Target Volume Delineation For Pediatric Cancers

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Target Volume Delineation for Pediatric Cancers

Stephanie A. Terezakis,Shannon M. MacDonald
Target Volume Delineation for Pediatric Cancers Book PDF

Author : Stephanie A. Terezakis,Shannon M. MacDonald
Publisher : Springer
Page : 282 pages
File Size : 46,6 Mb
Release : 2018-12-31
Category : Medical
ISBN : 9783319691404

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Target Volume Delineation for Pediatric Cancers by Stephanie A. Terezakis,Shannon M. MacDonald Pdf

This handbook is designed to provide the radiation oncologist with clear practical guidance in the delineation of tumor volumes and/or radiation fields for a wide variety of pediatric cancers, including the most frequently encountered malignancies of childhood. This is a guide to designing treatment fields and volumes that may be utilized in the delivery of conformal therapies such as intensity-modulated radiation therapy and proton therapy, the latter being particularly relevant in children. Each chapter focuses on a specific tumor type, providing general guidelines that will assist the reader in delineating the clinical target volume for particular presentations, including patterns of spread. As the target volumes can be complex, detailed illustrations are presented of the volumes in representative cases, contoured slice by slice on the planning CT images. In addition to target volume delineation for conformal treatment, field design setup for conventional approaches is also discussed.

Pediatric Radiation Oncology

Thomas E. Merchant,Rolf-Dieter Kortmann
Pediatric Radiation Oncology Book PDF

Author : Thomas E. Merchant,Rolf-Dieter Kortmann
Publisher : Springer
Page : 462 pages
File Size : 41,6 Mb
Release : 2018-03-01
Category : Medical
ISBN : 9783319435459

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Pediatric Radiation Oncology by Thomas E. Merchant,Rolf-Dieter Kortmann Pdf

This book presents the most up-to-date and innovative information on the targeting and treatment of a wide range of childhood cancers by means of radiation therapy. Written by global experts in pediatric radiation oncology, it documents in detail the treatment regimens appropriate to each disease, highlighting the recent advances that promise to improve rates of survival and cure. The use of image-guided and intensity-modulated radiation therapy is clearly described, and careful attention is also devoted to the roles of proton therapy, stereotactic radiosurgery, stereotactic fractionated radiosurgery, and modulated arc radiotherapy. Separate chapters address localization and verification procedures and anesthesia; pediatric radiation oncology in the palliative care setting; and aspects that are especially relevant in low- and medium-income countries. Beyond clinical radiation oncology, relevant information is provided on radiation physics. The book concludes by examining future directions in the field.

Principles and Practice of Pediatric Oncology

Philip A. Pizzo,David G. Poplack
Principles and Practice of Pediatric Oncology Book PDF

Author : Philip A. Pizzo,David G. Poplack
Publisher : Lippincott Williams & Wilkins
Page : 5113 pages
File Size : 52,5 Mb
Release : 2015-06-24
Category : Medical
ISBN : 9781496318763

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Principles and Practice of Pediatric Oncology by Philip A. Pizzo,David G. Poplack Pdf

Now thoroughly updated to include new advances in the field,and with regular content updates to the eBook, Principles and Practice of Pediatric Oncology, 7th Edition remains the gold standard text for the care and research of children with cancer. This authoritative reference is the single most comprehensive resource on the biology and genetics of childhood cancer and the diagnosis, multimodal treatment, and long-term management of young patients with cancer. Also addressed are a broad array of topics on the supportive and psychosocial aspects of care of children and families. Covering virtually every aspect of the breadth and depth of childhood cancer, this 7th Edition provides expert guidance on state-of-the-art, multidisciplinary care for children and families. Stay up to date with the most recent advances in the field with the contributions by new and returning contributors, including the perspective from patients and parents in the chapter titled “The Other Side of the Bed.” Reference your eBook version for key updates in the field during the life of the edition! Chapters included on palliative care and education. Supportive care is covered broadly and specifically – in contexts such as emergencies, infectious disease, and nutrition. The most updated and authoritative information is provided by the leading experts in the field. Gain a thorough understanding of every aspect of pediatric oncology, with comprehensive information regarding basic science, diagnostic tools, principles of treatment, and clinical trials, as well as highly detailed, definitive coverage of each pediatric malignancy. Collaborate more effectively with others on the cancer care team to enhance quality-of-life issues for patients and families. Understand the cooperative nature of pediatric oncology as a model for cancer research with information from cooperative clinical trial groups and consortia.

