Obesity And Metabolism

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Obesity and Metabolism

Author : Márta Korbonits
Publisher : Karger Medical and Scientific Publishers
Page : 305 pages
File Size : 44,6 Mb
Release : 2008-01-01
Category : Medical
ISBN : 9783805584296

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Obesity and Metabolism by Márta Korbonits Pdf

It has become increasingly difficult to keep up with the growing body of literature on the genetics, metabolic phenotype and treatment of obesity. This volume brings together an array of chapters from many of the foremost authorities and researchers in this area. Key advances in the genetics of obesity are summarized and the effects of obesity in pregnancy, childhood and old age explored. By scrutinizing the hormones and enzymes most recently implicated in the development, maintenance and consequences of obesity, the biochemical and physiological background of the abnormal metabolism of obesity is mapped out. Furthermore, a practical update on clinical approach and treatment of obesity is offered. Finally, the social aspects of obesity and the view of the obese body in art throughout the centuries are reflected. A valuable overview of causes, metabolic disturbances and treatment options, this volume will appeal to those with an interest in clinical as well as pathophysiological and genetic aspects of obesity. Furthermore, it will provide useful reading for scientists and students who would like to broaden and update their knowledge in this area.

Obesity and Lipotoxicity

Author : Ayse Basak Engin,Atilla Engin
Publisher : Springer
Page : 624 pages
File Size : 41,7 Mb
Release : 2017-06-05
Category : Science
ISBN : 9783319483825

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Obesity and Lipotoxicity by Ayse Basak Engin,Atilla Engin Pdf

Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. “Obesity and Lipotoxicity” is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. “Lipotoxicity and Obesity” will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field.

Fat Detection

Author : Jean-Pierre Montmayeur,Johannes le Coutre
Publisher : CRC Press
Page : 643 pages
File Size : 45,5 Mb
Release : 2009-09-14
Category : Science
ISBN : 1420067761

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Fat Detection by Jean-Pierre Montmayeur,Johannes le Coutre Pdf

Presents the State-of-the-Art in Fat Taste Transduction A bite of cheese, a few potato chips, a delectable piece of bacon – a small taste of high-fat foods often draws you back for more. But why are fatty foods so appealing? Why do we crave them? Fat Detection: Taste, Texture, and Post Ingestive Effects covers the many factors responsible for the sensory appeal of foods rich in fat. This well-researched text uses a multidisciplinary approach to shed new light on critical concerns related to dietary fat and obesity. Outlines Compelling Evidence for an Oral Fat Detection System Reflecting 15 years of psychophysical, behavioral, electrophysiological, and molecular studies, this book makes a well-supported case for an oral fat detection system. It explains how gustatory, textural, and olfactory information contribute to fat detection using carefully designed behavioral paradigms. The book also provides a detailed account of the brain regions that process the signals elicited by a fat stimulus, including flavor, aroma, and texture. This readily accessible work also discusses: The importance of dietary fats for living organisms Factors contributing to fat preference, including palatability Brain mechanisms associated with appetitive and hedonic experiences connected with food consumption Potential therapeutic targets for fat intake control Genetic components of human fat preference Neurological disorders and essential fatty acids Providing a comprehensive review of the literature from the leading scientists in the field, this volume delivers a holistic view of how the palatability and orosensory properties of dietary fat impact food intake and ultimately health. Fat Detection represents a new frontier in the study of food perception, food intake, and related health consequences.

Obesity and Diabetes

Author : Anthony H. Barnett,Sudhesh Kumar
Publisher : John Wiley & Sons
Page : 324 pages
File Size : 54,9 Mb
Release : 2005-04-08
Category : Medical
ISBN : 9780470011096

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Obesity and Diabetes by Anthony H. Barnett,Sudhesh Kumar Pdf

Obesity has become the most common chronic disease of the present day, with significant increases in prevalence in populations across the world and all age groups. This has resulted in a dramatic increase in obesity-related metabolic and cardiovascular complications, making it an important public health issue. Type 2 diabetes associated with obesity or 'diabesity' is today the most common form of type 2 diabetes. It is also associated with a number of other cardiovascular risk factors, which constitute the metabolic syndrome. Effective management of 'diabesity' is crucial to the reduction of morbidity and premature mortality due to cardiovascular disease. This book comprises chapters written by leading international experts on various aspects of obesity-related diabetes. As a practical reference guide, it is suitable for all professionals with an interest in this field. Emerging problems such as childhood 'diabesity' and the impact of obesity on polycystic ovary syndrome will be of interest not only to paediatricians and endocrinologists, but also to general practitioners and other healthcare professionals. The contemporary approach to the clinical assessment of obesity and its management in both primary and secondary care settings is also described.

