Optical Techniques In Regenerative Medicine

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Optical Techniques in Regenerative Medicine

Author : Stephen P. Morgan,Felicity R. Rose,Stephen J. Matcher
Publisher : Taylor & Francis
Page : 438 pages
File Size : 46,9 Mb
Release : 2016-04-19
Category : Technology & Engineering
ISBN : 9781439854969

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Optical Techniques in Regenerative Medicine by Stephen P. Morgan,Felicity R. Rose,Stephen J. Matcher Pdf

In regenerative medicine, tissue engineers largely rely on destructive and time-consuming techniques that do not allow in situ and spatial monitoring of tissue growth. Furthermore, once the therapy is implanted in the patient, clinicians are often unable to monitor what is happening in the body. To tackle these barriers, optical techniques have been developed to image and characterize many tissue properties, fabricate tissue engineering scaffolds, and characterize the properties of the scaffolds. Optical Techniques in Regenerative Medicine illustrates how to use optical imaging techniques and instrumentation for the fabrication, assessment, and longitudinal monitoring of regenerative medicine therapies. The book covers optical coherence tomography, acousto-optic imaging, Raman spectroscopy, machine vision, bioluminescence, second harmonic generation microscopy, multi-photon microscopy, coherent anti-Stokes Raman scattering, fluorescence spectroscopy, and light scattering spectroscopy. Each chapter provides an overview of a particular technique, its advantages and limitations in terms of structural and functional information, and examples of applications in regenerative medicine. The future evolution of regenerative medicine from academic research to viable clinical alternatives to conventional treatments is dependent on the development of non-destructive analytical techniques that can elucidate the stages of tissue development both in vitro and in vivo as well as track the fate of cells following injection. This practical book demonstrates the vital role of optical techniques in the dynamic field of regenerative medicine. It guides regenerative medicine researchers toward finding the most appropriate technique for their applications and helps biophotonics researchers see where their technologies can be applied.

Optics in Tissue Engineering and Regenerative Medicine

Author : Sean Kirkpatrick,Ruikang K. Wang
Publisher : SPIE-International Society for Optical Engineering
Page : 138 pages
File Size : 55,5 Mb
Release : 2007
Category : Medical
ISBN : UOM:39015069218249

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Optics in Tissue Engineering and Regenerative Medicine by Sean Kirkpatrick,Ruikang K. Wang Pdf

Proceedings of SPIE offer access to the latest innovations in research and technology and are among the most cited references in patent literature.

Principles of Regenerative Medicine

Author : Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Publisher : Academic Press
Page : 1202 pages
File Size : 45,9 Mb
Release : 2010-12-16
Category : Science
ISBN : 0123814235

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Principles of Regenerative Medicine by Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem Pdf

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Optical Nanoscopy and Novel Microscopy Techniques

Author : Peng Xi
Publisher : CRC Press
Page : 261 pages
File Size : 44,8 Mb
Release : 2014-09-19
Category : Science
ISBN : 9781466586307

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Optical Nanoscopy and Novel Microscopy Techniques by Peng Xi Pdf

Microscopy is at the forefront of multidisciplinary research. It was developed by physicists, made specific by chemists, and applied by biologists and doctors to better understand how the human body works. For this very reason, the field has been revolutionized in past decades. The objective of Optical Nanoscopy and Novel Microscopy Techniques is to choose some of those revolutionary ideas and serve a general audience from broad disciplines to achieve a fundamental understanding of these technologies and to better apply them in their daily research. The book begins with coverage of super-resolution optical microscopy, which discusses targeted modulation such as STED and SIM or localization methods such as PALM. It then discusses novel development of fluorescent probes, such as organic small-molecule probes, fluorescent proteins, and inorganic labels such as quantum dots. Finally, it describes advanced optical microscopy, such as fluorescence lifetime imaging, fiber optic microscopy, scanning ion conductance microscopy, and the joining of optics and acoustics—photoacoustic microscopy. Following each chapter, a detailed list of references is provided. Problems at the end of each chapter are also included.

