Reagents For Glycoside Nucleotide And Peptide Synthesis

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Reagents for Glycoside, Nucleotide, and Peptide Synthesis

Author : David Crich
Publisher : Wiley
Page : 792 pages
File Size : 42,8 Mb
Release : 2005-10-21
Category : Science
ISBN : 047002304X

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Reagents for Glycoside, Nucleotide, and Peptide Synthesis by David Crich Pdf

This handbook collects together short, informative articles on approximately 250 of the most widely used reagents in the field, into a single volume. Each of the articles, drawn from the e-EROS database, contains a summary of the most pertinent reactions for every reagent, with references to the original literature. This handbook will have a broad appeal and should find a home in every organic chemistry laboratory and library. Compiles all the essential reagents for syntheses on and with biomolecules Gives key information on protection, bond formation and deprotection An essential resource for all synthetic chemists working in drug development and medicinal chemistry Makes use of the leading reagent database e-EROS

Handbook of Reagents for Organic Synthesis

Author : André B. Charette
Publisher : John Wiley & Sons
Page : 824 pages
File Size : 51,7 Mb
Release : 2015-07-15
Category : Science
ISBN : 9781118726556

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Handbook of Reagents for Organic Synthesis by André B. Charette Pdf

Heteroarenes are among the most prevalent structural units in natural products, pharmaceuticals, agrochemicals, and other compounds of scientific or commercial interest. In the last decade, a broad range of novel synthetic methods has been developed to not only facilitate construction of the heteroarene motif, but to enable its modification through direct C–H functionalization. This Handbook describes 117 key reagents for selective heteroarene functionalization reactions, including both traditional and transition metal-catalyzed C–H functionalization. Since these reactions typically involve one heteroarene, a coupling partner and a catalyst, the handbook not only focuses on the catalyst itself but also contains other key reaction species. All the information compiled in this volume is also available in electronic format on Wiley Online Library. The 117 reagents represented here are but a small fraction of the ca. 5,000 reagents available in the electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). e-EROS offers various search interfaces to locate reagents of interest, including chemical structure, substructure and reactions search modes. e-EROS is updated regularly with new and updated entries.

Reagents for Silicon-Mediated Organic Synthesis

Author : Philip L. Fuchs
Publisher : John Wiley & Sons
Page : 816 pages
File Size : 53,5 Mb
Release : 2013-05-30
Category : Technology & Engineering
ISBN : 9781118636138

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Reagents for Silicon-Mediated Organic Synthesis by Philip L. Fuchs Pdf

Over the last three decades the importance of organosiliconchemistry has greatly increased because it has opened a number ofnew synthetic strategies. Silicon reagents are usually low-cost,versatile and allow a wide range of reactions. This is the firstHandbook to compile essential Silicon containing reagents and makesuse of the leading reagent database e-EROS. Another hotvolume in the series Handbooks of Reagents for OrganicSynthesis, this is a must-have resource for all syntheticchemists working in drug development and medicinal chemistry. For the selection the Editor focussed on three key syntheticapproaches with the greatest impact: 1. Use of silicon as a 'temporary tether' by unifying a reactivepair of functional groups and taking advantage of theirtemplate-biased intramolecular cyclization. 2. The specific use of the silane functionality as a heterot-butyl group, often colloquially referred to as the use ofsilicon as a 'fat proton'. 3. The use of the Brook rearrangement as an 'anion relaystratagem'. A new feature in this Handbook is the reagent finder, analphabetically organized lookup table arranged by organicfunctionality and specific structure of the silicon atom to whichit is bound.

