Root Development Towards Understanding Regulatory Networks And Complex Interactions Between Cell Populations
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Root Development: Towards Understanding Regulatory Networks and Complex Interactions Between Cell Populations by Svetlana Shishkova,Ling Huang,Ramiro Esteban Rodriguez,Daniela Ristova,Raffaele Dello Ioio Pdf
The understanding of biological complexity has been greatly facilitated by cross-disciplinary, holistic approaches that allow insights into the function and regulation of biological processes that cannot be captured by dissecting them into their individual components. In addition, the development of novel tools has dramatically increased our ability to interrogate information at the nucleic acid, protein and metabolite level. The integration and interpretation of disparate data sets, however, still remain a major challenge in systems biology. Roots provide an excellent model for studying physiological, developmental, and metabolic processes. The availability of genetic resources, along with sequenced genomes has allowed important discoveries in root biochemistry, development and function. Roots are transparent, allowing optical investigation of gene activity in individual cells and experimental manipulation. In addition, the predictable fate of cells emerging from the root meristem and the continuous development of roots throughout the life of the plant, which permits simultaneous observation of different developmental stages, provide ideal premises for the analysis of growth and differentiation. Moreover, a genetically fixed cellular organization allows for studying the utilization of positional information and other non-cell-autonomous phenomena, which are of utmost importance in plant development. Although their ontogeny is largely invariant under standardized experimental conditions, roots possess an extraordinary capacity to respond to a plethora of environmental signals, resulting in distinct phenotypic readouts. This high phenotypic plasticity allows research into acclimative and adaptive strategies, the understanding of which is crucial for germplasm enhancement and crop improvement. With the aim of providing a current snapshot on the function and development of roots at the systems level, this Research Topic collated original research articles, methods articles, reviews, mini reviews and perspective, opinion and hypotheses articles that communicate breakthroughs in root biology, as well as recent advances in research technologies and data analysis.
Plant Systems Biology by Sacha Baginsky,Alisdair R. Fernie Pdf
This volume aims to provide a timely view of the state-of-the-art in systems biology. The editors take the opportunity to define systems biology as they and the contributing authors see it, and this will lay the groundwork for future studies. The volume is well-suited to both students and researchers interested in the methods of systems biology. Although the focus is on plant systems biology, the proposed material could be suitably applied to any organism.
The Radish Genome by Takeshi Nishio,Hiroyasu Kitashiba Pdf
This book summarizes the latest information and the status quo of radish genome studies to stimulate innovations and improvements in breeding techniques and to promote further advances in the field. Radish (Raphanus sativus) is a member of the Brassicaceae family and is cultivated worldwide. Its varieties have been diversified in terms of size, shape, and the color of their roots and bio-components. Thanks to the development of high-throughput molecular techniques using next generation sequencers, complete genomes of cultivated and wild radish plants have been sequenced and published with annotations of predicted genes and single nucleotide polymorphism (SNP) information between radish cultivars and accessions. These, together with the construction of a high-density genetic map of radish and profiling of expression sequences in radish organs, have accelerated genetic studies, such as the identification of genes or loci associated with root development, pungent components, and plant disease resistance. Providing an overview of these advances, this book is a valuable resource for scientists involved in plant genetic research and crop breeding.
Transcriptional Control of Neural Crest Development by Brian Nelms,Patricia Labosky Pdf
The neural crest is a remarkable embryonic population of cells found only in vertebrates and has the potential to give rise to many different cell types contributing throughout the body. These derivatives range from the mesenchymal bone and cartilage comprising the facial skeleton, to neuronal derivatives of the peripheral sensory and autonomic nervous systems, to melanocytes throughout the body, and to smooth muscle of the great arteries of the heart. For these cells to correctly progress from an unspecifi ed, nonmigratory population to a wide array of dynamic, differentiated cell types—some of which retain stem cell characteristics presumably to replenish these derivatives—requires a complex network of molecular switches to control the gene programs giving these cells their defi ning structural, enzymatic, migratory, and signaling capacities. This review will bring together current knowledge of neural crest-specifi c transcription factors governing these progressions throughout the course of development. A more thorough understanding of the mechanisms of transcriptional control in differentiation will aid in strategies designed to push undifferentiated cells toward a particular lineage, and unraveling these processes will help toward reprogramming cells from a differentiated to a more naive state. Table of Contents: Introduction / AP Genes / bHLH Genes / ETS Genes / Fox Genes / Homeobox Genes / Hox Genes / Lim Genes / Pax Genes / POU Domain Genes / RAR/RXR Genes / Smad Genes / Sox Genes / Zinc Finger Genes / Other Miscellaneous Genes / References / Author Biographies
Handbook of Systems Biology by Marian Walhout,Marc Vidal,Job Dekker Pdf
This book provides an entry point into Systems Biology for researchers in genetics, molecular biology, cell biology, microbiology and biomedical science to understand the key concepts to expanding their work. Chapters organized around broader themes of Organelles and Organisms, Systems Properties of Biological Processes, Cellular Networks, and Systems Biology and Disease discuss the development of concepts, the current applications, and the future prospects. Emphasis is placed on concepts and insights into the multi-disciplinary nature of the field as well as the importance of systems biology in human biological research. Technology, being an extremely important aspect of scientific progress overall, and in the creation of new fields in particular, is discussed in 'boxes' within each chapter to relate to appropriate topics. 2013 Honorable Mention for Single Volume Reference in Science from the Association of American Publishers' PROSE Awards Emphasizes the interdisciplinary nature of systems biology with contributions from leaders in a variety of disciplines Includes the latest research developments in human and animal models to assist with translational research Presents biological and computational aspects of the science side-by-side to facilitate collaboration between computational and biological researchers
Contemporary Endodontics for Children and Adolescents by Anna B. Fuks,Moti Moskovitz,Nili Tickotsky Pdf
This book equips dental practitioners with all the information required in order to ensure successful endodontic treatment of children and adolescents. It describes pulp therapy from a holistic approach that highlights new developments in the field. Readers will find updates on the formation, structure and function of the dental pulp revealed by the latest single-cell technologies, and discussions on carious lesions and their impact on the pulp. The book examines clinical considerations in the decision to perform pulp treatment and emphasizes the need to integrate pupal diagnostics with patient-dependent factors such as behavior management and pulpal pain mechanisms. The second part of the book includes comprehensive descriptions of current treatments for each type of caries-inflicted tooth damage, from selective caries removal through direct pulp capping, pulpotomy, pulpectomy and root canal therapy for primary dentition to direct pulp capping and endodontic treatment of young permanent teeth. Traditional and new pulp-treatment materials are described as are the techniques and materials used to restore both primary and young permanent teeth. The book summarizes innovative biological approaches for pulp regeneration such as the use of stem cells. It is a must have for dental students, endodontists, pediatric dentists and general dentists with an interest in the subject.
