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Systemic Cellular And Molecular Mechanisms Of Physiological Functions And Their Disorders Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Systemic Cellular And Molecular Mechanisms Of Physiological Functions And Their Disorders book. This book definitely worth reading, it is an incredibly well-written.
Author : Nodar Prokof'evich Mitagvariia
Publisher : Unknown
Page : 128 pages
File Size : 45,7 Mb
Release : 2016
Category : MEDICAL
ISBN : 1634850149
Author : Nodar P. Mitagvaria,Nargiz N. Nachkebia
Publisher : Unknown
Page : 0 pages
File Size : 44,6 Mb
Release : 2018-10-19
Category : Physiology, Pathological
ISBN : 1536143952
The I. Beritashvili Center of Experimental Biomedicine was established in 2010 on the basis of merging four well-known Georgian research institutes. They are: The I. Beritashvili Institute of Physiology, one of the most prominent research centers of Georgia, where basic and applied research in different fields of neurophysiology has been conducted since 1935; the Institute of Molecular Biology and Biophysics; the Center for Radiology and Radiation Ecology, which for many years operated as departments at the I. Beritashvili Institute of Physiology; and one of the leading research centers for Georgia: The Center of Experimental Neurology. This edited book is the second volume containing chapters constituting the research priorities of the I. Beritashvili Center of Experimental Biomedicine and covers the experimental study of fundamental issues in the functioning of physiological (mainly, neurophysiological) mechanisms during normal and pathological conditions. The first book Cellular and Molecular Mechanisms of Physiological Functions and Their Disorders published by Nova Science Publishers Inc. in 2015, was also devoted to the same general problems. In the present edited book, particular attention is drawn to the study of extremely important processes underlying the basic mechanisms and disorders of various phenomenon of integrative activity of the brain: General behavior, learning and memory processes, the sleep-wakefulness cycle, regulation of adequate blood supply, hormesis, vision, depression, experimental comatose state, epilepsy, tumor diseases, pain and analgesia, the state of anxiety and aggression. All of the mentioned processes are studied on the molecular, cellular and systemic levels of their organization. It has to be noted herewith that each chapter within the collection of works represents the results of separate, independent studies implemented by different scientific departments of the Center; therefore, the chapters are not directly related to each other and have been arranged alphabetically based on the surnames of the authors. The authors would like to take this opportunity and present to the reader the scientific and institutional infrastructure of the Center, which consists of departments and laboratories. Nowadays, the Center is comprised of seven departments: Neurophysiology, Membranology, Biochemistry, Blood Circulation and Metabolism, Neurotoxicology, Biophysics and Radiobiology and nine laboratories: Behavior and Cognitive Functions, Physiology of Vision, Neurobiology of Sleep-Wakefulness Cycle, Ultra- and Nanoarchitectonics of the Brain, Experimental Neurology, Pain and Analgesia, Bioinformatics, Structure and Function of Genomes, and the Problems of Radiation Safety. In addition to bilateral scientific cooperation with many famous European and American scientific institutions, the Center is a member of the International Science Consortium From Molecular to Cellular Events in Human Pathologies, of which the 2015 Annual Meeting was held in Tbilisi. The authors are sure that readers are fully aware of the theoretical and practical importance of the research related to problems of systemic, cellular and molecular mechanisms of physiological functions and their disorders. The presented collection of works contains the results of relevant research conducted over the last three years (2015-2018). The authors will be very grateful for any feedback, recommendations and suggestions regarding their research for the implementation of which they have invested a lot of effort, time, knowledge and experience.
