Soft Tissue Sarcomas New Developments In The Multidisciplinary Approach To Treatment

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Soft Tissue Sarcomas: New Developments in the Multidisciplinary Approach to Treatment

H.M. Pinedo,J. Verweij,H.D. Suit
Soft Tissue Sarcomas New Developments in the Multidisciplinary Approach to Treatment Book PDF

Author : H.M. Pinedo,J. Verweij,H.D. Suit
Publisher : Springer Science & Business Media
Page : 181 pages
File Size : 51,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461538967

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Soft Tissue Sarcomas: New Developments in the Multidisciplinary Approach to Treatment by H.M. Pinedo,J. Verweij,H.D. Suit Pdf

Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative, but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfor tunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, which is revised frequently to keep the coverage up to date, and which is easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions, such as lung can cer, genitourinary cancer, pediatric oncology, etc.; and second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diag nosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Treatment of Soft Tissue Sarcomas

H.M. Pinedo,J. Verweij
Treatment of Soft Tissue Sarcomas Book PDF

Author : H.M. Pinedo,J. Verweij
Publisher : Springer Science & Business Media
Page : 143 pages
File Size : 48,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461317579

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Treatment of Soft Tissue Sarcomas by H.M. Pinedo,J. Verweij Pdf

One of the major advances of the last decade concerning the treatment of patients with soft tissue sarcomas is that an increased number of patients are being discussed in multidisciplinary teams prior to the initial treatment. The present volume on soft tissue sarcomas in the series Cancer Treatment and Research reflects the multidisciplinary approach with a focus on recent developments. The availability of new histopathologic techniques has reduced the number of unclassified sarcomas and has furhter increased the importance of the histo pathologist in providing estimates of the prognosis of the patient as well as data for the planning of treatment strategy. Further data for this strategy will be provided by diagnostic imaging. In this field, the role of magnetic reson ance imaging has been further defined. Of utmost importance is the recent trend toward consensus in staging. The modification of the staging system of the American Joint Commission for Cancer Staging and End Results Report ing brings the possibility of a single staging system within reach in the next decade. As surgery still provides the only chance for cure, the importance of being the most sparing as possible is obvious. For this reason, radiotherapy has been applied with success. The introduction of relatively new radiation tech niques is therefore being observed with interest.

Multidisciplinary Treatment of Soft Tissue Sarcomas

J. Verweij,H.M. Pinedo,H.D. Suit
Multidisciplinary Treatment of Soft Tissue Sarcomas Book PDF

Author : J. Verweij,H.M. Pinedo,H.D. Suit
Publisher : Springer Science & Business Media
Page : 274 pages
File Size : 48,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461530824

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Multidisciplinary Treatment of Soft Tissue Sarcomas by J. Verweij,H.M. Pinedo,H.D. Suit Pdf

The previous volume of this series on soft tissue sarcomas highlighted the importance of the multidisciplinary approach to treatment, the focus of which is continued in the present edition. Proper diagnosis and staging remain the cornerstone of the treatment strategy. Sophisticated histopathology techniques and growing consensus on grading systems have further increased the importance of the histopathologist in providing estimates of the prognosis of the patient as well as providing data for the planning of treatment strategy. The use of cytogenetics is relatively new in this field. This might enable the distinction of subgroups in specific histological tumor types. Furthermore, molecular biological studies not only help to reveal inherited predispositions and details in oncogenesis in tumor development, but they may also provide additional predictive factors for tumor behavior. Further data on treatment strategy will be provided by diagnostic imaging, a field in which the role of magnetic resonance imaging is rapidly developing. As far as actual treatment is concerned, surgery still provides the major chance for cure. In view of the endeavor to be as sparing as possible, the addition of radiotherapy to surgery is of utmost importance. Usually radiotherapy is given after surgery, but the optimal sequence of the two modalities still needs to be defined. The combined use of surgery with radiotherapy and/or chemotherapy does have an impact on wound healing.

Sarcoma, a Multidisciplinary Approach to Treatment

Robert M. Henshaw
Sarcoma a Multidisciplinary Approach to Treatment Book PDF

Author : Robert M. Henshaw
Publisher : Unknown
Page : 128 pages
File Size : 54,7 Mb
Release : 2017
Category : Health care teams
ISBN : 331943120X

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Sarcoma, a Multidisciplinary Approach to Treatment by Robert M. Henshaw Pdf

The purpose of this book is to define and demonstrate how a multidisciplinary team can be organized, integrated, and utilized in the care of sarcoma patients. Real world experiences related by multiple sarcoma specialists working as members of a multidisciplinary team along with specific case examples highlighting sarcomas of bone and soft tissue in children and adults are presented in a framework geared toward practicing oncologists and surgeons in order to foster the creation and development of care teams for sarcoma patients. It is explained how a truly multidisciplinary approach, with "one stop shopping," offers better standardization and delivery of care, streamlines patient education, facilitates discussions and decision making, and provides comprehensive support throughout the treatment process. All aspects of treatment are covered, from first-line treatments for different tumor types through to salvage therapy and the development of novel investigational agents. This book will be of benefit to all members of the medical community who have a role to play in the care of these complex patients, including therapists, nurses, mid-level practitioners, primary care doctors, and subspecialists.

