Dietary Polyphenols In Human Diseases

Author : Mithun Rudrapal
Publisher : CRC Press
Page : 415 pages
File Size : 42,6 Mb
Release : 2022-12-29
Category : Medical
ISBN : 9781000803235

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Dietary Polyphenols in Human Diseases by Mithun Rudrapal Pdf

Diets rich in plant polyphenols or dietary polyphenols are the subject of increasing scientific interest because of their diverse range of health benefits and medicinal uses. This book, Dietary Polyphenols in Human Diseases: Advances and Challenges in Drug Discovery, fills the gap that exists in the current knowledge by presenting the latest information in the area of polyphenol-based drug discovery research. The book focuses on the current understanding of the beneficial effects on human health of diets rich in polyphenols and/or polyphenolic compounds derived from dietary sources (plant-based foods) and their possible preventive role in the management of chronic human diseases. In addition, biochemical mechanisms involved in the antioxidative effect of dietary polyphenols along with their bioavailability, pharmacokinetic, and toxicological considerations are also discussed herein. Key Features Presents health benefits and medicinal importance of dietary polyphenols having antioxidative effects and their possible preventive role against oxidative stress (OS)-induced chronic human diseases. Summarizes the latest understanding of the biochemical mechanism(s) involved in the antioxidative action of dietary polyphenols along with their bioavailability, pharmacokinetic, and toxicological considerations. Highlights novel approaches of drug discovery from dietary polyphenols through computational screening of bioactive phytochemical components. With contributions by a global team of experts (academics, scientists, and researchers), this book is intended to be a useful resource for a wider audience, particularly those working in the area of drug discovery and development research, such as discovery scientists, pharmaceutical scientists (R&D), formulation scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, clinicians, researchers, students, teachers, and many others.

Author : Kaïs Hussain Al-Gubory,Ismail Laher
Publisher : Springer
Page : 553 pages
File Size : 45,6 Mb
Release : 2018-03-10
Category : Medical
ISBN : 9783319676258

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Nutritional Antioxidant Therapies: Treatments and Perspectives by Kaïs Hussain Al-Gubory,Ismail Laher Pdf

This book offers a collection of expert reviews on the use of plant-based antioxidant therapies in disease prevention and treatment. Topics discussed include the uses of plant and nutritional antioxidants in the contexts of reproductive health and prenatal development, healthcare and aging, noncommunicable chronic diseases, and environmental pollution. The text is complemented by a wealth of color figures and summary tables.

Author : Anna Tresserra-Rimbau
Publisher : MDPI
Page : 248 pages
File Size : 48,8 Mb
Release : 2020-12-23
Category : Medical
ISBN : 9783039437931

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Dietary Polyphenols and Human Health by Anna Tresserra-Rimbau Pdf

Polyphenols are a heterogeneous group of bioactive compounds mainly found in plant-based foods. Numerous clinical and epidemiological studies have led to the result that polyphenol intake may protect against chronic diseases such as cardiovascular and neurodegenerative diseases, cancer, or type 2 diabetes, to name some. Polyphenol intake estimation can be obtained through food frequency questionnaires and nutritional biomarkers, both having their own advantages and disadvantages. Although the association between these bioactive compounds and health seems irrefutable, many questions remain still unanswered. For instance, more studies are needed to identify possible interactions and effect-modulating variables, such as smoking habit, body mass index, sex, alcohol, hormones, other foods, etc. Moreover, intestinal microbiota seems to play an important role in the metabolism of polyphenols, but it is still unclear how.

Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Page : 484 pages
File Size : 46,7 Mb
Release : 2018-08-06
Category : Medical
ISBN : 9780128130094

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Polyphenols in Human Health and Disease by Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi Pdf

Polyphenols in Prevention and Treatment of Human Disease, Second Edition authoritatively covers evidence of the powerful health benefits of polyphenols, touching on cardiovascular disease, cancer, obesity, diabetes and osteoporosis. This collection represents the contributions of an international group of experts in polyphenol research who share their expertise in endocrinology, public health, cardiology, pharmacology, agriculture and veterinary science. Researchers from diverse backgrounds will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted insights into the mechanisms of disease. This reference fills a void in research where nutritionists and alternative therapies may be applicable. Describes polyphenol modulation of blood flow and oxygenation as a potential mechanism of protection against vascular atherosclerosis Describes how polyphenols and antioxidants frequently change immune defenses and actions Focuses on the most important areas of research and provides insights into their relationships and translational opportunities

