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Author : Anonim
Publisher : DIANE Publishing
Page : 66 pages
File Size : 45,9 Mb
Release : 2002
Category : Cancer
ISBN : NASA:31769000451685
Author : National Research Council,Division on Engineering and Physical Sciences,Space Studies Board,Committee for Evaluation of Space Radiation Cancer Risk Model
Publisher : National Academies Press
Page : 86 pages
File Size : 48,5 Mb
Release : 2012-03-19
Category : Science
ISBN : 9780309253086
NASA's current missions to the International Space Station (ISS) and potential future exploration missions involving extended stays by astronauts on the lunar surface, as well as the possibility of near- Earth object (NEO) or Mars missions, present challenges in protecting astronauts from radiation risks. These risks arise from a number of sources, including solar particle events (SPEs), galactic cosmic rays (GCRs), secondary radiation from surface impacts, and even the nuclear isotope power sources transported with the astronauts. The serious early and late radiation health effects potentially posed by these exposures are equally varied, ranging from early signs of radiation sickness to cancer induction. Other possible effects include central nervous system damage, cataracts, cardiovascular damage, heritable effects, impaired wound healing, and infertility. Recent research, much of which has been sponsored by NASA, has focused on understanding and quantifying the radiation health risks posed by space radiation environments. Although many aspects of the space radiation environments are now relatively well characterized, important uncertainties still exist regarding biological effects and thus regarding the level and types of risks faced by astronauts. This report presents an evaluation of NASA's proposed space radiation cancer risk assessment model, which is described in the 2011 NASA report, Space Radiation Cancer Risk Projections and Uncertainties-2010. The evaluation in Technical Evaluation of the NASA Model for Cancer Risk to Astronauts Due to Space Radiation considers the model components, input data (for the radiation types, estimated doses, and epidemiology), and the associated uncertainties. This report also identifies gaps in NASA's current research strategy for reducing the uncertainties in cancer induction risks.
Author : National Aeronautics and Space Adm Nasa
Publisher : Unknown
Page : 64 pages
File Size : 51,9 Mb
Release : 2018-09-21
Category : Electronic
ISBN : 1723888737
In this paper we discuss expected lifetime excess cancer risks for astronauts returning from exploration class missions. For the first time we make a quantitative assessment of uncertainties in cancer risk projections for space radiation exposures. Late effects from the high charge and energy (HZE) ions present in the galactic cosmic rays including cancer and the poorly understood risks to the central nervous system constitute the major risks. Methods used to project risk in low Earth orbit are seen as highly uncertain for projecting risks on exploration missions because of the limited radiobiology data available for estimating HZE ion risks. Cancer risk projections are described as a product of many biological and physical factors, each of which has a differential range of uncertainty due to lack of data and knowledge. Monte-Carlo sampling from subjective error distributions represents the lack of knowledge in each factor to quantify risk projection overall uncertainty. Cancer risk analysis is applied to several exploration mission scenarios. At solar minimum, the number of days in space where career risk of less than the limiting 3% excess cancer mortality can be assured at a 95% confidence level is found to be only of the order of 100 days.Cucinotta, Francis and Badhwar, Gautam and Saganti, Premkumar and Schimmerling, Walter and Wilson, John and Peterson, Leif and Dicello, JohnJohnson Space Center; Langley Research CenterASTRONAUTS; CANCER; GALACTIC COSMIC RAYS; RISK; SPACE EXPLORATION; PLANETARY ENVIRONMENTS; RADIATION HAZARDS; CONFIDENCE LIMITS; LOW EARTH ORBITS; MONTE CARLO METHOD; RADIOBIOLOGY; RADIATION DOSAGE; MORTALITY; IONS; SPACE MISSIONS; MANNED SPACE FLIGHT...