Soft Tissue Sarcomas: Present Achievements and Future Prospects

J. Verweij,H.M. Pinedo,H.D. Suit
Soft Tissue Sarcomas Present Achievements and Future Prospects Book PDF

Author : J. Verweij,H.M. Pinedo,H.D. Suit
Publisher : Springer Science & Business Media
Page : 336 pages
File Size : 50,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461561217

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Soft Tissue Sarcomas: Present Achievements and Future Prospects by J. Verweij,H.M. Pinedo,H.D. Suit Pdf

The previous volumes in this series on soft tissue sarcomas highlighted the importance of the multidisciplinary approach to treatment, and this focus is continued in the present volume. Proper diagnosis and staging remain the cornerstone of the treatment strategy. Sophisticated histopathology tech niques and growing consensus on grading systems have further increased the importance of the histopathologist in providing estimates of patient prognosis as well as in providing data for planning the treatment strategy. The use of cytogenetics in this field is rapidly increasing and might enable the distinction of subgroups in specific histological tumor types. Furthermore, molecular biological studies not only help reveal inherited predispositions and details in tumor oncogenesis, but they may also provide additional predictive factors for tumor behavior. Further data on treatment strategy will be provided by diag nostic imaging, and in this volume the value of PET imaging, a relatively new achievement, is highlighted. As far as the actual treatment is concerned, surgery still provides the major opportunity for cure. The addition of radiotherapy to surgery is of utmost importance in efforts to spare as much tissue as possible. The chapters on the planning of radiotherapy, brachytherapy, and the treatment of benign soft tissue lesions using radiotherapy are new contributions to this book. One of the potential late problems of radiotherapy is the occurrence of secondary soft tissue sarcomas, which is discussed in Chapter 10.

Treatment of Bone and Soft Tissue Sarcomas

Per-Ulf Tunn
Treatment of Bone and Soft Tissue Sarcomas Book PDF

Author : Per-Ulf Tunn
Publisher : Springer Science & Business Media
Page : 372 pages
File Size : 50,9 Mb
Release : 2008-12-28
Category : Medical
ISBN : 9783540779605

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Treatment of Bone and Soft Tissue Sarcomas by Per-Ulf Tunn Pdf

Bone and soft tissue sarcomas represent only about 2% of all malignancies; however, their treatment – with the goal of curing the patient while preserving the functionality of the affected body part – can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept.

Sarcoma

Peter F. M. Choong
Sarcoma Book PDF

Author : Peter F. M. Choong
Publisher : Springer Nature
Page : 345 pages
File Size : 47,7 Mb
Release : 2020-12-09
Category : Medical
ISBN : 9789811594144

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Sarcoma by Peter F. M. Choong Pdf

This book aims to compile an expert text on the multidisciplinary approach to treating sarcoma at a sarcoma centre. Separate chapters and sections highlight the specialist diagnostic and therapeutic approaches employed in treating bone and soft tissue sarcoma. This comprehensive book covers sarcoma and its management across specialties. It brings together the experience of the editor at a major centre for sarcoma management in Australia along with chapter contributions from various experts on the topic. The real-life, pragmatic approach is a distillation of the evidence and intends to make much of what is written translatable. This book serves as a reference for managing this tumour type and as an indispensable guide for daily use across the spectrum of providers.

Recent Advances in Clinical Trial Design and Analysis

Peter F. Thall
Recent Advances in Clinical Trial Design and Analysis Book PDF

Author : Peter F. Thall
Publisher : Springer Science & Business Media
Page : 263 pages
File Size : 50,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461520092

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Recent Advances in Clinical Trial Design and Analysis by Peter F. Thall Pdf

Clinical trials have two purposes -- to treat the patients in the trial, and to obtain information which increases our understanding of the disease and especially how patients respond to treatment. Statistical design provides a means to achieve both these aims, while statistical data analysis provides methods for extracting useful information from the trial data. Recent advances in statistical computing have enabled statisticians to implement very rapidly a broad array of methods which previously were either impractical or impossible. Biostatisticians are now able to provide much greater support to medical researchers working in both clinical and laboratory settings. As our collective toolkit of techniques for analyzing data has grown, it has become increasingly difficult for biostatisticians to keep up with all the developments in our own field. Recent Advances in Clinical Trial Design and Analysis brings together biostatisticians doing cutting-edge research and explains some of the more recent developments in biostatistics to clinicians and scientists who work in clinical trials.

