Recent Advances In The Application Of Marine Natural Products As Antimicrobial Agents

Author : Arumugam Veera Ravi,Ramanathan Srinivasan,Arunachalam Kannappan
Publisher : Bentham Science Publishers
Page : 436 pages
File Size : 44,6 Mb
Release : 2023-10-02
Category : Medical
ISBN : 9789815080155

Get Book

Recent Advances in the Application of Marine Natural Products as Antimicrobial Agents by Arumugam Veera Ravi,Ramanathan Srinivasan,Arunachalam Kannappan Pdf

While the world is grappling with the growing problem of antibiotic resistance, marine organisms offer a promising solution with their diverse repertoire of bioactive compounds. This thematic volume explores the untapped potential of marine organisms in the fight against microbial threats. The focus of the 17 featured chapters lies in highlighting the vast array of antimicrobial agents that can be found within marine environments. The chapters provide in-depth knowledge about the latest discoveries, advancements and future needs in antimicrobial research. Readers will learn about astonishing discoveries of natural compounds with remarkable antimicrobial properties and sources. The list of agents covered in the book includes synthetic derivatives, bioactive polysaccharides and marine viruses. The book also includes chapters that cover various stages of the antimicrobial drug development process, providing an overview of recent antimicrobial agents derived from marine organisms, preclinical studies and the identification of patented drugs sourced from the ocean. Furthermore, the book sheds light on the diverse applications of these marine-derived compounds, spanning the fields of medicine, agriculture, and industry. Professionals in the fields of microbiology, marine biology, pharmaceutical sciences, and drug development will gain valuable insights into the use of marine organisms as a source of antimicrobial agents. Audience Medicinal chemists, professional researchers and scholars in microbiology, marine biology and related fields in life sciences.

Author : Arumugam Veera Ravi
Publisher : Unknown
Page : 0 pages
File Size : 53,7 Mb
Release : 2023-10-02
Category : Science
ISBN : 9815080164

Get Book

Recent Advances in the Application of Marine Natural Products as Antimicrobial Agents by Arumugam Veera Ravi Pdf

Author : David H. Attaway,Oskar R. Zaborsky
Publisher : Springer Science & Business Media
Page : 532 pages
File Size : 42,8 Mb
Release : 1993-03-31
Category : Science
ISBN : 0306441748

Get Book

Pharmaceutical and Bioactive Natural Products by David H. Attaway,Oskar R. Zaborsky Pdf

Biotechnology may be defined as the application of scientific and engineering principles to the processing of materials by biological agents to provide goods and services (Bullet al. , 1982, p. 21) or as any technique that uses living organisms (or parts of organisms) to make or modify products, to improve plants or animals, or to develop microorganisms for specific use (OTC, 1988). In line with these broad definitions we can consider marine biotechnology as the use of marine organisms or their constituents for useful purposes in a controlled fashion. This series will explore a range of scientific advances in support of marine biotechnology. It will provide information on advances in three categories: (1) basic knowledge, (2) ap plied research and development, and (3) commercial and institutional issues. We hope the presentation of the topics will generate interest and interaction among readers in the academic world, government, and industry. This first volume examines chemical and biological properties of some natural products that are useful or potentially useful in research and in the chemical and pharmaceutical industries. One chapter describes a system for producing such substances on a large scale. Biotechnology incorporates molecular biology in order to go beyond tradi tional biochemical technology such as the production of antibiotic drugs from bacterial cultures in bioreactors. Development of the technology for production of antibiotics in this way resulted from fundamental advances in chemistry, phar macology, microbiology, and biochemical engineering.