Molecularly Targeted Therapy for Childhood Cancer

Peter J. Houghton,Robert J. Arceci
Molecularly Targeted Therapy for Childhood Cancer Book PDF

Author : Peter J. Houghton,Robert J. Arceci
Publisher : Springer
Page : 0 pages
File Size : 41,9 Mb
Release : 2014-08-23
Category : Medical
ISBN : 148998142X

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Molecularly Targeted Therapy for Childhood Cancer by Peter J. Houghton,Robert J. Arceci Pdf

Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular ‘drivers’ can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered. This volume will provide a comprehensive summary of molecular characteristics of childhood cancers, and how the changes involved in transformation provide us with opportunities for developing relatively less toxic, but curative, therapies.

Target Volume Delineation and Field Setup

Nancy Y. Lee,Jiade J. Lu
Target Volume Delineation and Field Setup Book PDF

Author : Nancy Y. Lee,Jiade J. Lu
Publisher : Springer Science & Business Media
Page : 310 pages
File Size : 51,9 Mb
Release : 2012-09-18
Category : Medical
ISBN : 9783642288609

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Target Volume Delineation and Field Setup by Nancy Y. Lee,Jiade J. Lu Pdf

This handbook will enable radiation oncologists to appropriately and confidently select and delineate tumor volumes/fields for conformal radiation therapy, including intensity-modulated radiation therapy (IMRT), in patients with commonly encountered cancers. The orientation of this handbook is entirely practical, in that the focus is on the illustration of clinical target volume (CTV) delineation for each major malignancy. Each chapter provides guidelines and concise knowledge on treatment planning and CTV selection, explains how the anatomy of lymphatic drainage shapes target volume selection, and presents detailed illustrations of delineations, slice by slice, on planning CT images. While the emphasis is on target volume delineation for three-dimensional conformal therapy and IMRT, information is also provided on conventional radiation therapy field setup and planning for certain malignancies for which IMRT is not currently suitable.

Handbook of Cancer Treatment-Related Symptoms and Toxicities

Vamsidhar Velcheti,Salman R Punekar
Handbook of Cancer Treatment Related Symptoms and Toxicities Book PDF

Author : Vamsidhar Velcheti,Salman R Punekar
Publisher : Elsevier Health Sciences
Page : 355 pages
File Size : 49,9 Mb
Release : 2021-01-28
Category : Medical
ISBN : 9780323672993

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Handbook of Cancer Treatment-Related Symptoms and Toxicities by Vamsidhar Velcheti,Salman R Punekar Pdf

Early recognition and management of adverse effects of cancer treatments are essential for optimal care of patients with cancer, and drastically different approaches are required for different physiologic reactions. Handbook of Cancer Treatment-Related Symptoms and Toxicities is a focused, one-stop resource that enables clinicians to quickly find up-to-date, reliable information needed at the point of care. The high-yield approach prioritizes the most common toxicities associated with cancer treatment, and concise, templated chapters offer fast access to information needed in day-to-day practice. Presents a user-friendly overview of cancer treatment-related symptoms and toxicities management in a practical, easy-to-use format, allowing you to quickly find information in one convenient, concise resource. Covers systemic and radiation therapies, including chemotherapy, immunotherapy, targeted therapies, and radiation therapy, detailing symptoms of each toxicity to confirm your diagnosis. Overviews pharmacologic and non-pharmacologic approaches to symptom management. Offers recommendations for mitigating toxicities in high-risk patients. Discusses key topics such as management of infusion reactions, when the need for biopsy is warranted, and the unique challenges posed by novel immunotherapies.

Targeted Therapies for Solid Tumors

Antonio Russo,Rafael Rosell,Christian Rolfo
Targeted Therapies for Solid Tumors Book PDF

Author : Antonio Russo,Rafael Rosell,Christian Rolfo
Publisher : Humana Press
Page : 269 pages
File Size : 45,5 Mb
Release : 2015-03-11
Category : Medical
ISBN : 9781493920471

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Targeted Therapies for Solid Tumors by Antonio Russo,Rafael Rosell,Christian Rolfo Pdf

This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current available literature. Written by recognized experts in the field, Targeted Therapies for Solid Tumors: A Handbook for Moving Toward New Frontiers in Cancer Treatment provides a unique and valuable resource in the field of molecular oncology, both for those currently in training, and for those already in clinical or research practice.