Handbook of Tissue Optical Clearing

Author : Valery V. Tuchin,Dan Zhu,Elina A. Genina
Publisher : CRC Press
Page : 682 pages
File Size : 40,8 Mb
Release : 2022-02-04
Category : Science
ISBN : 9781000466300

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Handbook of Tissue Optical Clearing by Valery V. Tuchin,Dan Zhu,Elina A. Genina Pdf

Biomedical photonics is currently one of the fastest growing fields, connecting research in physics, optics, and electrical engineering coupled with medical and biological applications. It allows for the structural and functional analysis of tissues and cells with resolution and contrast unattainable by any other methods. However, the major challenges of many biophotonics techniques are associated with the need to enhance imaging resolution even further to the sub-cellular level as well as translate them for in vivo studies. The tissue optical clearing method uses immersion of tissues into optical clearing agents (OCAs) that reduces the scattering of tissue and makes tissue more transparent and this method has been successfully used ever since. This book is a self-contained introduction to tissue optical clearing, including the basic principles and in vitro biological applications, from in vitro to in vivo tissue optical clearing methods, and combination of tissue optical clearing and various optical imaging for diagnosis. The chapters cover a wide range of issues related to the field of tissue optical clearing: mechanisms of tissue optical clearing in vitro and in vivo; traditional and innovative optical clearing agents; recent achievements in optical clearing of different tissues (including pathological tissues) and blood for optical imaging diagnosis and therapy. This book provides a comprehensive account of the latest research and possibilities of utilising optical clearing as an instrument for improving the diagnostic effectiveness of modern optical diagnostic methods. The book is addressed to biophysicist researchers, graduate students and postdocs of biomedical specialties, as well as biomedical engineers and physicians interested in the development and application of optical methods in medicine. Key features: The first collective reference to collate all known knowledge on this topic Edited by experts in the field with chapter contributions from subject area specialists Brings together the two main approaches in immersion optical clearing into one cohesive book

Optical Methods and Instrumentation in Brain Imaging and Therapy

Author : Steen J. Madsen
Publisher : Springer Science & Business Media
Page : 284 pages
File Size : 42,9 Mb
Release : 2012-11-13
Category : Science
ISBN : 9781461449782

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Optical Methods and Instrumentation in Brain Imaging and Therapy by Steen J. Madsen Pdf

This book provides a comprehensive up-to-date review of optical approaches used in brain imaging and therapy. It covers a variety of imaging approaches including diffuse optical imaging, laser speckle imaging, photoacoustic imaging and optical coherence tomography. A number of laser-based therapeutic techniques are reviewed, including photodynamic therapy, fluorescence guided resection and photothermal therapy. Fundamental principles and instrumentation are discussed for each imaging and therapeutic approach.

Bioprinting in Regenerative Medicine

Author : Kursad Turksen
Publisher : Springer
Page : 140 pages
File Size : 45,7 Mb
Release : 2015-09-02
Category : Science
ISBN : 9783319213866

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Bioprinting in Regenerative Medicine by Kursad Turksen Pdf

This volume presents the current state of laser-assisted bioprinting, a cutting edge tissue engineering technology. Nineteen chapters discuss the most recent developments in using this technology for engineering different types of tissue. Beginning with an overview, the discussion covers bioprinting in cell viability and pattern viability, tissue microfabrication to study cell proliferation, microenvironment for controlling stem cell fate, cell differentiation, zigzag cellular tubes, cartilage tissue engineering, osteogenesis, vessel substitutes, skin tissue and much more. Because bioprinting is on its way to becoming a dominant technology in tissue-engineering, Bioprinting in Regenerative Medicine is essential reading for those researching or working in regenerative medicine, tissue engineering or translational research. Those studying or working with stem cells who are interested in the development of the field will also find the information invaluable.

Imaging in Stem Cell Transplant and Cell-based Therapy

Author : Tarun Pandey
Publisher : Humana
Page : 174 pages
File Size : 52,5 Mb
Release : 2018-08-12
Category : Science
ISBN : 331984752X

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Imaging in Stem Cell Transplant and Cell-based Therapy by Tarun Pandey Pdf

This book provides a review of imaging techniques and applications in stem cell transplantation and other cell-based therapies. The basis of different molecular imaging techniques is explained in detail, as is the current state of interventional radiology techniques. While the whole is a comprehensive discussion, each chapter is self-sufficient enough so that each can be reviewed independently. The contributors represent years of international and cross-disciplinary expertise and perspective and are all well known in their fields. comprehensive information on the role of clinical and molecular imaging in stem cell therapy from this book reviewed in detail. Essential reading for radiologists and physicians who are interested in developing a basic understanding of stem cell imaging and applications of stem cells and cell based therapies. However, it will also be of interest to clinical scientists and researchers alike, including those involved in stem cell labeling, tracking & imaging, cancer therapy, angiogenesis and cardiac regeneration.