Auxin and Its Role in Plant Development by Eva Zažímalová,Jan Petrášek,Eva Benková Pdf
Auxin is an important signaling compound in plants and vital for plant development and growth. The present book, Auxin and its Role in Plant Development, provides the reader with detailed and comprehensive insight into the functioning of the molecule on the whole and specifically in plant development. In the first part, the functioning, metabolism and signaling pathways of auxin in plants are explained, the second part depicts the specific role of auxin in plant development and the third part describes the interaction and functioning of the signaling compound upon stimuli of the environment. Each chapter is written by international experts in the respective field and designed for scientists and researchers in plant biology, plant development and cell biology to summarize the recent progress in understanding the role of auxin and suggest future perspectives for auxin research.
Environmental Microbiology: Fundamentals and Applications by Jean-Claude Bertrand,Pierre Caumette,Philippe Lebaron,Robert Matheron,Philippe Normand,Télesphore Sime-Ngando Pdf
This book is a treatise on microbial ecology that covers traditional and cutting-edge issues in the ecology of microbes in the biosphere. It emphasizes on study tools, microbial taxonomy and the fundamentals of microbial activities and interactions within their communities and environment as well as on the related food web dynamics and biogeochemical cycling. The work exceeds the traditional domain of microbial ecology by revisiting the evolution of cellular prokaryotes and eukaryotes and stressing the general principles of ecology. The overview of the topics, authored by more than 80 specialists, is one of the broadest in the field of environmental microbiology. The overview of the topics, authored by more than 80 specialists, is one of the broadest in the field of environmental microbiology.
This title includes a number of Open Access chapters. This book covers a wide scope of biological approaches to such biological phenomena as cell division, motility, collective cell behavior, multicellular structures, morphogenesis, and tumor development. Over the past two decades, biologists have generated large sets of experimental data and discovered a lot of facts that need explanation. This biological boom attracts physicists who believe they can help to develop a theoretical framework in biology and explain complete biological phenomena using basic principles. This is the first book to present recent advances in biophysical studies of the different aspects of cell life. This book presents recent advances in biophysical studies of living cells and gives the impression that a combination of quantitative live cell observations, detailed biochemical and biophysical data, and mathematical modeling are capable to answer many important biological questions and to achieve a more complete understanding of such complex phenomena.
Bacterial Metabolites in Sustainable Agroecosystem by Dinesh K. Maheshwari Pdf
There has been a resurgence of interest in environmental friendly, sustainable and organic cultural practices that warrants high yield and quality in agricultural crops. To enhance sustainable agricultural production and alleviate food scarcity, spoor of majority of microorganisms, especially plant growth and health promoting bacteria of eminent characteristics that allow them for exploitation in agro-ecosystem. Plant growth promoting rhizobacteria are the soil bacteria inhabiting around/on the root surface and are directly or indirectly involved in promoting plant growth and development via production and secretion of various regulatory chemicals in the vicinity of rhizosphere. Among various beneficial bacteria mediated mechanisms include direct production of phytohormones and biosurfactants experiencing quest of research and concept up gradation that can built emerging paradigm (agriculture model). Research on bacteria-mediated phytohormones is crucially important, provides key understanding of the plant growth and development. Various genera including PGPR group of bacteria are potential source of plant growth regulators. Application of such organism allow plants to survive under abiotic and biotic stress conditions besides govern phytohormone mediated immune response and manage to regulate hormones. Such group of bacteria also produce another important metabolite i.e. biosurfacatants which are involved in many important functions to bacteria itself as we ll as for the plants and their ecosystem. Biosurfactants may alter nutrient availability, endogenous metabolites such as antibiotics production, root colonization imparting protection from phytopathogens besides eradicating soil contaminants and other pollutants. The role and activities of surfactants produced by bacteria are multifarious in nature. Thus, bacterial phytohormones and biosurfactants are identified as effector molecules in plant- microbe interactions, in pathogenesis and phyto-stimulation which can either be beneficial for the bacteria itself or for the crops. This book highlights current applications and research on bacterial hormones and surfactants to provide a timely overview. The chapters have been contributed by subject experts from around the world and include topics of varied importance which include phytohormones production by rhizospheric and endophytic bacteria, their role in rhizosphere competence, plant growth regulation, bioremediation, biosurfactants as antibiofilm agents and other aspects. This major new work represents a valuable source of information to all those scientists interested in microbial technology with respect to the microbial innovative products and applications towards sustainable agroecosystem.