Weighing the Options

Author : Institute of Medicine,Committee to Develop Criteria for Evaluating the Outcomes of Approaches to Prevent and Treat Obesity
Publisher : National Academies Press
Page : 296 pages
File Size : 46,6 Mb
Release : 1995-03-01
Category : Medical
ISBN : 9780309132572

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Weighing the Options by Institute of Medicine,Committee to Develop Criteria for Evaluating the Outcomes of Approaches to Prevent and Treat Obesity Pdf

Nearly one out of every three adults in America is obese and tens of millions of people in the United States are dieting at any one time. This has resulted in a weight-loss industry worth billions of dollars a year and growing. What are the long-term results of weight-loss programs? How can people sort through the many programs available and select one that is right for them? Weighing the Options strives to answer these questions. Despite widespread public concern about weight, few studies have examined the long-term results of weight-loss programs. One reason that evaluating obesity management is difficult is that no other treatment depends so much on an individual's own initiative and state of mind. Now, a distinguished group of experts assembled by the Institute of Medicine addresses this compelling issue. Weighing the Options presents criteria for evaluating treatment programs for obesity and explores what these criteria meanâ€"to health care providers, program designers, researchers, and even overweight people seeking help. In presenting its criteria the authors offer a wealth of information about weight loss: how obesity is on the rise, what types of weight-loss programs are available, how to define obesity, how well we maintain weight loss, and what approaches and practices appear to be most successful. Information about weight-loss programsâ€"their clients, staff qualifications, services, and success ratesâ€"necessary to make wise program choices is discussed in detail. The book examines how client demographics and characteristicsâ€"including health status, knowledge of weight-loss issues, and attitude toward weight and body imageâ€"affect which programs clients choose, how successful they are likely to be with their choices, and what this means for outcome measurement. Short- and long-term safety consequences of weight loss are discussed as well as clinical assessment of individual patients. The authors document the health risks of being overweight, summarizing data indicating that even a small weight loss reduces the risk of disease and depression and increases self-esteem. At the same time, weight loss has been associated with some poor outcomes, and the book discusses the implications for program evaluation. Prevention can be even more important than treatment. In Weighing the Options, programs for population groups, efforts targeted to specific groups at high risk for obesity, and prevention of further weight gain in obese individuals get special attention. This book provides detailed guidance on how the weight-loss industry can improve its programs to help people be more successful at long-term weight loss. And it provides consumers with tips on selecting a program that will improve their chances of permanently losing excess weight.

Metabolism and Pathophysiology of Bariatric Surgery

Author : Victor R Preedy,Rajkumar Rajendram,Colin R Martin
Publisher : Academic Press
Page : 685 pages
File Size : 55,9 Mb
Release : 2016-11-26
Category : Health & Fitness
ISBN : 9780128040638

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Metabolism and Pathophysiology of Bariatric Surgery by Victor R Preedy,Rajkumar Rajendram,Colin R Martin Pdf

Pathophysiology of Bariatric Surgery: Metabolism, Nutrition, Procedures, Outcomes and Adverse Effects uses a metabolic and nutritional theme to explain the complex interrelationships between obesity and metabolic profiles before and after bariatric surgery. The book is sectioned into seven distinct areas, Features of Obesity, Surgical Procedures, Nutritional Aspects, Metabolic Aspects, Diabetes, Insulin Resistance and Glucose Control, Cardiovascular and Physiological Effects, and Psychological and Behavioral Effects. Included is coverage on the various types of bariatric surgery, including Roux-en-Y gastric bypass, gastric banding, sleeve gastrectomy, biliopancreatic diversion, and jejunoileal bypass, as well as the variations upon these procedures. Provides information on diet, nutrition, surgical procedures, outcomes, and side effects in relation to bariatric surgery in one comprehensive text Contains a Dictionary of Terms, Key Facts, and Summary Points in each chapter Includes access to a companion website with accompanying videos

Thyroid, Obesity and Metabolism

Author : Livio Luzi
Publisher : Springer
Page : 0 pages
File Size : 48,9 Mb
Release : 2022-08-29
Category : Medical
ISBN : 3030802698

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Thyroid, Obesity and Metabolism by Livio Luzi Pdf

This book will provide readers with up-to-date information on thyroid diseases, obesity and metabolic syndrome. The innovative element is the presentation and exploration of possible connections linking thyroid diseases and metabolism dysfunction. Starting from the classification and diagnosis of thyroid diseases, obesity and metabolic syndrome, techniques to study and treat each of the mentioned diseases are given in an easy-to-use way. This volume will be a useful tool for endocrinologists, diabetologists, dieticians, and any professionals involved in the treatment of thyroid diseases.

