Novel Enzyme And Whole Cell Biocatalysts

Author : Anwar Sunna,Richard Daniellou
Publisher : MDPI
Page : 332 pages
File Size : 44,8 Mb
Release : 2020-11-04
Category : Science
ISBN : 9783039434640

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Novel Enzyme and Whole-Cell Biocatalysts by Anwar Sunna,Richard Daniellou Pdf

The concept of a circular economy relies on waste reduction, valorization, and recycling. Global trends for “green” synthesis of chemicals have positioned the field of enzyme technology and biocatalysis (multi-enzymes and whole-cells) as an alternative for the synthesis of more social- and environmentally-responsible bio-based chemicals. Recent advances in synthetic biology, computational tools, and metabolic engineering have supported the discovery of new enzymes and the rational design of whole-cell biocatalysts. In this book, we highlight these current advances in the field of biocatalysis, with special emphasis on novel enzymes and whole-cell biocatalysts for applications in several industrial biotechnological applications.

Author : Anwar Sunna,Richard Daniellou
Publisher : Unknown
Page : 332 pages
File Size : 40,6 Mb
Release : 2020
Category : Electronic
ISBN : 3039434659

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Novel Enzyme and Whole-Cell Biocatalysts by Anwar Sunna,Richard Daniellou Pdf

The concept of a circular economy relies on waste reduction, valorization, and recycling. Global trends for “green” synthesis of chemicals have positioned the field of enzyme technology and biocatalysis (multi-enzymes and whole-cells) as an alternative for the synthesis of more social- and environmentally-responsible bio-based chemicals. Recent advances in synthetic biology, computational tools, and metabolic engineering have supported the discovery of new enzymes and the rational design of whole-cell biocatalysts. In this book, we highlight these current advances in the field of biocatalysis, with special emphasis on novel enzymes and whole-cell biocatalysts for applications in several industrial biotechnological applications.

Author : Wen-Yong Lou,Jun Ge,Changzhu Wu,Jesús Fernández Lucas
Publisher : Frontiers Media SA
Page : 492 pages
File Size : 40,5 Mb
Release : 2021-04-21
Category : Science
ISBN : 9782889667093

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Enzyme or Whole Cell Immobilization for Efficient Biocatalysis: Focusing on Novel Supporting Platforms and Immobilization Techniques by Wen-Yong Lou,Jun Ge,Changzhu Wu,Jesús Fernández Lucas Pdf

Author : José M. Guisán
Publisher : Springer Science & Business Media
Page : 447 pages
File Size : 40,6 Mb
Release : 2008-02-05
Category : Science
ISBN : 9781597450539

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Immobilization of Enzymes and Cells by José M. Guisán Pdf

Enzymes and whole cells are able to catalyze the most complex chemical processes under the most benign experimental and environmental conditions. In this way, enzymes and cells could be excellent catalysts for a much more sustainable chemical industry. However, enzymes and cells also have some limitations for nonbiological applications: fine chemistry, food chemistry, analysis, therapeutics, and so on. Enzymes and cells may be unstable, difficult to handle under nonconventional conditions, poorly selective toward synthetic substrates, and so forth. From this point of view, the transformation—from the laboratory to industry—of chemical processes catalyzed by enzymes and cells may be one of the most complex and exciting goals in biotechnology. For many industrial applications, enzymes and cells have to be immobilized, via very simple and cost-effective protocols, in order to be re-used over very long periods of time. From this point of view, immobilization, simplicity, and stabilization have to be strongly related concepts. Over the last 30 years, a number of protocols for the immobilization of cells and enzymes have been reported in scientific literature. However, only very few protocols are simple and useful enough to greatly improve the functional properties of enzymes and cells, activity, stability, selectivity, and related properties.

Author : Klaus Buchholz,Volker Kasche,Uwe Theo Bornscheuer
Publisher : John Wiley & Sons
Page : 609 pages
File Size : 52,5 Mb
Release : 2012-12-21
Category : Science
ISBN : 9783527672004

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Biocatalysts and Enzyme Technology by Klaus Buchholz,Volker Kasche,Uwe Theo Bornscheuer Pdf

This second edition of a bestselling textbook offers an instructive and comprehensive overview of our current knowledge of biocatalysis and enzyme technology. The book now contains about 40% more printed content. Three chapters are completely new, while the others have been thoroughly updated, and a section with problems and solutions as well as new case studies have been added. Following an introduction to the history of enzyme applications, the text goes on to cover in depth enzyme mechanisms and kinetics, production, recovery, characterization and design by protein engineering. The authors treat a broad range of applications of soluble and immobilized biocatalysts, including wholecell systems, the use of non-aqueous reaction systems, applications in organic synthesis, bioreactor design and reaction engineering. Methods to estimate the sustainability, important internet resources and their evaluation, and legislation concerning the use of biocatalysts are also covered.