An Introduction to Biomedical Optics

Author : Robert Splinter,Brett A. Hooper
Publisher : Taylor & Francis
Page : 632 pages
File Size : 48,9 Mb
Release : 2006-12-13
Category : Science
ISBN : 9781420011838

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An Introduction to Biomedical Optics by Robert Splinter,Brett A. Hooper Pdf

Many universities now offer a course in biomedical optics, but lack a textbook specifically addressing the topic. Intended to fill this gap, An Introduction to Biomedical Optics is the first comprehensive, introductory text describing both diagnostic and therapeutic optical methods in medicine. It provides the fundamental background needed for graduate students in biomedical and electrical engineering, physics, biology, and medicine to learn about several biomedical optics issues. The textbook is divided into three main sections: general optics theory, therapeutic applications of light, and diagnostic optical methods. Each chapter has different levels of detail to build students' knowledge from one level to the next. The first section covers the history of optics theory and the basic science behind light-tissue interactions. It also introduces the relevant approaches and approximations used to describe light propagation in turbid biological media. In the second section, the authors look more closely at light-tissue interactions and their applications in different medical areas, such as wound healing and tissue welding. The final section examines the various diagnostic methods that are employed using optical techniques. Throughout the text, the authors employ numerical examples of clinical and research requirements. Fulfilling the need for a concise biomedical optics textbook, An Introduction to Biomedical Optics addresses the theory and applications of this growing field.

Imaging in Cellular and Tissue Engineering

Author : Hanry Yu,Nur Aida Abdul Rahim
Publisher : CRC Press
Page : 296 pages
File Size : 40,8 Mb
Release : 2013-05-16
Category : Medical
ISBN : 9781439848036

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Imaging in Cellular and Tissue Engineering by Hanry Yu,Nur Aida Abdul Rahim Pdf

Details on specific imaging modalities for different cellular and tissue engineering applications are scattered throughout articles and chapters in the literature. Gathering this information into a single reference, Imaging in Cellular and Tissue Engineering presents both the fundamentals and state of the art in imaging methods, approaches, and applications in regenerative medicine. The book underscores the broadening scope of imaging applications in cellular and tissue engineering. It covers a wide range of optical and biological applications, including the repair or replacement of whole tissues (such as bone, cartilage, blood vessels, and bladder) and more novel artificially created support systems (such as artificial pancreas and bioartificial liver). Each chapter describes a particular application, relevant optical instrumentation, physical principles governing the imaging method, and strengths and weaknesses of the technique. The book also presents current and emerging data processing procedures. As the field of tissue engineering moves from creating simpler outer body parts to more sophisticated internal organs, researchers need to evaluate and control how well the tissues are engineered and integrated into the living body. Suitable for both experts and newcomers in bioengineering and biomedical imaging, this book shows researchers how to apply imaging techniques to next-generation engineered cells and tissues. It helps them assess the suitability of specific imaging modalities for applications with various functional requirements.

Stem Cells for Myocardial Regeneration

Author : Randall J. Lee
Publisher : Humana
Page : 267 pages
File Size : 40,7 Mb
Release : 2016-08-23
Category : Medical
ISBN : 1493961268

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Stem Cells for Myocardial Regeneration by Randall J. Lee Pdf

The feld of regenerative medicine is in its infancy state. Enthusiasm for the potential of organ regeneration lies with the potential pluripotency of stem cells to differentiate into various tissue types. This volume of Methods in Molecular Biology will focus on the use of stem cells for myocardial repair and regeneration. The emphasis of this issue will be to provide basic scientists, translational investigators, and cardiologists a means to evaluate the effcacy and safety of stem cells in a standardized fashion for myocardial regeneration. Many different cell types have been considered for myocardial repair. Adult card- myocytes are unable to survive even when transplanted into normal myocardium. The use of fetal or neonatal cardiomyocytes is not a feasible source of cells due to ethical concerns and donor availability. Therefore, the use of pluripotent stem cells has become the focus of a cell source for myocardial repair and regeneration. A variety of stem cell types have been suggested to participate in myocardial repair. This has led the investigators to search for the “optimal cell type for myocardial repair”. Reliable isolation of the cell source with the ability to expand the cell population is a prerequisite. In the frst section of this book, methods for isolation of commonly used stem cells being investigated for myocardial regeneration are presented. Once a stem cell source has been selected, the stem cell needs to be tested in an app- priate animal model before being translated into clinical practice.

