Oxygen Free Radicals In Tissue Damage

Author : TARR,M.,SAMSON,F.
Publisher : Springer Science & Business Media
Page : 306 pages
File Size : 44,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781461598404

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Oxygen Free Radicals in Tissue Damage by TARR,M.,SAMSON,F. Pdf

Oxygen free radicals and other reactive oxygen species are being postulated as causal agents in an increasing number of pathological conditions. Indeed, some investigators are suggesting that highly destructive reactive oxygen species are the final common path lead ing to tissue damage following a wide variety of insults including trauma, hypoxia, ischemia, hyperoxia, radiation, some toxins, and even strenuous athletic pursuits. But, as Robert Floyd points out, "Proof of the importance of oxygen free radicals and the oxidative damage they initiate depend on unequivocal evidence for the pres ence of free radicals and a clear association of their formation with the induction of the dysfunction of pathological conditions. " Since such proof does not come easily, there have been and will continue to be many controversies regarding the role played by reactive oxygen species in tissue damage. There have been many recent reviews of the chemistry and pos sible role of reactive oxygen species in many types of organ dys functions, tissue damage, degenerative diseases, and aging. This book is not such a review. Rather it presents for a diverse audience of physical-organic chemists, biochemists, medical researchers, and other investigators of pathophysiology, discussions of a variety of is sues important for understanding reactive oxygen species and their role in tissue damage.

Author : David W. FitzSimons
Publisher : John Wiley & Sons
Page : 432 pages
File Size : 49,5 Mb
Release : 2009-09-18
Category : Science
ISBN : 9780470715109

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Oxygen Free Radicals and Tissue Damage by David W. FitzSimons Pdf

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Author : Manfred Lamprecht
Publisher : CRC Press
Page : 304 pages
File Size : 49,5 Mb
Release : 2014-09-17
Category : Medical
ISBN : 9781466567573

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Antioxidants in Sport Nutrition by Manfred Lamprecht Pdf

The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.

Author : Symposium on Oxygen Free Radicals and Tissue Damage$ (1978 : Londres)
Publisher : Unknown
Page : 389 pages
File Size : 42,5 Mb
Release : 1979
Category : Electronic
ISBN : 0608162094

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Oxygen Free Radicals and Tissue Damage by Symposium on Oxygen Free Radicals and Tissue Damage$ (1978 : Londres) Pdf

Author : C.A. Rice-Evans,R.H. Burdon
Publisher : Elsevier
Page : 409 pages
File Size : 46,9 Mb
Release : 1994-02-09
Category : Science
ISBN : 9780080860886

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Free Radical Damage and its Control by C.A. Rice-Evans,R.H. Burdon Pdf

This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical scavenging drugs. Oxidative stress may be influenced by exogenous agents of oxidative stress, radiation, trauma, drug activation, oxygen excess, or by exogenous oxidative stress which is associated with many pathological states including chronic inflammatory disorders, cardiovascular disease, injury to the central nervous system, and connective tissue damage. This and many other such aspects are presented clearly and in depth. The development of antioxidant drugs depends on the understanding of the mechanisms underlying the generation of excessive free radicals in vivo, the factors controlling their release and the site of their action. This excellent volume presents an up-to-date account of the current state of knowledge in these areas.

Author : Mary Treinen Moslen,Charles V. Smith
Publisher : CRC Press
Page : 238 pages
File Size : 47,9 Mb
Release : 1992-02-21
Category : Science
ISBN : 0849351618

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Free Radical Mechanisms of Tissue Injury by Mary Treinen Moslen,Charles V. Smith Pdf

This timely volume describes the contributions of free radicals and reactive oxygen species to disease processes in a variety of tissues. Topics include the roles of lipid peroxide-modified lipoproteins in atherosclerosis, peroxidation products in retinopathy, reactive oxygen species and neutrophils in mycardial ischemia-reflow injury, iron and reactive oxygen species in hemoglobin-mediated CNS damage and in asbestos-mediated lung injury. Critical reviews examine the evidence for radical species in ethanol-induced liver injury and in muscular dystrophy. The wealth of new information presented makes this book valuable for teaching and an important reference volume for researchers exploring problems in human disease.

Author : Trevor Frank Slater
Publisher : Unknown
Page : 304 pages
File Size : 41,6 Mb
Release : 1972
Category : Medical
ISBN : UOM:39015000304728

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Free Radical Mechanisms in Tissue Injury by Trevor Frank Slater Pdf

Author : Anonim
Publisher : Unknown
Page : 244 pages
File Size : 44,9 Mb
Release : 1994
Category : Active oxygen
ISBN : IND:30000143535577

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Oxygen Radicals and Lung Injury by Anonim Pdf

Author : Val Vallyathan,Vince Castranova,Xianglin Shi
Publisher : Springer Science & Business Media
Page : 393 pages
File Size : 53,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461510871

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Oxygen/Nitrogen Radicals: Cell Injury and Disease by Val Vallyathan,Vince Castranova,Xianglin Shi Pdf

A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.

Author : Toshiki Asao,Md Asaduzzaman
Publisher : BoD – Books on Demand
Page : 220 pages
File Size : 55,8 Mb
Release : 2018-11-07
Category : Science
ISBN : 9781789843774

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Phytochemicals by Toshiki Asao,Md Asaduzzaman Pdf

Phytochemicals provides original research work and reviews on the sources of phytochemicals, and their roles in disease prevention, supplementation, and accumulation in fruits and vegetables. The roles of anthocyanin, flavonoids, carotenoids, and taxol are presented in separate chapters. Antioxidative and free radicle scavenging activity of phytochemicals is also discussed. The medicinal properties of Opuntia, soybean, sea buckthorn, and gooseberry are presented in a number of chapters. Supplementation of plant extract with phytochemical properties in broiler meals is discussed in one chapter. The final two chapters include the impact of agricultural practices and novel processing technologies on the accumulation of phytochemicals in fruits and vegetables. This book mainly focuses on medicinal plants and the disease-preventing properties of phytochemicals, which will be a useful resource to the reader.

