Polyphenols In Human Health And Disease

Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Page : 470 pages
File Size : 44,5 Mb
Release : 2018-08-06
Category : Medical
ISBN : 9780128130070

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Polyphenols in Human Health and Disease by Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi Pdf

Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities. Expands coverage on green tea, cocoa, wine, cumin and herbs Outlines their chemical properties, bioavailability and metabolomics Provides a self-teaching guide to learn the mechanisms of action and health benefits of polyphenols

Author : Ronald Ross Watson,Victor R.. Preedy,Sherma Zibadi
Publisher : Unknown
Page : 545 pages
File Size : 46,6 Mb
Release : 2014
Category : Polyphenols
ISBN : 0123984726

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Polyphenols in Human Health and Disease by Ronald Ross Watson,Victor R.. Preedy,Sherma Zibadi Pdf

"Polyphenols are a unique group of phytochemicals that are present in all fruits, vegetables, and other plant products. They are classified according to their chemical structure, which contains multiple linked phenol groups and they have powerful antioxidant properties. There is a great variety of biological systems that can be positively modified by polyphenols in foods and dietary supplements. As the major focus on polyphenols is their biomodification of human physiology the functional mechanisms of action, positive or negative are critical. These can range from being antioxidants that concentrate in specific locations or cell types as protection to bioregulators of enzymes and DNA. Understanding the mechanisms of action, expecially protection from oxidative damage, is essential for researchers and physicians conducting clinical studies on the application of polyphenols to a wide variety of diseases and physiological dysfunctions."--

Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Page : 484 pages
File Size : 42,6 Mb
Release : 2018-08-06
Category : Medical
ISBN : 9780128130094

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Polyphenols in Human Health and Disease by Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi Pdf

Polyphenols in Prevention and Treatment of Human Disease, Second Edition authoritatively covers evidence of the powerful health benefits of polyphenols, touching on cardiovascular disease, cancer, obesity, diabetes and osteoporosis. This collection represents the contributions of an international group of experts in polyphenol research who share their expertise in endocrinology, public health, cardiology, pharmacology, agriculture and veterinary science. Researchers from diverse backgrounds will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted insights into the mechanisms of disease. This reference fills a void in research where nutritionists and alternative therapies may be applicable. Describes polyphenol modulation of blood flow and oxygenation as a potential mechanism of protection against vascular atherosclerosis Describes how polyphenols and antioxidants frequently change immune defenses and actions Focuses on the most important areas of research and provides insights into their relationships and translational opportunities

Author : Dr. Latika Yadav,Dr. Sadhna Singh,Neelesh Kumar Maurya
Publisher : DARSHAN PUBLISHERS
Page : 349 pages
File Size : 54,7 Mb
Release : 2022-06-06
Category : Antiques & Collectibles
ISBN : 9788195460274

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POLYPHENOLS IN HEALTH AND DISEASES by Dr. Latika Yadav,Dr. Sadhna Singh,Neelesh Kumar Maurya Pdf

Author : Anna Tresserra-Rimbau
Publisher : MDPI
Page : 248 pages
File Size : 43,6 Mb
Release : 2020-12-23
Category : Medical
ISBN : 9783039437931

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Dietary Polyphenols and Human Health by Anna Tresserra-Rimbau Pdf

Polyphenols are a heterogeneous group of bioactive compounds mainly found in plant-based foods. Numerous clinical and epidemiological studies have led to the result that polyphenol intake may protect against chronic diseases such as cardiovascular and neurodegenerative diseases, cancer, or type 2 diabetes, to name some. Polyphenol intake estimation can be obtained through food frequency questionnaires and nutritional biomarkers, both having their own advantages and disadvantages. Although the association between these bioactive compounds and health seems irrefutable, many questions remain still unanswered. For instance, more studies are needed to identify possible interactions and effect-modulating variables, such as smoking habit, body mass index, sex, alcohol, hormones, other foods, etc. Moreover, intestinal microbiota seems to play an important role in the metabolism of polyphenols, but it is still unclear how.

Author : Ronald R. Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Unknown
Page : 128 pages
File Size : 51,8 Mb
Release : 2014
Category : Electronic
ISBN : 0123984726

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Polyphenols in Human Health and Disease by Ronald R. Watson,Victor R. Preedy,Sherma Zibadi Pdf

Author : Institute of Medicine,Food and Nutrition Board,Committee on Nutrition, Trauma, and the Brain
Publisher : National Academies Press
Page : 444 pages
File Size : 47,6 Mb
Release : 2011-07-01
Category : Medical
ISBN : 9780309210089

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Nutrition and Traumatic Brain Injury by Institute of Medicine,Food and Nutrition Board,Committee on Nutrition, Trauma, and the Brain Pdf

Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.