Author : Francisco A . Tomás-Barberán,Antonio González-Sarrías,Rocío García-Villalba
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 46,6 Mb
Release : 2020-10-29
Category : Technology & Engineering
ISBN : 9781119563747

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Dietary Polyphenols by Francisco A . Tomás-Barberán,Antonio González-Sarrías,Rocío García-Villalba Pdf

Presents recent research on metabolism and the health effects of polyphenols Consumer interest in the health benefits of many phenolic compounds found in plant foods and derivatives has grown considerably in recent years, giving rise to an increased demand for functional foods. Although preclinical and observational studies have promoted the protective properties of polyphenols for a range of chronic diseases, evidence has shown that most dietary polyphenols have little bioavailability. Once ingested, most of them are metabolized by either the intestinal enzymes or by the gut microbiota and then undergo extensive phase-II metabolism reaching significant concentrations of conjugated metabolites. They remain in the systemic circulation and target systemic tissues where trigger biological effects. The polyphenol-derived metabolites produced in humans are dependent upon the composition of the gut microbiota and the subject genetics. Thus all the metabolites do not show the same biological activity in different individuals. To fully understand the health effects of polyphenols, further clinical investigations are required. Dietary Polyphenols describes the latest findings on the polyphenol metabolism and reviews the current evidence on their health effects and that of their bioavailable metabolites. Emphasizing the importance of interindividual variability and the critical role of gut microbiota, this authoritative volume features contributions from recognized experts in the field, exploring specific families of extractable and non-extractable phenolic compounds that exhibit potential health effects. Topics include structural diversity of polyphenols and distribution in foods, bioavailability and bioaccessibility of phenolics, metabolism, and gastrointestinal absorption of various metabolites and their health effects. This comprehensive volume: Discusses the bioavailability, bioaccessibility, pharmacokinetics studies, and microbial metabolism of different groups of phenolic compounds Examines the interaction between polyphenols and gut microbiota Describes analytical methods for identifying and quantifying polyphenols in foods and biological samples Reviews recent epidemiological and clinical intervention studies showing protective effects of polyphenols Dietary Polyphenols: Metabolism and Health Effects is an important resource for scientists working in the area of dietary polyphenols and health effects, microbiota, and their interaction with other nutritional compounds, and for health professionals, nutritionists, dieticians, and clinical researchers with interest in the role of polyphenols in the prevention and treatment of chronic diseases.

Author : Dr. Latika Yadav,Dr. Sadhna Singh,Neelesh Kumar Maurya
Publisher : DARSHAN PUBLISHERS
Page : 349 pages
File Size : 49,8 Mb
Release : 2022-06-06
Category : Antiques & Collectibles
ISBN : 9788195460274

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POLYPHENOLS IN HEALTH AND DISEASES by Dr. Latika Yadav,Dr. Sadhna Singh,Neelesh Kumar Maurya Pdf

Author : Anna Tresserra-Rimbau
Publisher : Unknown
Page : 248 pages
File Size : 50,5 Mb
Release : 2020
Category : Electronic
ISBN : 3039437941

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Dietary Polyphenols and Human Health by Anna Tresserra-Rimbau Pdf

Polyphenols are a heterogeneous group of bioactive compounds mainly found in plant-based foods. Numerous clinical and epidemiological studies have led to the result that polyphenol intake may protect against chronic diseases such as cardiovascular and neurodegenerative diseases, cancer, or type 2 diabetes, to name some. Polyphenol intake estimation can be obtained through food frequency questionnaires and nutritional biomarkers, both having their own advantages and disadvantages. Although the association between these bioactive compounds and health seems irrefutable, many questions remain still unanswered. For instance, more studies are needed to identify possible interactions and effect-modulating variables, such as smoking habit, body mass index, sex, alcohol, hormones, other foods, etc. Moreover, intestinal microbiota seems to play an important role in the metabolism of polyphenols, but it is still unclear how.

