New Malaria Research

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Malaria Immunology

Peter Perlmann,Marita Troye-Blomberg
Malaria Immunology Book PDF

Author : Peter Perlmann,Marita Troye-Blomberg
Publisher : Karger Medical and Scientific Publishers
Page : 422 pages
File Size : 43,8 Mb
Release : 2002-01-01
Category : Medical
ISBN : 9783805573764

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Malaria Immunology by Peter Perlmann,Marita Troye-Blomberg Pdf

Despite extensive efforts to control it, malaria is still one of the most devastating infectious diseases worldwide. This book, now in its second edition, provides a broad and up-to-date overview of the rapidly expanding field of malaria immunology and its importance in the control of this disease. The first section deals with the malaria parasite and its interactions with both the vertebrate host and the mosquitoes which transmit the disease. In the second part, the mechanisms of immunity and their regulation by environmental and genetic factors are discussed. Finally, this volume contains several chapters on malaria vaccine development, describing the application of the most recent vaccine technologies as well as ongoing and planned vaccine trials. Authored by well-recognized experts, this volume not only demonstrates the rapid progress being made in the search for vaccines against malaria, but also broadens our understanding of immunity to infection in general. It is therefore highly recommended reading for all scientists and professionals in the fields of immunology, infection and vaccine development.

Advances in Malaria Research

Deepak Gaur,Chetan E. Chitnis,Virander S. Chauhan
Advances in Malaria Research Book PDF

Author : Deepak Gaur,Chetan E. Chitnis,Virander S. Chauhan
Publisher : John Wiley & Sons
Page : 611 pages
File Size : 44,9 Mb
Release : 2016-12-27
Category : Science
ISBN : 9781118493793

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Advances in Malaria Research by Deepak Gaur,Chetan E. Chitnis,Virander S. Chauhan Pdf

Thoroughly reviews our current understanding of malarial biology Explores the subject with insights from post-genomic technologies Looks broadly at the disease, vectors of infection, and treatment and prevention strategies A timely publication with chapters written by global researchers leaders

Saving Lives, Buying Time

Institute of Medicine,Board on Global Health,Committee on the Economics of Antimalarial Drugs
Saving Lives Buying Time Book PDF

Author : Institute of Medicine,Board on Global Health,Committee on the Economics of Antimalarial Drugs
Publisher : National Academies Press
Page : 384 pages
File Size : 41,6 Mb
Release : 2004-09-09
Category : Medical
ISBN : 9780309165938

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Saving Lives, Buying Time by Institute of Medicine,Board on Global Health,Committee on the Economics of Antimalarial Drugs Pdf

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.

Malaria

Institute of Medicine,Division of International Health,Committee for the Study on Malaria Prevention and Control
Malaria Book PDF

Author : Institute of Medicine,Division of International Health,Committee for the Study on Malaria Prevention and Control
Publisher : National Academies Press
Page : 312 pages
File Size : 50,5 Mb
Release : 1991-02-01
Category : Medical
ISBN : 0309045274

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Malaria by Institute of Medicine,Division of International Health,Committee for the Study on Malaria Prevention and Control Pdf

Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.

New Malaria Research

Maynard R. Hoche
New Malaria Research Book PDF

Author : Maynard R. Hoche
Publisher : Unknown
Page : 128 pages
File Size : 50,5 Mb
Release : 2012-06-28
Category : Malaria
ISBN : 1604563486

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New Malaria Research by Maynard R. Hoche Pdf

This book is dedicated to recent research advances on malaria which is an infectious disease that is widespread in tropical and subtropical regions. It infects between 300 and 500 million people every year and causes between one and three million deaths annually, mostly among young children in Sub-Saharan Africa. Malaria is not just a disease commonly associated with poverty, but is also a cause of poverty and a major hindrance to economic development. Malaria is one of the most common infectious diseases and an enormous public-health problem. The disease is caused by protozoan parasites of the genus Plasmodium. The most serious forms of the disease are caused by Plasmodium falciparum and Plasmodium vivax, but other related species (Plasmodium ovale and Plasmodium malariae) can also infect humans. This group of human-pathogenic Plasmodium species are usually referred to as malaria parasites. Malaria parasites are transmitted by female Anopheles mosquitoes. The parasites multiply within red blood cells, causing symptoms that include fever, anaemia, chills, flu-like illness, and in severe cases, coma and death. Malaria transmission can be reduced by preventing mosquito bites with mosquito nets and insect repellents or by mosquito control by spraying insecticides inside houses and draining standing water where mosquitoes lay their eggs. One of the most important recent advances in malaria research is the mapping of the Plasmodium falciparum genome. For the next five to ten years, until an effective vaccine is developed, malaria control will largely be dependent on vector control measures such as improvements in housing construction, source reduction, impregnated bed-nets, and residual insecticide treatment.

