Sex Chromosomes And Sex Determination In Vertebrates

Author : Alberto J. Solari
Publisher : CRC Press
Page : 340 pages
File Size : 40,9 Mb
Release : 1993-10-22
Category : Nature
ISBN : 0849345715

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Sex Chromosomes and Sex Determination in Vertebrates by Alberto J. Solari Pdf

The cloning of the SRY gene and the attainment of XX mice transgenic for the Sry gene opened a new era in research on sex determination. This book surveys current knowledge of sex chromosomes and sex determination in all vertebrate classes, relying on the restriction of genetic recombination in sex chromosomes as the unifying concept of this subject. The book's interdisciplinary approach integrates contributions from the fields of cytogenetics, molecular biology, developmental biology, and evolutionary genetics. A detailed treatment of the meiotic behavior of sex chromosomes is featured, and the entire text is supplemented by numerous schemes, drawings, and electron micrographs. The book will be valuable to general cytogeneticists, vertebrate zoologists, and veterinarian and medical practitioners interested in the foundations of sex determination and the current knowledge of sex chromosomes. It will also interest students in advanced undergraduate and graduate courses in these areas.

Author : Gerd Scherer,Michael Schmid
Publisher : Birkhäuser
Page : 210 pages
File Size : 51,7 Mb
Release : 2013-04-17
Category : Science
ISBN : 9783034877817

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Genes and Mechanisms in Vertebrate Sex Determination by Gerd Scherer,Michael Schmid Pdf

Following an opening chapter by the late Susumu Ohno on paralogues of sex-determining genes, the five best-studied genes essential for early mammalian gonadal development are portrayed in detail: SF-1 and WT1 and their roles in early events in gonadal development, SRY and SOX9 in testis determination, and the anti-testis gene DAX-1. Subsequent chapters look at the roles of these genes in sex determination in marsupial mammals, birds, reptiles, amphibians and fish, and review the different sex-determining mechanisms, genetic and environmental, that operate in these different vertebrate classes. Two insights emerge: one, that the same basic set of genes appears to operate during early gonadal development in all vertebrates, despite the differences in mechanisms; the other, that sex determination in vertebrates results from a complex network of regulatory interactions and not from a simple hierarchical cascade of gene actions.

Author : Anonim
Publisher : Academic Press
Page : 394 pages
File Size : 45,8 Mb
Release : 2019-04-16
Category : Science
ISBN : 9780128115046

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Sex Determination in Vertebrates by Anonim Pdf

Sex Determination, Volume 134, the latest release in the Current Topics in Developmental Biology series, contains current reviews in the field of vertebrate sex determination. It covers molecular pathways of sex determination in genetic and environmental species and encompasses both sex determination of somatic lineages and commitment of germ cells to male or female fate. Chapters in this new release cover, amongst other topics, Mapping the Sox9 Enhancer Elements, Epigenetic Regulation of Sex Determination, Evolution and Management of Sex Chromosomes, Regulation of Germ Cell Sex Identity in Medaka, Control of Sex Determination in Zebrafish, Sexually Dimorphic Germ Cell Identity in Mammals, and more. Contains reviews written by leading experts in each field Includes informative figures that illustrate principle points that are useful for teaching Written in a style that is clear and simple

Author : Nobuo Takagi
Publisher : S. Karger AG (Switzerland)
Page : 352 pages
File Size : 50,8 Mb
Release : 2003
Category : Medical
ISBN : 3805576374

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Vertebrate Sex Chromosomes by Nobuo Takagi Pdf

During the last two decades of the 20th century, the study of chromosomes was enormously stimulated by the availability of various biological resources, valuable databases and new genetic and molecular biological techniques including PCR and fluorescent in situ hybridization. The simultaneous development of new and effective systems for targeting genes and gene transfer led to astonishing advances also in the study of vertebrate sex chromosomes. We now have considerable insight into their evolution, the dosage compensation mechanisms in mammals that involve chromosome-wide chromatin remodeling triggered by noncoding Xist RNA, and the unique properties of the human X chromosome which comprises many genes important for sex determination and reproduction. This thematic issue of Cytogenetic and Genome Research presents an excellent and highly authoritative compilation of current research findings related to vertebrate sex chromosomes. The contributions - all prepared by experts in the field - reflect both the technical advances and the enormous gain in knowledge achieved in recent years. Many of these papers also provide important historical perspectives while some contain insightful personal views of the authors. This special volume therefore represents a stimulating and critical state-of-the-art source of information for investigators and students in this fascinating field.