Author : Anna Tresserra-Rimbau
Publisher : Unknown
Page : 248 pages
File Size : 43,8 Mb
Release : 2020
Category : Electronic
ISBN : 3039437941

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Dietary Polyphenols and Human Health by Anna Tresserra-Rimbau Pdf

Polyphenols are a heterogeneous group of bioactive compounds mainly found in plant-based foods. Numerous clinical and epidemiological studies have led to the result that polyphenol intake may protect against chronic diseases such as cardiovascular and neurodegenerative diseases, cancer, or type 2 diabetes, to name some. Polyphenol intake estimation can be obtained through food frequency questionnaires and nutritional biomarkers, both having their own advantages and disadvantages. Although the association between these bioactive compounds and health seems irrefutable, many questions remain still unanswered. For instance, more studies are needed to identify possible interactions and effect-modulating variables, such as smoking habit, body mass index, sex, alcohol, hormones, other foods, etc. Moreover, intestinal microbiota seems to play an important role in the metabolism of polyphenols, but it is still unclear how.

Author : Kaïs Hussain Al-Gubory,Ismail Laher
Publisher : Springer
Page : 553 pages
File Size : 47,7 Mb
Release : 2018-03-10
Category : Medical
ISBN : 9783319676258

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Nutritional Antioxidant Therapies: Treatments and Perspectives by Kaïs Hussain Al-Gubory,Ismail Laher Pdf

This book offers a collection of expert reviews on the use of plant-based antioxidant therapies in disease prevention and treatment. Topics discussed include the uses of plant and nutritional antioxidants in the contexts of reproductive health and prenatal development, healthcare and aging, noncommunicable chronic diseases, and environmental pollution. The text is complemented by a wealth of color figures and summary tables.

Author : Francisco A . Tomás-Barberán,Antonio González-Sarrías,Rocío García-Villalba
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 51,7 Mb
Release : 2020-12-15
Category : Technology & Engineering
ISBN : 9781119563723

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Dietary Polyphenols by Francisco A . Tomás-Barberán,Antonio González-Sarrías,Rocío García-Villalba Pdf

Presents recent research on metabolism and the health effects of polyphenols Consumer interest in the health benefits of many phenolic compounds found in plant foods and derivatives has grown considerably in recent years, giving rise to an increased demand for functional foods. Although preclinical and observational studies have promoted the protective properties of polyphenols for a range of chronic diseases, evidence has shown that most dietary polyphenols have little bioavailability. Once ingested, most of them are metabolized by either the intestinal enzymes or by the gut microbiota and then undergo extensive phase-II metabolism reaching significant concentrations of conjugated metabolites. They remain in the systemic circulation and target systemic tissues where trigger biological effects. The polyphenol-derived metabolites produced in humans are dependent upon the composition of the gut microbiota and the subject genetics. Thus all the metabolites do not show the same biological activity in different individuals. To fully understand the health effects of polyphenols, further clinical investigations are required. Dietary Polyphenols describes the latest findings on the polyphenol metabolism and reviews the current evidence on their health effects and that of their bioavailable metabolites. Emphasizing the importance of interindividual variability and the critical role of gut microbiota, this authoritative volume features contributions from recognized experts in the field, exploring specific families of extractable and non-extractable phenolic compounds that exhibit potential health effects. Topics include structural diversity of polyphenols and distribution in foods, bioavailability and bioaccessibility of phenolics, metabolism, and gastrointestinal absorption of various metabolites and their health effects. This comprehensive volume: Discusses the bioavailability, bioaccessibility, pharmacokinetics studies, and microbial metabolism of different groups of phenolic compounds Examines the interaction between polyphenols and gut microbiota Describes analytical methods for identifying and quantifying polyphenols in foods and biological samples Reviews recent epidemiological and clinical intervention studies showing protective effects of polyphenols Dietary Polyphenols: Metabolism and Health Effects is an important resource for scientists working in the area of dietary polyphenols and health effects, microbiota, and their interaction with other nutritional compounds, and for health professionals, nutritionists, dieticians, and clinical researchers with interest in the role of polyphenols in the prevention and treatment of chronic diseases.

Author : Ronald Ross Watson,Victor Preedy,Sherma Zibadi
Publisher : Academic Press
Page : 0 pages
File Size : 46,6 Mb
Release : 2018-08-05
Category : Medical
ISBN : 0128130083

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Polyphenols: Prevention and Treatment of Human Disease by Ronald Ross Watson,Victor Preedy,Sherma Zibadi Pdf

Polyphenols in Prevention and Treatment of Human Disease, Second Edition authoritatively covers evidence of the powerful health benefits of polyphenols, touching on cardiovascular disease, cancer, obesity, diabetes and osteoporosis. This collection represents the contributions of an international group of experts in polyphenol research who share their expertise in endocrinology, public health, cardiology, pharmacology, agriculture and veterinary science. Researchers from diverse backgrounds will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted insights into the mechanisms of disease. This reference fills a void in research where nutritionists and alternative therapies may be applicable.