Author : Craig Thomas
Publisher : CRC Press
Page : 304 pages
File Size : 40,5 Mb
Release : 1998-03-18
Category : Medical
ISBN : 9057022265

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Oxygen Radicals and the Disease Process by Craig Thomas Pdf

This book provides a detailed investigation into the evidence implicating oxygen radicals in the etiology of eleven different human diseases or conditions. World renowned experts from each discipline review the data supporting this involvement, and discuss the full implications that result. Topics covered include Alzheimer's disease, cerebral ischemia, rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, ARDS, critical care medicine and cancer. This book not only provides an invaluable resource for those seeking up to date information on the evidence supporting the involvement of oxygen radicals in human disease, but also instigates theoretical discussion of future research endeavors.

Author : Natan Gadoth,Hans Hilmar Göbel
Publisher : Springer Science & Business Media
Page : 323 pages
File Size : 43,6 Mb
Release : 2010-11-19
Category : Medical
ISBN : 9781603275149

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Oxidative Stress and Free Radical Damage in Neurology by Natan Gadoth,Hans Hilmar Göbel Pdf

The role of free radicals and oxidative stress in neurological disorders has only recently been recognized, leaving clinical neurologists to seek in vain for information on the subject even in major textbooks. What published information there is may consist of brief reminders of the possible association of superoxidase dismutase with familial amyotrophic lateral sclerosis and nitrous oxide with migraine. With luck they may also find information on the purported role of free radicals in the pathogenesis of traumatic brain injury. Oxidative Stress and Free Radical Damage in Neurology sets the record straight, focusing on clinical and research issues regarding the interplay of free radicals and the human nervous system. Crucially, the chapters cover numerous antioxidants and their possible therapeutic role in neurological disorders. Key illnesses such as epilepsy, multiple sclerosis and Parkinson’s are analyzed, and chapters also examine more general issues such as the link between free radicals and inflammation of the central nervous system. Clinicians and laboratory researchers alike will find that this book augments their understanding not only of the widespread involvement of free radicals in the central nervous system but also of some uncertainties surrounding whether free radical damage in neurology plays a primary or secondary role.

Author : Barry Halliwell
Publisher : Unknown
Page : 160 pages
File Size : 47,6 Mb
Release : 1988
Category : Active oxygen in the body
ISBN : UOM:39015061005263

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Oxygen Radicals and Tissue Injury by Barry Halliwell Pdf

Author : Michael Simic
Publisher : Springer Science & Business Media
Page : 1064 pages
File Size : 50,9 Mb
Release : 2013-03-09
Category : Science
ISBN : 9781468455687

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Oxygen Radicals in Biology and Medicine by Michael Simic Pdf

This book is based on the papers presented at the "Fourth International Congress on Oxygen Radicals (4-ICOR)," held June 27 - July 3, 1987, at the University of California, La Jolla. The chapters deal with the phenomena associated with highly reactive oxygen species (hydroxy, peroxy, alkoxy, aroxy, and superoxide radicals, as well as singlet oxygen) and their peroxidation products (hydrogen peroxide, hydroperoxides, peroxides, and epoxides) as they relate to the fields of chemistry, food technology, nutrition, biology, pharmacology, and medicine. The kinetics, energetics, and mechanistic aspects of the reactions of these species and the interrelationship of oxygen radicals (or any other free radicals) and peroxidized products have been emphasized. Special attention is focused on the mechanisms of the generation of free radicals and peroxy products in biosystems and on the adverse effects of these radicals and products in humans. The topics span the continuum from the simple chemistry of model systems to the complex considerations of clinical medicine. The book also explores the mechanisms of agents that protect against free radicals and peroxy products in vitro and in vivo. These agents include antioxidants used in materials, food antioxidants, physiological antioxidants, and antioxienzymes (SOD, glutathione peroxidase, and catalases). The use of these inhibitors to prevent damage to organs being prepared for transplantation, thereby maintaining the quality of transplanted organs and/or extending their "shelf-life," also is examined.

Author : Barry Halliwell,John M. C. Gutteridge
Publisher : Oxford University Press, USA
Page : 568 pages
File Size : 43,8 Mb
Release : 1989
Category : Biochemistry
ISBN : UCSC:32106009290187

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Free Radicals in Biology and Medicine by Barry Halliwell,John M. C. Gutteridge Pdf

"This latest edition has been comprehensively rewritten and updated (over 80% of the text is new), whilst maintaining the clarity of its predecessor. There is expanded coverage of isoprostanes and related compounds, mechanisms of oxidative damage to DNA and proteins (and the repair of such damage), the free radical theory of ageing and the roles played by reactive species in signal transduction, cell death, human reproduction, and other important biological events. Greater emphasis has also been placed on the methods available to measure reactive species and oxidative damage (and their potential pitfalls), as well as the importance of antioxidants in the human diet." "This book is recommended as a comprehensive introduction to the field for students, clinicians and researchers, and an invaluable companion to all those interested in the role of free radicals in the life and medical sciences."--BOOK JACKET.