Handbook of Reagents for Organic Synthesis

Author : Tomislav Rovis
Publisher : John Wiley & Sons
Page : 725 pages
File Size : 48,7 Mb
Release : 2016-10-17
Category : Science
ISBN : 9781119061007

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Handbook of Reagents for Organic Synthesis by Tomislav Rovis Pdf

Spurred by the desire to make chemistry a sustainable and "greener" technology, the field of organocatalysis has grown to become one of the most important areas in synthetic organic chemistry. Organic catalysts can often replace potentially toxic metal catalysts and allow reactions to proceed under mild reaction conditions, thereby saving energy costs and rendering chemical processes inherently safer. More importantly perhaps, organocatalysis offers a complementary reactivity in many instances leading to increased versatility. This Handbook describes 126 key reagents for organocatalytic reactions and will be especially useful for professionals in the area of sustainable chemistry, medicinal research, as well as synthetic organic chemists working in academia and the pharmaceutical industry. All the information compiled in this volume is also available in electronic format on Wiley Online Library. The 126 reagents represented here are but a small fraction of the ca. 5,000 reagents available in the electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). e-EROS offers various search interfaces to locate reagents of interest, including chemical structure, substructure and reactions search modes. e-EROS is updated regularly with new and updated entries.

Sulfur-Containing Reagents

Author : Leo A. Paquette
Publisher : John Wiley & Sons
Page : 1957 pages
File Size : 42,8 Mb
Release : 2013-05-30
Category : Science
ISBN : 9781118634868

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Sulfur-Containing Reagents by Leo A. Paquette Pdf

There are a lot of books available about the chemistry and biology of sulfur. However, this is the first book with a compilation of all relevant Sulfur containing reagents. Synthetic chemists, most particularly in the medicinal and pharmaceutical chemists, are often called upon to prepare compounds that contain Sulfur as a key structural feature. In the past, this seemed to be a domain for specialists; today every synthetic chemist working in these area is expected to synthesize compounds containing sulfides, sulfates, sulfones, etc. This book offers an important source of information for the selection and handling of the right reagents.

Catalytic Oxidation Reagents

Author : Philip L. Fuchs
Publisher : John Wiley & Sons
Page : 2037 pages
File Size : 44,9 Mb
Release : 2013-07-29
Category : Science
ISBN : 9781118704844

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Catalytic Oxidation Reagents by Philip L. Fuchs Pdf

The Handbook is part of the Handbook of Reagents for Organic Chemistry series, aiming at collecting articles on a particular theme that individual researchers in academia or industry can use on a daily basis. The Handbook starts with a section discussing the most important aspects of heteroarene functionalization. The introduction is followed by the alphabetical listing of the most relevant reagents drawn from the EROS database. The Editor, André Charette from the University of Montreal, has selected 120 reagent descriptions, many of them updated with heteroarene-specific reactions for this Handbook. Following the standard format for EROS, each article contains an overview of the synthesis and physical properties of the reagents or catalyst, conditions for its storage, and purification methods. Given the importance of heteroarenes in biology and especially in medicinal chemistry, a Handbook that focuses exclusively on heteroarene functionalization has been long overdue. This Handbook will have a broad appeal to many individuals engaged in the area of medicinal chemistry, fine chemical synthesis and industrial-scale chemistry. Key features: Builds on the success of the previously published Handbooks of Reagents for Organic Synthesis Compares the numerous new C-H functionalization reactions that have been developed in the past decade Heteroarene functionalization is widely used in the development of pharmaceuticals and other bioactive compounds Contains listings of secondary reagents for which more information is available in the online edition

Reagents for Radical and Radical Ion Chemistry

Author : David Crich
Publisher : John Wiley & Sons
Page : 1874 pages
File Size : 47,7 Mb
Release : 2013-05-30
Category : Science
ISBN : 9781118634899

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Reagents for Radical and Radical Ion Chemistry by David Crich Pdf

Radicals and radical ions are important intermediates with wide use in organic synthesis. The first book to concentrate on reagents for the creation and use of radicals and radical ions, this new volume in the Handbooks of Reagents for Organic Synthesis series compiles articles taken from the e-eros database, on reagents for use in radical and radical chemistry, to help the chemist in the lab choose the right reagents. Reflecting the enormous growth of radical chemistry over the past ten years, this is an essential guide for all synthetic chemists.