Author : Nodar Prokof'evich Mitagvariia,Nargiz G. Nachkebia
Publisher : Unknown
Page : 348 pages
File Size : 47,8 Mb
Release : 2018
Category : Medical
ISBN : 1536143960
The I. Beritashvili Center of Experimental Biomedicine was established in 2010 on the basis of merging four well-known Georgian research institutes. They are: The I. Beritashvili Institute of Physiology, one of the most prominent research centers of Georgia, where basic and applied research in different fields of neurophysiology has been conducted since 1935; the Institute of Molecular Biology and Biophysics; the Center for Radiology and Radiation Ecology, which for many years operated as departments at the I. Beritashvili Institute of Physiology; and one of the leading research centers for Georgia: The Center of Experimental Neurology.This edited book is the second volume containing chapters constituting the research priorities of the I. Beritashvili Center of Experimental Biomedicine and covers the experimental study of fundamental issues in the functioning of physiological (mainly, neurophysiological) mechanisms during normal and pathological conditions. The first book - Cellular and Molecular Mechanisms of Physiological Functions and Their Disorders - published by Nova Science Publishers Inc. in 2015, was also devoted to the same general problems.In the present edited book, particular attention is drawn to the study of extremely important processes underlying the basic mechanisms and disorders of various phenomenon of integrative activity of the brain: General behavior, learning and memory processes, the sleep-wakefulness cycle, regulation of adequate blood supply, hormesis, vision, depression, experimental comatose state, epilepsy, tumor diseases, pain and analgesia, the state of anxiety and aggression. All of the mentioned processes are studied on the molecular, cellular and systemic levels of their organization. It has to be noted herewith that each chapter within the collection of works represents the results of separate, independent studies implemented by different scientific departments of the Center; therefore, the chapters are not directly related to each other and have been arranged alphabetically based on the surnames of the authors. The authors would like to take this opportunity and present to the reader the scientific and institutional infrastructure of the Center, which consists of departments and laboratories.Nowadays, the Center is comprised of seven departments: Neurophysiology, Membranology, Biochemistry, Blood Circulation and Metabolism, Neurotoxicology, Biophysics and Radiobiology and nine laboratories: Behavior and Cognitive Functions, Physiology of Vision, Neurobiology of Sleep-Wakefulness Cycle, Ultra- and Nanoarchitectonics of the Brain, Experimental Neurology, Pain and Analgesia, Bioinformatics, Structure and Function of Genomes, and the Problems of Radiation Safety.In addition to bilateral scientific cooperation with many famous European and American scientific institutions, the Center is a member of the International Science Consortium "From Molecular to Cellular Events in Human Pathologies", of which the 2015 Annual Meeting was held in Tbilisi.The authors are sure that readers are fully aware of the theoretical and practical importance of the research related to problems of systemic, cellular and molecular mechanisms of physiological functions and their disorders. The presented collection of works contains the results of relevant research conducted over the last three years (2015-2018).The authors will be very grateful for any feedback, recommendations and suggestions regarding their research for the implementation of which they have invested a lot of effort, time, knowledge and experience.
Author : Nargiz Nachkebia
Publisher : Unknown
Page : 0 pages
File Size : 44,7 Mb
Release : 2021
Category : Brain
ISBN : 1685071139
The Ivane Beritashvili Center of Experimental Biomedicine was established in 2010 on the basis of the well-known Ivane Beritashvili Institute of Physiology, the most prominent research center of Georgia, where basic and applied research in different fields of neurophysiology has been conducted since its foundation.Professor Ivane Beritashvili was a famous Georgian scientist who gained international recognition during his lifetime. He was one of the founders and members of the Georgian Academy of Sciences and a member of three academies of sciences of the former Soviet Union. He was an honorary member of the New York Academy of Sciences, the American Society of Electroencephalography, the Royal Society of England, the American Society of Biological Psychiatry, and an honorary member of the International Brain Research Organization. He was an honored scientist of Georgia, a laureate of the State Prize, and a recipient of many orders and medals.Ivane Beritashvili is remembered in history as a person who founded the Department of Physiology at the newly opened Tbilisi State University. He developed physiological terminology in Georgian, wrote a textbook of physiology in Georgian for the students of the university, raised successful scientists from the first generation of his students, and founded the Georgian School of Physiology. In 1935, he founded the Institute of Physiology in Tbilisi, which soon gained recognition and became well-respected by a wide range of foreign scientists who often visited Georgia. In 2010, three scientific institutions were merged with the Ivane Beritashvili Institute of Physiology - the Institute of Molecular Biology and Biophysics, the Center of Radiobiology and Radiation Ecology and the Center of Experimental Neurology, the first two of which, for many years, were the departments of the Institute of Physiology. This edited book is the third such compilation containing chapters that represent the research priorities of the Ivane Beritashvili Center of Experimental Biomedicine, which covers the experimental study of fundamental issues in the functioning of physiological (mainly neurophysiological) mechanisms during normal and pathological conditions. The first and second books - "Systemic, Cellular and Molecular Mechanisms of Physiological Functions and Their Disorders" - published by Nova Science Publishers Inc. in 2015 and 2018, were also devoted to the same general problems.In the present edited book, particular attention is drawn to the study of extremely important processes underlying the basic mechanisms and disorders of various phenomenon of integrative activity of the brain: general behavior, learning and memory, the sleep-wakefulness cycle, regulation of adequate blood supply, hormesis, epilepsy, depression, sleep disorders, pain and analgesia. All of the mentioned processes are studied on the molecular, cellular and systemic levels of their organization. It has to be noted that each chapter, within the collection of works, represents the results of separate, independent studies implemented by different scientific departments of the center. Therefore, the chapters are not directly related to each other and have been arranged alphabetically based on the surname of the authors. The authors would like to take this opportunity to present to the reader the scientific and institutional infrastructure of the center, which consists of departments and laboratories. Nowadays the center consists of seven departments: Neurophysiology, Membranology, Biochemistry, Blood Circulation and Metabolism, Neurotoxicology, Membranology, Biophysics and Radiobiology and nine laboratories: Neurobiology of Sleep-Wakefulness Cycle, Vision Physiology, Behavior and Cognitive Functions, Brain Ultra- and Nano-Architectonics, Experimental Neurology, Pain and Analgesia, Structure and Functions of Genomes, Bioinformatics, and the Problems of Radiation Safety.In addition to the bilateral scientific cooperation with famous European and U.S. scientific institutions, the center is a member of the International Science Consortium "From Molecule to Cellular Events in Human Pathologies", the annual meeting of which was held in Tbilisi in 2015.The authors are confident that the readers are fully aware of the theoretical and practical importance of the research related to the problems of systemic, cellular and molecular mechanisms of physiological functions and their disorders. The presented collection of works contains the results of relevant research conducted over the last three years (2019-2021).The authors will be grateful for feedback, recommendations and suggestions regarding their research, in the implementation of which they have invested a lot of effort, knowledge and experience.
