Precision Public Health

Author : Tarun Weeramanthri,Hugh Dawkins,Gareth Baynam,Matthew Bellgard,Ori Gudes,James Semmens
Publisher : Frontiers Media SA
Page : 149 pages
File Size : 54,9 Mb
Release : 2018-06-25
Category : Electronic
ISBN : 9782889455010

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Precision Public Health by Tarun Weeramanthri,Hugh Dawkins,Gareth Baynam,Matthew Bellgard,Ori Gudes,James Semmens Pdf

Precision Public Health is a new and rapidly evolving field, that examines the application of new technologies to public health policy and practice. It draws on a broad range of disciplines including genomics, spatial data, data linkage, epidemiology, health informatics, big data, predictive analytics and communications. The hope is that these new technologies will strengthen preventive health, improve access to health care, and reach disadvantaged populations in all areas of the world. But what are the downsides and what are the risks, and how can we ensure the benefits flow to those population groups most in need, rather than simply to those individuals who can afford to pay? This is the first collection of theoretical frameworks, analyses of empirical data, and case studies to be assembled on this topic, published to stimulate debate and promote collaborative work.

Author : Lloyd Minor
Publisher : John Wiley & Sons
Page : 267 pages
File Size : 44,5 Mb
Release : 2020-01-23
Category : Medical
ISBN : 9781119672746

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Discovering Precision Health by Lloyd Minor Pdf

Today we are on the brink of a much-needed transformative moment for health care. The U.S. health care system is designed to be reactive instead of preventive. The result is diagnoses that are too late and outcomes that are far worse than our level of spending should deliver. In recent years, U.S. life expectancy has been declining. Fundamental to realizing better health, and a more effective health care system, is advancing the disruptive thinking that has spawned innovation in Silicon Valley and throughout the world. That's exactly what Stanford Medicine has done by proposing a new vision for health and health care. In Discovering Precision Health, Lloyd Minor and Matthew Rees describe a holistic approach that will set health care on the right track: keep people healthy by preventing disease before it starts and personalize the treatment of individuals precisely, based on their specific profile. With descriptions of the pioneering work undertaken at Stanford Medicine, complemented by fascinating case studies of innovations from entities including the Chan Zuckerberg Biohub, GRAIL, and Impossible Foods, Minor and Rees present a dynamic vision for the future of individual health and health care. Youll see how tools from smartphone technology to genome sequencing to routine blood tests are helping avert illness and promote health. And you'll learn about the promising progress already underway in bringing greater precision to the process of predicting, preventing, and treating a range of conditions, including allergies, mental illness, preterm birth, cancer, stroke, and autism. The book highlights how biomedical advances are dramatically improving our ability to treat and cure complex diseases, while emphasizing the need to devote more attention to social, behavioral, and environmental factors that are often the primary determinants of health. The authors explore thought-provoking topics including: The unlikely role of Google Glass in treating autism How gene editing can advance precision in treating disease What medicine can learn from aviation liHow digital tools can contribute to health and innovation Discovering Precision Health showcases entirely new ways of thinking about health and health care and can help empower us to lead healthier lives.

Author : Bechara Choucair
Publisher : Island Press
Page : 224 pages
File Size : 55,5 Mb
Release : 2020-05-28
Category : Social Science
ISBN : 9781642830163

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Precision Community Health by Bechara Choucair Pdf

When Bechara Choucair was a young doctor, he learned an important lesson: treating a patient for hypothermia does little good if she has to spend the next night out in the freezing cold. As health commissioner of Chicago, he was determined to address the societal causes of disease and focus the city’s resources on its most vulnerable populations. That targeted approach has led to dramatic successes, such as lowering rates of smoking, teen pregnancy, breast cancer mortalities, and other serious ills. In Precision Community Health, Choucair shows how those successes can be replicated and expanded around the country. The key is to use advanced technologies to identify which populations are most at risk for specific health threats and avert crises before they begin. Big data makes precision community health possible. But in our increasingly complex world, we also need new strategies for developing effective coalitions, media campaigns, and policies. This book showcases four innovations that move public health departments away from simply dispensing medical care and toward supporting communities to achieve true well-being. The approach Choucair pioneered in Chicago requires broadening our thinking about what constitutes public health. It is not simply about access to a doctor, but access to decent housing, jobs, parks, food, and social support. It also means acknowledging that a one-size-fits-all strategy may exacerbate inequities. By focusing on those most in need, we create an agenda that is simultaneously more impactful and more achievable. The result is a wholesale change in the way public health is practiced and in the well-being of all our communities.

