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Observing Protein Dynamics And Conformational Changes By Ensemble And Single Molecule Fluorescence Spectroscopy Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Observing Protein Dynamics And Conformational Changes By Ensemble And Single Molecule Fluorescence Spectroscopy book. This book definitely worth reading, it is an incredibly well-written.
Author : So Yeon Kim
Publisher : Unknown
Page : 420 pages
File Size : 44,6 Mb
Release : 2008
Category : Electronic
ISBN : STANFORD:36105126998595
Author : Markus Sauer,Johan Hofkens,Jörg Enderlein
Publisher : John Wiley & Sons
Page : 425 pages
File Size : 55,6 Mb
Release : 2010-12-23
Category : Science
ISBN : 9783527633524
Providing much-needed information on fluorescence spectroscopy and microscopy, this ready reference covers detection techniques, data registration, and the use of spectroscopic tools, as well as new techniques for improving the resolution of optical microscopy below the resolution gap. Starting with the basic principles, the book goes on to treat fluorophores and labeling, single-molecule fluorescence spectroscopy and enzymatics, as well as excited state energy transfer, and super-resolution fluorescence imaging. Examples show how each technique can help in obtaining detailed and refined information from individual molecular systems.
Author : Toshio Yanagida,Yoshiharu Ishii
Publisher : John Wiley & Sons
Page : 346 pages
File Size : 42,7 Mb
Release : 2008-12-04
Category : Science
ISBN : 9783527626144
In this first comprehensive resource to cover the application of single molecule techniques to biological measurements, the pioneers in the field show how to both set up and interpret a single molecule experiment. Following an introduction to single molecule measurements and enzymology, the expert authors consider molecular motors and mechanical properties before moving on to the applications themselves. Detailed discussions of studies on protein enzymes, ribozymes and nucleic acids are also included.
Author : Christoph Bräuchle,Don Carroll Lamb,Jens Michaelis
Publisher : John Wiley & Sons
Page : 359 pages
File Size : 51,5 Mb
Release : 2009-10-30
Category : Science
ISBN : 3527628371
Closing a gap in the literature, this handbook gathers all the information on single particle tracking and single molecule energy transfer. It covers all aspects of this hot and modern topic, from detecting virus entry to membrane diffusion, and from protein folding using spFRET to coupled dye systems, as well recent achievements in the field. Throughout, the first-class editors and top international authors present content of the highest quality, making this a must-have for physical chemists, spectroscopists, molecular physicists and biochemists.
Author : Anonim
Publisher : Academic Press
Page : 3533 pages
File Size : 45,5 Mb
Release : 2012-04-12
Category : Science
ISBN : 9780080957180
Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics, Nine Volume Set will help bridge that communication gap. Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics, Nine Volume Set provides definitive introductions to a broad array of topics, uniting different areas of biophysics research - from the physical techniques for studying macromolecular structure to protein folding, muscle and molecular motors, cell biophysics, bioenergetics and more. The result is this comprehensive scientific resource - a valuable tool both for helping researchers come to grips quickly with material from related biophysics fields outside their areas of expertise, and for reinforcing their existing knowledge. Biophysical research today encompasses many areas of biology. These studies do not necessarily share a unique identifying factor. This work unites the different areas of research and allows users, regardless of their background, to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding The field of biophysics counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Biophysics fills this vacuum, being a definitive work on biophysics. It will help users apply context to the diverse journal literature offering, and aid them in identifying areas for further research Chief Editor Edward Egelman (E-I-C, Biophysical Journal) has assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource
Author : George Knopf,Amarjeet S. Bassi,George K. Knopf
Publisher : CRC Press
Page : 676 pages
File Size : 40,5 Mb
Release : 2006-12-26
Category : Science
ISBN : 9781420019506
Synergy is the key to creating more intelligent biosensors. Engineers develop smaller, more integrated technologies; biologists and chemists develop increasingly selective and sensitive sensor elements; material scientists develop ways to bring it all together. However, most books focus only on the chemistry aspects of biosensor technologies. With
Author : Rainer Blatt,Jurgen Eschner,Dietrich Leibfried,Ferdinand Schmidt-kaler
Publisher : World Scientific
Page : 398 pages
File Size : 54,9 Mb
Release : 1999-12-28
Category : Science
ISBN : 9789814543170
The 14th International Conference on Laser Spectroscopy brought together spectroscopists from all over the world working in the very diverse and still growing field of laser spectroscopy. Spanning the area from fundamental issues (such as experiments testing the foundations of quantum mechanics), to atomic and molecular spectroscopy, precision spectroscopy and matter wave optics to Bose-Einstein condensation, covering quantum optics and the new field of quantum computation and quantum information, up to nonlinear optics and ultrashort pulse spectroscopy, and medical applications of laser spectroscopy, the conference addressed a large number of modern scientific issues at the highest level.
