : Springer Science & Business Media
Page : 246 pages
File Size : 49,8 Mb
Release : 2004-04-30
Category : Medical
ISBN : 0792387872

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Mechanisms of Intestinal Inflammation by R. Duchmann Pdf

In recent years considerable progress has been achieved in regard to our understanding of the induction and modulation of the immune response in the intestinal mucosa. It is clear that this mucosal immune reaction is predominantly steered by certain T-cell populations, which are characterized by their cytokine secretion profile. Less well known are the conditions under which the uptake and processing of a specific antigen leads to a certain immune response, whether it be protective, tolerant or inflammatory. However, here again distinct progress has been made in our understanding. Equally significant for immune regulation in the gut appears to be so-called innate immunity. Every shift of equilibrium in the highly regulated mucosal immune reaction is accompanied by an inflammatory reaction and destruction of the mucosa. In nearly all cases, this inflammatory response is dependent on the presence of bacterial intestinal flora. This book, the proceedings of Falk Symposium 133 on Mechanisms of Intestinal Inflammation: Implications for Therapeutic Intervention in IBD', held in Berlin, Germany, on 10-11 June 2003, summarizes present knowledge in the area of unspecific and specific immune reactions in the gut, recording the gaps in our knowledge and, in particular, presenting the possibilities of targeted intervention. The link to inflammatory bowel diseases - Crohn's disease and ulcerative colitis - is always in focus. Chapters by an international panel of basic scientists, clinical researchers and clinicians also record the problems which can originate through today's possible modulation of the immune reaction, setting the basis for review of clinical problems. This book is valuable readings for all scientists and physicians, who, from different perspectives, have an interest in research on IBD and in the clinical management of these diseases.

Author : Xiao-Kang Li,Ye Htun Oo
Publisher : Frontiers Media SA
Page : 239 pages
File Size : 40,5 Mb
Release : 2021-11-24
Category : Medical
ISBN : 9782889716623

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New Insights on Liver Transplant and Tolerance by Xiao-Kang Li,Ye Htun Oo Pdf

Author : Katja Perdan Pirkmajer,Blaž Burja,Katja Lakota
Publisher : BoD – Books on Demand
Page : 132 pages
File Size : 47,6 Mb
Release : 2024-05-15
Category : Medical
ISBN : 9781837696703

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Systemic Sclerosis - Recent Advances and New Perspectives by Katja Perdan Pirkmajer,Blaž Burja,Katja Lakota Pdf

Systemic sclerosis (SSc) is a multisystem autoimmune disease involving vasculopathy and immune activation that leads to the deposition of extracellular matrix and the development of fibrosis, resulting in cardinal clinical problems. Systemic Sclerosis - Recent Advances and New Perspectives provides a comprehensive overview of the pathophysiology, diagnosis, and specific management of the clinical manifestations of SSc. The book addresses the current understanding of the causes and consequences of inflammatory activation, chromosomal instability, and activating factors. Special emphasis is placed on diagnosis, from the recognition of very early systemic sclerosis and consideration of its treatment to diagnostic methods for microvascular and pulmonary involvement. It also highlights the less life-threatening but very common manifestations of bone and skeletal muscle involvement, which affect patient quality of life.