Osteochondral Tissue Engineering

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Osteochondral Tissue Engineering

J. Miguel Oliveira,Sandra Pina,Rui L. Reis,Julio San Roman
Osteochondral Tissue Engineering Book PDF

Author : J. Miguel Oliveira,Sandra Pina,Rui L. Reis,Julio San Roman
Publisher : Springer
Page : 511 pages
File Size : 48,8 Mb
Release : 2018-05-07
Category : Science
ISBN : 9783319767352

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Osteochondral Tissue Engineering by J. Miguel Oliveira,Sandra Pina,Rui L. Reis,Julio San Roman Pdf

This book covers the most recent developments in the field of osteochondral tissue engineering (OCTE) and covers in detail the concepts and current challenges for bone and cartilage repair and regeneration. Specific topics include viscosupplementation, biologicals, tissue engineering approaches, in vitro and in vivo models, and technological advances with stem cells, bioreactors, and microfluidics. Osteochondral Tissue Engineering: Challenges, Current Strategies, and Technological Advances presents challenges and strategies in the field of osteochondral regeneration and serves as a core reference for biomedical engineering students and a wide range of established researchers and professionals working in orthopedics.

Osteochondral Tissue Engineering

J. Miguel Oliveira,Sandra Pina,Rui L. Reis,Julio San Roman
Osteochondral Tissue Engineering Book PDF

Author : J. Miguel Oliveira,Sandra Pina,Rui L. Reis,Julio San Roman
Publisher : Springer
Page : 438 pages
File Size : 55,9 Mb
Release : 2018-04-24
Category : Science
ISBN : 9783319767116

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Osteochondral Tissue Engineering by J. Miguel Oliveira,Sandra Pina,Rui L. Reis,Julio San Roman Pdf

This book reviews the most recent developments in the field of osteochondral tissue engineering (OCTE) and presents challenges and strategies being developed that face not only bone and cartilage regeneration, but also establish osteochondral interface formation in order to translate it into a clinical setting. Topics include nanotechnology approaches and biomaterials advances in osteochondral engineering, advanced processing methodology, as well as scaffolding and surface engineering strategies in OCTE. Hydrogel systems for osteochondral applications are also detailed thoroughly. Osteochondral Tissue Engineering: Nanotechnology, Scaffolding-Related Developments and Translation is an ideal book for biomedical engineering students and a wide range of established researchers and professionals working in the orthopedic field.

Articular Cartilage Tissue Engineering

Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu
Articular Cartilage Tissue Engineering Book PDF

Author : Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu
Publisher : Morgan & Claypool Publishers
Page : 183 pages
File Size : 52,9 Mb
Release : 2010
Category : Medical
ISBN : 9781598298758

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Articular Cartilage Tissue Engineering by Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu Pdf

Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage's low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analysis on the United States Food and Drug Administration regulatory pathways that products must follow to market. This book was written to serve as a reference for researchers seeking to learn about articular cartilage, for undergraduate and graduate level courses, and as a compendium of articular cartilage tissue engineering design criteria. Table of Contents: Hyaline Articular Cartilage / Cartilage Aging and Pathology / In Vitro / Bioreactors / Future Directions

Innovative Materials and Techniques for Osteochondral Repair

Horea Rareș Ciprian Benea
Innovative Materials and Techniques for Osteochondral Repair Book PDF

Author : Horea Rareș Ciprian Benea
Publisher : Materials Research Forum LLC
Page : 184 pages
File Size : 49,6 Mb
Release : 2019-11-25
Category : Technology & Engineering
ISBN : 9781644900536

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Innovative Materials and Techniques for Osteochondral Repair by Horea Rareș Ciprian Benea Pdf

The book presents research in treating focal joint cartilage defects. Lipoaspirate fluid (LAF) cells have important applications in such areas as orthopedics, general surgery, plastic and repair or vascular surgery. Also discussed are cartilage tissue regeneration therapies using collagen scaffolds and multipotent mesenchymal cells; this offers the possibility of making real "biological arthroplasties". The regeneration of cartilage tissue by injecting stem cell concentrates gives hope to patients suffering from cartilage degradation. Keywords: Biomaterials, Osteochondral Repair, Lipoaspirate Fluid (LAF) Cells, Arthrosis, Focal Joint Cartilage Defects, Physiopathology of Cartilage Lesions, Diagnosis of Cartilage Lesions, Treatment of Cartilage Lesions, Plastic Surgery, Vascular Surgery, Repair Surgery, Orthopedics, Biological Arthroplasties.