Author : Nicole Valenzuela,Valentine A. Lance
Publisher : Smithsonian Institution Scholarly Press
Page : 204 pages
File Size : 49,8 Mb
Release : 2004
Category : Science
ISBN : UCSD:31822034180331

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Temperature-Dependent Sex Determination in Vertebrates by Nicole Valenzuela,Valentine A. Lance Pdf

Edited by the world's foremost authorities on the subject, with essays by leading scholars in the field, this work shows how the sex of reptiles and many fish is determined not by the chromosomes they inherit but by the temperature at which incubation takes place.

Author : Leo W. Beukeboom,Nicolas Perrin
Publisher : Oxford University Press, USA
Page : 243 pages
File Size : 48,9 Mb
Release : 2014
Category : Science
ISBN : 9780199657148

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The Evolution of Sex Determination by Leo W. Beukeboom,Nicolas Perrin Pdf

temperature) or social variables (e.g.

Author : Ettore Olmo
Publisher : S. Karger AG (Switzerland)
Page : 152 pages
File Size : 49,9 Mb
Release : 2010
Category : Genetic sex determination
ISBN : STANFORD:36105215525515

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Sex Determination and Differentiation in Reptiles by Ettore Olmo Pdf

Reptiles are a fascinating group for the study of sexual development because they exhibit a wide range of sex-determining mechanisms, from strict genetic sex determination (GSD) to strict thermal sex determination (TSD) and intermediate systems of GSD that are to various degrees overridden by environmental effects . This thematic issue presents the latest data on different aspects of sex determination in reptiles. Following an evolutionary perspective on why reptiles might be predisposed to evolve TSD, the papers in this issue explore in detail the different genetic and molecular mechanisms of sex determination and differentiation. They consider recent findings such as the discovery of new genes differentially expressed at male and female sex-determining temperatures, a new model of the role of aromatase, and the contribution of heat-shock proteins to TSD in the American alligator. Further studies examine the role played by sex allocation, the advantage of viviparity, and the effects of anthropogenic climate change on the sex ratio in TSD reptile populations. Providing a valuable overview for both students and researchers, this publication is essential reading for developmental and reproductive biologists, herpetologists, comparative endocrinologists, evolutionary biologists and geneticists.

Author : Ken Reed,Jennifer A. Marshall Graves
Publisher : Unknown
Page : 410 pages
File Size : 40,6 Mb
Release : 1993
Category : Mammals
ISBN : OCLC:1288479825

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Sex Chromosomes and Sex-determining Genes by Ken Reed,Jennifer A. Marshall Graves Pdf

Author : Derek J. Chadwick,Jamie A. Goode
Publisher : John Wiley & Sons
Page : 286 pages
File Size : 41,5 Mb
Release : 2002-04-26
Category : Science
ISBN : 0470843462

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The Genetics and Biology of Sex Determination by Derek J. Chadwick,Jamie A. Goode Pdf

Nature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be explored at the cellular and molecular levels. A major landmark was the discovery in 1990 of the SRY gene and the subsequent demonstration of its key role in triggering male sex determination in transgenic mice. This book reviews and discusses our current understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. It features comparisons with other modes of sex determination, consideration of the biology of sexual development and discussion of the evolution of sex-determining mechanisms. By bringing together an international and interdisciplinary group of experts who study many different aspects of the problem, the book highlights much new and exciting work in this area and serves to identify and stimulate promising new research directions.