Proceedings of Light-Activated Tissue Regeneration and Therapy Conference

Author : Ronald Waynant,Darrell B. Tata
Publisher : Springer Science & Business Media
Page : 446 pages
File Size : 46,5 Mb
Release : 2008-09-11
Category : Science
ISBN : 9780387718095

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Proceedings of Light-Activated Tissue Regeneration and Therapy Conference by Ronald Waynant,Darrell B. Tata Pdf

This book is the first to present the mechanism which explains why light is an effective treatment for so many illnesses and diseases. The book not only explains this mechanism, but describes uses for the mechanism, as well as what new work is planned and what changes will be seen in FDA regulations. Extensive papers and coverage on many interesting topics are included.

Magnetic Resonance Imaging in Tissue Engineering

Author : Mrignayani Kotecha,Richard L. Magin,Jeremy J. Mao
Publisher : John Wiley & Sons
Page : 444 pages
File Size : 42,7 Mb
Release : 2017-03-06
Category : Technology & Engineering
ISBN : 9781119193357

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Magnetic Resonance Imaging in Tissue Engineering by Mrignayani Kotecha,Richard L. Magin,Jeremy J. Mao Pdf

Magnetic Resonance Imaging in Tissue Engineering provides a unique overview of the field of non-invasive MRI assessment of tissue engineering and regenerative medicine Establish a dialogue between the tissue-engineering scientists and imaging experts and serves as a guide for tissue engineers and biomaterial developers alike Provides comprehensive details of magnetic resonance imaging (MRI) techniques used to assess a variety of engineered and regenerating tissues and organs Covers cell-based therapies, engineered cartilage, bone, meniscus, tendon, ligaments, cardiovascular, liver and bladder tissue engineering and regeneration assessed by MRI Includes a chapter on oxygen imaging method that predominantly is used for assessing hypoxia in solid tumors for improving radiation therapy but has the ability to provide information on design strategies and cellular viability in tissue engineering regenerative medicine

Advanced High-Resolution Tomography in Regenerative Medicine

Author : Alessandra Giuliani,Alessia Cedola
Publisher : Springer
Page : 232 pages
File Size : 42,9 Mb
Release : 2018-11-19
Category : Science
ISBN : 9783030003685

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Advanced High-Resolution Tomography in Regenerative Medicine by Alessandra Giuliani,Alessia Cedola Pdf

This book covers the state-of-the-art research on advanced high-resolution tomography, exploring its role in regenerative medicine. and also explores the 3D interactions between tissues, cells, and biomaterials. Various multidisciplinary paths in regenerative medicine are covered, including X-ray microtomography and its role in regenerative medicine, synchrotron radiation-based microtomography and phase contrast tomography, the challenge of the vascularization of regenerated tissues, lung and cartilage imaging, and more. This is an ideal book for biomedical engineers, biologists, physicists, clinicians, and students who want to pursue their studies in the field of regenerative medicine. This book also: Reviews in detail the algorithms and software used for the 3D exploration of regenerated tissue Covers the latest research on the use of X-ray microtomography for muscle diseases Details applications of synchrotron radiation tomography in orthopedics and dentistry

Multiscale Fabrication of Functional Materials for Regenerative Medicine

Author : Michele Bianchi
Publisher : Springer Science & Business Media
Page : 92 pages
File Size : 41,8 Mb
Release : 2011-08-31
Category : Technology & Engineering
ISBN : 364222881X

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Multiscale Fabrication of Functional Materials for Regenerative Medicine by Michele Bianchi Pdf

Regenerative medicine demands new concepts and fabrication tools to improve our common knowledge about cell-cell and cell-environment interactions. In this work, Michele Bianchi shows that different kinds of signals, such as chemical, topographical, and electrical signals, can be arranged in a highly-controlled way. Furthermore, Michele uses scale lengths ranging from several micrometers to a few nanometers, through the employment of unconventional fabrication techniques. For each signal, Michele chose properly designed materials and fabrication methods. The external signals are capable of controlling cell adhesion and growth, opening the way for a systematic investigation of the environmental features affecting cell behaviour.