The Communicative Cardiac Cell

Author : Samuel Sideman,Rafael Beyar,Amir Landesberg
Publisher : Wiley-Blackwell
Page : 452 pages
File Size : 52,9 Mb
Release : 2005-06-24
Category : Science
ISBN : 1573315486

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The Communicative Cardiac Cell by Samuel Sideman,Rafael Beyar,Amir Landesberg Pdf

The basic phenomena of intra- and intercellular communication and the transport signals within and between the cells controlling cardiac function are described and discussed in this volume. The amazing synchronization of millions of cells and billions of nanoscale molecular motors, ion gates, and ion pumps assure normal cardiac function; whereas disharmony and local transport and signal disruptions are the forecasters, and eventual causes, of pathologic conditions and heart failure. Although this volume concentrates on basic phenomena, strong emphasis is given to the related clinical and pharmaceutical manifestations, and chapters have been contributed by molecular biologists, pharmaceutical experts, and cardiac scientists. This volume will promote better understanding and, consequently, better clinical and pharmaceutical handling of the various aspects of cardiac pathophysiologies associated with electrical, mechanical, and metabolic and circulatory disorders in the cardiovascular system. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Author : S. Sideman,Rafael Beyar,Amir Landesberg
Publisher : Unknown
Page : 460 pages
File Size : 48,6 Mb
Release : 2005
Category : Science
ISBN : UVA:X004925329

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The Communicative Cardiac Cell by S. Sideman,Rafael Beyar,Amir Landesberg Pdf

The basic phenomena of intra- and intercellular communication and the transport signals within and between the cells controlling cardiac function are described and discussed in this volume. Although it concentrates on basic phenomena, strong emphasis is given to the related clinical and pharmaceutical manifestations.

Author : Walmor C. de Mello,Michiel J. Janse
Publisher : Springer Science & Business Media
Page : 322 pages
File Size : 44,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461555254

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Heart Cell Communication in Health and Disease by Walmor C. de Mello,Michiel J. Janse Pdf

In Heart Cell Communication in Health and Disease an extensive review of different aspects of heart cell communication is presented. The book starts with the fundamental concept that cardiac cells are communicated, and then proceeds to the role of gap junctions in heart development, the molecular biology of gap junctions, the biophysics of the intercellular channels, the control of junctional conductance and the influence of gap junctions on impulse propagation. This is the first time that a single volume has described cell communication in the normal heart and under different pathological conditions such as heart failure, coronary disease, myocardial ischemia and cardiac arrhythmias. In this way the process of cell communication is analyzed at different levels of complexity, providing the reader with a wide view of this field and its relevance to cardiology.

Author : Anonim
Publisher : Academic Press
Page : 648 pages
File Size : 46,6 Mb
Release : 1999-12-22
Category : Science
ISBN : 0080585205

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Gap Junctions: Molecular Basis of Cell Communication in Health and Disease by Anonim Pdf

Since the first gap junction protein (connexin) was cloned over a decade ago, more than a dozen connexin genes have been cloned. Consequently, a wealth of information on the molecular basis of gap junctional communication has been accumulated. This book pays tribute to this exciting era in the history of cell communication research by documenting the great strides made in this field as a result of the merging of biophysics and molecular biology, two of the most powerful approaches to studying the molecular basis of membrane channel behavior. Twenty-eight comprehensive chapters, authored by internationally recognized leaders in the field, discuss the biophysical, physiological, and molecular characteristics of cell-to-cell communication via gap junctions. Key aspects of molecular structure, formation, gating, conductance, and permeability of vertebrate and invertebrate gap junction channels are highlighted. In addition, a number of chapters focus on recent discoveries that implicate connexin mutations and alterations of gap junctional communication in the pathogenesis of several diseases, including the X-linked Charcot Marie Tooth demyelinating disease, some forms of inherited sensorineural deafness, malignant transformation, cardiac malformations and arrhythmia, eye lens cataract, and Chagas' disease.

Author : Walmor C. De Mello
Publisher : Springer Science & Business Media
Page : 383 pages
File Size : 50,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461319177

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Cell-to-Cell Communication by Walmor C. De Mello Pdf

Author : Walmor C. de Mello,Michiel J. Janse
Publisher : Springer
Page : 295 pages
File Size : 50,7 Mb
Release : 2011-09-15
Category : Medical
ISBN : 1461555264

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Heart Cell Communication in Health and Disease by Walmor C. de Mello,Michiel J. Janse Pdf

In Heart Cell Communication in Health and Disease an extensive review of different aspects of heart cell communication is presented. The book starts with the fundamental concept that cardiac cells are communicated, and then proceeds to the role of gap junctions in heart development, the molecular biology of gap junctions, the biophysics of the intercellular channels, the control of junctional conductance and the influence of gap junctions on impulse propagation. This is the first time that a single volume has described cell communication in the normal heart and under different pathological conditions such as heart failure, coronary disease, myocardial ischemia and cardiac arrhythmias. In this way the process of cell communication is analyzed at different levels of complexity, providing the reader with a wide view of this field and its relevance to cardiology.