The Malaria Project

Karen M. Masterson
The Malaria Project Book PDF

Author : Karen M. Masterson
Publisher : Penguin
Page : 384 pages
File Size : 49,6 Mb
Release : 2014-10-07
Category : History
ISBN : 9780698140134

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The Malaria Project by Karen M. Masterson Pdf

A fascinating and shocking historical exposé, The Malaria Project is the story of America's secret mission to combat malaria during World War II—a campaign modeled after a German project which tested experimental drugs on men gone mad from syphilis. American war planners, foreseeing the tactical need for a malaria drug, recreated the German model, then grew it tenfold. Quickly becoming the biggest and most important medical initiative of the war, the project tasked dozens of the country’s top research scientists and university labs to find a treatment to remedy half a million U.S. troops incapacitated by malaria. Spearheading the new U.S. effort was Dr. Lowell T. Coggeshall, the son of a poor Indiana farmer whose persistent drive and curiosity led him to become one of the most innovative thinkers in solving the malaria problem. He recruited private corporations, such as today's Squibb and Eli Lilly, and the nation’s best chemists out of Harvard and Johns Hopkins to make novel compounds that skilled technicians tested on birds. Giants in the field of clinical research, including the future NIH director James Shannon, then tested the drugs on mental health patients and convicted criminals—including infamous murderer Nathan Leopold. By 1943, a dozen strains of malaria brought home in the veins of sick soldiers were injected into these human guinea pigs for drug studies. After hundreds of trials and many deaths, they found their “magic bullet,” but not in a U.S. laboratory. America 's best weapon against malaria, still used today, was captured in battle from the Nazis. Called chloroquine, it went on to save more lives than any other drug in history. Karen M. Masterson, a journalist turned malaria researcher, uncovers the complete story behind this dark tale of science, medicine and war. Illuminating, riveting and surprising, The Malaria Project captures the ethical perils of seeking treatments for disease while ignoring the human condition.

Fighting Malaria

Inmaculada Peñas Jiménez,Andreas Holtel
Fighting Malaria Book PDF

Author : Inmaculada Peñas Jiménez,Andreas Holtel
Publisher : Office for Official Publications of the European Communities
Page : 16 pages
File Size : 54,7 Mb
Release : 2011
Category : Malaria
ISBN : MINN:31951D03160999F

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Fighting Malaria by Inmaculada Peñas Jiménez,Andreas Holtel Pdf

"Malaria is an old infectious disease that still kills nearly one million people every year, mostly children and women in developing countries. While in certain geographical areas malaria control has been remarkable, thanks to insecticide-treated bed nets and effective treatment; the development of resistances to insecticides, to medicines and the quality of the health systems in these regions are threats that demand increased research efforts. Europe has been traditionally strong in malaria research. More recently, targeted and sustained support for malaria research at EU level, through the 6th and 7th Framework Programmes for research and technological development (FP6 (2002-2006) and FP7 (2007-2013)), has contributed to better structure the malaria research, under complementary research projects and networks, around few key areas: fundamental research on the malaria parasite, development of new drugs, research and development of a vaccine, research to control the malaria-transmitting mosquito vector, research for better diagnostic tests and operational research for better control intervention tools and strategies. Considerable efforts are being undertaken to ensure adequate participation of research groups from endemic countries, in particular from Africa, aiming at strengthen research capacities in these countries."--P. [4] of cover.

Malaria: New Insights for the Healthcare Professional: 2011 Edition

Anonim
Malaria New Insights for the Healthcare Professional 2011 Edition Book PDF

Author : Anonim
Publisher : ScholarlyEditions
Page : 161 pages
File Size : 41,8 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464902543

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Malaria: New Insights for the Healthcare Professional: 2011 Edition by Anonim Pdf

Malaria: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Malaria. The editors have built Malaria: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Malaria in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Malaria: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

CDC Yellow Book 2018: Health Information for International Travel

Centers for Disease Control and Prevention CDC
CDC Yellow Book 2018 Health Information for International Travel Book PDF

Author : Centers for Disease Control and Prevention CDC
Publisher : Oxford University Press
Page : 672 pages
File Size : 45,9 Mb
Release : 2017-04-17
Category : Medical
ISBN : 9780190628635

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CDC Yellow Book 2018: Health Information for International Travel by Centers for Disease Control and Prevention CDC Pdf

THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Artemisinin-Based and Other Antimalarials

Guoqiao Li,Ying Li,Zelin Li,Meiyi Zeng
Artemisinin Based and Other Antimalarials Book PDF