Metabolic Basis of Obesity

Author : Rexford S. Ahima
Publisher : Springer Science & Business Media
Page : 395 pages
File Size : 55,7 Mb
Release : 2010-11-16
Category : Medical
ISBN : 9781441916075

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Metabolic Basis of Obesity by Rexford S. Ahima Pdf

The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on behaviors that lead to obesity, in particular to over consumption of energy-dense food and to sedentary lifestyle. However, obesity is an extremely complex condition with poorly defined pathogenesis. Thanks to greatly enhanced research in the area, the discovery of pathways in the brain and peripheral organs that mediate energy homeostasis has provided a framework for understanding the biological basis of obesity. Metabolic Basis of Obesity adds an important new dimension to the growing literature on obesity by offering a comprehensive review of specifically how metabolic imbalance culminates in obesity. Developed by a team of expert authors, this important title discusses the principles of energy balance, genetics of body weight regulation, hormones and adipokines, and metabolic pathways in the brain, liver, muscle and fat, to name just several of the areas covered. The book also examines the connection between obesity and diabetes, cardiovascular disease and other complications. Current and future diagnostic and treatment strategies are also reviewed. Comprehensive and timely, Metabolic Basis of Obesity is an essential reference for understanding the burgeoning problem of obesity.

Overweight and the Metabolic Syndrome:

Author : George A. Bray,Louisiana State University,Donna Ryan
Publisher : Springer Science & Business Media
Page : 347 pages
File Size : 44,5 Mb
Release : 2007-02-16
Category : Medical
ISBN : 9780387321646

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Overweight and the Metabolic Syndrome: by George A. Bray,Louisiana State University,Donna Ryan Pdf

This timely book provides an overview of topics related to obesity. These include associated health risks, childhood obesity, genetics, evaluation, treatment, behavioral strategies, and successes and failures in preventing obesity. The volume covers evaluation guidelines, different approaches to treatment, including diet, exercise, behavior, drugs, and surgery to deal with the current world-wide obesity epidemic.

The Metabolic Syndrome and Obesity

Author : George A. Bray
Publisher : Springer Science & Business Media
Page : 304 pages
File Size : 53,6 Mb
Release : 2008-01-23
Category : Science
ISBN : 9781597454315

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The Metabolic Syndrome and Obesity by George A. Bray Pdf

This book presents an up-to-date survey of the current scientific understanding of obesity and the metabolic syndrome, as well as an overview of the most significant changes to the field over the past 30 years. The book defines obesity and realistically assesses its prevalence. It further examines and evaluates the success of traditional cognitive behavioral treatment. This volume is a thorough reference for obesity and the metabolic syndrome.

Polycystic Ovary Syndrome

Author : Andrea Dunaif,R. Jeffrey Chang,Stephen Franks,Richard S. Legro
Publisher : Springer Science & Business Media
Page : 350 pages
File Size : 49,9 Mb
Release : 2008-01-12
Category : Medical
ISBN : 9781597451086

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Polycystic Ovary Syndrome by Andrea Dunaif,R. Jeffrey Chang,Stephen Franks,Richard S. Legro Pdf

This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.

TNF Pathophysiology

Author : George Kollias,Petros P. Sfikakis
Publisher : Karger Medical and Scientific Publishers
Page : 223 pages
File Size : 50,5 Mb
Release : 2010-01-01
Category : Medical
ISBN : 9783805593830

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TNF Pathophysiology by George Kollias,Petros P. Sfikakis Pdf

TNF is a multifunctional proinflammatory cytokine central to the development and homeostasis of the immune system and a regulator of cell activation, differentiation and death. Recent decades have seen an enormous scientific and clinical interest in the function of TNF in physiology and disease. A vast amount of data has been accumulated at the biochemical, molecular and cellular level, establishing TNF as a prototype for in-depth understanding of the physiological and pathogenic functions of cytokines. This volume covers several current aspects of TNF regulation and function, including transcriptional and posttranscriptional control mechanisms, cellular modes of action, signaling networks that mediate its effect, involvement in pathogenesis and clinical outcomes of TNF antagonists. It combines basic science at the molecular and cellular level with research in animal models of disease and clinical findings to provide a comprehensive review of recent developments in TNF biology. A thorough understanding of the mechanisms by which this key molecular player is produced and functions to regulate cell biology, immunity and disease postulates novel paradigms on how genes contribute to the development and physiology of biological systems.

