Targeted Cancer Therapy In Biomedical Engineering

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Targeted Cancer Therapy in Biomedical Engineering

Rishabha Malviya,Sonali Sundram
Targeted Cancer Therapy in Biomedical Engineering Book PDF

Author : Rishabha Malviya,Sonali Sundram
Publisher : Springer Nature
Page : 949 pages
File Size : 55,5 Mb
Release : 2023-04-11
Category : Science
ISBN : 9789811997860

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Targeted Cancer Therapy in Biomedical Engineering by Rishabha Malviya,Sonali Sundram Pdf

This book highlights the role of Biomedical Engineering (BME) used in diagnosis (e.g., body scanners) and treatment (radiation therapy and minimal access surgery in order to prevent various diseases). In recent years, an important progress has been made in the expansion of biomedical microdevices which has a major role in diagnosis and therapy of cancer. When fighting cancer, efficacy and speed are of the utmost importance. A recently developed microfluidic chip has enabled a breakthrough in testing the efficacy of specialized cancer drugs. Effective cancer-targeting therapies will require both passive and active targeting strategies and a thorough understanding of physiologic barriers to targeted drug delivery. Targeted cancer treatments in development and the new combinatorial approaches show promise for improving targeted anticancer drug delivery and improving treatment outcomes. This book discusses the advancements and innovations in the field of BME that improve the diagnosis and treatment of cancer. This book is focused on bioengineering approaches to improve targeted delivery for cancer therapeutics, which include particles, targeting moieties, and stimuli-responsive drug release mechanisms. This book is a useful resource for students, researchers, and professionals in BME and medicine.

Bio-Engineering Approaches to Cancer Diagnosis and Treatment

Azadeh Shahidian,Majid Ghassemi,Javad Mohammadi,Mohadeseh Hashemi
Bio Engineering Approaches to Cancer Diagnosis and Treatment Book PDF

Author : Azadeh Shahidian,Majid Ghassemi,Javad Mohammadi,Mohadeseh Hashemi
Publisher : Academic Press
Page : 276 pages
File Size : 42,7 Mb
Release : 2020-05-14
Category : Technology & Engineering
ISBN : 9780128178102

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Bio-Engineering Approaches to Cancer Diagnosis and Treatment by Azadeh Shahidian,Majid Ghassemi,Javad Mohammadi,Mohadeseh Hashemi Pdf

Bioengineering Approaches to Cancer Diagnosis and Treatment is written for an audience of senior undergraduate students and graduate students in mechanical, electrical and biomedical engineering fields and other professionals in medicine. It is ideally structured for teaching and for those who are working in cancer bioengineering or interdisciplinary projects. The book's authors bring a unique perspective from their expertise in immunology, nanobiomaterials and heat transfer. Topical coverage includes an introduction to the fundamentals of bioengineering and engineering approaches for cancer diagnosis, cancer treatment via case studies, and sections on imaging, immunotherapy, cell therapy, drug delivery, ultrasound and microfluidics in cancer treatment. Provides fully supported case studies relating to cancer diagnosis and therapy Pairs the basic fundamentals of engineering and biomedical engineering and applies them to the diagnosis of cancer

Bioengineering Innovative Solutions for Cancer

Sylvain Ladame,Jason Chang
Bioengineering Innovative Solutions for Cancer Book PDF

Author : Sylvain Ladame,Jason Chang
Publisher : Academic Press
Page : 396 pages
File Size : 40,6 Mb
Release : 2019-11-27
Category : Science
ISBN : 9780128138878

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Bioengineering Innovative Solutions for Cancer by Sylvain Ladame,Jason Chang Pdf