Tissue Engineering for Artificial Organs, 2 Volume Set

Anwarul Hasan
Tissue Engineering for Artificial Organs 2 Volume Set Book PDF

Author : Anwarul Hasan
Publisher : John Wiley & Sons
Page : 762 pages
File Size : 55,7 Mb
Release : 2017-06-19
Category : Science
ISBN : 9783527338634

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Tissue Engineering for Artificial Organs, 2 Volume Set by Anwarul Hasan Pdf

A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.

The Soft–Hard Tissue Junction

Neil D. Broom,Ashvin Thambyah
The Soft Hard Tissue Junction Book PDF

Author : Neil D. Broom,Ashvin Thambyah
Publisher : Cambridge University Press
Page : 403 pages
File Size : 52,7 Mb
Release : 2018-11-29
Category : Technology & Engineering
ISBN : 9781107137868

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The Soft–Hard Tissue Junction by Neil D. Broom,Ashvin Thambyah Pdf

Discover how the detailed structures of musculoskeletal tissue junctions relate to their mechanical function. This pioneering book, richly illustrated with tissue images, offers a rigorous, biomechanical approach to understanding the soft-hard tissue interface across multiple scales of resolution.

Cartilage Tissue Engineering and Regeneration Techniques

Dimitrios D. Nikolopoulos,George K. Safos,Kalpaxis Dimitrios
Cartilage Tissue Engineering and Regeneration Techniques Book PDF

Author : Dimitrios D. Nikolopoulos,George K. Safos,Kalpaxis Dimitrios
Publisher : BoD – Books on Demand
Page : 160 pages
File Size : 41,5 Mb
Release : 2019-06-05
Category : Technology & Engineering
ISBN : 9781789238495

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Cartilage Tissue Engineering and Regeneration Techniques by Dimitrios D. Nikolopoulos,George K. Safos,Kalpaxis Dimitrios Pdf

Osteochondral defects can be challenging to treat, first, because the damaged articular cartilage has a poor intrinsic reparative capability, and second, because these defects cause chronic pain and serious disability. That is why cartilage repair remains one of the most challenging issues of musculoskeletal medicine. Arthroscopic and open techniques that have been developed over the last two decades intend to promote the success of complete repair of the articular cartilage defects; nevertheless, these therapies cannot always offer 100% success. Nowadays, cartilage tissue engineering is an emerging technique for the regeneration of cartilage tissue. Taking into consideration these perspectives, this book aims to present a summary of cartilage tissue engineering, including development, recent progress, and major steps taken toward the regeneration of functional cartilage tissue. Special emphasis is placed on the role of stimulating factors, including growth factors, gene therapies, as well as scaffolds, including natural, synthetic, and nanostructured.

Scaffolding In Tissue Engineering

Peter X. Ma,Jennifer Elisseeff
Scaffolding In Tissue Engineering Book PDF

Author : Peter X. Ma,Jennifer Elisseeff
Publisher : CRC Press
Page : 656 pages
File Size : 49,5 Mb
Release : 2005-08-19
Category : Medical
ISBN : 9781420027563

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Scaffolding In Tissue Engineering by Peter X. Ma,Jennifer Elisseeff Pdf

The growing interest in scaffolding design and increasing research programs dedicated to regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While certain books and journal articles address various aspects in the field, this is the first current, comprehensive text focusing on scaffolding for tissue engineering.

Tissue Engineering III: Cell - Surface Interactions for Tissue Culture

Cornelia Kasper,Frank Witte,Ralf Pörtner
Tissue Engineering III Cell Surface Interactions for Tissue Culture Book PDF

Author : Cornelia Kasper,Frank Witte,Ralf Pörtner
Publisher : Springer
Page : 342 pages
File Size : 49,6 Mb
Release : 2012-04-23
Category : Science
ISBN : 9783642282829

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Tissue Engineering III: Cell - Surface Interactions for Tissue Culture by Cornelia Kasper,Frank Witte,Ralf Pörtner Pdf

