Oxygen Radicals And Lung Injury

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Oxygen Radicals and Lung Injury

Author : Anonim
Publisher : Unknown
Page : 244 pages
File Size : 52,8 Mb
Release : 1994
Category : Active oxygen
ISBN : IND:30000143535577

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Oxygen Radicals and Lung Injury by Anonim Pdf

Oxygen/Nitrogen Radicals

Author : Val Vallyathan,Vincent Castranova,Xianglin Shi
Publisher : CRC Press
Page : 550 pages
File Size : 42,5 Mb
Release : 2004-04-14
Category : Medical
ISBN : 0824748743

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Oxygen/Nitrogen Radicals by Val Vallyathan,Vincent Castranova,Xianglin Shi Pdf

The first state-of-the-art book dealing specifically with lung injury induced by oxygen and nitrogen radicals, this detailed treatise discusses molecular, cellular, and mechanistic events leading to pathophysiological outcomes; the role of oxidant species in the induction of these events; and potential therapeutic avenues targeting such molecular pathways. Important issues regarding oxidative stress involvement in the initiation and progression of pulmonary diseases-including diseases caused by occupational and environmental inhalation of toxicants-are discussed in the context of amelioration by antioxidants.

Oxygen/Nitrogen Radicals: Cell Injury and Disease

Author : Val Vallyathan,Vince Castranova,Xianglin Shi
Publisher : Springer Science & Business Media
Page : 393 pages
File Size : 55,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461510871

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Oxygen/Nitrogen Radicals: Cell Injury and Disease by Val Vallyathan,Vince Castranova,Xianglin Shi Pdf

A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.

Oxygen/nitrogen Radicals and Cellular Injury

Author : Kenneth B. Adler,Robert D. Devlin,Val Vallyathan
Publisher : Unknown
Page : 160 pages
File Size : 41,6 Mb
Release : 1998
Category : Antioxidants
ISBN : IND:30000143536013

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Oxygen/nitrogen Radicals and Cellular Injury by Kenneth B. Adler,Robert D. Devlin,Val Vallyathan Pdf

Oxidative Stress in Lung Diseases

Author : Sajal Chakraborti,Tapati Chakraborti,Salil Kumar Das,Dhrubajyoti Chattopadhyay
Publisher : Springer Nature
Page : 491 pages
File Size : 44,5 Mb
Release : 2019-08-31
Category : Science
ISBN : 9789811384134

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Oxidative Stress in Lung Diseases by Sajal Chakraborti,Tapati Chakraborti,Salil Kumar Das,Dhrubajyoti Chattopadhyay Pdf

This first volume of the comprehensive, two-volume work on oxidative stress in lung disease introduces the molecular mechanisms, and the role of oxidants in the progression of different lung diseases. The lungs of humans and animals are under constant threat from oxidants from either endogenous (e.g. in situ metabolic reactions) or exogenous sources (e.g. air pollutants). Further, oxidative stress causes the oxidation of proteins, DNA and lipids, which in turn generates secondary metabolic products. The book consists of sections, each focusing on different aspects of oxidant-mediated lung diseases. As such it is a unique reference resource for postgraduate students, biomedical researchers and also for the clinicians who are interested in studying and understanding oxidant-mediated lung diseases. The second volume will incorporate other aspects of oxidant-mediated lung diseases, including prevention and therapeutics.

Oxidative Stress in Lung Diseases

Author : Sajal Chakraborti,Narasimham L. Parinandi,Rita Ghosh,Nirmal K. Ganguly,Tapati Chakraborti
Publisher : Springer Nature
Page : 486 pages
File Size : 48,6 Mb
Release : 2019-11-23
Category : Science
ISBN : 9789813293663

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Oxidative Stress in Lung Diseases by Sajal Chakraborti,Narasimham L. Parinandi,Rita Ghosh,Nirmal K. Ganguly,Tapati Chakraborti Pdf

This is the second volume of the comprehensive, two-volume work on oxidative stress in lung diseases. Adopting a multidisciplinary approach, it demonstrates the cellular and molecular mechanisms associated with ROS (reactive oxygen species)-induced initiation and progression of a variety of lung diseases, such as COPD, emphysema, asthma, cystic fibrosis, occupational pulmonary diseases and pulmonary hypertension and discusses points for therapeutic intervention. The book also covers translational research and the latest research on prevention and therapeutics. Each chapter includes in-depth insights into the mechanisms associated with lung diseases and into identifying targets for drug development. Bridging the gap between fundamental and translational research, and examining applications in the biomedical and pharmaceutical industry, it is a thought- provoking read for basic and applied scientists engaged in biomedical research.