Author : Ke-li Han,Xin Zhang,Ming-jun Yang
Publisher : Springer Science & Business Media
Page : 488 pages
File Size : 41,7 Mb
Release : 2014-01-20
Category : Medical
ISBN : 9783319029702
This book discusses how biological molecules exert their function and regulate biological processes, with a clear focus on how conformational dynamics of proteins are critical in this respect. In the last decade, the advancements in computational biology, nuclear magnetic resonance including paramagnetic relaxation enhancement, and fluorescence-based ensemble/single-molecule techniques have shown that biological molecules (proteins, DNAs and RNAs) fluctuate under equilibrium conditions. The conformational and energetic spaces that these fluctuations explore likely contain active conformations that are critical for their function. More interestingly, these fluctuations can respond actively to external cues, which introduces layers of tight regulation on the biological processes that they dictate. A growing number of studies have suggested that conformational dynamics of proteins govern their role in regulating biological functions, examples of this regulation can be found in signal transduction, molecular recognition, apoptosis, protein / ion / other molecules translocation and gene expression. On the experimental side, the technical advances have offered deep insights into the conformational motions of a number of proteins. These studies greatly enrich our knowledge of the interplay between structure and function. On the theoretical side, novel approaches and detailed computational simulations have provided powerful tools in the study of enzyme catalysis, protein / drug design, protein / ion / other molecule translocation and protein folding/aggregation, to name but a few. This work contains detailed information, not only on the conformational motions of biological systems, but also on the potential governing forces of conformational dynamics (transient interactions, chemical and physical origins, thermodynamic properties). New developments in computational simulations will greatly enhance our understanding of how these molecules function in various biological events.
Author : Anonim
Publisher : Unknown
Page : 790 pages
File Size : 49,7 Mb
Release : 2008
Category : Mathematical physics
ISBN : UCSD:31822036916187
Author : Alexander E. Knight
Publisher : Academic Press
Page : 368 pages
File Size : 54,6 Mb
Release : 2009-02-26
Category : Science
ISBN : 008092123X
Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological molecules within a live cell or in culture. These approaches, amongst the most exciting tools available in biology today, offer powerful new ways to elucidate biological function, both in terms of revealing mechanisms of action on a molecular level as well as tracking the behaviour of molecules in living cells. This book provides the first complete and authoritative treatment of this rapidly emerging field, explicitly from a biological perspective. The contents are organized by biological system or molecule. Each chapter discusses insights that have been revealed about their mechanism, structure or function by single molecule techniques. Among the topics covered are enzymes, motor proteins, membrane channels, DNA, ribozymes, cytoskeletal proteins, and other key molecules of current interest. An introduction by the editor provides a concise review of key principles and an historical overview. The last section discusses applications in molecular diagnostics and drug discovery. * Organized by biological system or molecule. * Each chapter discusses insights into mechanism of action, structure, and function * Covers enzymes, motor proteins, membrane channels, DNA, ribozymes, etc. * Includes an introduction to key principles and an historical overview. * Discusses applications in molecular diagnostics and drug discovery. * Provides an expert's perspective on future developments.
Author : Anonim
Publisher : ScholarlyEditions
Page : 769 pages
File Size : 44,5 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9781464991691
Hemeproteins—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Hemeproteins. The editors have built Hemeproteins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Hemeproteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hemeproteins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : Iain Campbell
Publisher : Oxford University Press
Page : 364 pages
File Size : 45,5 Mb
Release : 2012-02-16
Category : Medical
ISBN : 9780199642144
Biophysical Techniques explains in a readily-accessible way the basics of the various biophysical methods available so students can understand the principles behind the different methods used, and begin to appreciate which tools can be used to probe different biological questions, and the pros and cons of each.