The Power of Functional Resins in Organic Synthesis

Author : Fernando Albericio,Judit Tulla-Puche
Publisher : John Wiley & Sons
Page : 683 pages
File Size : 47,6 Mb
Release : 2008-12-17
Category : Science
ISBN : 9783527626182

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The Power of Functional Resins in Organic Synthesis by Fernando Albericio,Judit Tulla-Puche Pdf

While many books cover solid phase synthesis and combinatorial synthesis, this one is unique in its exclusive coverage of the other aspects of solid-phase synthesis. As such, it contains everything you need to know -- from supported reagents, to scavengers, resins, and the synthesis of biomolecules and natural products. An invaluable companion for all chemists and biochemists working in university research and industry.

Catalyst Components for Coupling Reactions

Author : Gary A. Molander
Publisher : John Wiley & Sons
Page : 1749 pages
File Size : 50,6 Mb
Release : 2013-05-30
Category : Science
ISBN : 9781118643433

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Catalyst Components for Coupling Reactions by Gary A. Molander Pdf

The long awaited Handbook for all synthetic chemists working on coupling reactions, compiling all major catalyst components in use in the area. Consists of a compilation of articles taken from the EROS database, with the inclusion of about 20 newly commissioned catalysts/pre-catalysts/ligands that have made an impact in this area of synthetic organic chemistry. Includes catalyst systems used in Heck, Kumada-Tamao-Corriu, Suzuki-Miyaura, Hiyama-Hatanaka, Negishi, Migita-Kosugi-Stille, Buchwald-Hartwig, and Tsuji-Trost coupling reactions.

Organic Chemist's Desk Reference

Author : Caroline Cooper,Rupert Purchase
Publisher : CRC Press
Page : 296 pages
File Size : 51,6 Mb
Release : 2017-08-04
Category : Medical
ISBN : 9781498734028

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Organic Chemist's Desk Reference by Caroline Cooper,Rupert Purchase Pdf

Launched in 1995 as a companion to the Dictionary of Organic Compounds, the Organic Chemist’s Desk Reference has been essential reading for laboratory chemists who need a succinct guide to the ‘nuts and bolts’ of organic chemistry — the literature, nomenclature, stereochemistry, spectroscopy, hazard information, and laboratory data. This third edition reflects changes in the dissemination of chemical information, revisions to chemical nomenclature, and the adoption of new techniques in NMR spectroscopy, which have taken place since publication of the last edition in 2011. Organic chemistry embraces many other disciplines — from material sciences to molecular biology — whose practitioners will benefit from the comprehensive but concise information brought together in this book. Extensively revised and updated, this new edition contains the very latest data that chemists need access to for experimentation and research.

Carbohydrates: The Essential Molecules of Life

Author : Robert V. Stick,Spencer Williams
Publisher : Elsevier
Page : 496 pages
File Size : 42,9 Mb
Release : 2010-08-06
Category : Science
ISBN : 0080927025

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Carbohydrates: The Essential Molecules of Life by Robert V. Stick,Spencer Williams Pdf

This book provides the "nuts and bolts" background for a successful study of carbohydrates - the essential molecules that not only give you energy, but are an integral part of many biological processes. A question often asked is 'Why do carbohydrate chemistry?' The answer is simple: It is fundamental to a study of biology. Carbohydrates are the building blocks of life and enable biological processes to take place. Therefore the book will provide a taste for the subject of glycobiology. Covering the basics of carbohydrates and then the chemistry and reactions of carbohydrates this book will enable a chemist to gain essential knowledge that will enable them to move smoothly into the worlds of biochemistry, molecular biology and cell biology. * includes perspective from new co-author Spencer Williams, who enhances coverage of the connection between carbohydrates and life * describes the basic chemistry and biology of carbohydrates * reviews the concepts, synthesis, reactions, and biology of carbohydrates