Advances in Radiation Therapy

Bharat B. Mittal,James A. Purdy,K.K. Ang
Advances in Radiation Therapy Book PDF

Author : Bharat B. Mittal,James A. Purdy,K.K. Ang
Publisher : Springer Science & Business Media
Page : 308 pages
File Size : 47,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461557692

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Advances in Radiation Therapy by Bharat B. Mittal,James A. Purdy,K.K. Ang Pdf

Recent advances in radiation oncology have depended upon and are intertwined with subsequent scientific discoveries and the development of new techniques in the fields of radiation and molecular biology, physics, electrical engineering, surgery, and medical oncology. This volume describes how some of the recent discoveries in the radiological sciences have influenced the way radiation oncology is practised. As there are many advances in this field, the Editors have chosen to concentrate on selected topics in clinical radiotherapy, radiation physics and biology, and technical innovations that have had a major impact on radiation oncology in the past twenty years. It is hoped that the techniques described in this volume will increase tumor control and prolong patient survival and at the same time decrease radiation-induced side effects and complications.

Pediatric Bone and Soft Tissue Sarcomas

Alberto S. Pappo
Pediatric Bone and Soft Tissue Sarcomas Book PDF

Author : Alberto S. Pappo
Publisher : Springer Science & Business Media
Page : 247 pages
File Size : 43,6 Mb
Release : 2005-12-31
Category : Medical
ISBN : 9783540294474

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Pediatric Bone and Soft Tissue Sarcomas by Alberto S. Pappo Pdf

The field of pediatric bone and soft tissue sarcomas has experienced a gradual but surprising transformation. Fundamental discoveries in the molecular biology of disease, recent breakthroughs in diagnostic imaging, and revolutionary surgical techniques have created unprecedented synergies and a refreshing vision with which to approach the diagnosis and treatment of these pediatric tumors. This book highlights the paths leading to the emergence of such a new vision and presents salient concepts in epidemiology, novel tools in imaging and molecular biology, and principles of drug development as the scaffold to understanding the pathophysiology and treatment of pediatric sarcomas. The book is aimed at providing an up-to-date comprehensive reference text which articulates a multidisciplinary approach for the diagnosis and treatment of each of these often challenging diseases.

Advances in Allogeneic Hematopoietic Stem Cell Transplantation

Richard K. Burt,Mary M. Brush
Advances in Allogeneic Hematopoietic Stem Cell Transplantation Book PDF

Author : Richard K. Burt,Mary M. Brush
Publisher : Springer
Page : 419 pages
File Size : 45,7 Mb
Release : 2012-11-28
Category : Medical
ISBN : 9781461549871

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Advances in Allogeneic Hematopoietic Stem Cell Transplantation by Richard K. Burt,Mary M. Brush Pdf

The field of hematopoietic stem cell transplantation is rapidly evolving. Realization that hematopoietic stem cells give rise to the immune compartment has resulted in clinical trials of hematopoietic stem cell transplantation for patients with autoimmune diseases. Allogeneic hematopoietic transplants are a form of adoptive immunotherapy resulting in beneficial graft versus tumor effects. Large numbers of hematopoietic cells can be collected with ease. Therefore, a renewable source of cells for ex vivo genetic manipulations is readily available. Multiple trials combining hematopoietic transplants and gene therapy are in progress. One such application is the infusion of allogeneic lymphocytes containing a suicide gene to abort graft versus host disease. Hematopoietic stem cell transplantation is in reality the clinical and practical application of cellular therapy. Hematopoietic transplant physicians are by design or by practical application evolving into cell and gene therapy specialists. The excitement and enthusiasm in hematopoietic transplantation is that it offers a door to the future. A future not of drugs or titrating poisonous chemotherapy but rather of cellular and gene therapy. 1 ALLOGENEIC PERIPHERAL BLOOD STEM CELL TRANSPLANTATION FOR HEMATOLOGIC DISEASES Martin Korbling University o/Texas MD. Anderson Cancer Center, Houston, Texas 77030 INTRODUCTION Circulating hematopoietic stem cells have emerged as an alternative to bone marrow (BM) stem cells for allografting. For many years the reconstitutive potential of circulating stem cells was questioned; peripheral blood stem cells (PBSC) were even characterized a waste product (1).