Target Volume Delineation for Conformal and Intensity-Modulated Radiation Therapy

Nancy Y. Lee,Nadeem Riaz,Jiade J. Lu
Target Volume Delineation for Conformal and Intensity Modulated Radiation Therapy Book PDF

Author : Nancy Y. Lee,Nadeem Riaz,Jiade J. Lu
Publisher : Springer
Page : 541 pages
File Size : 55,6 Mb
Release : 2014-12-08
Category : Medical
ISBN : 9783319057262

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Target Volume Delineation for Conformal and Intensity-Modulated Radiation Therapy by Nancy Y. Lee,Nadeem Riaz,Jiade J. Lu Pdf

This textbook is designed to help the busy radiation oncologist to accurately and confidently delineate tumor volumes for conformal radiation therapy (including IMRT). The book provides an atlas of clinical target volumes (CTVs) for commonly encountered cancers, with each chapter illustrating CTV delineation on a slice-by-slice basis, on planning CT images. Common anatomic variants for each tumor are represented in individual illustrations, with annotations highlighting differences in coverage. The anatomy of each site and patterns of lymphatic drainage are discussed, and their influence on the design of CTVs is explained in detail. Utilization of other imaging modalities, including MRI, to delineate volumes is highlighted. Key details of simulation and planning are briefly reviewed. Although the emphasis is on target volume delineation for conformal techniques, information is also provided on conventional radiation field setup and design when IMRT is not suitable.

Radiation Oncology Study Guide

Ravi A. Chandra,Celine B. Ord,Shushan Rana,Eric K. Hansen,Charles R. Thomas, Jr.
Radiation Oncology Study Guide Book PDF

Author : Ravi A. Chandra,Celine B. Ord,Shushan Rana,Eric K. Hansen,Charles R. Thomas, Jr.
Publisher : Springer Nature
Page : 668 pages
File Size : 52,7 Mb
Release : 2020-11-16
Category : Medical
ISBN : 9783030536879

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Radiation Oncology Study Guide by Ravi A. Chandra,Celine B. Ord,Shushan Rana,Eric K. Hansen,Charles R. Thomas, Jr. Pdf

Now in its second edition, this popular text remains a comprehensive study and review aid for the radiation oncology trainee and practicing radiation oncologist. The updated Radiation Oncology Study Guide, 2e maintains its robust Q&A format, and has been comprehensively updated to include the latest staging information and treatment methods. Answer rationales have been modified to a more readable, high yield bulleted format. Each chapter covers a major disease site and is divided into two main parts: Questions & Answers and Rationale. Questions review the scope of clinical practice, spanning from initial presentation to complications of treatment. General content and work-up questions emphasize “pearls” of epidemiology, anatomy, pathology, clinical presentation, and staging. Treatment content questions not only review evidence-based data guiding treatment recommendations, but also practical aspects of radiation treatment planning, pertinent radiobiology and physics, and complications of treatment. This book is an ideal resource for physicians-in-training to prepare for initial written and oral exams and physicians in practice to maintain their skills and prepare for maintenance of certification longitudinal and written exams.

Autophagy and Cancer

Hong-Gang Wang
Autophagy and Cancer Book PDF

Author : Hong-Gang Wang
Publisher : Springer Science & Business Media
Page : 267 pages
File Size : 50,6 Mb
Release : 2013-03-30
Category : Medical
ISBN : 9781461465614

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Autophagy and Cancer by Hong-Gang Wang Pdf

With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy − what to target and how to target it. ​

Target Volume Delineation and Treatment Planning for Particle Therapy

Nancy Y. Lee,Jonathan E. Leeman,Oren Cahlon,Kevin Sine,Guoliang Jiang,Jiade J. Lu,Stefan Both
Target Volume Delineation and Treatment Planning for Particle Therapy Book PDF

Author : Nancy Y. Lee,Jonathan E. Leeman,Oren Cahlon,Kevin Sine,Guoliang Jiang,Jiade J. Lu,Stefan Both
Publisher : Springer
Page : 396 pages
File Size : 42,5 Mb
Release : 2017-12-19
Category : Medical
ISBN : 9783319424781

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Target Volume Delineation and Treatment Planning for Particle Therapy by Nancy Y. Lee,Jonathan E. Leeman,Oren Cahlon,Kevin Sine,Guoliang Jiang,Jiade J. Lu,Stefan Both Pdf

This handbook is designed to enable radiation oncologists to treat patients appropriately and confidently by means of particle therapy. The orientation and purpose are entirely practical, in that the focus is on the physics essentials of delivery and treatment planning , illustration of the clinical target volume (CTV) and associated treatment planning for each major malignancy when using particle therapy, proton therapy in particular. Disease-specific chapters provide guidelines and concise knowledge on CTV selection and delineation and identify aspects that require the exercise of caution during treatment planning. The treatment planning techniques unique to proton therapy for each disease site are clearly described, covering beam orientation, matching/patching field techniques, robustness planning, robustness plan evaluation, etc. The published data on the use of particle therapy for a given disease site are also concisely reported. In addition to fully meeting the needs of radiation oncologists, this "know why" and “know how” guide to particle therapy will be valuable for medical physicists, dosimetrists, and radiation therapists.

