Practical Hplc Methodology And Applications

Practical Hplc Methodology And Applications Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Practical Hplc Methodology And Applications book. This book definitely worth reading, it is an incredibly well-written.

Practical HPLC Methodology and Applications

Brian A. Bidlingmeyer
Practical HPLC Methodology and Applications Book PDF

Author : Brian A. Bidlingmeyer
Publisher : John Wiley & Sons
Page : 470 pages
File Size : 40,7 Mb
Release : 1993-05-06
Category : Science
ISBN : 0471572462

Get Book

Practical HPLC Methodology and Applications by Brian A. Bidlingmeyer Pdf

Of related interest. Trace and Ultratrace Analysis by HPLC Satinder Ahuja Written by a leading scientist in the field, this monograph provides the first definitive and technically up-to-date treatment of the theory, equipment, and applications of chemistry's most powerful reliable analytical technique. Coverage includes an encyclopedic compendium of common substances that require trace and ultratrace analysis, and features clear discussion of such important topics as considerations for HPLC equipment, sensitive detectors, sample preparation, method development, selectivity and computer-based optimizations, optimizing detectability, and much more. 1991 (0 471-51419-5) 432 pp. High Performance Liquid Chromatography in Biotechnology Edited by William S. Hancock Analytical chemists, biochemists, and chemical engineers will find this up-to-date guide to HPLC's recent developments essential for enhancing on-the-job technical expertise. Extensive coverage includes the broad applications of HPLC, ranging from major chromatographic techniques (including reversed phase, ion exchange, affinity and hydrophobic interaction chromatography) to specific separations such as those in monoclonal antibody and nucleic acid purification. Techniques for quality control programs and advanced technology are also discussed. 1990 (0 471-82584-0) 564 pp. Unified Separation Science J. Calvin Giddings This advanced text/monograph brings together for the first time the variety of techniques used for chemical separations by outlining their common underlying mechanisms. The mass transport phenomena underlying all separation processes are developed in a simple physical-mathematical form, facilitating analysis of alternative separation techniques and the factors integral to separation power. The first six chapters provide background material applicable to a wide range of separation methods, while the final five chapters illustrate specific techniques and methods. 1991 (0 471-52089-6) 320 pp.

Practical HPLC Method Development

Lloyd R. Snyder,Joseph J. Kirkland,Joseph L. Glajch
Practical HPLC Method Development Book PDF

Author : Lloyd R. Snyder,Joseph J. Kirkland,Joseph L. Glajch
Publisher : John Wiley & Sons
Page : 665 pages
File Size : 41,9 Mb
Release : 2012-12-03
Category : Science
ISBN : 9781118591512

Get Book

Practical HPLC Method Development by Lloyd R. Snyder,Joseph J. Kirkland,Joseph L. Glajch Pdf

This revision brings the reader completely up to date on the evolving methods associated with increasingly more complex sample types analyzed using high-performance liquid chromatography, or HPLC. The book also incorporates updated discussions of many of the fundamental components of HPLC systems and practical issues associated with the use of this analytical method. This edition includes new or expanded treatments of sample preparation, computer assisted method development, as well as biochemical samples, and chiral separations.

Practical HPLC Methodology and Applications

Bidlingmeyer
Practical HPLC Methodology and Applications Book PDF

Author : Bidlingmeyer
Publisher : Unknown
Page : 576 pages
File Size : 48,7 Mb
Release : 2007-08-29
Category : Electronic
ISBN : 0471654418

Get Book

Practical HPLC Methodology and Applications by Bidlingmeyer Pdf

The second edition of this work brings HPLC into the twenty-first century with developments from the last decade. It retains the first edition′s accessibility in providing a guide to getting started with HPLC, but uses more charts and tables to summarize topics and direct decision making. It includes a new chapter on detection options, with all other chapters updated to reflect the latest applications and methodologies. Written by one of the most renowned people working in HPLC, this book is the only guide you need to get started with HPLC and successfully develop applications.

