Oxygen Nitrogen Radicals And Cellular Injury

Author : Val Vallyathan,Vince Castranova,Xianglin Shi
Publisher : Springer Science & Business Media
Page : 393 pages
File Size : 51,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461510871

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Oxygen/Nitrogen Radicals: Cell Injury and Disease by Val Vallyathan,Vince Castranova,Xianglin Shi Pdf

A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.

Author : Kenneth B. Adler,Robert D. Devlin,Val Vallyathan
Publisher : DIANE Publishing
Page : 142 pages
File Size : 45,6 Mb
Release : 2000-03
Category : Electronic
ISBN : 9780788185380

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Oxygen/Nitrogen Radicals and Cellular Injury by Kenneth B. Adler,Robert D. Devlin,Val Vallyathan Pdf

Papers: characterization of inducible nitric oxide synthase expression in human airway epithelium; nitric oxide and its congeners in mitochondria; role of nitric oxide in inflammation and tissue injury during endotoxemia and hemorrhagic shock; nitric oxide and peroxynitrite production in ocular inflammation; 5 papers on pulmonary/pollutant effects; 6 papers on oxidants and signal transduction, including impact of oxidative stress on signal transduction control by phosphotyrosine phosphatases; the nature of antioxidant defense mechanisms; lipid peroxidation products and antioxidants in human disease; and lung injury and oxidoreductases.

Author : Kenneth B. Adler,Robert D. Devlin,Val Vallyathan
Publisher : Unknown
Page : 160 pages
File Size : 53,7 Mb
Release : 1998
Category : Antioxidants
ISBN : IND:30000143536013

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Oxygen/nitrogen Radicals and Cellular Injury by Kenneth B. Adler,Robert D. Devlin,Val Vallyathan Pdf

Author : Anonim
Publisher : Unknown
Page : 244 pages
File Size : 49,8 Mb
Release : 1994
Category : Active oxygen
ISBN : IND:30000143535577

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Oxygen Radicals and Lung Injury by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 409 pages
File Size : 49,7 Mb
Release : 2002
Category : Electronic
ISBN : OCLC:51022009

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Oxygen/nitrogen Radicals by Anonim Pdf

Author : Val Vallyathan,Vincent Castranova,Xianglin Shi
Publisher : CRC Press
Page : 550 pages
File Size : 50,7 Mb
Release : 2004-04-14
Category : Medical
ISBN : 0824748743

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Oxygen/Nitrogen Radicals by Val Vallyathan,Vincent Castranova,Xianglin Shi Pdf

The first state-of-the-art book dealing specifically with lung injury induced by oxygen and nitrogen radicals, this detailed treatise discusses molecular, cellular, and mechanistic events leading to pathophysiological outcomes; the role of oxidant species in the induction of these events; and potential therapeutic avenues targeting such molecular pathways. Important issues regarding oxidative stress involvement in the initiation and progression of pulmonary diseases-including diseases caused by occupational and environmental inhalation of toxicants-are discussed in the context of amelioration by antioxidants.

Author : Kenneth B. Adler
Publisher : Unknown
Page : 142 pages
File Size : 50,8 Mb
Release : 1998
Category : Electronic
ISBN : OCLC:214956039

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Oxygen Nitrogen Radicals and Cellular Injury by Kenneth B. Adler Pdf

Author : Mary Treinen Moslen,Charles V. Smith
Publisher : CRC Press
Page : 238 pages
File Size : 45,5 Mb
Release : 1992-02-21
Category : Science
ISBN : 0849351618

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Free Radical Mechanisms of Tissue Injury by Mary Treinen Moslen,Charles V. Smith Pdf

This timely volume describes the contributions of free radicals and reactive oxygen species to disease processes in a variety of tissues. Topics include the roles of lipid peroxide-modified lipoproteins in atherosclerosis, peroxidation products in retinopathy, reactive oxygen species and neutrophils in mycardial ischemia-reflow injury, iron and reactive oxygen species in hemoglobin-mediated CNS damage and in asbestos-mediated lung injury. Critical reviews examine the evidence for radical species in ethanol-induced liver injury and in muscular dystrophy. The wealth of new information presented makes this book valuable for teaching and an important reference volume for researchers exploring problems in human disease.