Bioengineering Innovative Solutions for Cancer bridges the gap between bioengineering and cancer biology. It focuses on a ‘bottom up’ understanding of the links between molecules, cells, tissues, organs, organisms, and health and functions—all within a bioengineering context. Chapters cover the main methods, technologies and devices that could help diagnose cancer sooner (e.g., ultrasensitive imaging and sensing technologies) and helpful treatments (e.g., new, more targeted therapies). The book takes an interdisciplinary approach that is ideal for those who need the latest information on design techniques and devices that help treat cancer using new, more targeted therapies. By covering the many different ways engineers can deliver innovative solutions to tackle cancer, this book is a valuable read for researchers who have an ambition to make an impact on people’s life in either an academic or industrial setting. Connects bioengineering and cancer biology, providing information on sensors, imaging, therapies and in-vitro models Presents the most comprehensive coverage in the field of cancer engineering to date Provides an academic introduction to (molecular) bioengineering for students, regardless of scientific background (math's, physics, chemistry, biology) Highlights the unmet medical needs for bioengineers and the main technological breakthroughs to cancer biologists

Targeted Cancer Imaging

Mehdi Azizi,Hadi Kokabi,Hassan Dianat-Moghadam,Mohammad Mehrmohammadi
Targeted Cancer Imaging Book PDF

Author : Mehdi Azizi,Hadi Kokabi,Hassan Dianat-Moghadam,Mohammad Mehrmohammadi
Publisher : Academic Press
Page : 218 pages
File Size : 48,8 Mb
Release : 2021-11-24
Category : Medical
ISBN : 9780128245149

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Targeted Cancer Imaging by Mehdi Azizi,Hadi Kokabi,Hassan Dianat-Moghadam,Mohammad Mehrmohammadi Pdf

Targeted Cancer Imaging: Design and Synthesis of Nanoplatforms based on Tumour Biology reviews and categorizes imaging and targeting approaches according to cancer type, highlighting new and safe approaches that involve membrane-coated nanoparticles, tumor cell-derived extracellular vesicles, circulating tumor cells, cell-free DNAs, and cancer stem cells, all with the goal of pointing the way to developing precise targeting and multifunctional nanotechnology-based imaging probes in the future. This book is highly multidisciplinary, bridging the knowledge gap between tumor biology, nanotechnology, and diagnostic imaging, and thus making it suitable for researchers ranging from oncology to bioengineering. Although considerable efforts have been conducted to diagnose, improve and treat cancer in the past few decades, existing therapeutic options are insufficient, as mortality and morbidity rates remain high. One of the best hopes for substantial improvement lies in early detection. Recent advances in nanotechnology are expected to increase our current understanding of tumor biology, allowing nanomaterials to be used for targeting and imaging both in vitro and in vivo experimental models. Gives understanding of cancer biology that is appropriate for students and researchers in engineering and nanotechnology Demonstrates cancer targeting strategies of multifunctional nanotechnology-based imaging probes Shows how to design, synthesize and apply cancer imaging nanostructures

Targeted Cancer Immune Therapy

Joseph Lustgarten,Yan Cui,Shulin Li
Targeted Cancer Immune Therapy Book PDF

Author : Joseph Lustgarten,Yan Cui,Shulin Li
Publisher : Springer Science & Business Media
Page : 340 pages
File Size : 43,7 Mb
Release : 2009-10-09
Category : Medical
ISBN : 9781441901705

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Targeted Cancer Immune Therapy by Joseph Lustgarten,Yan Cui,Shulin Li Pdf

Stimulation of the immune system’s ability to control and destroy tumors cont- ues to be the goal of cancer immune therapy; but the scope has rapidly expanded; approaches are constantly updated; new molecules are continually introduced; and immune mechanisms are becoming better understood. This book has no intention of covering every aspect of immune therapy but rather focuses on the novelty of cancer immune therapy in an attempt to give readers an opportunity to absorb the new aspects of immune therapy from a single source. In this regard, three areas were selected: cytokine immune therapy, cell-based immune therapy, and targeted immune therapy. In each of these three sections, only the novel aspects of immune therapy were described instead of attempting to cover any historical achievement. In the first section, Cytokine Immune Therapy, the IL12 family, IL18, IL21, IL24, IL28, and IL29 were emphasized in regard to the an- tumor function and application in treating tumors. Most of these selected cyt- ines were discovered in last 10 years. In the second section, Cell-based Immune Therapy, the focus was engineering potent immune regulatory or effector cells such as dendritic cells, T cells, and stem cells. Cell engineering design is primarily based on the increased understanding of the interaction of tumor antigen-presenting cells, antigen- specific effector cells, and the tumor microenvironment.