Oxygen/Nitrogen Radicals and Cellular Injury

Author : Kenneth B. Adler,Robert D. Devlin,Val Vallyathan
Publisher : DIANE Publishing
Page : 142 pages
File Size : 41,9 Mb
Release : 2000-03
Category : Electronic
ISBN : 9780788185380

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Oxygen/Nitrogen Radicals and Cellular Injury by Kenneth B. Adler,Robert D. Devlin,Val Vallyathan Pdf

Papers: characterization of inducible nitric oxide synthase expression in human airway epithelium; nitric oxide and its congeners in mitochondria; role of nitric oxide in inflammation and tissue injury during endotoxemia and hemorrhagic shock; nitric oxide and peroxynitrite production in ocular inflammation; 5 papers on pulmonary/pollutant effects; 6 papers on oxidants and signal transduction, including impact of oxidative stress on signal transduction control by phosphotyrosine phosphatases; the nature of antioxidant defense mechanisms; lipid peroxidation products and antioxidants in human disease; and lung injury and oxidoreductases.

Oxygen/Nitrogen Radicals

Author : Val Vallyathan
Publisher : Unknown
Page : 550 pages
File Size : 47,9 Mb
Release : 2004-04
Category : Electronic
ISBN : 0824754468

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Oxygen/Nitrogen Radicals by Val Vallyathan Pdf

Oxygen Radicals and the Disease Process

Author : Craig Thomas
Publisher : CRC Press
Page : 300 pages
File Size : 46,9 Mb
Release : 1998-03-18
Category : Medical
ISBN : 9057022273

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Oxygen Radicals and the Disease Process by Craig Thomas Pdf

This book provides a detailed investigation into the evidence implicating oxygen radicals in the etiology of eleven different human diseases or conditions. World renowned experts from each discipline review the data supporting this involvement, and discuss the full implications that result. Topics covered include Alzheimer's disease, cerebral ischemia, rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, ARDS, critical care medicine and cancer. This book not only provides an invaluable resource for those seeking up to date information on the evidence supporting the involvement of oxygen radicals in human disease, but also instigates theoretical discussion of future research endeavors.

Oxygen Free Radicals in Tissue Damage

Author : TARR,M.,SAMSON,F.
Publisher : Springer Science & Business Media
Page : 306 pages
File Size : 53,6 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781461598404

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Oxygen Free Radicals in Tissue Damage by TARR,M.,SAMSON,F. Pdf

Oxygen free radicals and other reactive oxygen species are being postulated as causal agents in an increasing number of pathological conditions. Indeed, some investigators are suggesting that highly destructive reactive oxygen species are the final common path lead ing to tissue damage following a wide variety of insults including trauma, hypoxia, ischemia, hyperoxia, radiation, some toxins, and even strenuous athletic pursuits. But, as Robert Floyd points out, "Proof of the importance of oxygen free radicals and the oxidative damage they initiate depend on unequivocal evidence for the pres ence of free radicals and a clear association of their formation with the induction of the dysfunction of pathological conditions. " Since such proof does not come easily, there have been and will continue to be many controversies regarding the role played by reactive oxygen species in tissue damage. There have been many recent reviews of the chemistry and pos sible role of reactive oxygen species in many types of organ dys functions, tissue damage, degenerative diseases, and aging. This book is not such a review. Rather it presents for a diverse audience of physical-organic chemists, biochemists, medical researchers, and other investigators of pathophysiology, discussions of a variety of is sues important for understanding reactive oxygen species and their role in tissue damage.