HPLC

Joel K. Swadesh
HPLC Book PDF

Author : Joel K. Swadesh
Publisher : CRC Press
Page : 480 pages
File Size : 51,5 Mb
Release : 2000-12-21
Category : Science
ISBN : 9781420042665

Get Book

HPLC by Joel K. Swadesh Pdf

Product specifications, regulatory constraints, and tight production schedules impose considerable pressures on separation scientists in industry. The first edition of HPLC: Practical and Industrial Applications helped eliminate the need for extensive library or laboratory research when confronting a problem, an unfamiliar technique, or work in a n

Introduction to Modern Liquid Chromatography

Lloyd R. Snyder,Joseph J. Kirkland,John W. Dolan
Introduction to Modern Liquid Chromatography Book PDF

Author : Lloyd R. Snyder,Joseph J. Kirkland,John W. Dolan
Publisher : John Wiley & Sons
Page : 831 pages
File Size : 48,5 Mb
Release : 2011-09-20
Category : Science
ISBN : 9781118210390

Get Book

Introduction to Modern Liquid Chromatography by Lloyd R. Snyder,Joseph J. Kirkland,John W. Dolan Pdf

The latest edition of the authoritative reference to HPLC High-performance liquid chromatography (HPLC) is today the leading technique for chemical analysis and related applications, with an ability to separate, analyze, and/or purify virtually any sample. Snyder and Kirkland's Introduction to Modern Liquid Chromatography has long represented the premier reference to HPLC. This Third Edition, with John Dolan as added coauthor, addresses important improvements in columns and equipment, as well as major advances in our understanding of HPLC separation, our ability to solve problems that were troublesome in the past, and the application of HPLC for new kinds of samples. This carefully considered Third Edition maintains the strengths of the previous edition while significantly modifying its organization in light of recent research and experience. The text begins by introducing the reader to HPLC, its use in relation to other modern separation techniques, and its history, then leads into such specific topics as: The basis of HPLC separation and the general effects of different experimental conditions Equipment and detection The column—the "heart" of the HPLC system Reversed-phase separation, normal-phase chromatography, gradient elution, two-dimensional separation, and other techniques Computer simulation, qualitative and quantitative analysis, and method validation and quality control The separation of large molecules, including both biological and synthetic polymers Chiral separations, preparative separations, and sample preparation Systematic development of HPLC separations—new to this edition Troubleshooting tricks, techniques, and case studies for both equipment and chromatograms Designed to fulfill the needs of the full range of HPLC users, from novices to experts, Introduction to Modern Liquid Chromatography, Third Edition offers the most up-to-date, comprehensive, and accessible survey of HPLC methods and applications available.

HPLC Method Development for Pharmaceuticals

Satinder Ahuja,Henrik Rasmussen
HPLC Method Development for Pharmaceuticals Book PDF

Author : Satinder Ahuja,Henrik Rasmussen
Publisher : Elsevier
Page : 532 pages
File Size : 50,7 Mb
Release : 2011-09-21
Category : Medical
ISBN : 9780080554198

Get Book

HPLC Method Development for Pharmaceuticals by Satinder Ahuja,Henrik Rasmussen Pdf

High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge. Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities) Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase

High-Performance Gradient Elution

Lloyd R. Snyder,John W. Dolan
High Performance Gradient Elution Book PDF

Author : Lloyd R. Snyder,John W. Dolan
Publisher : John Wiley & Sons
Page : 496 pages
File Size : 46,7 Mb
Release : 2007-01-09
Category : Science
ISBN : 9780470055519

