Oxygen Nitrogen Radicals And Cellular Injury

Author : Val Vallyathan,Vince Castranova,Xianglin Shi
Publisher : Springer Science & Business Media
Page : 393 pages
File Size : 48,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461510871

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Oxygen/Nitrogen Radicals: Cell Injury and Disease by Val Vallyathan,Vince Castranova,Xianglin Shi Pdf

A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.

Author : Kenneth B. Adler,Robert D. Devlin,Val Vallyathan
Publisher : DIANE Publishing
Page : 142 pages
File Size : 54,5 Mb
Release : 2000-03
Category : Electronic
ISBN : 9780788185380

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Oxygen/Nitrogen Radicals and Cellular Injury by Kenneth B. Adler,Robert D. Devlin,Val Vallyathan Pdf

Papers: characterization of inducible nitric oxide synthase expression in human airway epithelium; nitric oxide and its congeners in mitochondria; role of nitric oxide in inflammation and tissue injury during endotoxemia and hemorrhagic shock; nitric oxide and peroxynitrite production in ocular inflammation; 5 papers on pulmonary/pollutant effects; 6 papers on oxidants and signal transduction, including impact of oxidative stress on signal transduction control by phosphotyrosine phosphatases; the nature of antioxidant defense mechanisms; lipid peroxidation products and antioxidants in human disease; and lung injury and oxidoreductases.

Author : Kenneth B. Adler,Robert D. Devlin,Val Vallyathan
Publisher : Unknown
Page : 160 pages
File Size : 44,9 Mb
Release : 1998
Category : Antioxidants
ISBN : IND:30000143536013

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Oxygen/nitrogen Radicals and Cellular Injury by Kenneth B. Adler,Robert D. Devlin,Val Vallyathan Pdf

Author : Anonim
Publisher : Unknown
Page : 244 pages
File Size : 54,7 Mb
Release : 1994
Category : Active oxygen
ISBN : IND:30000143535577

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Oxygen Radicals and Lung Injury by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 409 pages
File Size : 45,7 Mb
Release : 2002
Category : Electronic
ISBN : OCLC:51022009

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Oxygen/nitrogen Radicals by Anonim Pdf

Author : Val Vallyathan,Vincent Castranova,Xianglin Shi
Publisher : CRC Press
Page : 550 pages
File Size : 44,9 Mb
Release : 2004-04-14
Category : Medical
ISBN : 0824748743

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Oxygen/Nitrogen Radicals by Val Vallyathan,Vincent Castranova,Xianglin Shi Pdf

The first state-of-the-art book dealing specifically with lung injury induced by oxygen and nitrogen radicals, this detailed treatise discusses molecular, cellular, and mechanistic events leading to pathophysiological outcomes; the role of oxidant species in the induction of these events; and potential therapeutic avenues targeting such molecular pathways. Important issues regarding oxidative stress involvement in the initiation and progression of pulmonary diseases-including diseases caused by occupational and environmental inhalation of toxicants-are discussed in the context of amelioration by antioxidants.

Author : Kenneth B. Adler
Publisher : Unknown
Page : 142 pages
File Size : 49,7 Mb
Release : 1998
Category : Electronic
ISBN : OCLC:214956039

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Oxygen Nitrogen Radicals and Cellular Injury by Kenneth B. Adler Pdf

Author : Mary Treinen Moslen,Charles V. Smith
Publisher : CRC Press
Page : 238 pages
File Size : 49,5 Mb
Release : 1992-02-21
Category : Science
ISBN : 0849351618

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Free Radical Mechanisms of Tissue Injury by Mary Treinen Moslen,Charles V. Smith Pdf

This timely volume describes the contributions of free radicals and reactive oxygen species to disease processes in a variety of tissues. Topics include the roles of lipid peroxide-modified lipoproteins in atherosclerosis, peroxidation products in retinopathy, reactive oxygen species and neutrophils in mycardial ischemia-reflow injury, iron and reactive oxygen species in hemoglobin-mediated CNS damage and in asbestos-mediated lung injury. Critical reviews examine the evidence for radical species in ethanol-induced liver injury and in muscular dystrophy. The wealth of new information presented makes this book valuable for teaching and an important reference volume for researchers exploring problems in human disease.

Author : TARR,M.,SAMSON,F.
Publisher : Springer Science & Business Media
Page : 306 pages
File Size : 47,7 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781461598404

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Oxygen Free Radicals in Tissue Damage by TARR,M.,SAMSON,F. Pdf

Oxygen free radicals and other reactive oxygen species are being postulated as causal agents in an increasing number of pathological conditions. Indeed, some investigators are suggesting that highly destructive reactive oxygen species are the final common path lead ing to tissue damage following a wide variety of insults including trauma, hypoxia, ischemia, hyperoxia, radiation, some toxins, and even strenuous athletic pursuits. But, as Robert Floyd points out, "Proof of the importance of oxygen free radicals and the oxidative damage they initiate depend on unequivocal evidence for the pres ence of free radicals and a clear association of their formation with the induction of the dysfunction of pathological conditions. " Since such proof does not come easily, there have been and will continue to be many controversies regarding the role played by reactive oxygen species in tissue damage. There have been many recent reviews of the chemistry and pos sible role of reactive oxygen species in many types of organ dys functions, tissue damage, degenerative diseases, and aging. This book is not such a review. Rather it presents for a diverse audience of physical-organic chemists, biochemists, medical researchers, and other investigators of pathophysiology, discussions of a variety of is sues important for understanding reactive oxygen species and their role in tissue damage.