Renal Tumors of Childhood

Kathy Pritchard-Jones,Jeffrey S. Dome
Renal Tumors of Childhood Book PDF

Author : Kathy Pritchard-Jones,Jeffrey S. Dome
Publisher : Springer
Page : 0 pages
File Size : 50,5 Mb
Release : 2016-10-06
Category : Medical
ISBN : 3662519186

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Renal Tumors of Childhood by Kathy Pritchard-Jones,Jeffrey S. Dome Pdf

This book provides a comprehensive overview of the biological basis of renal tumors in childhood and the clinical approaches to their treatment. Recent advances in our understanding of the molecular genetics of Wilms and other renal tumors are placed in their clinical context, including the differing treatment approaches of immediate surgery or pre-operative chemotherapy. The challenges in applying this knowledge to improve risk stratification and to incorporate biologically targeted agents into front-line therapy are discussed. All of the authors are experts from Europe and North America and the book has been written specifically as an easy reference for the practising clinician and the research scientist. It lays the basis for understanding the future direction of clinical and translational research to improve outcomes in patients with childhood renal tumors and will prove indispensable for those treating or researching into these diseases.

Epidemiology of Brain and Spinal Tumors

Jahangir Moini,Nicholas Avgeropoulos,Mohtashem Samsam
Epidemiology of Brain and Spinal Tumors Book PDF

Author : Jahangir Moini,Nicholas Avgeropoulos,Mohtashem Samsam
Publisher : Academic Press
Page : 554 pages
File Size : 51,6 Mb
Release : 2021-04-09
Category : Medical
ISBN : 9780128217559

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Epidemiology of Brain and Spinal Tumors by Jahangir Moini,Nicholas Avgeropoulos,Mohtashem Samsam Pdf

Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors. Provides the most up-to-date information surrounding the epidemiology, biology and imaging techniques for brain and spinal tumors, including CT, MRI, PET, and others Includes full color figures, photos, tables, graphs and radioimaging Contains information that will be valuable to anyone interested in the field of neurooncology and the treatment of patients with brain and spinal tumors Serves as a source of background information for basic scientists and pharmaceutical researchers who have an interest in imaging and treatment

Myeloproliferative Neoplasms

Tiziano Barbui,Ayalew Tefferi
Myeloproliferative Neoplasms Book PDF

Author : Tiziano Barbui,Ayalew Tefferi
Publisher : Springer Science & Business Media
Page : 235 pages
File Size : 47,8 Mb
Release : 2012-02-03
Category : Medical
ISBN : 9783642249884

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Myeloproliferative Neoplasms by Tiziano Barbui,Ayalew Tefferi Pdf

This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.

Absolute Clinical Radiation Oncology Review

Daniel M. Trifiletti,Nicholas G. Zaorsky
Absolute Clinical Radiation Oncology Review Book PDF

Author : Daniel M. Trifiletti,Nicholas G. Zaorsky
Publisher : Springer
Page : 492 pages
File Size : 44,5 Mb
Release : 2019-01-22
Category : Medical
ISBN : 9783319968094

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Absolute Clinical Radiation Oncology Review by Daniel M. Trifiletti,Nicholas G. Zaorsky Pdf

This book provides a quick reference guide for clinicians in radiation oncology. It is designed to be an intuitive and easily reviewed study guide for board or maintenance of certification examinations, as well as a quick reference for residents and established radiation oncologists who need a refresher. The text begins with a general pearls chapter that radiation oncologists should consider in all aspects of their practice, including cancer visibility, dosing, counseling recommendations, and toxicity management. The subsequent chapters then delve into different cancer disease sites, including pediatrics, central nervous system, head and neck, thoracic, breast, gastrointestinal, gynecologic, genitourinary, hematologic, soft tissue, palliative, and radiophysics/radiobiology. Within each chapter, each disease and its recommended approach is then summarized in only a few pages, allowing a focus on the most essential information. Bullet points, figures, tables, and images make for an intuitive reader experience. Recommendations are taken from the American Society for Radiation Oncology (ASTRO), the European Society for Radiation Oncology (ESTRO), and the National Comprehensive Cancer Network (NCCN). Planning guides for imaging, diagnosis, and staging offer readers a starting point in approaching each patient based on disease origin, and dosing guidelines then detail consideration for treatment methods. Each chapter additionally includes disease-specific pearls and key points to test the knowledge reviewed in the chapters. Experts in the disease sites from the United States serve as senior authors on each chapter. The authors include all diseases associated with radiation oncology training to ensure a comprehensive resource for exam studying and clinical care. Residents, trainees, and established radiation oncologists find this an ideal study resource for both board and certification exams, as well as an easily accessible aid during practice.