Author : Marcella Canton,Martina Calore,Libero Vitiello
Publisher : Frontiers Media SA
Page : 191 pages
File Size : 40,7 Mb
Release : 2021-11-30
Category : Science
ISBN : 9782889717262

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Pathogenic Mechanisms in Cardiac and Skeletal Muscle Diseases by Marcella Canton,Martina Calore,Libero Vitiello Pdf

Author : Walmor C. de Mello,M.J. Janse
Publisher : Springer Science & Business Media
Page : 475 pages
File Size : 45,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461511557

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Heart Cell Coupling and Impulse Propagation in Health and Disease by Walmor C. de Mello,M.J. Janse Pdf

Heart Cell Coupling and Impulse Propagation in Health and Disease includes an up-to-date review on how heart cells communicate and impulse propagation under normal as well as under pathological conditions. The complexity of intercellular coupling and impulse propagation is discussed, providing the reader with a broad view of the importance of these processes and how they contribute to the generation of cardiac arrhythmias and heart failure. The different aspects and intricacies of heart cell communication is discussed by different authors, each one an expert in their own field. The present publication will be of interest to cardiologists, electrophysiologists, heart physiologists, cardiac pharmacologists, biophysicists, and cell or molecular biologists.

Author : Elissavet Kardami,Larry Hryshko,Nasrin Mesaeli
Publisher : Springer Science & Business Media
Page : 184 pages
File Size : 51,7 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781475747126

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Cardiac Cell Biology by Elissavet Kardami,Larry Hryshko,Nasrin Mesaeli Pdf

Cardiac cell biology has come of age. Recognition of activated or modified signaling molecules by specific antibodies, new selective inhibitors, and fluorescent fusion tags are but a few of the tools used to dissect signaling pathways and cross-talk mechanisms that may eventually allow rational drug design. Understanding the regulation of cardiac hypertrophy in all its complexity remains a fundamental goal of cardiac research. Since the advancement of adenovirally mediated gene transfer, transfection efficiency is no longer a limiting factor in the study of cardiomyocytes. A limiting factor in considering cell transplantion as a strategy to repair the damaged heart is cell availability at the right time. Cardiac gap junctions, intercellular communication channels that allow electrical and metabolic coupling and play an important role in arrhythmogenesis are now understood to be exquisite sensors of cardiac change. The reports in this volume incLude elegant studies that made use of cutting edge technological advances and many specialized reagents to address these issues.

Author : Anonim
Publisher : Unknown
Page : 760 pages
File Size : 46,6 Mb
Release : 2003
Category : American literature
ISBN : UOM:39015066043244

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American Book Publishing Record by Anonim Pdf

Author : Yoshinobu Kanno
Publisher : Elsevier Science & Technology
Page : 486 pages
File Size : 45,8 Mb
Release : 1995
Category : Medical
ISBN : UOM:39015033981922

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Intercellular Communication Through Gap Junctions by Yoshinobu Kanno Pdf

This volume focuses on the biological meaning of intercellular communication through gap junctions in various organs. The most recent up-to-date findings have been included.

Author : J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young
Publisher : Unknown
Page : 0 pages
File Size : 42,9 Mb
Release : 2013-04-25
Category : Electronic
ISBN : 1947172808

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Anatomy and Physiology by J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young Pdf

Author : Michitoshi Inoue,Masatsugu Hori,Shoichi Imai,Robert M. Berne
Publisher : Springer Science & Business Media
Page : 330 pages
File Size : 46,9 Mb
Release : 2013-11-09
Category : Medical
ISBN : 9784431683674

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Regulation of Coronary Blood Flow by Michitoshi Inoue,Masatsugu Hori,Shoichi Imai,Robert M. Berne Pdf

Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.

Author : Samuel Sideman,Rafael Beyar,Amir Landesberg
Publisher : Wiley-Blackwell
Page : 292 pages
File Size : 53,6 Mb
Release : 2008-04-14
Category : Medical
ISBN : STANFORD:36105131948254

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Control and Regulation of Transport Phenomena in the Cardiac System, Volume 1123 by Samuel Sideman,Rafael Beyar,Amir Landesberg Pdf

Leading researchers in the life sciences and engineers involved in research of transport phenomena in biological systems have contributed chapters that identify, analyze, and modify the control and regulation mechanisms of transport phenomena in biological systems, with particular emphasis on the cardiac system. Included in the contributions to this volume are the following topics: signaling mechanisms and transport phenomena; blood-tissue exchange and inter-tissue transport; cellular membrane transport and endocytosis of ions and metabolites; intracellular transport, energetics, and molecular motors; system biology, uni- and multi-scale transport models, and hierarchical analysis; and clinical considerations -- cardiac protection, metabolic and pharmaceutical augmentation, and interferences. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member.

Author : Pawan K. Singal,Ian M.C. Dixon,Naranjan S. Dhalla,Lorrie A. Kirshenbaum
Publisher : Springer Science & Business Media
Page : 570 pages
File Size : 44,9 Mb
Release : 2003-02-28
Category : Medical
ISBN : 1402071779

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Cardiac Remodeling and Failure by Pawan K. Singal,Ian M.C. Dixon,Naranjan S. Dhalla,Lorrie A. Kirshenbaum Pdf

The importance of the developmental approach for experimental and clinical cardiology is indisputable. Clinical-epidemiological studies have clearly shown that the risk factors of serious cardiovascular diseases, such as atherosclerosis and ischemic heart disease, are already present during the early phases of ontogenetic development. Furthermore, congenital cardiovascular malformations remain the single largest cause of infant mortality from congenital defects in industrial countries. It is therefore not surprising that the interest of theoretical and clinical cardiologists in the developmental approach keeps increasing. Advances in molecular biology accelerated this trend substantially. This book is based on contributions presented at the international symposium The Developing Heart in Prague in May 2000. It is our contention that the biological, electrophysiological, morphological, functional, biochemical and functional approaches employed by distinguished scientists worldwide will provide the reader with a global picture for changes characterizing the developing heart. It should stimulate the curiosity of cardiovascular scientists in gaining insight into the mechanisms of normal and pathological development.