Precision Medicine in Cancer Therapy

Daniel D. Von Hoff,Haiyong Han
Precision Medicine in Cancer Therapy Book PDF

Author : Daniel D. Von Hoff,Haiyong Han
Publisher : Springer
Page : 283 pages
File Size : 41,6 Mb
Release : 2019-06-17
Category : Medical
ISBN : 9783030163914

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Precision Medicine in Cancer Therapy by Daniel D. Von Hoff,Haiyong Han Pdf

This book presents the latest advances in precision medicine in some of the most common cancer types, including hematological, lung and breast malignancies. It also discusses emerging technologies that are making a significant impact on precision medicine in cancer therapy. In addition to describing specific approaches that have already entered clinical practice, the book explores new concepts and tools that are being developed. Precision medicine aims to deliver personalized healthcare tailored to a patient’s genetics, lifestyle and environment, and cancer therapy is one of the areas in which it has flourished in recent years. Documenting the latest advances, this book is of interest to physicians and clinical fellows in the front line of the war on cancer, as well as to basic scientists working in the fields of cancer biology, drug development, biomarker discovery, and biomedical engineering. The contributing authors include translational physicians with first-hand experience in precision patient care.

Bioengineering and Cancer Stem Cell Concept

Mirjana Pavlovic,Bela Balint
Bioengineering and Cancer Stem Cell Concept Book PDF

Author : Mirjana Pavlovic,Bela Balint
Publisher : Springer
Page : 144 pages
File Size : 50,7 Mb
Release : 2015-12-22
Category : Computers
ISBN : 9783319256702

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Bioengineering and Cancer Stem Cell Concept by Mirjana Pavlovic,Bela Balint Pdf

This book explores the role of cancer stem cells in the diagnosis, treatment, and cure of cancers. This book also tackles novel methodology for cancer stem cell marker identification, cancer stem cell respiration and metabolism, genetic and epigenetic mechanisms including DNA methylation, and mi-RNA assemble. It also emphasizes the role of Bioinformatics techniques, which provide a novel methodology for modeling cancer outcomes. The authors investigate the difference between cancer stem cells and normal stem cells, along with the concept of targeted cancer stem cell therapy. Although the theoretical explanations of cancer stem cell involvement in leukemia and solid cancers are controversial, there is now little doubt that cancer stem cells exist within otherwise heterogeneous cancer cell population. The brief examines the two leading theories, hierarchical and the stochastic/cancer stem cell model. Researchers, professors and advanced-level students focused on bioengineering and computer science will find this book to be a valuable resource. It is a very good source of critical references for understanding of this problem, and a useful tool for professionals in related fields.

Bio-Nanomedicine for Cancer Therapy

Flavia Fontana,Hélder A. Santos
Bio Nanomedicine for Cancer Therapy Book PDF

Author : Flavia Fontana,Hélder A. Santos
Publisher : Springer Nature
Page : 358 pages
File Size : 55,5 Mb
Release : 2021-02-04
Category : Medical
ISBN : 9783030581749

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Bio-Nanomedicine for Cancer Therapy by Flavia Fontana,Hélder A. Santos Pdf

The book covers the latest developments in biologically-inspired and derived nanomedicine for cancer therapy. The purpose of the book is to illustrate the significance of naturally-mimicking systems for enhancing the dose delivered to the tumor, to improve stability, and prolong the circulation time. Moreover, readers are presented with advanced materials such as adjuvants for immunostimulation in cancer vaccines. The book also provides a comprehensive overview of the current status of academic research. This is an ideal book for students, researchers, and professors working in nanotechnology, cancer, targeted drug delivery, controlled drug release, materials science, and biomaterials as well as companies developing cancer immunotherapy.