Diagnostic and Therapeutic Advances in Hematologic Malignancies

Martin S. Tallman,Leo I. Gordon
Diagnostic and Therapeutic Advances in Hematologic Malignancies Book PDF

Author : Martin S. Tallman,Leo I. Gordon
Publisher : Springer Science & Business Media
Page : 383 pages
File Size : 42,5 Mb
Release : 2007-11-23
Category : Medical
ISBN : 9780585385716

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Diagnostic and Therapeutic Advances in Hematologic Malignancies by Martin S. Tallman,Leo I. Gordon Pdf

There is no field of medicine in which advances in therapy have been so closely linked to a better understanding of molecular medicine than in the area of hematologic malignancies. Diagnostic and Therapeutic Advances in Hematologic Malignancies will provide practitioners and academic clinicians with a better understanding of the constant evolving concepts in this area.

Diagnostic and Therapeutic Advances in Pediatric Oncology

David O. Walterhouse,Susan L. Cohn
Diagnostic and Therapeutic Advances in Pediatric Oncology Book PDF

Author : David O. Walterhouse,Susan L. Cohn
Publisher : Springer Science & Business Media
Page : 388 pages
File Size : 53,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461557678

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Diagnostic and Therapeutic Advances in Pediatric Oncology by David O. Walterhouse,Susan L. Cohn Pdf

The purpose of Diagnostic and Therapeutic Advances in Pediatric Oncology for the Cancer Treatment and Research Series is to provide an up-to-date summary of how recent advances in cancer research are being applied to the care of children with solid tumors. The interface of cancer research with clinical practice in pediatric oncology has never been more intimate than today. While researchers are identifying oncogenes and tumor suppressor genes and are studying their specific functions, clinicians are using knowledge of oncogenes and tumor suppressor genes for diagnosing cancer in children, for therapeutic decision-making purposes, and for prognostic purposes. The first three chapters in this book describe models for understanding the causes of childhood cancer that were perhaps initially identified by clinicians and that are now being studied and understood by researchers. These chapters will describe research evidence that supports roles for the involvement of normal developmental regulatory genes in childhood oncogenesis, of abnormal immune regulation in childhood oncogenesis, and of heredity in childhood oncogenesis. The next eight chapters are devoted to descriptions of the appli cation of new research developments to clinical practice with reference to the most common forms of solid tumors of childhood outside the central nervous system. The final chapter will describe late effects of childhood cancer and its therapy and the impact research is having on understanding and perhaps preventing these late effects.

Drug Resistance

William N. Hait
Drug Resistance Book PDF

Author : William N. Hait
Publisher : Springer Science & Business Media
Page : 421 pages
File Size : 52,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461312673

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Drug Resistance by William N. Hait Pdf

Resistance to treatment represents the final common outcome for far too many patients with cancer. Even our most promising new drugs fall victim to drug resistance. Hormones and newer biological therapies, though safe and active, also lose their activity over time. In this volume of Drug Resistance, leading investigators in the field have reviewed the most basic mechanisms of drug resistance, and have proposed ways to modulate resistance. This comprehensive volume should be of value for basic and clinical scientists who wish to delve more deeply into this intriguing problem in the laboratory and devastating problem in the clinic.

Peritoneal Carcinomatosis: Principles of Management

Paul H. Sugarbaker
Peritoneal Carcinomatosis Principles of Management Book PDF

Author : Paul H. Sugarbaker
Publisher : Springer Science & Business Media
Page : 434 pages
File Size : 54,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461312475

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Peritoneal Carcinomatosis: Principles of Management by Paul H. Sugarbaker Pdf

Paul Sugarbaker and his colleagues have persevered in the study and treat ment of peritoneal carcinomatosis. The peritoneal cavity has many unique and incompletely appreciated properties. These properties, coupled with the biologic behavior of many cancers, results in the seeding and growth of these cancers on the peritoneum. Many of these cancers remain localized to the peritoneum only, never metastasizing to other sites. One possible reason for this may be the obstruction of the afferent lymphatics on the undersurface of the diaphragm. The mucopolysaccharides produced by many of these neoplasma are probably viscous enough to obstruct these lymphatics, leading to the syndrome of pseudomyxoma peritonei. Many of the neoplasms taking residence on the peritoneum have extremely long cell-cycle times and are resistant to radiotherapy and many chemotherapeutic agents. How ever, much can be done for these patients - resection of primary cancers, omentectomies to reduce ascites formation, management of recurrent ascites, management of intestinal obstruction, nutritional care, and, hopefully, intraperitoneal chemotherapy. We have reviewed many of these problems in the past [1-7]. Dr. Sugarbaker and his colleagues have organized the current state of knowledge and technology for continuing use. The book provides a basis for thoughtful, prospective research planning. John S. Spratt, M. D. , F. A. C. S. Professor of Surgery The James Graham Brown Cancer Center University of Louisville Louisville, Kentucky References 1. Long RTL, Spratt JS, Dowling E.