Author : Anonim
Publisher : Unknown
Page : 111 pages
File Size : 52,5 Mb
Release : 1999
Category : Electronic
ISBN : OCLC:437106340

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Genes and Mechanisms in Vertebrate Sex Determination by Anonim Pdf

Author : Aleksandr F. Smirnov,A. V. Trukhina
Publisher : Scientific Research Publishing, Inc. USA
Page : 118 pages
File Size : 47,9 Mb
Release : 2024-05-19
Category : Science
ISBN : 9781618963901

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Molecular-Genetic Mechanisms of Sex Determination in Animals by Aleksandr F. Smirnov,A. V. Trukhina Pdf

Gender (sex) is a set of morphological and physiological characteristics of the organism underlying sexual reproduction, the essence of which is reduced to fertilization, i.e. the fusion of male and female gametes (gametes) zygote, which develops into a new organism.Sexual reproduction of a species is considered as one of the mechanisms of its homeostasis. Thanks to this mechanism, numerous species have an evolutionary advantage. In the book, two authors will discuss the types of genetic sex determination and differentiation, mostly in multicellular animal organisms. Sex determination is both genetic and environmental process, the sex of an individual being established through an alternative physiological solution. There are two main postulated mechanisms of sex determination: genetic (GSD, Genetical Sex Determination) and environmental (ESD, Environmental Sex Determination).

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
Publisher : National Academies Press
Page : 288 pages
File Size : 49,7 Mb
Release : 2001-07-02
Category : Medical
ISBN : 0309132975

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Exploring the Biological Contributions to Human Health by Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences Pdf

It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Author : Elof Axel Carlson
Publisher : Indiana University Press
Page : 257 pages
File Size : 54,8 Mb
Release : 2013-02-12
Category : Psychology
ISBN : 9780253006455

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The 7 Sexes by Elof Axel Carlson Pdf

Few of us know much about the biology of sex determination, but what could be more interesting than to discover how we are shaped into males and females? In this book, Elof Carlson tells the incredible story of the difficult quest to understand how the body forms girls and boys. Carlson's history takes us from antiquity to the present day to detail how each component of human reproduction and sexuality was identified and studied, how this knowledge enlarged our understanding of sex determination, and how it was employed to interpret such little understood aspects of human biology as the origin of intersex births.

Author : T. J. Pandian
Publisher : CRC Press
Page : 294 pages
File Size : 52,8 Mb
Release : 2011-09-02
Category : Science
ISBN : 9781439879191

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Sex Determination in Fish by T. J. Pandian Pdf

This book is the first to report that research in allogenics/xenogenics has conclusively shown that fishes have retained bisexual potency even after sexual maturity and spermiation. The XY genotype found in the unexpected female phenotypes sired by supermales (Y1Y2) and androgenic males (Y2Y2) points out the need to employ sex specific molecular ma

Author : Stephen S. Wachtel
Publisher : Academic Press
Page : 518 pages
File Size : 47,5 Mb
Release : 2014-07-23
Category : Science
ISBN : 9781483295589

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Molecular Genetics of Sex Determination by Stephen S. Wachtel Pdf

In this era of accelerated discovery and prolific output, Molecular Genetics of Sex Determination keeps readers abreast of this fields fast-moving biology. Its chapters were completed by experts in eacharea only months before publication. The text is organized into two parts. First, it reviews the basic biology of sex determination and summarizes ground-breaking work in mouse, marsupial, and Drosophila systems. Second, it covers current human genetics, clinical studies, and the syndromes of abnormal sex differentiation. With chapters by preeminent reproductive biologists, this is a capital work. Ohno's law is described by Ohno; the Lyon hypothesis, by Lyon; Sinclair tells how he cloned the testis-determining gene; and so on. Molecular Genetics of Sex Determination is authoritative, comprehensive, and current. It is prime reading for geneticists, developmental biologists, graduate students in these and related fields, clinical researchers, physicians, and medical students. Reviews the genetics of sex determination in 19 up-to-date chapters Features research on sex chromosomes and sex-determining genes Includes abnormalities of sex determination and clinical genetics Written by scientists who pioneered work in this field