Author : Guoqiao Li,Ying Li,Zelin Li,Meiyi Zeng
Publisher : Academic Press
Page : 736 pages
File Size : 55,5 Mb
Release : 2017-11-28
Category : Medical
ISBN : 9780128132111

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Artemisinin-Based and Other Antimalarials by Guoqiao Li,Ying Li,Zelin Li,Meiyi Zeng Pdf

Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery

Disease Control Priorities, Third Edition (Volume 6)

King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Disease Control Priorities Third Edition Volume 6 Book PDF

Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 42,5 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257

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Disease Control Priorities, Third Edition (Volume 6) by King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha Pdf

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Global Technical Strategy for Malaria 2016-2030

World Health Organization
Global Technical Strategy for Malaria 2016 2030 Book PDF

Author : World Health Organization
Publisher : World Health Organization
Page : 35 pages
File Size : 48,9 Mb
Release : 2015-11-04
Category : Medical
ISBN : 9789241564991

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Global Technical Strategy for Malaria 2016-2030 by World Health Organization Pdf

The World Health Organization's Global Technical Strategy for Malaria 2016- 2030 has been developed with the aim to help countries to reduce the human suffering caused by the world's deadliest mosquito-borne disease. Adopted by the World Health Assembly in May 2015 it provides comprehensive technical guidance to countries and development partners for the next 15 years emphasizing the importance of scaling up malaria responses and moving towards elimination. It also highlights the urgent need to increase investments across all interventions - including preventive measures diagnostic testing treatment and disease surveillance- as well as in harnessing innovation and expanding research. By adopting this strategy WHO Member States have endorsed the bold vision of a world free of malaria and set the ambitious new target of reducing the global malaria burden by 90% by 2030. They also agreed to strengthen health systems address emerging multi-drug and insecticide resistance and intensify national cross-border and regional efforts to scale up malaria responses to protect everyone at risk.

Malaria

Maria M. Mota,Ana Rodriguez
Malaria Book PDF

Author : Maria M. Mota,Ana Rodriguez
Publisher : Springer
Page : 278 pages
File Size : 49,7 Mb
Release : 2017-01-12
Category : Medical
ISBN : 9783319452104

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Malaria by Maria M. Mota,Ana Rodriguez Pdf

Currently, malaria kills more than 300,000 people per year, making it a top priority of world leaders and international organizations, who are working towards implementing and coordinating efforts to eradicate this disease. An effective malaria vaccine is recognized as the key element that will decide between success and failure in this fight. At present, despite intensive research efforts, such a vaccine is not yet available for use. However, there are a number of advanced candidate vaccines with high chances of success in the short term. Malaria: Immune Response to Infection and Vaccination provides a comprehensive view on the immune response to malaria and to the different vaccines under development. The book offers the following: - Contributions by top research leaders in the field, - Comparisons of the immune responses to both malaria infection and malaria vaccines, which are traditionally treated separately, - Coverage of the immune responses to the different stages of malaria, which are frequently treated as separate fields of research.

Malaria Parasites

Omolade Okwa
Malaria Parasites Book PDF

Author : Omolade Okwa
Publisher : BoD – Books on Demand
Page : 366 pages
File Size : 50,7 Mb
Release : 2012-03-30
Category : Medical
ISBN : 9789535103264

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Malaria Parasites by Omolade Okwa Pdf

Malaria is a global disease in the world today but most common in the poorest countries of the world, with 90% of deaths occurring in sub-Saharan Africa. This book provides information on global efforts made by scientist which cuts across the continents of the world. Concerted efforts such as symbiont based malaria control; new applications in avian malaria studies; development of humanized mice to study P.falciparium (the most virulent species of malaria parasite); and current issues in laboratory diagnosis will support the prompt treatment of malaria. Research is ultimately gaining more grounds in the quest to provide vaccine for the prevention of malaria. The book features research aimed to bring a lasting solution to the malaria problem and what we should be doing now to face malaria, which is definitely useful for health policies in the twenty first century.

Malaria

Robert Ménard
Malaria Book PDF

Author : Robert Ménard
Publisher : Humana Press
Page : 0 pages
File Size : 55,9 Mb
Release : 2012-09-19
Category : Medical
ISBN : 1627030255

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Malaria by Robert Ménard Pdf

Over the past ten years, many powerful new techniques have been developed that have dramatically changed malaria research. The second edition of Malaria: Methods and Protocols expands upon the previous edition with current, detailed techniques for laboratory research. With new chapters on parasite culture techniques, genome manipulation methods, 'omic' approaches, and techniques for studying the biology of the red blood cell and pre-erythrocytic stages of Plasmodium. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Malaria: Methods and Protocols, Second Edition, offers a comprehensive set of standard techniques for laboratory researchers.