Author : Manfred Lamprecht
Publisher : CRC Press
Page : 304 pages
File Size : 50,6 Mb
Release : 2014-09-17
Category : Medical
ISBN : 9781466567573

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Antioxidants in Sport Nutrition by Manfred Lamprecht Pdf

The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.

Author : Val Vallyathan
Publisher : Unknown
Page : 550 pages
File Size : 49,7 Mb
Release : 2004-04
Category : Electronic
ISBN : 0824754468

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Oxygen/Nitrogen Radicals by Val Vallyathan Pdf

Author : Loutfy H. Madkour
Publisher : Academic Press
Page : 782 pages
File Size : 50,5 Mb
Release : 2020-06-27
Category : Medical
ISBN : 9780128224960

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Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms by Loutfy H. Madkour Pdf

Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS?mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals?induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and oxidative damage mechanisms. It also examines the nanotoxicity, cytotoxicity and genotoxicity mechanisms of nanomaterials and the effects of nanoparticle interactions. Antioxidant defense therapy and strategies for treatment round out the book, making it an ideal resource for researchers and professional scientists in toxicology, environmental chemistry, environmental science, nanomaterials and the pharmaceutical sciences. Covers the ecotoxicology of environmental heavy metal ions and the interactions between specific heavy metals?induced cell responses and oxidative stress Provides a better understanding of the mechanism of nanomaterial-induced toxicity as a first defense for hazard prevention Covers recent advances in new nanomedication technologies for the effects of NPs on oxidative stress, ROS and ER stress Discusses the effects of interactions between antioxidant defense therapy, ROS and strategies for treatment

Author : Mirza Hasanuzzaman,Vasileios Fotopoulos,Kamrun Nahar,Masayuki Fujita
Publisher : John Wiley & Sons
Page : 1024 pages
File Size : 54,5 Mb
Release : 2019-07-02
Category : Science
ISBN : 9781119468660

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Reactive Oxygen, Nitrogen and Sulfur Species in Plants by Mirza Hasanuzzaman,Vasileios Fotopoulos,Kamrun Nahar,Masayuki Fujita Pdf

Presents a multidisciplinary analysis of the integration among reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS). Since plants are the main source of our food, the improvement of their productivity is the most important task for plant biologists. In this book, leading experts accumulate the recent development in the research on oxidative stress and approaches to enhance antioxidant defense system in crop plants. They discuss both the plant responses to oxidative stress and mechanisms of abiotic stress tolerance, and cover all of the recent approaches towards understanding oxidative stress in plants, providing comprehensive information about the topics. It also discusses how reactive nitrogen species and reactive sulfur species regulate plant physiology and plant tolerance to environmental stresses. Reactive Oxygen, Nitrogen and Sulfur Species in Plants: Production, Metabolism, Signaling and Defense Mechanisms covers everything readers need to know in four comprehensive sections. It starts by looking at reactive oxygen species metabolism and antioxidant defense. Next, it covers reactive nitrogen species metabolism and signaling before going on to reactive sulfur species metabolism and signaling. The book finishes with a section that looks at crosstalk among reactive oxygen, nitrogen, and sulfur species based on current research done by experts. Presents the newest method for understanding oxidative stress in plants. Covers both the plant responses to oxidative stress and mechanisms of abiotic stress tolerance Details the integration among reactive oxygen species (ROS), reactive nitrogen species (RNS) and reactive sulfur species (RSS) Written by 140 experts in the field of plant stress physiology, crop improvement, and genetic engineering Providing a comprehensive collection of up-to-date knowledge spanning from biosynthesis and metabolism to signaling pathways implicated in the involvement of RONSS to plant defense mechanisms, Reactive Oxygen, Nitrogen and Sulfur Species in Plants: Production, Metabolism, Signaling and Defense Mechanisms is an excellent book for plant breeders, molecular biologists, and plant physiologists, as well as a guide for students in the field of Plant Science.

Author : Ismail Laher
Publisher : Springer
Page : 0 pages
File Size : 53,9 Mb
Release : 2014-06-16
Category : Medical
ISBN : 3642300170

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Systems Biology of Free Radicals and Antioxidants by Ismail Laher Pdf

The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings.

Author : Sivakumar Joghi Thatha Gowder
Publisher : BoD – Books on Demand
Page : 330 pages
File Size : 53,8 Mb
Release : 2015-11-11
Category : Science
ISBN : 9789535122005

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Basic Principles and Clinical Significance of Oxidative Stress by Sivakumar Joghi Thatha Gowder Pdf

It is a natural phenomenon for all living organisms in the world to undergo different kinds of stress during their life span. Stress has become a common problem for human beings in this materialistic world. In this period, a publication of any material on stress will be helpful for the human society. The book Basic Principles and Clinical Significance of Oxidative Stress targets all aspects of oxidative stress, including principles, mechanisms, and clinical significance. This book covers four sections: Free Radicals and Oxidative Stress, Natural Compounds as Antioxidants, Antioxidants - Health and Disease, and Oxidative Stress and Therapy. Each of these sections is interwoven with the theoretical aspects and experimental techniques of basic and clinical sciences. This book will be a significant source to scientists, physicians, healthcare professionals, and students who are interested in exploring the effect of stress on human life.