Oxygen Radicals and Tissue Injury

Author : Barry Halliwell
Publisher : Unknown
Page : 160 pages
File Size : 47,6 Mb
Release : 1988
Category : Active oxygen in the body
ISBN : UOM:39015061005263

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Oxygen Radicals and Tissue Injury by Barry Halliwell Pdf

Free Radical Mechanisms of Tissue Injury

Author : Mary Treinen Moslen,Charles V. Smith
Publisher : CRC Press
Page : 238 pages
File Size : 45,9 Mb
Release : 1992-02-21
Category : Science
ISBN : 0849351618

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Free Radical Mechanisms of Tissue Injury by Mary Treinen Moslen,Charles V. Smith Pdf

This timely volume describes the contributions of free radicals and reactive oxygen species to disease processes in a variety of tissues. Topics include the roles of lipid peroxide-modified lipoproteins in atherosclerosis, peroxidation products in retinopathy, reactive oxygen species and neutrophils in mycardial ischemia-reflow injury, iron and reactive oxygen species in hemoglobin-mediated CNS damage and in asbestos-mediated lung injury. Critical reviews examine the evidence for radical species in ethanol-induced liver injury and in muscular dystrophy. The wealth of new information presented makes this book valuable for teaching and an important reference volume for researchers exploring problems in human disease.

Oxyradicals in Medical Biology

Author : J.M. McCord
Publisher : Elsevier
Page : 188 pages
File Size : 42,9 Mb
Release : 1998-04-23
Category : Science
ISBN : 0080877109

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Oxyradicals in Medical Biology by J.M. McCord Pdf

The rapid expansion of the area of free radical biology in the last 25 years has occurred within a framework of assumptions and preconceived notions that has at times directed the course of this movement. The most dominant of these notions has been the view that free radical production is without exception a bad thing, and that the more efficient our elimination of these toxic substances, the better off we will be. The very important observation by Bernard Babior and colleagues in 1973 that activated phagocytes produce superoxide in order to kill micro organisms, served to illustrate that constructive roles are possible for free radicals. For many in the field, however, this merely underscored the deadly nature of oxygen-derived radicals, both from the microbe's point of view and from the host's as well. (Phagocyte-produced superoxide is responsible in part for the tissue injury manifested as inflammation. See Harris and Granger, Chapter 5, and Leff, Hybertson and Repine, Chapter 6.) Mother Nature, however, has a penchant for being able to make a silk purse from a sow's ear. If one is dealt a bad hand, one must simply make the best of it. After two decades of focusing on the destructive side of free radicals, the last few years have begun to reveal a new and finer perspective on free radical metabolism - a role in regulation of cellular function (see Schulze-Osthoff and Baeuerle, Chapter 2). Evidence from a number of sources suggests that an increase in the oxidative status of cell encourages that cell to grow and divide. Increasing the expression of mangnese superoxide dismutase can suppress the malignant phenotype of melanon cells (see Oberley and Oberley, Chapter 3). Oxidative stress beyond a certain poitosis (from the Greek, literally "to fall apart"). Is this suicide response an evolutionary fail-safe device to curtail tumorogenesis? Does oxidative stress-induced apoptosis account for the loss of immune cells in AIDS (see Flores and McCor Chapter 4)? This volume attempts to present the spectrum of roles, both good and bad played by active oxygen species as understood at this point in the evolution of this field of free radical biology.

Oxygen/nitrogen Radicals

Author : Anonim
Publisher : Unknown
Page : 409 pages
File Size : 55,5 Mb
Release : 2002
Category : Electronic
ISBN : OCLC:51022009

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Oxygen/nitrogen Radicals by Anonim Pdf

How Tobacco Smoke Causes Disease

Author : Anonim
Publisher : Unknown
Page : 728 pages
File Size : 41,8 Mb
Release : 2010
Category : Government publications
ISBN : UCSD:31822037817723

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How Tobacco Smoke Causes Disease by Anonim Pdf

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.