Author : Milton Fingerman,R Nagabhushanam
Publisher : CRC Press
Page : 280 pages
File Size : 48,7 Mb
Release : 2002
Category : Science
ISBN : UCSD:31822031423106

Get Book

Recent Advances in Marine Biotechnology, Vol. 6 by Milton Fingerman,R Nagabhushanam Pdf

The marine environment has been, and continues to be, a fruitful source of novel chemical compounds that are not found in terrestrial and freshwater organisms. Many of these substances show potential biomedical applications, which could lead to development of new pharmaceutical products. Research on the utilization of natural products from marine organisms is growing by leaps and bounds; one important reason why being that, investigators, through new diving technologies, are becoming able to explore at greater depths. Studies of these marine natural products include investigations of neuronal membrane-active toxins, ion channel blockers, antitumor and antiviral agents, and anti-inflammatory molecules. This volume is the sixth in the ongoing series.

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on New Directions in the Study of Antimicrobial Therapeutics: Immunomodulation,Committee on New Directions in the Study of Antimicrobial Therapeutics: New Classes of Antimicrobials
Publisher : National Academies Press
Page : 102 pages
File Size : 49,6 Mb
Release : 2006-01-03
Category : Medical
ISBN : 9780309180689

Get Book

Treating Infectious Diseases in a Microbial World by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on New Directions in the Study of Antimicrobial Therapeutics: Immunomodulation,Committee on New Directions in the Study of Antimicrobial Therapeutics: New Classes of Antimicrobials Pdf

Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.

Author : Hiromasa Kiyota
Publisher : Springer
Page : 0 pages
File Size : 42,8 Mb
Release : 2010-11-11
Category : Science
ISBN : 3642070280

Get Book

Marine Natural Products by Hiromasa Kiyota Pdf

Author : Stephane La Barre,Stephen S. Bates
Publisher : John Wiley & Sons
Page : 984 pages
File Size : 50,5 Mb
Release : 2018-09-06
Category : Science
ISBN : 9783527801725

Get Book

Blue Biotechnology by Stephane La Barre,Stephen S. Bates Pdf

With its integral treatment of ecosystem and resource management, this is the only overview of the field to address current thinking and future trends. All contributions have been written with the novice in mind, explaining the basics and highlighting recent developments and achievements. Unmatched in scope, this two-volume reference covers both traditional and well-established areas of marine biotechnology, such as biomass production, alongside such novel ones as biofuels, biological protection of structures and bioinspired materials. In so doing, it ties together information usually only found in widely dispersed sources to assemble a grand unified view of the current state of and prospects for this multi-faceted discipline. The combination of the breadth of topics and the focus on modern ideas make this introductory book especially suitable for teaching purposes and for guiding newcomers to the many possibilities offered by this booming field.

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Ocean Studies Board,Committee on Marine Biotechnology: Biomedical Applications of Marine Natural Products
Publisher : National Academies Press
Page : 130 pages
File Size : 49,8 Mb
Release : 2002-05-29
Category : Science
ISBN : 9780309169714

Get Book

Marine Biotechnology in the Twenty-First Century by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Ocean Studies Board,Committee on Marine Biotechnology: Biomedical Applications of Marine Natural Products Pdf

Dramatic developments in understanding the fundamental underpinnings of life have provided exciting opportunities to make marine bioproducts an important part of the U.S. economy. Several marine based pharmaceuticals are under active commercial development, ecosystem health is high on the public's list of concerns, and aquaculture is providing an ever greater proportion of the seafood on our tables. Nevertheless, marine biotechnology has not yet caught the public's, or investor's, attention. Two workshops, held in October 1999 and November 2001 at the National Academies, were successful in highlighting new developments and opportunities in environmental and biomedical applications of marine biotechnology, and also in identifying factors that are impeding commercial exploitation of these products. This report includes a synthesis of the 2001 sessions addressing drug discovery and development, applications of genomics and proteomics to marine biotechnology, biomaterials and bioengineering, and public policy and essays contributed by the workshop speakers.