Cancer Nanotechnology

Stephen R. Grobmyer,Brij M. Moudgil
Cancer Nanotechnology Book PDF

Author : Stephen R. Grobmyer,Brij M. Moudgil
Publisher : Humana Press
Page : 366 pages
File Size : 45,6 Mb
Release : 2011-08-25
Category : Medical
ISBN : 1607616130

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Cancer Nanotechnology by Stephen R. Grobmyer,Brij M. Moudgil Pdf

Early detection of cancer at the cellular level, even before anatomic anomalies are visible, is critical to more efficacious and cost effective diagnosis and therapeutic advances. In Cancer Nanotechnology: Methods and Protocols, an international panel of experts provide the most recent, cutting-edge, "how-to" approaches developed and employed by researchers in a variety of disciplines to identify cancer specific biomarkers, construct suitable multifunctional targeted nanostructure platforms, along with enhanced imaging and therapeutic applications. Covering such topics as multifunctional and multimodal nanoparticles, nanoparticle mediated cancer theranostics, molecular targets for cancer nanotechnology, and nanoparticles for non-invasive image-guided cancer therapy, the volume addresses the key challenges of the field today, specifically targeted and localized delivery of the drugs. As a volume in the highly successful Methods in Molecular BiologyTM series, the protocols chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Nanotechnology: Methods and Protocols integrates cancer biology, clinical oncology, molecular cancer imaging, materials science and chemical engineering, biomedical engineering, toxicology, computer science, electrical engineering, chemistry, physics, and mathematics in order to achieve the vital goals of nanotechnology-mediated early cancer detection and more efficacious and less toxic therapies for these devastating diseases.

Biomaterials for Cancer Therapeutics

Kinam Park
Biomaterials for Cancer Therapeutics Book PDF

Author : Kinam Park
Publisher : Woodhead Publishing
Page : 783 pages
File Size : 48,6 Mb
Release : 2020-03-05
Category : Technology & Engineering
ISBN : 9780081029848

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Biomaterials for Cancer Therapeutics by Kinam Park Pdf

Biomaterials for Cancer Therapeutics: Evolution and Innovation, Second Edition, discusses the role and potential of biomaterials in treating this prevalent disease. The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Part Two discusses synthetic vaccines, proteins and polymers for cancer therapeutics. Part Three focuses on theranosis and drug delivery systems, while the final set of chapters look at biomaterial therapies and cancer cell interaction. Cancer affects people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is being developed to target, treat and prevent cancer. Hence, this book is a welcomed resource to the discussion. Provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, treatment and prevention of cancer Discusses how the properties of specific biomaterials make them important in cancer treatment Covers synthetic vaccines, proteins and polymers for cancer therapeutics

Targeted Therapy in Translational Cancer Research

Apostolia-Maria Tsimberidou,Razelle Kurzrock,Kenneth C. Anderson
Targeted Therapy in Translational Cancer Research Book PDF

Author : Apostolia-Maria Tsimberidou,Razelle Kurzrock,Kenneth C. Anderson
Publisher : John Wiley & Sons
Page : 320 pages
File Size : 44,6 Mb
Release : 2015-10-08
Category : Medical
ISBN : 9781118468685

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Targeted Therapy in Translational Cancer Research by Apostolia-Maria Tsimberidou,Razelle Kurzrock,Kenneth C. Anderson Pdf

Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancer Covers basic principles of targeted therapy, including immunotherapy and the roles of cancer stem cells, the microenvironment, angiogenesis, epigenetics, microRNAs, and functional imaging in precision medicine Summarises major advances in therapeutic management of hematologic malignancies and solid tumors using conventional therapy, targeted therapy, immunotherapy, or novel treatment modalities

Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy

Anubhab Mukherjee,Vijay Sagar Madamsetty,Sudip Mukherjee
Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy Book PDF

Author : Anubhab Mukherjee,Vijay Sagar Madamsetty,Sudip Mukherjee
Publisher : Morgan & Claypool Publishers
Page : 100 pages
File Size : 47,8 Mb
Release : 2021-04-06
Category : Technology & Engineering
ISBN : 9781636391052