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on A Framework for Developing a New Taxonomy of Disease
Publisher : National Academies Press
Page : 142 pages
File Size : 48,6 Mb
Release : 2012-01-16
Category : Medical
ISBN : 9780309222228

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Toward Precision Medicine by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on A Framework for Developing a New Taxonomy of Disease Pdf

Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Author : Ernst R. Berndt,Dana P. Goldman,John Rowe
Publisher : University of Chicago Press
Page : 361 pages
File Size : 42,8 Mb
Release : 2019-04-22
Category : Business & Economics
ISBN : 9780226611068

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Economic Dimensions of Personalized and Precision Medicine by Ernst R. Berndt,Dana P. Goldman,John Rowe Pdf

Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.

Author : John Snow
Publisher : Unknown
Page : 74 pages
File Size : 47,8 Mb
Release : 1849
Category : Cholera
ISBN : BL:A0018134513

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On the Mode of Communication of Cholera by John Snow Pdf

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 42,9 Mb
Release : 2018
Category : Electronic
ISBN : OCLC:1368443890

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Precision Public Health by Anonim Pdf

Precision Public Health is a new and rapidly evolving field, that examines the application of new technologies to public health policy and practice. It draws on a broad range of disciplines including genomics, spatial data, data linkage, epidemiology, health informatics, big data, predictive analytics and communications. The hope is that these new technologies will strengthen preventive health, improve access to health care, and reach disadvantaged populations in all areas of the world. But what are the downsides and what are the risks, and how can we ensure the benefits flow to those population groups most in need, rather than simply to those individuals who can afford to pay? This is the first collection of theoretical frameworks, analyses of empirical data, and case studies to be assembled on this topic, published to stimulate debate and promote collaborative work.

Author : Joel Faintuch,Salomao Faintuch
Publisher : Academic Press
Page : 640 pages
File Size : 51,7 Mb
Release : 2019-11-16
Category : Science
ISBN : 9780128191798

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Precision Medicine for Investigators, Practitioners and Providers by Joel Faintuch,Salomao Faintuch Pdf

Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers Covers disease groups and ancillary information about techniques, resources and consequences Follows a structured blueprint, ensuring essential chapters items are not overlooked

Author : Mukesh Verma,Debmalya Barh
Publisher : Academic Press
Page : 344 pages
File Size : 46,8 Mb
Release : 2016-12-22
Category : Medical
ISBN : 9780128095027

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Progress and Challenges in Precision Medicine by Mukesh Verma,Debmalya Barh Pdf

Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development

Author : Rhiannon Tudor Edwards,Emma McIntosh
Publisher : Oxford University Press
Page : 400 pages
File Size : 52,5 Mb
Release : 2019-03-14
Category : Medical
ISBN : 9780191057236

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Applied Health Economics for Public Health Practice and Research by Rhiannon Tudor Edwards,Emma McIntosh Pdf

In today's world of scare resources, determining the optimal allocation of funds to preventive health care interventions (PHIs) is a challenge. The upfront investments needed must be viewed as long term projects, the benefits of which we will experience in the future. The long term positive change to PHIs from economic investment can be seen across multiple sectors such as health care, education, employment and beyond. Applied Health Economics for Public Health Practice and Research is the fifth in the series of Handbooks in Health Economic Evaluation. It presents new research on health economics methodology and application to the evaluation of public health interventions. Looking at traditional as well as novel methods of economic evaluation, the book covers the history of economics of public health and the economic rationale for government investment in prevention. In addition, it looks at principles of health economics, evidence synthesis, key methods of economic evaluation with accompanying case studies, and much more. Looking to the future, Applied Health Economics for Public Health Practice and Research presents priorities for research in the field of public health economics. It acknowledges the role played by natural environment in promoting better health, and the place of genetics, environment and socioeconomic status in determining population health. Ideal for health economists, public health researchers, local government workers, health care professionals, and those responsible for health policy development. Applied Health Economics for Public Health Practice and Research is an important contribution to the economic discussion of public health and resource allocation.

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Roundtable on Health Literacy
Publisher : National Academies Press
Page : 125 pages
File Size : 55,8 Mb
Release : 2016-12-04
Category : Medical
ISBN : 9780309447324

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Relevance of Health Literacy to Precision Medicine by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Roundtable on Health Literacy Pdf

On January 20, 2015, President Obama announced the Precision Medicine Initiative (PMI) in his State of the Union address. The PMI, by developing new approaches for detecting, measuring, and analyzing a wide range of biomedical information including molecular, genomic, cellular, clinical, behavioral, physiological, and environmental parameters, is intended to enable a new era of medicine in which researchers, providers, and patients work together to develop individualized care. Part of this effort included the creation of a national, large-scale research participant group, or cohort. The PMI Cohort Program is aimed at extending precision medicine to many diseases, including both rare and common diseases such as diabetes, heart disease, Alzheimer's disease, obesity, and mental illnesses such as depression, bipolar disorder, and schizophrenia, by building a national research cohort of 1 million or more U.S. participants. An important challenge to assembling the PMI Cohort will be to reach individuals who are socioeconomically disadvantaged. Individuals who are socioeconomically disadvantaged have lower health literacy; often belong to racial, ethnic, and minority communities; and are often less likely to participate in research studies and biorepositories. To explore possible strategies and messaging designs, the Roundtable on Health Literacy formed an ad hoc committee charged with planning and conducting a 1-day public workshop on the intersection of health literacy and precision medicine. The workshop participants discussed a variety of topics including an overview of precision medicine and its potential, the relevance of health literacy to the success of precision medicine efforts, and perspectives and understanding of different groups, such as health care providers, consumers, and insurers. This publication summarizes the presentations and discussions from the workshop.