Author : TARR,M.,SAMSON,F.
Publisher : Springer Science & Business Media
Page : 306 pages
File Size : 41,9 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781461598404

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Oxygen Free Radicals in Tissue Damage by TARR,M.,SAMSON,F. Pdf

Oxygen free radicals and other reactive oxygen species are being postulated as causal agents in an increasing number of pathological conditions. Indeed, some investigators are suggesting that highly destructive reactive oxygen species are the final common path lead ing to tissue damage following a wide variety of insults including trauma, hypoxia, ischemia, hyperoxia, radiation, some toxins, and even strenuous athletic pursuits. But, as Robert Floyd points out, "Proof of the importance of oxygen free radicals and the oxidative damage they initiate depend on unequivocal evidence for the pres ence of free radicals and a clear association of their formation with the induction of the dysfunction of pathological conditions. " Since such proof does not come easily, there have been and will continue to be many controversies regarding the role played by reactive oxygen species in tissue damage. There have been many recent reviews of the chemistry and pos sible role of reactive oxygen species in many types of organ dys functions, tissue damage, degenerative diseases, and aging. This book is not such a review. Rather it presents for a diverse audience of physical-organic chemists, biochemists, medical researchers, and other investigators of pathophysiology, discussions of a variety of is sues important for understanding reactive oxygen species and their role in tissue damage.

Author : Manfred Lamprecht
Publisher : CRC Press
Page : 304 pages
File Size : 48,9 Mb
Release : 2014-09-17
Category : Medical
ISBN : 9781466567573

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Antioxidants in Sport Nutrition by Manfred Lamprecht Pdf

The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.

Author : Val Vallyathan
Publisher : Unknown
Page : 550 pages
File Size : 52,7 Mb
Release : 2004-04
Category : Electronic
ISBN : 0824754468

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Oxygen/Nitrogen Radicals by Val Vallyathan Pdf

Author : Loutfy H. Madkour
Publisher : Academic Press
Page : 782 pages
File Size : 49,8 Mb
Release : 2020-06-27
Category : Medical
ISBN : 9780128224960

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Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms by Loutfy H. Madkour Pdf

Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS?mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals?induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and oxidative damage mechanisms. It also examines the nanotoxicity, cytotoxicity and genotoxicity mechanisms of nanomaterials and the effects of nanoparticle interactions. Antioxidant defense therapy and strategies for treatment round out the book, making it an ideal resource for researchers and professional scientists in toxicology, environmental chemistry, environmental science, nanomaterials and the pharmaceutical sciences. Covers the ecotoxicology of environmental heavy metal ions and the interactions between specific heavy metals?induced cell responses and oxidative stress Provides a better understanding of the mechanism of nanomaterial-induced toxicity as a first defense for hazard prevention Covers recent advances in new nanomedication technologies for the effects of NPs on oxidative stress, ROS and ER stress Discusses the effects of interactions between antioxidant defense therapy, ROS and strategies for treatment

Author : R. Gilberto González,Joshua A. Hirsch,Michael H. Lev,Pamela W. Schaefer,Lee H. Schwamm
Publisher : Springer Science & Business Media
Page : 299 pages
File Size : 41,6 Mb
Release : 2010-10-05
Category : Medical
ISBN : 9783642127519

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Acute Ischemic Stroke by R. Gilberto González,Joshua A. Hirsch,Michael H. Lev,Pamela W. Schaefer,Lee H. Schwamm Pdf

This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.

Author : Ismail Laher
Publisher : Springer
Page : 0 pages
File Size : 53,7 Mb
Release : 2014-06-16
Category : Medical
ISBN : 3642300170

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Systems Biology of Free Radicals and Antioxidants by Ismail Laher Pdf

The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings.

Author : POLI
Publisher : Birkhäuser
Page : 540 pages
File Size : 46,7 Mb
Release : 2013-03-11
Category : Science
ISBN : 9783034891165

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Free Radicals: from Basic Science to Medicine by POLI Pdf

Free radical-mediated reactions have been well known in chemistry and physical chemistry for many years. Applying this knowledge to living organisms, biochemists have shown that reactive free radicals are formed at many intracellular sites during normal metabolism, and they have started to suggest possible roles in various pathological processes and conditions, for example in radiation damage, in the metabolism of xenobiotics, in carcinogenesis and in metabolic disorders. At present, a large and relevant mass of experimental evidence supports the view that reactive free radicals are involved in the pathogenesis of several diseases and syndromes. This literature has captured the attention and interest of people involved in the biomedical field. Exciting developments in radical research are probable in the near future, establishing a greater interaction between basic science research and medicine. While the task of defining the involvement of free radicals in human pathology is difficult, it is nonetheless extremely important that such interaction be fulfilled as soon as possible. These were the considerations motivating us during the organization of the VI Biennial Meeting of the International Society for Free Radical Research held in Torino, Italy, in June 1992, and also during the preparation of this book. Experts in the various aspects of free radical research were invited to participate in the Torino Meeting and to contribute chapters for this volume.