Author : Anonim
Publisher : Academic Press
Page : 2785 pages
File Size : 45,5 Mb
Release : 2010-10-29
Category : Science
ISBN : 9780123743961
From the Introduction: Nanotechnology and its underpinning sciences are progressing with unprecedented rapidity. With technical advances in a variety of nanoscale fabrication and manipulation technologies, the whole topical area is maturing into a vibrant field that is generating new scientific research and a burgeoning range of commercial applications, with an annual market already at the trillion dollar threshold. The means of fabricating and controlling matter on the nanoscale afford striking and unprecedented opportunities to exploit a variety of exotic phenomena such as quantum, nanophotonic and nanoelectromechanical effects. Moreover, researchers are elucidating new perspectives on the electronic and optical properties of matter because of the way that nanoscale materials bridge the disparate theories describing molecules and bulk matter. Surface phenomena also gain a greatly increased significance; even the well-known link between chemical reactivity and surface-to-volume ratio becomes a major determinant of physical properties, when it operates over nanoscale dimensions. Against this background, this comprehensive work is designed to address the need for a dynamic, authoritative and readily accessible source of information, capturing the full breadth of the subject. Its six volumes, covering a broad spectrum of disciplines including material sciences, chemistry, physics and life sciences, have been written and edited by an outstanding team of international experts. Addressing an extensive, cross-disciplinary audience, each chapter aims to cover key developments in a scholarly, readable and critical style, providing an indispensible first point of entry to the literature for scientists and technologists from interdisciplinary fields. The work focuses on the major classes of nanomaterials in terms of their synthesis, structure and applications, reviewing nanomaterials and their respective technologies in well-structured and comprehensive articles with extensive cross-references. It has been a constant surprise and delight to have found, amongst the rapidly escalating number who work in nanoscience and technology, so many highly esteemed authors willing to contribute. Sharing our anticipation of a major addition to the literature, they have also captured the excitement of the field itself in each carefully crafted chapter. Along with our painstaking and meticulous volume editors, full credit for the success of this enterprise must go to these individuals, together with our thanks for (largely) adhering to the given deadlines. Lastly, we record our sincere thanks and appreciation for the skills and professionalism of the numerous Elsevier staff who have been involved in this project, notably Fiona Geraghty, Megan Palmer and Greg Harris, and especially Donna De Weerd-Wilson who has steered it through from its inception. We have greatly enjoyed working with them all, as we have with each other.
Author : Chi-Kuang Wen,Yunde Zhao,Yong-Ling Ruan
Publisher : Frontiers Media SA
Page : 416 pages
File Size : 53,7 Mb
Release : 2018-12-21
Category : Electronic
ISBN : 9782889456864
One of the goals of plant science is to improve agricultural sustainability, increasing yield, food diversity, and nutrition, while minimizing the negative impact on our environment. In response to internal and external cues, plant hormones control various aspects of plant growth and development. The wealth of our knowledge on plant hormones shall greatly advance sustainable agriculture.
Author : Tamiki Komatsuzaki,Masaru Kawakami,Satoshi Takahashi,Haw Yang,Robert J. Silbey
Publisher : John Wiley & Sons
Page : 403 pages
File Size : 41,6 Mb
Release : 2011-11-16
Category : Science
ISBN : 9781118131381
Discover the experimental and theoretical developments in optical single-molecule spectroscopy that are changing the ways we think about molecules and atoms The Advances in Chemical Physics series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. This latest volume explores the advent of optical single-molecule spectroscopy, and how atomic force microscopy has empowered novel experiments on individual biomolecules, opening up new frontiers in molecular and cell biology and leading to new theoretical approaches and insights. Organized into two parts—one experimental, the other theoretical—this volume explores advances across the field of single-molecule biophysics, presenting new perspectives on the theoretical properties of atoms and molecules. Single-molecule experiments have provided fresh perspectives on questions such as how proteins fold to specific conformations from highly heterogeneous structures, how signal transductions take place on the molecular level, and how proteins behave in membranes and living cells.This volume is designed to further contribute to the rapid development of single-molecule biophysics research. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series serves as the perfect supplement to any advanced graduate class devoted to the study of chemical physics.