The Cell-Surface Interaction, by J. S. Hayes, E. M. Czekanska and R. G. Richards. Studying Cell-Surface Interactions In Vitro: A Survey of Experimental Approaches and Techniques, by Stefanie Michaelis, Rudolf Robelek and Joachim Wegener. Harnessing Cell-Biomaterial Interactions for Osteochondral Tissue Regeneration, by Kyobum Kim, Diana M. Yoon, Antonios G. Mikos and F. Kurtis Kasper. Interaction of Cells with Decellularized Biological Materials, by Mathias Wilhelmi, Bettina Giere and Michael Harder. Evaluation of Biocompatibility Using In Vitro Methods: Interpretation and Limitations, by Arie Bruinink and Reto Luginbuehl. Artificial Scaffolds and Mesenchymal Stem Cells for Hard Tissues, by Margit Schulze and Edda Tobiasch. Bioactive Glass-Based Scaffolds for Bone Tissue Engineering, by Julia Will, Lutz-Christian Gerhardt and Aldo R. Boccaccini. Microenvironment Design for Stem Cell Fate Determination, by Tali Re’em and Smadar Cohen. Stem Cell Differentiation Depending on Different Surfaces, by Sonja Kress, Anne Neumann, Birgit Weyand and Cornelia Kasper. Designing the Biocompatibility of Biohybrids, by Frank Witte, Ivonne Bartsch and Elmar Willbold. Interaction of Cartilage and Ceramic Matrix, by K. Wiegandt, C. Goepfert, R. Pörtner and R. Janssen. Bioresorption and Degradation of Biomaterials, by Debarun Das, Ziyang Zhang, Thomas Winkler, Meenakshi Mour, Christina I. Günter, Michael M. Morlock, Hans-Günther Machens and Arndt F. Schilling.

Cartilage Tissue Engineering and Regeneration Techniques

Kalpaxis Dimitrios,George K. Safos,Dimitrios D. Nikolopoulos
Cartilage Tissue Engineering and Regeneration Techniques Book PDF

Author : Kalpaxis Dimitrios,George K. Safos,Dimitrios D. Nikolopoulos
Publisher : Unknown
Page : 158 pages
File Size : 41,5 Mb
Release : 2019
Category : Medicine (General)
ISBN : 1838807810

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Cartilage Tissue Engineering and Regeneration Techniques by Kalpaxis Dimitrios,George K. Safos,Dimitrios D. Nikolopoulos Pdf

Osteochondral defects can be challenging to treat, first, because the damaged articular cartilage has a poor intrinsic reparative capability, and second, because these defects cause chronic pain and serious disability. That is why cartilage repair remains one of the most challenging issues of musculoskeletal medicine. Arthroscopic and open techniques that have been developed over the last two decades intend to promote the success of complete repair of the articular cartilage defects; nevertheless, these therapies cannot always offer 100% success. Nowadays, cartilage tissue engineering is an emerging technique for the regeneration of cartilage tissue. Taking into consideration these perspectives, this book aims to present a summary of cartilage tissue engineering, including development, recent progress, and major steps taken toward the regeneration of functional cartilage tissue. Special emphasis is placed on the role of stimulating factors, including growth factors, gene therapies, as well as scaffolds, including natural, synthetic, and nanostructured.

Tissue Engineering of Cartilage and Bone

Gregory R. Bock,Jamie A. Goode
Tissue Engineering of Cartilage and Bone Book PDF

Author : Gregory R. Bock,Jamie A. Goode
Publisher : John Wiley & Sons
Page : 262 pages
File Size : 42,5 Mb
Release : 2003-07-22
Category : Medical
ISBN : 9780470864234

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Tissue Engineering of Cartilage and Bone by Gregory R. Bock,Jamie A. Goode Pdf

Tissue engineering takes advantages of the combined use of cultured living cells and three-dimensional scaffolds to reconstruct adult tissues that are absent or malfunctioning. This book brings together scientists and clinicians working on a variety of approaches for regenerating of damaged or lost cartilage and bone to assess the progress of this dynamic field. In its early days, tissue engineering was driven by material scientists who designed novel bio-resorbable scaffolds on which to seed cells and grow tissues. This ground-breaking work generated high expectations, but there have been significant stumbling blocks holding back the widespread use of these techniques in the clinic. These challenges, and potential ways of overcoming them, are given thorough coverage in the discussions that follow each chapter. The key questions addressed in this book include the following. How good must cartilage repair be for it to be worthwhile? What is the best source of cells for tissue engineering of both bone and cartilage? Which are the most effective cell scaffolds? What are the best preclinical models for these technologies? And when it comes to clinical trials, what sort of outcome measures should be used? With contributions from some of the leading experts in this field, this timely publication will prove essential reading for anyone with an interest in the field of tissue engineering.