Author : John Whittall,Peter W. Sutton
Publisher : John Wiley & Sons
Page : 392 pages
File Size : 51,8 Mb
Release : 2012-04-16
Category : Technology & Engineering
ISBN : 9781119943419

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Practical Methods for Biocatalysis and Biotransformations 2 by John Whittall,Peter W. Sutton Pdf

Biocatalysts are increasingly used by chemists engaged in fine chemical synthesis within both industry and academia. Today, there exists a huge choice of high-tech enzymes and whole cell biocatalysts, which add enormously to the repertoire of synthetic possibilities. Practical Methods for Biocatalysis and Biotransformations 2 is a "how-to" guide that focuses on the practical applications of enzymes and strains of microorganisms that are readily obtained or derived from culture collections. The sources of starting materials and reagents, hints, tips and safety advice (where appropriate) are given to ensure, as far as possible, that the procedures are reproducible. Comparisons to alternative methodology are given and relevant references to the primary literature are cited. This second volume – which can be used on its own or in combination with the first volume - concentrates on new applications and new enzyme families reported since the first volume. Contents include: introduction to recent developments and future needs in biocatalysts and synthetic biology in industry reductive amination enoate reductases for reduction of electron deficient alkenes industrial carbonyl reduction regio- and stereo- selective hydroxylation oxidation of alcohols selective oxidation industrial hydrolases and related enzymes transferases for alkylation, glycosylation and phosphorylation C-C bond formation and decarboxylation halogenation/dehalogenation/heteroatom oxidation tandem and sequential multi-enzymatic syntheses Practical Methods for Biocatalysis and Biotransformations 2 is an essential collection of biocatalytic methods for chemical synthesis which will find a place on the bookshelves of synthetic organic chemists, pharmaceutical chemists, and process R&D chemists in industry and academia.

Author : Sudheer D. V. N. Pamidimarri,Sushma Chauhan,Balasubramanian Velramar
Publisher : CRC Press
Page : 673 pages
File Size : 40,5 Mb
Release : 2024-06-28
Category : Science
ISBN : 9781000912326

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Whole-Cell Biocatalysis by Sudheer D. V. N. Pamidimarri,Sushma Chauhan,Balasubramanian Velramar Pdf

Whole-cell biocatalysis is a promising and emerging field of biological science that is mostly based on advancements in biosystems engineering for the production of useful products such as chemicals, fuels, and pharmaceuticals. It is a unique platform that provides an efficient catalytic system at affordable cost and with low maintenance. Recent studies have proven that whole-cell catalysis is very useful in conducting many complex and complicated chemical reactions that could be executed with greater ease and in an eco-friendly manner in ambient conditions with zero/minimal ecological effect. This has made whole-cell biocatalysis very popular and a center of significance in the field of modern biological catalysis. This new volume offers a comprehensive understanding of whole-cell biocatalysis, beginning with an introduction and an overview of relevant tools and techniques. It presents the basic as well as the advanced concepts of whole-cell biocatalysis, thus acting as a complete guide for the reader. It looks at the promising developments that have taken place in the past decade and discusses the application of computational tools, the use of metabolic flux systems, and the role of metabolic networks for the cell system development for whole-cell catalysis. The chapters explore whole-cell biocatalysis for the production of chemicals, of fuels, and for environmental restoration, with case studies and success stories that showcase new developments in the technology. This volume provides a valuable presentation of whole-cell biocatalysis for graduate students, faculty, industry professionals, and others working in biochemistry and bio-systems engineering.

Author : Maria Lujan Ferreira
Publisher : Academic Press
Page : 460 pages
File Size : 47,7 Mb
Release : 2022-11-12
Category : Science
ISBN : 9780323913775

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Biocatalyst Immobilization by Maria Lujan Ferreira Pdf

Biocatalyst Immobilization: Foundations and Applications provides a comprehensive overview of biocatalytic immobilization processes, as well as methods for study, characterization and application. Early chapters discuss current progress in enzyme immobilization and methods for selecting and pretreating enzymes prior to immobilization, with an emphasis on navigating common challenges and employing enzyme supports and post immobilization treatments to impact enzymatic activity. Process-based chapters instruct on measuring and reporting on enzyme immobilization efficiency, protein final content, quantification of reaction products, and the use of nanomaterials to characterize immobilized enzymes. Later chapters examine recent advances, including novel enzymatic reactors, multi-enzymatic biocatalysts, enzymatic biosensors, whole cell immobilization, the industrial application of immobilized enzymes, and perspectives on future trends. Provides a thorough overview of biocatalyst and enzyme immobilization for research and practical application Presents methods based content that instructs in enzyme immobilization pretreatment, enzyme supports, post immobilization treatments, measuring enzyme immobilization efficiency, quantification of reaction products, and whole cell immobilization Features chapter contributions from international leaders in the field

Author : W.-D. Fessner
Publisher : Springer Science & Business Media
Page : 273 pages
File Size : 55,8 Mb
Release : 2003-09-05
Category : Science
ISBN : 9783540681168

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Biocatalysis by W.-D. Fessner Pdf

Here, leading contributors from the forefront of this exciting technology present authoritative and timely reviews on the state of the art of biocatalysis. They cover the whole spectrum from the discovery of novel enzymes - by modern screening, evolutionary or immunological approaches - through immobilization techniques for technical processes, to their use in the asymmetric synthesis of important target compounds.