Essentials of Carbohydrate Chemistry and Biochemistry

Author : Thisbe K. Lindhorst
Publisher : John Wiley & Sons
Page : 333 pages
File Size : 46,5 Mb
Release : 2007-04-09
Category : Science
ISBN : 9783527315284

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Essentials of Carbohydrate Chemistry and Biochemistry by Thisbe K. Lindhorst Pdf

Concise yet complete, this is a succinct introduction to the topic, covering both basic chemistry as well as such advanced topics as high-throughput analytics and glycomics -- in one handy volume. This improved and expanded 3rd edition features all-new material on combinatorial synthesis of carbohydrates and carbohydrate biodiversity, and each chapter now contains study questions for self-learning and classroom teaching. Didactically written by an experienced lecturer and graduate student advisor, the text is backed by practical examples and more than 150 study questions tailored to students' needs.

Molten Salts and Ionic Liquids 17

Author : D. M. Fox
Publisher : The Electrochemical Society
Page : 710 pages
File Size : 41,7 Mb
Release : 2010-10
Category : Science
ISBN : 9781566778268

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Molten Salts and Ionic Liquids 17 by D. M. Fox Pdf

This issue of ECS Transactions presents the latest research on systems and processes involving molten salts and room temperature ionic liquids. The studies compiled include both basic and applied research covering a wide range of topics. The main topics discussed in this volume include solution properties; reactions and separations; biochemical, biomedical, and green processes; electrodeposition; electrochemical power; corrosion and other electrochemical processes; and nuclear chemistry.

Carbohydrate Chemistry

Author : Pavol Kováč
Publisher : CRC Press
Page : 470 pages
File Size : 45,9 Mb
Release : 2011-09-22
Category : Medical
ISBN : 9781439866894

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Carbohydrate Chemistry by Pavol Kováč Pdf

Long gone are the days when synthetic publications included parallel preparative experiments to document reproducibility of the experimental protocols and when journals required such documentation. The new Proven Synthetic Methods Series addresses concerns to chemists regarding irreproducibility of synthetic protocols, lack of characterization data for new compounds, and inflated yields reported in many chemical communications—trends that have recently become a serious problem. Volume One of Carbohydrate Chemistry: Proven Synthetic Methods includes more detailed versions of protocols previously published for the synthesis of oligosaccharides, C-glycosyl compounds, sugar nucleotides, click chemistry, thioglycosides, and thioimidates, among others. The compilation of protocols covers both common and less frequently used synthetic methods as well as examples of syntheses of selected carbohydrate intermediates with general utility. The major focus of this book is devoted to the proper practice of state-of-the-art preparative procedures, including: References to the starting materials used, reaction setup, work-up and isolation of products, followed by identification and proof of purity of the final material General information regarding convenience of operation and comments on safety issues Versatile and practically useful methods that have not received deserved, long-lasting recognition or that are difficult to access from their primary sources Copies of 1D NMR spectra of compounds prepared, showing purity of materials readers can expect Exploring carbohydrate chemistry from the academic points of view, the Carbohydrate Chemistry: Proven Synthetic Methods Series provides a compendium of preparatively useful procedures checked by chemists from independent research groups.

Handbook of Chemical Glycosylation

Author : Alexei V. Demchenko
Publisher : John Wiley & Sons
Page : 524 pages
File Size : 48,6 Mb
Release : 2008-04-09
Category : Science
ISBN : 9783527621651

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Handbook of Chemical Glycosylation by Alexei V. Demchenko Pdf

Since carbohydrate oligomers are still a challenge in synthetic chemistry, this book on recent developments fulfils a great need. Covering the chemistry necessary to synthesize exact copies of these structures, top authors from all around the world comprehensively deal with synthesis from anomeric halides, from miscellaneous glycosyl donors, and by indirect and special methods, as well as 1-oxygen-and 1-sulfur-substituted derivatives. They demonstrate the best approach for the stereoselective formation of the intermonomeric bond, making this essential reading for every biochemist working in biosynthesis, the exploration of biopathways and vaccines.