Get Book

High-Performance Gradient Elution by Lloyd R. Snyder,John W. Dolan Pdf

Gradient elution demystified Of the various ways in which chromatography is applied today, few have been as misunderstood as the technique of gradient elution, which presents many challenges compared to isocratic separation. When properly explained, however, gradient elution can be less difficult to understand and much easier to use than often assumed. Written by two well-known authorities in liquid chromatography, High-Performance Gradient Elution: The Practical Application of the Linear-Solvent-Strength Model takes the mystery out of the practice of gradient elution and helps remove barriers to the practical application of this important separation technique. The book presents a systematic approach to the current understanding of gradient elution, describing theory, methodology, and applications across many of the fields that use liquid chromatography as a primary analytical tool. This up-to-date, practical, and comprehensive treatment of gradient elution: * Provides specific, step-by-step recommendations for developing a gradient separation for any sample * Describes the best approach for troubleshooting problems with gradient methods * Guides the reader on the equipment used for gradient elution * Lists which conditions should be varied first during method development, and explains how to interpret scouting gradients * Explains how to avoid problems in transferring gradient methods With a focus on the use of linear solvent strength (LSS) theory for predicting gradient LC behavior and separations by reversed-phase HPLC, High-Performance Gradient Elution gives every chromatographer access to this useful tool.

HPLC for Pharmaceutical Scientists

Yuri V. Kazakevich,Rosario LoBrutto
HPLC for Pharmaceutical Scientists Book PDF

Author : Yuri V. Kazakevich,Rosario LoBrutto
Publisher : John Wiley & Sons
Page : 1136 pages
File Size : 41,6 Mb
Release : 2007-02-16
Category : Science
ISBN : 9780470087947

Get Book

HPLC for Pharmaceutical Scientists by Yuri V. Kazakevich,Rosario LoBrutto Pdf

HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.

High Performance Liquid Chromatography

W.J. Lough,I.W. Wainer
High Performance Liquid Chromatography Book PDF

Author : W.J. Lough,I.W. Wainer
Publisher : CRC Press
Page : 292 pages
File Size : 49,7 Mb
Release : 1995-09-30
Category : Science
ISBN : 0751400769

Get Book

High Performance Liquid Chromatography by W.J. Lough,I.W. Wainer Pdf

High performance liquid chromatography (HPLC) has long been recognized as one of the most useful and versatile analytical techniques. It has now progressed from being a highly expensive method of analysis to a routine technique with wide applications. Consequently there is a requirement in many chemistry and chemistry-related courses for students to acquire a detailed understanding of the principles and practice of HPLC. Written in a manner suitable for undergraduate students studying analytical chemistry and learning about chromatographic analytical techniques applied to pharmaceutical analysis, biochemistry and related disciplines, High-performance Liquid Chromatography: Fundamental Principles and Practice introduces the fundamentals of HPLC. Loosely structured in three parts, the text begins with a thorough introduction of the subject and then progresses through the essential knowledge of the instrumentation needed for HPLC. The final part covers with the applications of HPLC in real-world situations. Developed by a team of international experts from a wide cross-section of disciplines, the text is relevant to a wide range of courses.

Introduction to Modern Liquid Chromatography

Lloyd R. Snyder,Joseph J. Kirkland,John W. Dolan
Introduction to Modern Liquid Chromatography Book PDF

Author : Lloyd R. Snyder,Joseph J. Kirkland,John W. Dolan
Publisher : Wiley
Page : 960 pages
File Size : 48,7 Mb
Release : 2009-12-04
Category : Science
ISBN : 9780470508176

Get Book

Introduction to Modern Liquid Chromatography by Lloyd R. Snyder,Joseph J. Kirkland,John W. Dolan Pdf