Author : Mithun Rudrapal
Publisher : CRC Press
Page : 0 pages
File Size : 55,6 Mb
Release : 2022-12
Category : Medical
ISBN : 1003251536

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Dietary Polyphenols in Human Diseases by Mithun Rudrapal Pdf

"Diets rich in plant polyphenols or dietary polyphenols are the subject of increasing scientific interest because of having diverse range of health benefits and medicinal uses. The book titled "Dietary Polyphenols in Human Diseases: Advances and Challenges in Drug Discovery" is indented to fill the gap that exist in the current knowledge by presenting the latest information in the area/ topic of research interest. This book focuses on the current understanding of the beneficial effects of diets rich in polyphenols and/or polyphenolic compounds derived from dietary sources (plant-based foods) on human health and their possible preventive role in the management of chronic human diseases. In addition, biochemical mechanisms involved in the antioxidative effect of dietary polyphenols along with their bioavailability, pharmacokinetic, and toxicological considerations are also discussed herein. Key features: presents health benefits and medicinal importance of dietary polyphenols having antioxidative effects and their possible preventive role against oxidative stress (OS)-induced chronic human diseases, summarizes latest understanding on the biochemical mechanism(s) involved in the antioxidative action of dietary polyphenols along with their bioavailability, pharmacokinetic, and toxicological considerations, and highlights novel approaches of drug discovery from dietary polyphenols through computational screening of bioactive phytochemical components.With contributions by a global team of experts (academicians, scientists, and researchers), this book is intended to be a useful resource to a wider audience, particularly those working in the area of drug discovery and development research, such as discovery scientists, pharmaceutical scientists (R&D), formulation scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, clinicians, researchers, students, teachers, and many others"--

Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Page : 1488 pages
File Size : 50,5 Mb
Release : 2013-10-26
Category : Science
ISBN : 9780123984678

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Polyphenols in Human Health and Disease by Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi Pdf

Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more. Explores neuronal protection by polyphenol metabolites and their application to medical care Defines modulation of enzyme actions to help researchers see and study polyphenols’ mechanisms of action, leading to clinical applications Includes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases

Author : Asim K. Duttaroy
Publisher : Academic Press
Page : 475 pages
File Size : 41,6 Mb
Release : 2021-07-08
Category : Health & Fitness
ISBN : 9780128221945

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Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease by Asim K. Duttaroy Pdf

Evidence-Based Nutrition and Clinical Evidence of Bioactive Foods in Human Health and Disease explores a wide range of studies from clinical investigations to mechanistic research, covering the actions of bioactives on specific tissues and cells in intestinal, neurological, immunological and cardiovascular health and disease, including cancers. The book also focuses on metabolism, mechanisms of actions, tissue-specific effects, and the structure–function relationships between clinical trial, ex vivo and in vitro data. Written for nutrition researchers, clinical researchers, dieticians, and others working in and studying health-related fields, this book highlights the concepts surrounding the preventive and therapeutic impacts of bioactive foods. Presents information on the prevention of disease using bioactive compounds Consolidates the research outcome from a variety of sources on specific bioactive foods Contains coverage of bioactive lipids and lipid mediators, bioactive phytochemicals, probiotics, bioactive proteins, peptides, polysaccharides, fibers and sphingolipids

Author : AnnMarie Kocher,Joseph Loscalzo
Publisher : Springer Science & Business Media
Page : 306 pages
File Size : 52,7 Mb
Release : 2011-04-15
Category : Medical
ISBN : 9781607616160

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Nitrite and Nitrate in Human Health and Disease by AnnMarie Kocher,Joseph Loscalzo Pdf

Nitrite and Nitrate in Human Health and Disease delivers a comprehensive review of nitrite and nitrate biology, from basic biochemistry to the complex physiology and metabolism of these two naturally occurring molecules in the human body. Well-organized and well referenced chapters cover the rich history of nitrite and nitrate, sources of exposure, and the physiological effects when consumed through foods containing nitrite and nitrate. The chapters are written by leading experts, all of whom share their research and perspectives in order to help define the context for benefits vs. any potential risks associated with nitrite and nitrate use, either through dietary ingestion or therapeutic dosing. This diverse collection of authors includes vascular biologists, physiologists, physicians, epidemiologists, cancer biologists, registered dieticians, chemists, and public health experts from five countries in both academia and government. Nitrite and Nitrate in Human Health and Disease provides a balanced view of nitric oxide biochemistry, and nitrite and nitrate biochemistry in physiology and in the food sciences.