Sleep Hypoventilation: A State-of-the-Art Overview, An Issue of Sleep Medicine Clinics,

Author : Babak Mokhlesi
Publisher : Elsevier Health Sciences
Page : 201 pages
File Size : 47,5 Mb
Release : 2014-10-07
Category : Medical
ISBN : 9780323326810

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Sleep Hypoventilation: A State-of-the-Art Overview, An Issue of Sleep Medicine Clinics, by Babak Mokhlesi Pdf

This issue on Hypoventilation Syndrome covers a variety of topics such as Sleep hypoventilation: Diagnostic considerations and technological limitations,Pathophysiology of hypoventilation during sleep,Advances in PAP treatment modalities for hypoventilation syndromes,Scoring abnormal respiratory events on polysomnography during noninvasive ventilation,OHS Epidemiology and diagnosis,OHS outcomes,Non-PAP treatment modalities in OHS, Pulmonary overlap syndromes,Noninvasive ventilation during sleep in stable COPD and more!

Bariatric Endocrinology

Author : J. Michael Gonzalez-Campoy,Daniel L. Hurley,W. Timothy Garvey
Publisher : Springer
Page : 453 pages
File Size : 47,8 Mb
Release : 2018-10-26
Category : Medical
ISBN : 9783319956558

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Bariatric Endocrinology by J. Michael Gonzalez-Campoy,Daniel L. Hurley,W. Timothy Garvey Pdf

This unique book – the first ever on bariatric endocrinology – is a comprehensive endocrine and metabolism approach to the diseases that result from excess fat mass accumulation and adipose tissue dysfunction. It takes an approach that places adipose tissue at the center of the clinical approach to patients, as opposed to the complications of adipose tissue accumulation and dysfunction, which has been the dominant approach to date. Initial chapters include discussion of adipose tissue physiology and pathophysiology (adiposopathy), hormonal, central nervous system, and gut microbiome regulation of energy balance and stores, and primary and secondary causes of adipose tissue weight gain. Subsequent chapters cover the evaluation and treatment of dyslipidemia, insulin resistance and hyperglycemic states, hypertension, neoplasia, and gonadal function in men and women. Management strategies, such as nutrition, physical activity, pharmacotherapy, and bariatric procedures, round out the presentation. Each chapter is bookended by bullet-pointed clinical pearls at the beginning and a full reading list at the end. Written and edited by experts in the field of endocrinology and obesity management, Bariatric Endocrinology redefines practice to focus not just on weight loss as measured in pounds lost, but on adipose tissue mass and pathology, decreasing fat mass for adiposity-related diseases and returning adipose tissue to normal function.

A Guide to Obesity and the Metabolic Syndrome

Author : George A. Bray
Publisher : CRC Press
Page : 412 pages
File Size : 47,9 Mb
Release : 2011-03-28
Category : Medical
ISBN : 9781439814581

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A Guide to Obesity and the Metabolic Syndrome by George A. Bray Pdf

In the historical record there is abundant evidence that obesity was a medical and health concern as long as medicine has been practiced. The idea of diet and exercise are bulwarks in the fight against obesity in history from the time of Hippocrates to the 16th century—a span of 2,000 years. However, our scientific understanding of this problem is only a little over 200 years old. An examination of the root cause of what many consider the obesity epidemic, A Guide to Obesity and the Metabolic Syndrome traces the origins and types of obesity and its treatment. Examining in detail the developing treatment for obesity, this book provides: A history of obesity, including treatment, proposed causes, and perceptions An examination of the causes and problems associated with obesity A discussion of lifestyle, diet, exercise, and treatment strategies A detailed look at the medications and surgeries available for obesity The fact that we have an epidemic of obesity today that is covering the globe suggests that the strategically simple ideas of eating less and exercising more, ideas that require commitment and personal involvement by the individual, have not been very successful. As we move forward in trying to understand this problem, we need to be alert to strategies and tactics that may not require individual motivation and commitment—history has shown that they do not work well. This book supplies guidance on developing and designing novel strategic interventions against obesity and metabolic disorders.