Author : Alfredo Ulloa-Aguirre,Ya-Xiong Tao
Publisher : Academic Press
Page : 488 pages
File Size : 48,7 Mb
Release : 2021-02-02
Category : Science
ISBN : 9780128198025
Cellular Endocrinology in Health and Disease, Second Edition, describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. The new edition provides an understanding of how endocrine glands function by integrating information resulting in biological effects on both local and systemic levels, also providing new information on the molecular physiopathogenesis of endocrine neoplasic cells. The new edition expands the most used chapters from the first edition and proposes a series of substitutions and additions to the table of contents. New chapters cover signaling, brown adipose tissue, hypothalamic cell models, cellular basis of insulin resistance, genetics and epigenetics of neuroendocrine tumors, and a series of chapters on endocrine-related cancer. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease, Second Edition, details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and Ya-Xiong Tao, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts Explores endocrine cells biology in normal and pathologic conditions Covers new aspects of endocrine cell function in distinct tissues Provides a view into the biological effect in local and systemic levels 15 new chapters covering the recent developments in the field
Author : Tara Karimi
Publisher : Springer
Page : 134 pages
File Size : 50,9 Mb
Release : 2018-07-28
Category : Science
ISBN : 9783319918242
This book presents a novel molecular description for understanding the regulatory mechanisms behind the autonomy and self-organization in biological systems. Chapters focus on defining and explaining the regulatory molecular mechanisms behind different aspects of autonomy and self-organization in the sense of autonomous coding, data processing, structure (mass) formation and energy production in a biological system. Subsequent chapters discuss the cross-talk among mechanisms of energy, and mass and information, transformation in biological systems. Other chapters focus on applications regarding therapeutic approaches in regenerative medicine. Molecular Mechanisms of Autonomy in Biological Systems is an indispensable resource for scientists and researchers in regenerative medicine, stem cell biology, molecular biology, tissue engineering, developmental biology, biochemistry, biophysics, bioinformatics, as well as big data sciences, complexity and soft computing.
Author : Chunheng Mo,Xiao Xiao Tang,Shigeyuki Shichino,Gianluca Bagnato
Publisher : Frontiers Media SA
Page : 123 pages
File Size : 41,6 Mb
Release : 2024-01-23
Category : Science
ISBN : 9782832543252
Organ fibrosis seriously threatens human health. Globally, more than 30% of the diseases that cause disability and death are due to organ fibrosis. However, there have been so far only a few effective treatments for organ fibrosis. Idiopathic pulmonary fibrosis (IPF) is progressive, lethal fibrotic lung disease. Approximately, 10/100,000 people globally suffer from pulmonary fibrosis, and the incidence is on the rise. The median survival for patients is only 3-5 years. Currently there is no effective treatment for lung fibrosis. Therefore, new insights into lung fibrosis and therapeutic strategy should be explored and developed. This Research Topic aims to deepen the understanding and research on the pathogenesis of lung fibrosis to develop effective treatments. Studies have shown that effective lung repair and regeneration are critical biological processes for the restoration of original physiological function of lung after injury. The intrinsic ability of regeneration and repair is often suppressed in lung with chronic injury or the diseased organs, leading to fibrosis and loss of function. Targeting key pathways in the process of lung regeneration can promote the repair of the impaired lung and alleviate fibrosis in animal models. How to induce regeneration and repair of the impaired organ to alleviate fibrosis is a frontier research topic. Hence, this Research Topic focuses on the cellular and molecular mechanisms of lung regeneration, repair, and fibrosis. Moreover, this topic will also focus on the study of lung development to provide new insights into the pathogenesis of lung injury and fibrosis.
