Dietary Polyphenols And Human Health

Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Page : 1488 pages
File Size : 43,9 Mb
Release : 2013-10-26
Category : Science
ISBN : 9780123984678

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Polyphenols in Human Health and Disease by Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi Pdf

Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more. Explores neuronal protection by polyphenol metabolites and their application to medical care Defines modulation of enzyme actions to help researchers see and study polyphenols’ mechanisms of action, leading to clinical applications Includes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases

Author : Anna Tresserra-Rimbau
Publisher : MDPI
Page : 248 pages
File Size : 41,5 Mb
Release : 2020-12-23
Category : Medical
ISBN : 9783039437931

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Dietary Polyphenols and Human Health by Anna Tresserra-Rimbau Pdf

Polyphenols are a heterogeneous group of bioactive compounds mainly found in plant-based foods. Numerous clinical and epidemiological studies have led to the result that polyphenol intake may protect against chronic diseases such as cardiovascular and neurodegenerative diseases, cancer, or type 2 diabetes, to name some. Polyphenol intake estimation can be obtained through food frequency questionnaires and nutritional biomarkers, both having their own advantages and disadvantages. Although the association between these bioactive compounds and health seems irrefutable, many questions remain still unanswered. For instance, more studies are needed to identify possible interactions and effect-modulating variables, such as smoking habit, body mass index, sex, alcohol, hormones, other foods, etc. Moreover, intestinal microbiota seems to play an important role in the metabolism of polyphenols, but it is still unclear how.

Author : Francisco A . Tomás-Barberán,Antonio González-Sarrías,Rocío García-Villalba
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 53,5 Mb
Release : 2020-12-15
Category : Technology & Engineering
ISBN : 9781119563723

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Dietary Polyphenols by Francisco A . Tomás-Barberán,Antonio González-Sarrías,Rocío García-Villalba Pdf

Presents recent research on metabolism and the health effects of polyphenols Consumer interest in the health benefits of many phenolic compounds found in plant foods and derivatives has grown considerably in recent years, giving rise to an increased demand for functional foods. Although preclinical and observational studies have promoted the protective properties of polyphenols for a range of chronic diseases, evidence has shown that most dietary polyphenols have little bioavailability. Once ingested, most of them are metabolized by either the intestinal enzymes or by the gut microbiota and then undergo extensive phase-II metabolism reaching significant concentrations of conjugated metabolites. They remain in the systemic circulation and target systemic tissues where trigger biological effects. The polyphenol-derived metabolites produced in humans are dependent upon the composition of the gut microbiota and the subject genetics. Thus all the metabolites do not show the same biological activity in different individuals. To fully understand the health effects of polyphenols, further clinical investigations are required. Dietary Polyphenols describes the latest findings on the polyphenol metabolism and reviews the current evidence on their health effects and that of their bioavailable metabolites. Emphasizing the importance of interindividual variability and the critical role of gut microbiota, this authoritative volume features contributions from recognized experts in the field, exploring specific families of extractable and non-extractable phenolic compounds that exhibit potential health effects. Topics include structural diversity of polyphenols and distribution in foods, bioavailability and bioaccessibility of phenolics, metabolism, and gastrointestinal absorption of various metabolites and their health effects. This comprehensive volume: Discusses the bioavailability, bioaccessibility, pharmacokinetics studies, and microbial metabolism of different groups of phenolic compounds Examines the interaction between polyphenols and gut microbiota Describes analytical methods for identifying and quantifying polyphenols in foods and biological samples Reviews recent epidemiological and clinical intervention studies showing protective effects of polyphenols Dietary Polyphenols: Metabolism and Health Effects is an important resource for scientists working in the area of dietary polyphenols and health effects, microbiota, and their interaction with other nutritional compounds, and for health professionals, nutritionists, dieticians, and clinical researchers with interest in the role of polyphenols in the prevention and treatment of chronic diseases.

Author : Anna Tresserra-Rimbau
Publisher : Unknown
Page : 248 pages
File Size : 49,8 Mb
Release : 2020
Category : Electronic
ISBN : 3039437941

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Dietary Polyphenols and Human Health by Anna Tresserra-Rimbau Pdf

Polyphenols are a heterogeneous group of bioactive compounds mainly found in plant-based foods. Numerous clinical and epidemiological studies have led to the result that polyphenol intake may protect against chronic diseases such as cardiovascular and neurodegenerative diseases, cancer, or type 2 diabetes, to name some. Polyphenol intake estimation can be obtained through food frequency questionnaires and nutritional biomarkers, both having their own advantages and disadvantages. Although the association between these bioactive compounds and health seems irrefutable, many questions remain still unanswered. For instance, more studies are needed to identify possible interactions and effect-modulating variables, such as smoking habit, body mass index, sex, alcohol, hormones, other foods, etc. Moreover, intestinal microbiota seems to play an important role in the metabolism of polyphenols, but it is still unclear how.

Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Page : 470 pages
File Size : 52,6 Mb
Release : 2018-08-06
Category : Medical
ISBN : 9780128130070

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Polyphenols in Human Health and Disease by Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi Pdf

Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities. Expands coverage on green tea, cocoa, wine, cumin and herbs Outlines their chemical properties, bioavailability and metabolomics Provides a self-teaching guide to learn the mechanisms of action and health benefits of polyphenols

Author : Francisco A . Tomás-Barberán,Antonio González-Sarrías,Rocío García-Villalba
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 42,6 Mb
Release : 2020-10-29
Category : Technology & Engineering
ISBN : 9781119563747

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Dietary Polyphenols by Francisco A . Tomás-Barberán,Antonio González-Sarrías,Rocío García-Villalba Pdf

Presents recent research on metabolism and the health effects of polyphenols Consumer interest in the health benefits of many phenolic compounds found in plant foods and derivatives has grown considerably in recent years, giving rise to an increased demand for functional foods. Although preclinical and observational studies have promoted the protective properties of polyphenols for a range of chronic diseases, evidence has shown that most dietary polyphenols have little bioavailability. Once ingested, most of them are metabolized by either the intestinal enzymes or by the gut microbiota and then undergo extensive phase-II metabolism reaching significant concentrations of conjugated metabolites. They remain in the systemic circulation and target systemic tissues where trigger biological effects. The polyphenol-derived metabolites produced in humans are dependent upon the composition of the gut microbiota and the subject genetics. Thus all the metabolites do not show the same biological activity in different individuals. To fully understand the health effects of polyphenols, further clinical investigations are required. Dietary Polyphenols describes the latest findings on the polyphenol metabolism and reviews the current evidence on their health effects and that of their bioavailable metabolites. Emphasizing the importance of interindividual variability and the critical role of gut microbiota, this authoritative volume features contributions from recognized experts in the field, exploring specific families of extractable and non-extractable phenolic compounds that exhibit potential health effects. Topics include structural diversity of polyphenols and distribution in foods, bioavailability and bioaccessibility of phenolics, metabolism, and gastrointestinal absorption of various metabolites and their health effects. This comprehensive volume: Discusses the bioavailability, bioaccessibility, pharmacokinetics studies, and microbial metabolism of different groups of phenolic compounds Examines the interaction between polyphenols and gut microbiota Describes analytical methods for identifying and quantifying polyphenols in foods and biological samples Reviews recent epidemiological and clinical intervention studies showing protective effects of polyphenols Dietary Polyphenols: Metabolism and Health Effects is an important resource for scientists working in the area of dietary polyphenols and health effects, microbiota, and their interaction with other nutritional compounds, and for health professionals, nutritionists, dieticians, and clinical researchers with interest in the role of polyphenols in the prevention and treatment of chronic diseases.

Author : Kai Wang,Guiju Sun,Michael Allan Conlon,Guan Yang,Wenkai Ren
Publisher : Frontiers Media SA
Page : 274 pages
File Size : 43,5 Mb
Release : 2021-11-29
Category : Medical
ISBN : 9782889717101

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Dietary Polyphenols for Improving Gut Health: Volume 1 by Kai Wang,Guiju Sun,Michael Allan Conlon,Guan Yang,Wenkai Ren Pdf

Author : Kaïs Hussain Al-Gubory,Ismail Laher
Publisher : Springer
Page : 553 pages
File Size : 51,5 Mb
Release : 2018-03-10
Category : Medical
ISBN : 9783319676258

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Nutritional Antioxidant Therapies: Treatments and Perspectives by Kaïs Hussain Al-Gubory,Ismail Laher Pdf

This book offers a collection of expert reviews on the use of plant-based antioxidant therapies in disease prevention and treatment. Topics discussed include the uses of plant and nutritional antioxidants in the contexts of reproductive health and prenatal development, healthcare and aging, noncommunicable chronic diseases, and environmental pollution. The text is complemented by a wealth of color figures and summary tables.

Author : Neville Vassallo
Publisher : Nova Publishers
Page : 414 pages
File Size : 52,9 Mb
Release : 2008
Category : Flavonoids
ISBN : 1604563494

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Polyphenols and Health by Neville Vassallo Pdf

This book touches upon the subject of diet and health interest to a wide audience. It is a very topical subject and one which is at the forefront of scientific research, not only in universities but also in industry. The exponential increase in the number of scientific reports is a strong indicator of the need for this book that provides an exciting, up-to-date guide to the mechanisms and themes that underlie the applications of polyphenols in health.