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Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy by Anubhab Mukherjee,Vijay Sagar Madamsetty,Sudip Mukherjee Pdf

Recently, immunomodulatory nanomaterials have gained immense attention due to their involvement in the modulation of the body’s immune response to cancer therapy. This book highlights various immunomodulatory nanomaterials (including organic, polymer, inorganic, liposomes, viral, and protein nanoparticles) and their role in cancer therapy. Additionally, the mechanism of immunomodulation is reviewed in detail. Finally, the challenges of these therapies and their future outlook are discussed. We believe this book will be helpful to a broad community including students, researchers, educators, and industrialists.

Biomaterials for Cancer Therapeutics

Kinam Park
Biomaterials for Cancer Therapeutics Book PDF

Author : Kinam Park
Publisher : Elsevier
Page : 543 pages
File Size : 54,9 Mb
Release : 2013-11-23
Category : Technology & Engineering
ISBN : 9780857096760

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Biomaterials for Cancer Therapeutics by Kinam Park Pdf

Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease.The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins and polymers for cancer therapeutics. Part three focusses on theranosis and drug delivery systems, whilst the final set of chapters look at biomaterial therapies and cancer cell interaction.This extensive book provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer. Biomaterials for cancer therapeutics is an essential text for academics, scientists and researchers within the biomedical industry, and will also be of interest to clinicians with a research interest in cancer therapies and biomaterials. A complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer Discusses the fundamentals of biomaterials for cancer therapeutics Discusses synthetic vaccines, proteins and polymers for cancer therapeutics

Advances in Nanotheranostics II

Zhifei Dai
Advances in Nanotheranostics II Book PDF

Author : Zhifei Dai
Publisher : Springer
Page : 381 pages
File Size : 49,6 Mb
Release : 2016-01-11
Category : Technology & Engineering
ISBN : 9789811000638

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Advances in Nanotheranostics II by Zhifei Dai Pdf

This book surveys recent advances in theranostics based on magnetic nanoparticles, ultrasound contrast agents, silica nanoparticles and polymeric micelles. It presents magnetic nanoparticles, which offer a robust tool for contrast enhanced MRI imaging, magnetic targeting, controlled drug delivery, molecular imaging guided gene therapy, magnetic hyperthermia, and controlling cell fate. Multifunctional ultrasound contrast agents have great potential in ultrasound molecular imaging, multimodal imaging, drug/gene delivery, and integrated diagnostics and therapeutics. Due to their diversity and multifunctionality, polymeric micelles and silica-based nanocomposites are highly capable of enhancing the efficacy of multimodal imaging and synergistic cancer therapy. This comprehensive book summarizes the main advances in multifunctional nanoprobes for targeted imaging and therapy of gastric cancer, and explores the clinical translational prospects and challenges. Although more research is needed to overcome the substantial obstacles that impede the development and availability of nanotheranostic products, such nontrivial nanoagents are expected to revolutionize medical treatments and help to realize the potential of personalized medicine to diagnose, treat, and follow-up patients with cancer. Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.

Advanced Targeted Nanomedicine

Uche Chude-Okonkwo,Reza Malekian,BT Maharaj
Advanced Targeted Nanomedicine Book PDF

Author : Uche Chude-Okonkwo,Reza Malekian,BT Maharaj
Publisher : Springer
Page : 143 pages
File Size : 55,9 Mb
Release : 2019-01-11
Category : Technology & Engineering
ISBN : 9783030110031

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Advanced Targeted Nanomedicine by Uche Chude-Okonkwo,Reza Malekian,BT Maharaj Pdf

This book presents medical challenges as communication engineering problems. It offers the reader the interesting perspective of exploring and understanding disease pathology from the point of view of communication engineers. Therefore, diseases and their treatments can be addressed using conventional communication paradigms, approaches, tools and devices; thereby ushering in the interdisciplinary research platform termed advanced targeted nanomedicine. The rudimentary framework for advanced targeted nanomedicine is presented and expatiated across the seven chapters of this book.