Author : Emiliano Manzo
Publisher : Unknown
Page : 148 pages
File Size : 44,8 Mb
Release : 2021-11-04
Category : Electronic
ISBN : 3036517685

Get Book

Synthesis of Marine Natural Products and Molecules Inspired by Marine Substances by Emiliano Manzo Pdf

Marine natural products are characterized by high chemical diversity, biochemical specificity, and other molecular properties that make them favorable as lead structures for drug discovery. In this field, one of the main problems is often the reduced natural availability of isolated substances, which can complicate both the structural characterization and possible future developments. For these reasons, the study of bioactive marine metabolites should rely on the development of chemical synthesis and synthetic strategies aimed at the preparation of pure compounds and analogs both for structural confirmation and/or for the large-scale preparation necessary for future applications. Moreover, natural products can be a crucial starting point for the preparation of molecules structurally inspired by the latter, opening the path to new classes of biologically active compounds with pharmacological potential. This book collects original research articles regarding synthetic strategies for secondary marine metabolites and/or analogs that favor applications of these molecules and/or solve structural challenges common in the field of natural substances.

Author : Atta-ur- Rahman,Shazia Anjum,Hesham El-Seedi
Publisher : Bentham Science Publishers
Page : 253 pages
File Size : 53,9 Mb
Release : 2018-03-03
Category : Medical
ISBN : 9781681082134

Get Book

Natural Products in Clinical Trials by Atta-ur- Rahman,Shazia Anjum,Hesham El-Seedi Pdf

Natural products continue to play a key role in drug development. A recent analysis of the drug market in the developed world revealed that 40% of total clinically approved drugs were either unmodified natural products or their semi-synthetic derivatives. This book series focuses on reviews of exciting new bioactive natural products that have huge potential as drugs. It highlights the everlasting importance of natural products in our lives. Each volume brings reviews contributed by eminent scientists in the field. The first volume covers the following topics: - bioactive compounds from marine invertebrates - natural product derived drugs for immunological and inflammatory diseases - clinical trials of curcumin, camptothecin, astaxanthin, and biochanin - antibacterial and antifungal drugs from natural sources - natural products as anti-HIV medicines.

Author : Dewan S. Bhakuni,D.S. Rawat
Publisher : Springer Science & Business Media
Page : 397 pages
File Size : 43,9 Mb
Release : 2006-06-30
Category : Science
ISBN : 9781402034848

Get Book

Bioactive Marine Natural Products by Dewan S. Bhakuni,D.S. Rawat Pdf

Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R and D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.

Author : Jean-Michel Mérillon,Céline Riviere
Publisher : Springer
Page : 337 pages
File Size : 47,6 Mb
Release : 2018-02-08
Category : Science
ISBN : 9783319670454

Get Book

Natural Antimicrobial Agents by Jean-Michel Mérillon,Céline Riviere Pdf

Documenting the latest research in the field of different pathogenic organisms, this book presents the current scenario about promising antimicrobials in the following areas: Part I. Plants as source of antibacterials, Part II. Naturally occurring antifungal natural products, Part III. Antiparasitic natural products, Part IV. Antiviral natural products. Renowned scientists from the globe have been selected as authors to contribute chapters. Use of plants for various ailments is as old as human civilization and continuous efforts are being made to improve medicinal plants or to product their bioactive secondary metabolites in high amounts through various technologies. About 200,000 natural products of plant origin are known and many more are being identified from higher plants and micro-organisms. Some plants based drugs are used since centuries and there is no alternative medicine for many such drugs as cardiac glycosides. Drug discovery from medicinal plants or marine micro-organisms continues to provide an important source of new drug leads. Research on new antibacterials represents a real and timely challenge of this century, particularly for the treatment of infections caused by clinical isolates that show multidrug resistance. The main microorganisms involved in the resistance process have been identified and given the acronym ESKAPE for Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanii, Pseudomonas aeruginosa and Enterobacteriaceae. Multidrug resistant Mycobacterium tuberculosis including highly drug-resistant strains (XDR-TB) has also emerged as one of the most important clinical challenges of this century. Plants of diverse taxa and marine micro-organisms are rich source of these antimicrobials. An attempt has been made to compile the recent information about natural sources of antibacterials and their sustainable utilization. Increased panic of these pathogens warrants a growing demand for research to undertake the threat of multidrug resistance. The search for new antifungal, antiparasitic and antiviral natural products is far from devoid of interest. According to the WHO report in 2013, malaria still represents some 207 million cases worldwide and more than 3 billion of people are still exposed to this risk. Similarly, about 350 million people are considered at risk of contracting leishmaniasis. The fight against some viruses also requires that the research on natural products continue. For example, even if an antiretroviral with direct action was recently approved in Europe in 2013, its high cost does not allow to offer it to an exposed population in countries where the cost of drugs remains a problem for a large part of the population. These books are useful to researchers and students in microbiology, biotechnology, pharmacology, chemistry and biology as well as medical professionals.