Author : Mithun Rudrapal
Publisher : CRC Press
Page : 415 pages
File Size : 53,8 Mb
Release : 2022-12-29
Category : Medical
ISBN : 9781000803235

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Dietary Polyphenols in Human Diseases by Mithun Rudrapal Pdf

Diets rich in plant polyphenols or dietary polyphenols are the subject of increasing scientific interest because of their diverse range of health benefits and medicinal uses. This book, Dietary Polyphenols in Human Diseases: Advances and Challenges in Drug Discovery, fills the gap that exists in the current knowledge by presenting the latest information in the area of polyphenol-based drug discovery research. The book focuses on the current understanding of the beneficial effects on human health of diets rich in polyphenols and/or polyphenolic compounds derived from dietary sources (plant-based foods) and their possible preventive role in the management of chronic human diseases. In addition, biochemical mechanisms involved in the antioxidative effect of dietary polyphenols along with their bioavailability, pharmacokinetic, and toxicological considerations are also discussed herein. Key Features Presents health benefits and medicinal importance of dietary polyphenols having antioxidative effects and their possible preventive role against oxidative stress (OS)-induced chronic human diseases. Summarizes the latest understanding of the biochemical mechanism(s) involved in the antioxidative action of dietary polyphenols along with their bioavailability, pharmacokinetic, and toxicological considerations. Highlights novel approaches of drug discovery from dietary polyphenols through computational screening of bioactive phytochemical components. With contributions by a global team of experts (academics, scientists, and researchers), this book is intended to be a useful resource for a wider audience, particularly those working in the area of drug discovery and development research, such as discovery scientists, pharmaceutical scientists (R&D), formulation scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, clinicians, researchers, students, teachers, and many others.

Author : Dr. Latika Yadav,Dr. Sadhna Singh,Neelesh Kumar Maurya
Publisher : DARSHAN PUBLISHERS
Page : 349 pages
File Size : 42,9 Mb
Release : 2022-06-06
Category : Antiques & Collectibles
ISBN : 9788195460274

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POLYPHENOLS IN HEALTH AND DISEASES by Dr. Latika Yadav,Dr. Sadhna Singh,Neelesh Kumar Maurya Pdf

Author : Institute of Medicine,Food and Nutrition Board,Committee on Nutrition, Trauma, and the Brain
Publisher : National Academies Press
Page : 444 pages
File Size : 45,7 Mb
Release : 2011-07-01
Category : Medical
ISBN : 9780309210089

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Nutrition and Traumatic Brain Injury by Institute of Medicine,Food and Nutrition Board,Committee on Nutrition, Trauma, and the Brain Pdf

Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.

Author : Fulgencio Saura-Calixto,Jara Pérez-Jiménez
Publisher : Royal Society of Chemistry
Page : 398 pages
File Size : 42,8 Mb
Release : 2018-04-30
Category : Medical
ISBN : 9781788014472

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Non-extractable Polyphenols and Carotenoids by Fulgencio Saura-Calixto,Jara Pérez-Jiménez Pdf

Polyphenols and carotenoids are abundant in fruits, vegetables, herbs and spices, and beverages, such as tea, cocoa and wine providing health-related benefits and antioxidant properties. Focusing on non-extractable polyphenols and carotenoids that are present in the diet, this book will improve our knowledge of dietary intakes and physiological properties ensuring a better understanding of their potential health effects. With global appeal, this will be the first book dedicated to raising the profile of this important area. Summarising the current knowledge in the field, the book will direct further research for food chemists, scientists and nutritionists looking for new perspectives.

Author : Manfred Lamprecht
Publisher : CRC Press
Page : 304 pages
File Size : 55,5 Mb
Release : 2014-09-17
Category : Medical
ISBN : 9781466567573

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Antioxidants in Sport Nutrition by Manfred Lamprecht Pdf

The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.

Author : Elena González-Burgos,M Pilar G ́omez-Serranillos Cuadrado
Publisher : Mdpi AG
Page : 232 pages
File Size : 42,5 Mb
Release : 2022-01-21
Category : Medical
ISBN : 3036528989

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Effect of Phenolic Compounds on Human Health by Elena González-Burgos,M Pilar G ́omez-Serranillos Cuadrado Pdf

Phenolic compounds are non-essential dietary compounds that are found in many vegetables (i.e. onion, cabbage, broccoli and parsley), fruits (i.e. cherries, grapes, berries and pears), cereals and beverages (i.e. red wine, tea and chocolate). These heterogeneous compounds are produced as secondary metabolites. Structurally, these compounds are characterized by comprising an aromatic ring with one or more hydroxyl groups that can be classified into two groups: flavonoids and non-flavonoids. Phenolic compounds have received considerable attention for its health-promoting properties in many chronic disorders including diabetes, cardiovascular diseases, cancer and neurodegenerative diseases, among others. These health benefits are mainly attributed to its antioxidant properties. Phenolic compounds act as antioxidant by scavenging free radicals, metal chelation and endogenous antioxidant system upregulation (enzymatic antioxidants such as catalase, superoxide dismutase and glutathione peroxidase and non-enzymatic antioxidants such as glutathione). The consumption of exogenous medicinal plants and food rich in phenolic compounds represent a promising therapeutically to prevent many chronic diseases and improve health. This Special Issue entitled "Effect of Phenolic Compounds on Human Health" include research articles and review articles on phenolic compounds and its role in health (i.e. flavonoids and diabetes, polyphenols and liver diseases, polyphenols and obesity, polyphenols and cardiovascular diseases and polyphenols and neuroprotection).