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New Insights Into The Complexity Of Tumor Immunology In B Cell Malignancies Prognostic And Predictive Biomarkers And Therapy Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of New Insights Into The Complexity Of Tumor Immunology In B Cell Malignancies Prognostic And Predictive Biomarkers And Therapy book. This book definitely worth reading, it is an incredibly well-written.
Author : Jérôme Paggetti,Martina Seiffert,Etienne Moussay
Publisher : Frontiers Media SA
Page : 127 pages
File Size : 43,7 Mb
Release : 2022-06-23
Category : Medical
ISBN : 9782889742073
Author : Jérôme Paggetti,Martina Seiffert,Etienne Moussay
Publisher : Frontiers Media SA
Page : 164 pages
File Size : 49,8 Mb
Release : 2022-01-31
Category : Medical
ISBN : 9782889742417
Author : Jérôme Paggetti,Etienne Moussay,Martina Seiffert
Publisher : Frontiers Media SA
Page : 191 pages
File Size : 55,7 Mb
Release : 2022-03-02
Category : Medical
ISBN : 9782889742066
Topic Editor MS received funding from Bayer AG.
Author : Joseph D. Rosenblatt,Eckhard R. Podack,Glen N. Barber,Augusto Ochoa
Publisher : Springer Science & Business Media
Page : 371 pages
File Size : 45,7 Mb
Release : 2013-10-25
Category : Medical
ISBN : 9781461488095
Recent advances in understanding of fundamental immunology have created new insights into the dynamic interactions between tumors and the immune system. This includes new understanding of T- and B-cell interaction, immune inhibitory mechanisms including the biology of T regulatory cells, myeloid suppressor cells, and dendritic cell subsets. Enhanced understanding of mechanisms underlying T-cell anergy such as arginine deprivation, immunosuppressive cytokines, defective innate and interferon response pathways, and NKG2D downregulation have all provided new insight into suppression of anti-tumor immunity and tumor evasion. In addition to emerging understanding of tumor evasion, new immune targets such as CTLA4 blockade, NK stimulatory receptors, manipulation of the antigen processing and presentation, cytokine and costimulatory responses all provide new possibilities for enhancing anti-tumor immunity even in tumors previously felt to be resistant to immune attack. Several of these strategies have already been realized in the clinic. The volume will explore evolving paradigms in antigen presentation, dendritic cell biology, the innate response and immunosuppressive mechanisms, and emerging strategies for manipulation of the immune system for therapeutic benefit that have realized success in neuroblastoma, leukemia, melanoma, lung cancer, and allogeneic transplantation. Early successes as well as failures will be highlighted to provide a snapshot of the state of clinical immunotherapy with an eye to future possibilities such as combination therapies, adoptive T-cell transfer, and the retargeting of immune cells via T-cell receptor engineering.
Author : Afsheen Raza
Publisher : BoD – Books on Demand
Page : 214 pages
File Size : 41,5 Mb
Release : 2023-03-08
Category : Medical
ISBN : 9781803565903
Immune Checkpoint Inhibitors - New Insights and Recent Progress explores a vast array of subjects related to immune checkpoint inhibitors and presents novel insights in this emerging field. Chapters address such topics as mechanistic approaches of emerging immune checkpoint inhibitors, their role in clinical and pre-clinical trials, the manipulation of the system by immune-related adverse events that hinder the utility of these immune molecules, and the predictive and prognostic aspects of these molecules as biomarkers of response in immunotherapy. The book is useful for students, clinicians, and scientists to gain updated information on managing patients treated with immune checkpoint inhibitors.
Author : Ombretta Melaiu,Silvia Pesce
Publisher : Frontiers Media SA
Page : 171 pages
File Size : 55,8 Mb
Release : 2023-07-21
Category : Medical
ISBN : 9782832529690
Author : Ana Karina de Oliveira,Jay William Fox,Mariane Tami Amano,Adriana Franco Paes Leme,Rodrigo Nalio Ramos
Publisher : Frontiers Media SA
Page : 309 pages
File Size : 42,6 Mb
Release : 2022-09-30
Category : Science
ISBN : 9782832501320
Author : Bo Zhai,Zhendong Jin,Chen Yang,Gang Tian
Publisher : Frontiers Media SA
Page : 261 pages
File Size : 47,7 Mb
Release : 2024-06-04
Category : Medical
ISBN : 9782832549247
The cellular signaling network refers to the complex system formed by the interactions between various signaling molecules and receptors within and between cells. It consists of multiple signaling pathways that mediate intricate cellular interactions both internally and externally. The development of cancer is closely associated with the intricate signaling transduction network within cells, where multiple signaling pathways are interconnected and collectively regulate the biological phenotypes of tumor cells.
Author : Michael Grasso III,Demetrius H. Bagley
Publisher : Springer
Page : 141 pages
File Size : 50,6 Mb
Release : 2015-07-03
Category : Medical
ISBN : 9783319138695
Upper Urinary Tract Urothelial Carcinoma was at one time felt to be a somewhat rare entity. With the success of various treatments for bladder urothelial carcinoma, the incidence of this disease in the uretere and kidney is rising. Many medical subspecialists encounter these complex patients and a multimodality treatment plan is often required for care.
Author : Qian Xiao,Xuejun Sun,Zimu Deng,Jian Cao
Publisher : Frontiers Media SA
Page : 303 pages
File Size : 45,5 Mb
Release : 2023-02-01
Category : Science
ISBN : 9782832513347
Author : Xiangqian Guo,Longxiang Xie,Liuyang Wang,Jing Zhao,Wan Zhu
Publisher : Frontiers Media SA
Page : 297 pages
File Size : 46,9 Mb
Release : 2022-06-16
Category : Science
ISBN : 9782889763832
Author : Mingzhu Yin,Qin Yan,Jian Cao,Bihui Huang
Publisher : Frontiers Media SA
Page : 263 pages
File Size : 53,6 Mb
Release : 2022-05-27
Category : Medical
ISBN : 9782889762460
Author : Marie-Caroline Dieu-Nosjean
Publisher : Humana
Page : 289 pages
File Size : 49,6 Mb
Release : 2019-09-07
Category : Medical
ISBN : 1493993720
This volume explores the various methods used to study tertiary lymphoid structures (TLS) in pathological situations. Pre-clinical models are also discussed in detail to show how TLS structure, development, and maintenance can be targeted and studied in vivo. The chapters in this book cover topics such as humans and mice; strategies to quantify TLS in order to use it in stained tissue sections; classifying a gene signature form fixed and paraffin-embedded tissues; and development of murine inflammatory models to help look at TLS in the context of infection or malignancy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Tertiary Lymphoid Structures: Methods and Protocols is a valuable resource that increases the reader’s knowledge on immune functions and how they will pave the way to future therapeutic applications.
Author : Petros Christopoulos,Udo S. Gaipl
Publisher : Frontiers Media SA
Page : 197 pages
File Size : 50,5 Mb
Release : 2024-06-17
Category : Medical
ISBN : 9782832521946
Author : Vivek Verma,Catherine Sautes-Fridman,Anna Dimberg
Publisher : Frontiers Media SA
Page : 178 pages
File Size : 46,7 Mb
Release : 2022-04-06
Category : Medical
ISBN : 9782889748624