Author : National Research Council,Division on Engineering and Physical Sciences,Aeronautics and Space Engineering Board,Committee on the Evaluation of Radiation Shielding for Space Exploration
Publisher : National Academies Press
Page : 132 pages
File Size : 48,7 Mb
Release : 2008-05-29
Category : Science
ISBN : 9780309185721
As part of the Vision for Space Exploration (VSE), NASA is planning for humans to revisit the Moon and someday go to Mars. An important consideration in this effort is protection against the exposure to space radiation. That radiation might result in severe long-term health consequences for astronauts on such missions if they are not adequately shielded. To help with these concerns, NASA asked the NRC to further the understanding of the risks of space radiation, to evaluate radiation shielding requirements, and recommend a strategic plan for developing appropriate mitigation capabilities. This book presents an assessment of current knowledge of the radiation environment; an examination of the effects of radiation on biological systems and mission equipment; an analysis of current plans for radiation protection; and a strategy for mitigating the risks to VSE astronauts.
Author : National Research Council,Division on Engineering and Physical Sciences,Space Studies Board,Ad Hoc Committee on the Solar System Radiation Environment and NASA's Vision for Space Exploration: A Workshop
Publisher : National Academies Press
Page : 104 pages
File Size : 42,7 Mb
Release : 2006-11-10
Category : Science
ISBN : 9780309102643
Fulfilling the President's Vision for Space Exploration (VSE) will require overcoming many challenges. Among these are the hazards of space radiation to crews traveling to the Moon and Mars. To explore these challenges in some depth and to examine ways to marshal research efforts to address them, NASA, NSF, and the NRC sponsored a workshop bringing together members of the space and planetary science, radiation physics, operations, and exploration engineering communities. The goals of the workshop were to increase understanding of the solar and space physics in the environment of Earth, the Moon, and Mars; to identify compelling relevant research goals; and discuss directions this research should take over the coming decade. This workshop report presents a discussion of radiation risks for the VSE, an assessment of specifying and predicting the space radiation environment, an analysis of operational strategies for space weather support, and a summary and conclusions of the workshop.
Author : National Research Council,Division on Engineering and Physical Sciences,Space Studies Board,Ad Hoc Committee on the Solar System Radiation Environment and NASA's Vision for Space Exploration: A Workshop
Publisher : National Academies Press
Page : 104 pages
File Size : 50,8 Mb
Release : 2006-10-10
Category : Science
ISBN : 9780309180665
Fulfilling the President's Vision for Space Exploration (VSE) will require overcoming many challenges. Among these are the hazards of space radiation to crews traveling to the Moon and Mars. To explore these challenges in some depth and to examine ways to marshal research efforts to address them, NASA, NSF, and the NRC sponsored a workshop bringing together members of the space and planetary science, radiation physics, operations, and exploration engineering communities. The goals of the workshop were to increase understanding of the solar and space physics in the environment of Earth, the Moon, and Mars; to identify compelling relevant research goals; and discuss directions this research should take over the coming decade. This workshop report presents a discussion of radiation risks for the VSE, an assessment of specifying and predicting the space radiation environment, an analysis of operational strategies for space weather support, and a summary and conclusions of the workshop.
Author : Task Group on the Biological Effects of Space Radiation,Commission on Physical Sciences, Mathematics, and Applications,Space Studies Board,Division on Engineering and Physical Sciences,National Research Council
Publisher : National Academies Press
Page : 89 pages
File Size : 44,5 Mb
Release : 1997-03-13
Category : Science
ISBN : 9780309524292
NASA's long-range plans include possible human exploratory missions to the moon and Mars within the next quarter century. Such missions beyond low Earth orbit will expose crews to transient radiation from solar particle events as well as continuous high-energy galactic cosmic rays ranging from energetic protons with low mean linear energy transfer (LET) to nuclei with high atomic numbers, high energies, and high LET. Because the radiation levels in space are high and the missions long, adequate shielding is needed to minimize the deleterious health effects of exposure to radiation. The knowledge base needed to design shielding involves two sets of factors, each with quantitative uncertainty?the radiation spectra and doses present behind different types of shielding, and the effects of the doses on relevant biological systems. It is only prudent to design shielding that will protect the crew of spacecraft exposed to predicted high, but uncertain, levels of radiation and biological effects. Because of the uncertainties regarding the degree and type of radiation protection needed, a requirement for shielding to protect against large deleterious, but uncertain, biological effects may be imposed, which in turn could result in an unacceptable cost to a mission. It therefore is of interest to reduce these uncertainties in biological effects and shielding requirements for reasons of mission feasibility, safety, and cost.