Author : Geoffrey S. Ginsburg,Huntington F Willard,John Strickler,Matthew Stuart McKinney
Publisher : Academic Press
Page : 379 pages
File Size : 48,5 Mb
Release : 2022-04-09
Category : Science
ISBN : 9780128006535

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Genomic and Precision Medicine by Geoffrey S. Ginsburg,Huntington F Willard,John Strickler,Matthew Stuart McKinney Pdf

Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field. Provides a comprehensive volume written and edited by oncology genomic specialists for oncology health providers Includes succinct commentary and key learning points that will assist providers with their local needs for implementation of genomic and personalized medicine into practice Presents an up-to-date overview on major opportunities for genomic and personalized medicine in practice Covers case studies that highlight the practical use of genomics in the management of patients

Author : Soundappan Kathirvel,Amarjeet Singh,Arun Chockalingam
Publisher : Elsevier
Page : 356 pages
File Size : 44,5 Mb
Release : 2023-09-01
Category : Science
ISBN : 9780323953559

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Principles and Application of Evidence-Based Public Health Practice by Soundappan Kathirvel,Amarjeet Singh,Arun Chockalingam Pdf

Principles and Application of Evidence-Based Public Health Practice helps clinicians who conduct population-based studies in the community be aware of the principles and ethics involved in public health research. Further, the book helps social scientists involved in public health, especially regarding the medical implication of public health practice. Community-based epidemiological research studies are vital for any public health activities, be it evaluation of health programs, health systems strengthening, surveillance or preventive/promotive trials in the community. While hospital/clinic-based research is conducted in a very controlled setting, community trials are more practical. Community-based studies require a fairly different set of ethical and epidemiological principles to be followed. The same has been reiterated in the ethical guidelines for biomedical research on human subjects released by various national research organizations. Assists the reader in understanding various strategies taken during any public health emergency Uses case studies to discuss the strategies to be considered during the preparedness and management of public health emergencies Helps build capacity and enhance quality of services delivered as part of public health practice

Author : Jules J. Berman
Publisher : Academic Press
Page : 398 pages
File Size : 53,8 Mb
Release : 2018-01-26
Category : Business & Economics
ISBN : 9780128143940

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Precision Medicine and the Reinvention of Human Disease by Jules J. Berman Pdf

Despite what you may have read in the popular press and in social media, Precision Medicine is not devoted to finding unique treatments for individuals, based on analyzing their DNA. To the contrary, the goal of Precision Medicine is to find general treatments that are highly effective for large numbers of individuals who fall into precisely diagnosed groups. We now know that every disease develops over time, through a sequence of defined biological steps, and that these steps may differ among individuals, based on genetic and environmental conditions. We are currently developing rational therapies and preventive measures, based on our precise understanding of the steps leading to the clinical expression of diseases. Precision Medicine and the Reinvention of Human Disease explains the scientific breakthroughs that have changed the way that we understand diseases, and reveals how medical scientists are using this new knowledge to launch a medical revolution. Clarifies the foundational concepts of Precision Medicine, distinguishing this field from its predecessors such as genomics, pharmacogenetics, and personalized medicine. Gathers the chief conceptual advances in the fields of genetics, pathology, and bioinformatics, and synthesizes a coherent narrative for the field of Precision Medicine. Delivers its message in plain language, and in a relaxed, conversational writing style, making it easy to understand the complex subject matter. Guides the reader through a coherent and logical narrative, gradually providing expertise and skills along the way. Covers the importance of data sharing in Precision Medicine, and the many data-related challenges that confront this fragile new field.

Author : Seth S. Martin
Publisher : Springer Nature
Page : 194 pages
File Size : 54,9 Mb
Release : 2021-07-07
Category : Medical
ISBN : 9783030750558

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Precision Medicine in Cardiovascular Disease Prevention by Seth S. Martin Pdf

This book contains the current knowledge and potential future developments of precision medicine techniques including artificial intelligence, big data, mobile health, digital health and genetic medicine in the prevention of cardiovascular disease. It reviews the presently used advanced precision medicine techniques and fundamental principles that continue to act as guiding forces for many medical professionals in applying precision and preventative medical techniques in their day-to-day practices. Precision Medicine in Cardiovascular Disease Prevention describes current knowledge and potential future developments in this rapidly expanding field. It therefore provides a valuable resource for all practicing and trainee cardiologists looking to develop their knowledge and integrate precision medicine techniques into their practices.