The latest edition of the authoritative reference to HPLC High-performance liquid chromatography (HPLC) is today the leading technique for chemical analysis and related applications, with an ability to separate, analyze, and/or purify virtually any sample. Snyder and Kirkland's Introduction to Modern Liquid Chromatography has long represented the premier reference to HPLC. This Third Edition, with John Dolan as added coauthor, addresses important improvements in columns and equipment, as well as major advances in our understanding of HPLC separation, our ability to solve problems that were troublesome in the past, and the application of HPLC for new kinds of samples. This carefully considered Third Edition maintains the strengths of the previous edition while significantly modifying its organization in light of recent research and experience. The text begins by introducing the reader to HPLC, its use in relation to other modern separation techniques, and its history, then leads into such specific topics as: The basis of HPLC separation and the general effects of different experimental conditions Equipment and detection The column—the "heart" of the HPLC system Reversed-phase separation, normal-phase chromatography, gradient elution, two-dimensional separation, and other techniques Computer simulation, qualitative and quantitative analysis, and method validation and quality control The separation of large molecules, including both biological and synthetic polymers Chiral separations, preparative separations, and sample preparation Systematic development of HPLC separations—new to this edition Troubleshooting tricks, techniques, and case studies for both equipment and chromatograms Designed to fulfill the needs of the full range of HPLC users, from novices to experts, Introduction to Modern Liquid Chromatography, Third Edition offers the most up-to-date, comprehensive, and accessible survey of HPLC methods and applications available.

Ultra-High Performance Liquid Chromatography and Its Applications

Q. Alan Xu
Ultra High Performance Liquid Chromatography and Its Applications Book PDF

Author : Q. Alan Xu
Publisher : John Wiley & Sons
Page : 342 pages
File Size : 41,6 Mb
Release : 2013-04-01
Category : Technology & Engineering
ISBN : 9781118533987

Get Book

Ultra-High Performance Liquid Chromatography and Its Applications by Q. Alan Xu Pdf

Explores both the benefits and limitations of new UHPLC technology High performance liquid chromatography (HPLC) has been widely used in analytical chemistry and biochemistry to separate, identify, and quantify compounds for decades. The science of liquid chromatography, however, was revolutionized a few years ago with the advent of ultra-high performance liquid chromatography (UHPLC), which made it possible for researchers to analyze sample compounds with greater speed, resolution, and sensitivity. Ultra-High Performance Liquid Chromatography and Its Applications enables readers to maximize the performance of UHPLC as well as develop UHPLC methods tailored to their particular research needs. Readers familiar with HPLC methods will learn how to transfer these methods to a UHPLC platform and vice versa. In addition, the book explores a variety of UHPLC applications designed to support research in such fields as pharmaceuticals, food safety, clinical medicine, and environmental science. The book begins with discussions of UHPLC method development and method transfer between HPLC and UHPLC platforms. It then examines practical aspects of UHPLC. Next, the book covers: Coupling UHPLC with mass spectrometry Potential of shell particles in fast liquid chromatography Determination of abused drugs in human biological matrices Analyses of isoflavones and flavonoids Therapeutic protein characterization Analysis of illicit drugs The final chapter of the book explores the use of UHPLC in drug metabolism and pharmacokinetics studies for traditional Chinese medicine. With its frank discussions of UHPLC's benefits and limitations, Ultra-High Performance Liquid Chromatography and Its Applications equips analytical scientists with the skills and knowledge needed to take full advantage of this new separation technology.

Selection of the HPLC Method in Chemical Analysis

Serban C. Moldoveanu,Victor David
Selection of the HPLC Method in Chemical Analysis Book PDF

Author : Serban C. Moldoveanu,Victor David
Publisher : Elsevier
Page : 598 pages
File Size : 49,5 Mb
Release : 2016-11-01
Category : Science
ISBN : 9780128037119

Get Book

Selection of the HPLC Method in Chemical Analysis by Serban C. Moldoveanu,Victor David Pdf

Selection of the HPLC Method in Chemical Analysis serves as a practical guide to users of high-performance liquid chromatography and provides criteria for method selection, development, and validation. High-performance liquid chromatography (HPLC) is the most common analytical technique currently practiced in chemistry. However, the process of finding the appropriate information for a particular analytical project requires significant effort and pre-existent knowledge in the field. Further, sorting through the wealth of published data and literature takes both time and effort away from the critical aspects of HPLC method selection. For the first time, a systematic approach for sorting through the available information and reviewing critically the up-to-date progress in HPLC for selecting a specific analysis is available in a single book. Selection of the HPLC Method in Chemical Analysis is an inclusive go-to reference for HPLC method selection, development, and validation. Addresses the various aspects of practice and instrumentation needed to obtain reliable HPLC analysis results Leads researchers to the best choice of an HPLC method from the overabundance of information existent in the field Provides criteria for HPLC method selection, development, and validation Authored by world-renowned HPLC experts who have more than 60 years of combined experience in the field