Author : Anonim
Publisher : Unknown
Page : 826 pages
File Size : 54,6 Mb
Release : 1987
Category : Medicine
ISBN : MINN:30000008773602
Author : Anonim
Publisher : Elsevier
Page : 5000 pages
File Size : 54,8 Mb
Release : 2014-08-01
Category : Medical
ISBN : 9780123864574
Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human Organ Systems Molecular Pathology/Basic Mechanisms of Diseases Animal Models/Other Model Systems Experimental Pathology Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "Normal" and "Disease" anatomy and histology images Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions
Author : Hamid M. Said
Publisher : Academic Press
Page : 2250 pages
File Size : 53,5 Mb
Release : 2012-07-04
Category : Medical
ISBN : 9780123820273
Physiology of the Gastrointestinal Tract, Fifth Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine — covers the study of the mechanical, physical, and biochemical functions of the GI Tract while linking the clinical disease or disorder, bridging the gap between clinical and laboratory medicine. The gastrointestinal system is responsible for the breakdown and absorption of various foods and liquids needed to sustain life. Other diseases and disorders treated by clinicians in this area include: food allergies, constipation, chronic liver disease and cirrhosis, gallstones, gastritis, GERD, hemorrhoids, IBS, lactose intolerance, pancreatic, appendicitis, celiac disease, Crohn’s disease, peptic ulcer, stomach ulcer, viral hepatitis, colorectal cancer and liver transplants. The new edition is a highly referenced and useful resource for gastroenterologists, physiologists, internists, professional researchers, and instructors teaching courses for clinical and research students. 2013 Highly Commended BMA Medical Book Award for Internal Medicine Discusses the multiple processes governing gastrointestinal function Each section edited by preeminent scientist in the field Updated, four-color illustrations
Author : M. Donald McGavin
Publisher : Mosby
Page : 0 pages
File Size : 47,9 Mb
Release : 2007
Category : Medical
ISBN : 0323028705
The 4th edition of this textbook, now in full color, presents both general pathology and special pathology in one comprehensive resource. Coverage includes a brief review of basic principles related to anatomy, structure and function, followed by congenital and functional abnormalities and discussions of viral, bacterial, and parasitic infections and neoplasia. Logically organized chapters discuss normal functions of the body system, followed by pathologic conditions found in domestic and companion animals. While focusing primarily on diseases in North America, the text also includes pathologic conditions found in other parts of the world, as well as those being brought into this country, such as West Nile virus, through the importation of cattle, sheep, and other animals. Contributors are recognized in their area of expertise and are well known in research and education. Now in full color throughout with vivid new illustrations that clarify difficult concepts. Includes six new chapters covering general pathology that discuss topics such as cellular and tissue responses to injury, vascular disorders, inflammation, and tumor biology. All chapters emphasize mechanisms of disease (organ, tissue, cell, and molecular injury). Features sequential presentations of disease processes (portal of entry * target cells * cellular injury * visual appearance of injury * resolution of injury * clinical outcomes). Emphasizes portals of entry for microbes and injurious agents. Focuses on defense mechanisms against microbes and injurious agents.
Author : William C. Wilson,Christopher M. Grande,David B. Hoyt
Publisher : CRC Press
Page : 1386 pages
File Size : 40,9 Mb
Release : 2007-02-05
Category : Medical
ISBN : 9781420016840
Compiled by internationally recognized experts in trauma critical care,this sourcediscusses the entire gamut of critical care management of the trauma patient and covers several common complications and conditions treated in surgical intensive care units that are not specifically related to trauma. Utilizing evidence-based guidelines where they ex
Author : Xiaonan Dong,Zvulun Elazar
Publisher : Frontiers Media SA
Page : 133 pages
File Size : 42,9 Mb
Release : 2023-06-05
Category : Science
ISBN : 9782832524916
Author : Scott Brady,George Siegel,R. Wayne Albers,Donald Price
Publisher : Academic Press
Page : 1120 pages
File Size : 46,5 Mb
Release : 2011-11-02
Category : Science
ISBN : 9780080959016
Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. It is also an excellent source of current information on basic biochemical and cellular processes in brain function and neurological diseases for continuing medical education and qualifying examinations. This text continues to be the standard reference and textbook for exploring the translational nature of neuroscience, bringing basic and clinical neuroscience together in one authoritative volume. Our book title reflects the expanded attention to these links between neurochemistry and neurologic disease. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from: Intracellular trafficking; Stem cells, adult neurogenesis, regeneration; Lipid messengers; Expanded coverage of all major neurodegenerative and psychiatric disorders; Neurochemistry of addiction; Neurochemistry of pain; Neurochemistry of hearing and balance; Neurobiology of learning and memory; Sleep; Myelin structure, development, and disease; Autism; and Neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at http://elsevierdirect.com/companions/9780123749475
Author : National Heart, Lung, and Blood Institute
Publisher : Unknown
Page : 622 pages
File Size : 53,5 Mb
Release : 1978
Category : Cardiovascular system
ISBN : STANFORD:36105223074068