Author : Andreas S. Bommarius,Bettina R. Riebel-Bommarius
Publisher : John Wiley & Sons
Page : 644 pages
File Size : 43,6 Mb
Release : 2004-03-12
Category : Science
ISBN : 9783527303441

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Biocatalysis by Andreas S. Bommarius,Bettina R. Riebel-Bommarius Pdf

The whole range of biocatalysis, from a firm grounding in theoretical concepts to in-depth coverage of practical applications and future perspectives. The book not only covers reactions, products and processes with and from biological catalysts, but also the process of designing and improving such biocatalysts. One unique feature is that the fields of chemistry, biology and bioengineering receive equal attention, thus addressing practitioners and students from all three areas.

Author : Allen I. Laskin
Publisher : Butterworth-Heinemann
Page : 344 pages
File Size : 52,8 Mb
Release : 1985
Category : Science
ISBN : UCAL:B4986943

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Enzymes and Immobilized Cells in Biotechnology by Allen I. Laskin Pdf

Author : Winfried Hartmeier
Publisher : Springer Science & Business Media
Page : 217 pages
File Size : 47,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642733642

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Immobilized Biocatalysts by Winfried Hartmeier Pdf

Biotechnological processes often require the use of immobilized biocatalysts. This translation of the most successful German edition introduces the theoretical background of this rapidly growing field followed by a detailed description of the various techniques of immobilizing, characterizing, and using biocatalysts. The comprehensive discussion of possible applications in industrial processes and in basic research results in a practical guide for everyone involved in these techniques. Furthermore, some selected experiments are added in order to facilitate the understanding of the theoretical reports.

Author : Atsuo Tanaka,Tetsuya Tosa,Takeshi Kobayashi
Publisher : CRC Press
Page : 428 pages
File Size : 48,8 Mb
Release : 1992-10-16
Category : Medical
ISBN : 0824787447

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Industrial Application of Immobilized Biocatalysts by Atsuo Tanaka,Tetsuya Tosa,Takeshi Kobayashi Pdf

Offers practical examples of bioreactor systems that use immobilized biocatalysts - including enzymes and microbial cells - that have been implemented on the industrial level in Japan and Denmark. The book provides information on the current status of successful new bioreactor technologies.

Author : Junhua (Alex) Tao,Romas Joseph Kazlauskas
Publisher : John Wiley & Sons
Page : 500 pages
File Size : 52,8 Mb
Release : 2011-08-30
Category : Technology & Engineering
ISBN : 9780470437780

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Biocatalysis for Green Chemistry and Chemical Process Development by Junhua (Alex) Tao,Romas Joseph Kazlauskas Pdf

This book describes recent progress in enzyme-driven green syntheses of industrially important molecules. The first three introductory chapters overview recent technological advances in enzymes and cell-based transformations, and green chemistry metrics for synthetic efficiency. The remaining chapters are directed to case studies in biotechnological production of pharmaceuticals (small molecules, natural products and biologics), flavors, fragrance and cosmetics, fine chemicals, value-added chemicals from glucose and biomass, and polymeric materials. The book is aimed to facilitate the industrial applications of this powerful and emerging green technology, and catalyze the advancement of the technology itself.

Author : Qayyum Husain,Mohammad Fahad Ullah
Publisher : Springer Nature
Page : 341 pages
File Size : 49,6 Mb
Release : 2019-09-03
Category : Science
ISBN : 9783030250232

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Biocatalysis by Qayyum Husain,Mohammad Fahad Ullah Pdf

This book introduces readers to industrially important enzymes and discusses in detail their structures and functions, as well as their manifold applications. Due to their selective biocatalytic capabilities, enzymes are used in a broad range of industries and processes. The book highlights selected enzymes and their applications in agriculture, food processing and discoloration, as well as their role in biomedicine. In turn, it discusses biochemical engineering strategies such as enzyme immobilization, metabolic engineering, and cross-linkage of enzyme aggregates, and critically weighs their pros and cons. Offering a wealth of information, and stimulating further research by presenting new concepts on enzymatic catalytic functions in basic and applied contexts, the book represents a valuable asset for researchers from academia and industry who are engaged in biochemical engineering, microbiology and biotechnology.