Author : National Aeronautics and Space Administration (NASA)
Publisher : Createspace Independent Publishing Platform
Page : 44 pages
File Size : 42,7 Mb
Release : 2018-06-03
Category : Electronic
ISBN : 172061881X
This document addresses calculations of probability distribution functions (PDFs) representing uncertainties in projecting fatal cancer risk from galactic cosmic rays (GCR) and solar particle events (SPEs). PDFs are used to test the effectiveness of potential radiation shielding approaches. Monte-Carlo techniques are used to propagate uncertainties in risk coefficients determined from epidemiology data, dose and dose-rate reduction factors, quality factors, and physics models of radiation environments. Competing mortality risks and functional correlations in radiation quality factor uncertainties are treated in the calculations. The cancer risk uncertainty is about four-fold for lunar and Mars mission risk projections. For short-stay lunar missins (180 d) lunar or Mars missions, GCR risks may exceed radiation risk limits. While shielding materials are marginally effective in reducing GCR cancer risks because of the penetrating nature of GCR and secondary radiation produced in tissue by relativisitc particles, polyethylene or carbon composite shielding cannot be shown to significantly reduce risk compared to aluminum shielding. Therefore, improving our knowledge of space radiobiology to narrow uncertainties that lead to wide PDFs is the best approach to ensure radiation protection goals are met for space exploration.Cucinotta, Francis A. and Kim, Myung-Hee Y. and Ren, LeiJohnson Space CenterBIOASTRONAUTICS; RADIOBIOLOGY; RADIATION DOSAGE; PROBABILITY DISTRIBUTION FUNCTIONS; CANCER; RADIATION HAZARDS; ASTRONAUTS; LUNAR EXPLORATION; MARS EXPLORATION; MANNED MARS MISSIONS; LONG DURATION SPACE FLIGHT; MANNED SPACE FLIGHT; RISK; RADIATION SHIELDING; MONTE CARLO METHOD
Author : National Academies of Sciences Engineering and Medicine,Division on Earth and Life Studies,Health and Medicine Division,Nuclear and Radiation Studies Board,Board on Health Care Services,Board on Health Sciences Policy,Committee on Assessment of Strategies for Managing Cancer Risk Associated with Radiation Exposure During Crewed Space Missions
Publisher : Unknown
Page : 128 pages
File Size : 48,7 Mb
Release : 2022-03-24
Category : Electronic
ISBN : 0309479665
Astronauts face unique health-related risks during crewed space missions, and longer-duration missions that extend to greater distances in our solar system (including to the Moon and Mars) will likely increase those risks. Cancer risks due to ionizing radiation exposure are one of these health-related risks. Assessing, managing, and communicating radiation-induced cancer risks associated with spaceflight are challenging because of incomplete knowledge of the radiation environment in space, limited data on radiation-induced cellular damage mechanisms, lack of direct observations from epidemiological studies, and the complexities of understanding radiation risk. At the request of the National Aeronautics and Space Administration (NASA), an ad hoc committee of the National Academies of Sciences, Engineering, and Medicine convened to provide advice on NASA's proposed updates to their space radiation health standard, which sets the allowable limit of space radiation exposure throughout the course of an astronaut's career. Space Radiation and Astronaut Health: Managing and Communicating Cancer Risks provides the committee's recommendations and conclusions regarding the updated space radiation health standard, NASA's radiation risk communication strategies, and a process for developing an ethics-informed waiver protocol for long-duration spaceflight missions.
Author : National Research Council,Division on Engineering and Physical Sciences,Space Studies Board,Aeronautics and Space Engineering Board,Committee on Precursor Measurements Necessary to Support Human Operations on the Surface of Mars
Publisher : National Academies Press
Page : 65 pages
File Size : 47,8 Mb
Release : 2002-05-29
Category : Science
ISBN : 9780309169592
This study, commissioned by the National Aeronautics and Space Administration (NASA), examines the role of robotic exploration missions in assessing the risks to the first human missions to Mars. Only those hazards arising from exposure to environmental, chemical, and biological agents on the planet are assessed. To ensure that it was including all previously identified hazards in its study, the Committee on Precursor Measurements Necessary to Support Human Operations on the Surface of Mars referred to the most recent report from NASA's Mars Exploration Program/ Payload Analysis Group (MEPAG) (Greeley, 2001). The committee concluded that the requirements identified in the present NRC report are indeed the only ones essential for NASA to pursue in order to mitigate potential hazards to the first human missions to Mars.