Modern HPLC for Practicing Scientists

Michael W. Dong
Modern HPLC for Practicing Scientists Book PDF

Author : Michael W. Dong
Publisher : John Wiley & Sons
Page : 328 pages
File Size : 49,9 Mb
Release : 2016-04-06
Category : Science
ISBN : 9781119293606

Get Book

Modern HPLC for Practicing Scientists by Michael W. Dong Pdf

A comprehesive yet concise guide to Modern HPLC Written for practitioners by a practitioner, Modern HPLC for Practicing Scientists is a concise text which presents the most important High-Performance Liquid Chromatography (HPLC) fundamentals, applications, and developments. It describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. Moreover, the book serves well as an updated reference guide for busy laboratory analysts and researchers. Topics covered include: HPLC operation Method development Maintenance and troubleshooting Modern trends in HPLC such as quick-turnaround and "greener" methods Regulatory aspects While broad in scope, this book focuses particularly on reversed-phase HPLC, the most common separation mode, and on applications for the pharmaceutical industry, the largest user segment. Accessible to both novice and intermedate HPLC users, information is delivered in a straightforward manner illustrated with an abundance of diagrams, chromatograms, tables, and case studies, and supported with selected key references and Web resources. With intuitive explanations and clear figures, Modern HPLC for Practicing Scientists is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology.

Practice of High Performance Liquid Chromatography

Heinz Engelhardt
Practice of High Performance Liquid Chromatography Book PDF

Author : Heinz Engelhardt
Publisher : Springer Science & Business Media
Page : 468 pages
File Size : 50,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642692253

Get Book

Practice of High Performance Liquid Chromatography by Heinz Engelhardt Pdf

During its short 20 year history High Performance Liquid Chro matography (HPLC) has won itself a firm place amongst the instrumental methods of analysis. HPLC has caused a revolution in biological and pharmaceutical chemistry. Approximately two thirds of the publications on HPLC are concerned with problems from this area of life science. Biotechnology, where it is necessary to isolate substances from complicated mixtures, is likely to give further impetus to the dissemination of modern liquid chromatog raphy in columns, particularly on the preparative scale. This book presents, by means of examples, the application of HPLC to various fields, as well as fundamental discussions of chromatographic methods. The quality of the analytical result is decisively dependent on the qualities of the equipment employed (by Colin, Guiochon, and Martin). Especially the demands are discussed that are placed on the components of the instrument including those for data acquisition and processing. The section on "quantitative analy sis" (by ABhauer, Ullner) covers besides the principles also the problems of ensuring the quality of the data in detail. The basic problems arising by enlarging the sample size to preparative di mensions and the requirements put on the aparatus are discussed in the section on "preparative applications" (by Wehrli).

HPLC Made to Measure

Stavros Kromidas
HPLC Made to Measure Book PDF

Author : Stavros Kromidas
Publisher : John Wiley & Sons
Page : 786 pages
File Size : 54,6 Mb
Release : 2008-06-05
Category : Science
ISBN : 9783527611997

Get Book

HPLC Made to Measure by Stavros Kromidas Pdf

The only topical HPLC book to focus on optimization, this volume addresses the needs of HPLC users who wish to constantly improve their methods, in particular in terms of throughput, accuracy and cost-effectiveness. This handbook features contributions from such bestselling authors as John W. Dolan, Michael McBrien, Veronika R. Meyer, Uwe D. Neue, Lloyd R. Snyder, and Klaus K. Unger, as well as from scientists working for major companies, including Agilent, AstraZeneca, Merck, Schering, Tosoh Biosep, VWR, and Waters. It covers essential aspects of optimization in general, optimization in different LC-modi, hyphenated techniques and computer-aided optimization. The whole is rounded off with a section of user reports.