Cartilage Tissue Engineering

Martin J. Stoddart,Elena Della Bella,Angela R. Armiento
Cartilage Tissue Engineering Book PDF

Author : Martin J. Stoddart,Elena Della Bella,Angela R. Armiento
Publisher : Springer Nature
Page : 392 pages
File Size : 41,5 Mb
Release : 2022-11-10
Category : Science
ISBN : 9781071628393

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Cartilage Tissue Engineering by Martin J. Stoddart,Elena Della Bella,Angela R. Armiento Pdf

This detailed book brings together a collection of methodologies, from the most basic to the more complex, that provides researchers with a platform they can use to embark on a cartilage research career. To aid in the search for novel therapies for cartilage regeneration, this volume addresses 3D cartilage models, challenges associated with RNA and protein extraction, imaging, gene transfer, as well as stable differentiation and variations in cell phenotype from different tissue origins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Cartilage Tissue Engineering serves as an ideal guide for researchers working to advance the vital study of cartilage biology and repair.

Regenerative Engineering of Musculoskeletal Tissues and Interfaces

Syam Nukavarapu,Joseph Freeman,Cato Laurencin
Regenerative Engineering of Musculoskeletal Tissues and Interfaces Book PDF

Author : Syam Nukavarapu,Joseph Freeman,Cato Laurencin
Publisher : Woodhead Publishing
Page : 462 pages
File Size : 41,8 Mb
Release : 2015-04-24
Category : Technology & Engineering
ISBN : 9781782423140

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Regenerative Engineering of Musculoskeletal Tissues and Interfaces by Syam Nukavarapu,Joseph Freeman,Cato Laurencin Pdf

Repair and regeneration of musculoskeletal tissues is generating substantial interest within the biomedical community. Consequently, these are the most researched tissues from the regeneration point of view. Regenerative Engineering of Musculoskeletal Tissues and Interfaces presents information on the fundamentals, progress and recent developments related to the repair and regeneration of musculoskeletal tissues and interfaces. This comprehensive review looks at individual tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of cells, growth factors, and mechanical forces, moving on to discuss tissue-engineering strategies for bone, tendon, ligament, cartilage, meniscus, and muscle, as well as progress and advances in tissue vascularization and nerve innervation of the individual tissues. Final chapters present information on musculoskeletal tissue interfaces. Comprehensive review of the repair and regeneration of musculoskeletal individual tissues and tissue interfaces Presents recent developments, fundamentals and progress in the field of engineering tissues Reviews progress and advances in tissue vascularization and innervation

Regenerative Strategies for the Treatment of Knee Joint Disabilities

Joaquim Miguel Oliveira,Rui Luís Reis
Regenerative Strategies for the Treatment of Knee Joint Disabilities Book PDF

Author : Joaquim Miguel Oliveira,Rui Luís Reis
Publisher : Springer
Page : 411 pages
File Size : 54,5 Mb
Release : 2016-09-26
Category : Technology & Engineering
ISBN : 9783319447858

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Regenerative Strategies for the Treatment of Knee Joint Disabilities by Joaquim Miguel Oliveira,Rui Luís Reis Pdf

This book presents regenerative strategies for the treatment of knee joint disabilities. The book is composed of four main sections totaling 19 chapters which review the current knowledge on the clinical management and preclinical regenerative strategies. It examines the role of different natural-based biomaterials as scaffolds and implants for addressing different tissue lesions in the knee joint. Section one provides an updated and comprehensive discussion on articular cartilage tissue regeneration. Section two focuses on the important contributions for bone and osteochondral tissue engineering. Section three overview the recent advances on meniscus repair/regeneration strategies. Finally, section four further discusses the current strategies for treatment of ligament lesions. Each chapter is prepared by world know expert on their fields, so we do firmly believe that the proposed book will be a reference in the area of biomaterials for regenerative medicine.

Joint Function Preservation

Alberto Gobbi,John G. Lane,Umile Giuseppe Longo,Ignacio Dallo
Joint Function Preservation Book PDF

Author : Alberto Gobbi,John G. Lane,Umile Giuseppe Longo,Ignacio Dallo
Publisher : Springer Nature
Page : 394 pages
File Size : 54,6 Mb
Release : 2021-11-03
Category : Medical
ISBN : 9783030829582

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Joint Function Preservation by Alberto Gobbi,John G. Lane,Umile Giuseppe Longo,Ignacio Dallo Pdf

This user-friendly, pragmatic book discusses the normal and pathological conditions of the appendicular skeleton, with a focus on the preservation of joint function, providing a detailed overview of strategies for both common and complex joint preservation. The first section covers basic topics, ranging from joints homeostasis and biomechanics, to genetics, bio-orthopedics, tissue engineering and 3D bioprinting. The following sections are each dedicated to a specific joint – its functional anatomy, pathologic conditions, diagnostics and treatment. This book is of interest to orthopedists and sports medicine specialists treating common and complex injuries of the joints.