Author : Ronald Ross Watson,Victor R.. Preedy,Sherma Zibadi
Publisher : Unknown
Page : 545 pages
File Size : 44,6 Mb
Release : 2014
Category : Polyphenols
ISBN : 0123984726

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Polyphenols in Human Health and Disease by Ronald Ross Watson,Victor R.. Preedy,Sherma Zibadi Pdf

"Polyphenols are a unique group of phytochemicals that are present in all fruits, vegetables, and other plant products. They are classified according to their chemical structure, which contains multiple linked phenol groups and they have powerful antioxidant properties. There is a great variety of biological systems that can be positively modified by polyphenols in foods and dietary supplements. As the major focus on polyphenols is their biomodification of human physiology the functional mechanisms of action, positive or negative are critical. These can range from being antioxidants that concentrate in specific locations or cell types as protection to bioregulators of enzymes and DNA. Understanding the mechanisms of action, expecially protection from oxidative damage, is essential for researchers and physicians conducting clinical studies on the application of polyphenols to a wide variety of diseases and physiological dysfunctions."--

Author : Neville Vassallo
Publisher : Nova Publishers
Page : 414 pages
File Size : 43,9 Mb
Release : 2008
Category : Flavonoids
ISBN : 1604563494

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Polyphenols and Health by Neville Vassallo Pdf

This book touches upon the subject of diet and health interest to a wide audience. It is a very topical subject and one which is at the forefront of scientific research, not only in universities but also in industry. The exponential increase in the number of scientific reports is a strong indicator of the need for this book that provides an exciting, up-to-date guide to the mechanisms and themes that underlie the applications of polyphenols in health.

Author : Kai Wang,Guiju Sun,Michael Allan Conlon,Guan Yang,Wenkai Ren
Publisher : Frontiers Media SA
Page : 274 pages
File Size : 42,5 Mb
Release : 2021-11-29
Category : Medical
ISBN : 9782889717101

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Dietary Polyphenols for Improving Gut Health: Volume 1 by Kai Wang,Guiju Sun,Michael Allan Conlon,Guan Yang,Wenkai Ren Pdf

Author : Giuseppe Grosso
Publisher : MDPI
Page : 361 pages
File Size : 42,6 Mb
Release : 2018-08-27
Category : Electronic books
ISBN : 9783038971412

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Effects of Polyphenol-Rich Foods on Human Health by Giuseppe Grosso Pdf

This book is a printed edition of the Special Issue "Effects of Polyphenol-Rich Foods on Human Health" that was published in Nutrients

Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Page : 470 pages
File Size : 40,7 Mb
Release : 2018-08-06
Category : Medical
ISBN : 9780128130070

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Polyphenols in Human Health and Disease by Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi Pdf

Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities. Expands coverage on green tea, cocoa, wine, cumin and herbs Outlines their chemical properties, bioavailability and metabolomics Provides a self-teaching guide to learn the mechanisms of action and health benefits of polyphenols

Author : Dean T. Cobb
Publisher : Nova Publishers
Page : 0 pages
File Size : 51,8 Mb
Release : 2016-12
Category : Antioxidants
ISBN : 1536100420

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Polyphenols by Dean T. Cobb Pdf

Polyphenols are secondary metabolites of plants. Dietary phenolics are not only classified as human nutrients, but also play important roles in human health and are therefore called nutraceuticals. Both epidemiological studies and controlled human studies have shown that regular intakes of diets rich in phenolics are inversely related to some chronic diseases such as certain cancers and coronary heart diseases. Types and contents of phenolics in different food system vary greatly and foods of plant origin including fruits, vegetables, legumes and some beverages are good sources of bioactive phenolics. Beside the edible part of plant foods, some agricultural by-products usually contain higher levels of polyphenols, particularly, flavonoids than products themselves. This book describes the major classes of dietary phenolics, and their occurrence in the commercially important agricultural by-products including peanuts skin, grape pomace, apples pomace, citrus processing by-products, and cranberry pomace. It also discusses the role of polyphenols in the prevention of ultraviolet light induced inflammation and immunosuppression; yerba mate; the Mediterranean diet; industrial apple pomace; the role of polyphenols in human diseases; and the influence of extraction methods on the stability of polyphenols.

Author : Institute of Medicine,Food and Nutrition Board,Committee on Nutrition, Trauma, and the Brain
Publisher : National Academies Press
Page : 444 pages
File Size : 48,8 Mb
Release : 2011-07-01
Category : Medical
ISBN : 9780309210089

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Nutrition and Traumatic Brain Injury by Institute of Medicine,Food and Nutrition Board,Committee on Nutrition, Trauma, and the Brain Pdf

Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.

Author : Manfred Lamprecht
Publisher : CRC Press
Page : 304 pages
File Size : 43,9 Mb
Release : 2014-09-17
Category : Medical
ISBN : 9781466567573

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Antioxidants in Sport Nutrition by Manfred Lamprecht Pdf

The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.