Author : Thomas Schwaha
Publisher : Walter de Gruyter GmbH & Co KG
Page : 458 pages
File Size : 53,9 Mb
Release : 2020-11-23
Category : Nature
ISBN : 9783110586312

Get Book

Phylum Bryozoa by Thomas Schwaha Pdf

With an account of over 6.000 recent and 15.000 fossil species, phylum Bryozoa represents a quite large and important phylum of colonial filter feeders. This volume of the series Handbook of Zoology contains new findings on phylogeny, morphology and evolution that have significantly improved our knowledge and understanding of this phylum. It is a comprehensive book that will be a standard for many specialists but also newcomers to the field of bryozoology.

Author : Ernesto Fattorusso,William H. Gerwick,Orazio Taglialatela-Scafati
Publisher : Springer
Page : 0 pages
File Size : 49,9 Mb
Release : 2012-04-21
Category : Science
ISBN : 9048138337

Get Book

Handbook of Marine Natural Products by Ernesto Fattorusso,William H. Gerwick,Orazio Taglialatela-Scafati Pdf

"Handbook of Marine Natural Products" takes a fresh approach to describing the major themes of research in this rapidly developing field. This two volume reference work begins with a section that provides a taxonomic survey of the secondary metabolites of diverse marine life including microbes, algae, and invertebrates. This is followed by a demonstration of the techniques and strategies employed in modern structure elucidation of complex natural products. The natural roles of marine natural products are then explored in a series of focused chapters which include the topics of symbiosis, anti-predation and antifouling, chemical interactions, and defence against UV stress. Various routes which facilitate the understanding of marine natural product biosynthesis are subsequently explained and these are followed by an extensive set of chapters on the biomedical potential of marine natural products. The latter portion of this section considers the technologies and scientific disciplines necessary for advancing bioactive marine natural product lead compounds into actual pharmaceuticals. The reference work finishes with a selection of chapters describing marine toxins and their impact on public health and seafood resources. Final thoughts presented at the end of the second volume focus on the future of this field of investigation and discovery research. This publication is presented as a reference handbook and general concepts are emphasized and illustrated with numerous interesting examples, graphical information, and a comprehensive index. "Handbook of Marine Natural Products" introduces students who are at advanced undergraduate and entry graduate student levels to this fascinating multidisciplinary field. It is an ideal desk companion for courses focusing on this contemporary area.

Author : Stephen Hanessian
Publisher : John Wiley & Sons
Page : 652 pages
File Size : 46,6 Mb
Release : 2013-12-18
Category : Medical
ISBN : 9783527676552

Get Book

Natural Products in Medicinal Chemistry by Stephen Hanessian Pdf

The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters. Using well-documented studies over the past decade, this timely monograph demonstrates the current importance and future potential of natural products as starting points for the development of new drugs with improved properties over their progenitors. The examples are chosen so as to represent a wide range of natural products with therapeutic relevance among others, as anticancer agents, antimicrobials, antifungals, antisense nucleosides, antidiabetics, and analgesics. From the content: * Part I: Natural Products as Sources of Potential Drugs and Systematic Compound Collections * Part II: From Marketed Drugs to Designed Analogs and Clinical Candidates * Part III: Natural Products as an Incentive for Enabling Technologies * Part IV: Natural Products as Pharmacological Tools * Part V: Nature: The Provider, the Enticer, and the Healer