Author : Anonim
Publisher : DIANE Publishing
Page : 64 pages
File Size : 40,6 Mb
Release : 2002
Category : Cancer
ISBN : 9781428995581
Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Creating a Vision for Space Medicine During Travel Beyond Earth Orbit
Publisher : National Academies Press
Page : 317 pages
File Size : 48,5 Mb
Release : 2001-11-20
Category : Science
ISBN : 9780309170314
Safe Passage: Astronaut Care for Exploration Missions sets forth a vision for space medicine as it applies to deep space voyage. As space missions increase in duration from months to years and extend well beyond Earth's orbit, so will the attendant risks of working in these extreme and isolated environmental conditions. Hazards to astronaut health range from greater radiation exposure and loss of bone and muscle density to intensified psychological stress from living with others in a confined space. Going beyond the body of biomedical research, the report examines existing space medicine clinical and behavioral research and health care data and the policies attendant to them. It describes why not enough is known today about the dangers of prolonged travel to enable humans to venture into deep space in a safe and sane manner. The report makes a number of recommendations concerning NASA's structure for clinical and behavioral research, on the need for a comprehensive astronaut health care system and on an approach to communicating health and safety risks to astronauts, their families, and the public.
Author : Alexander Choukèr
Publisher : Springer Nature
Page : 756 pages
File Size : 46,9 Mb
Release : 2019-11-27
Category : Medical
ISBN : 9783030169961
This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author : National Council on Radiation Protection and Measurements. SC 1-27 on Evaluation of Sex-Specific Differences in Lung Cancer Radiation Risks and Recommendations for Use in Transfer and Projection Models
Publisher : Unknown
Page : 0 pages
File Size : 47,8 Mb
Release : 2022
Category : Electronic
ISBN : 1944888330
"The study of Japanese atomic-bomb survivors exposed acutely to ionizing radiation in 1945 reported the risk of radiation-related lung cancer to be nearly three times greater for females than for males on a relative scale (similar for both mortality and incidence). The operational model for risk of exposure-induced death currently in use by the National Aeronautics and Space Administration (NASA) relies on data from the Japanese atomic-bomb survivor study. According to the NASA model, radiation-related lung cancer is the largest contributor to fatal cancer risk. The sex-specific difference in lung cancer observed for Japanese atomic-bomb survivors is used in the model, resulting in a higher estimated total cancer mortality risk for female astronauts than for male astronauts for the same level of exposure. NASA requested that the National Council on Radiation Protection and Measurements (NCRP) evaluate the risk of radiation-related lung cancer in populations exposed to chronic (protracted or fractionated) radiation, in order to investigate whether a similar sex- specific difference in lung cancer risk is observed when exposure occurs gradually over years (such as experienced by astronauts during space missions) contrasted with the acute exposure received by the Japanese atomic-bomb survivors"--
Author : Board on Health Sciences Policy,Institute of Medicine (U.S.). Committee on Ethics Principles and Guidelines for Health Standards for Long Duration and Exploration Spaceflights
Publisher : Unknown
Page : 0 pages
File Size : 40,9 Mb
Release : 2014
Category : Health & Fitness
ISBN : 0309296579
edicine to outline the ethics principles and practices that should guide the agency's decision making for future long duration or exploration missions that fail to meet existing health standards. Health Standards for Long Duration and Exploration Spaceflight identifies an ethics framework, which builds on the work of NASA and others, and presents a set of recommendations for ethically assessing and responding to the challenges associated with health standards for long duration and exploration spaceflight. As technologies improve and longer and more distant spaceflight becomes feasible, NASA and its international and commercial partners will continue to face complex decisions about risk acceptability. This report provides a roadmap for ethically assessing and responding to the challenges associated with NASA's health standards for long duration and exploration missions. Establishing and maintaining a firmly grounded ethics framework for this inherently risky activity is essential to gui