The Iacuc Handbook Third Edition

Author : Jerald Silverman,Mark A. Suckow,Sreekant Murthy
Publisher : CRC Press
Page : 832 pages
File Size : 41,6 Mb
Release : 2014-05-20
Category : Medical
ISBN : 9781466555648

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The IACUC Handbook, Third Edition by Jerald Silverman,Mark A. Suckow,Sreekant Murthy Pdf

Ever since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States. As biomedical research continuously grows, the role and impact of the IACUC has increased in scope and complexity. The IACUC Handbook has become "the Bible" for individuals when the time comes for them to serve on their institution’s IACUC. It provides a foundation for understanding and implementing the many and varied responsibilities of this committee. This Third Edition comprehensively addresses the significant changes in the pertinent regulatory environment and interpretation of applicable federal laws, regulations, and policies. It provides multiple references and commentary on the new edition of the Guide for the Care and Use of Laboratory Animals, the new AVMA Guidelines for the Euthanasia of Animals: 2013 Edition, and the Office of Laboratory Animal Welfare’s Frequently Asked Questions. The Third Edition also features an updated survey of IACUC practices from institutions around the United States, offering wisdom gained from their experience. In addition, it includes a chapter that provides an international perspective on how animal welfare reviews can function in other countries.

Author : Jerald Silverman,Mark A. Suckow,Sreekant Murthy
Publisher : CRC Press
Page : 590 pages
File Size : 45,8 Mb
Release : 2000-04-20
Category : Medical
ISBN : 1420039768

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The IACUC Handbook by Jerald Silverman,Mark A. Suckow,Sreekant Murthy Pdf

Ever since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee has evolved as the premier instrument of animal welfare oversight within research institutions in the U.S. Its mission, in part, is to ensure that investigators, research technicians, animal care personnel and others are adequately trained to conduct research with animals in a proper and humane manner. But equally important is that the IACUC itself be adequately trained with regard to the successful interpretation and implementation of regulations and guidelines for proper animal care and use. The IACUC Handbook focuses on both basic and advanced concerns of those who participate in activities of Institutional Animal Care and Use Committees. Exhaustive in its content and written by leading authorities in the field, this handbook addresses those questions and problems that often confront IACUCs, and gives accurate, succinct answers. Information is provided in "Question and Answer" format, with the authors offering their personal opinions against a background of regulatory information. Under the "regulatory " heading, pertinent sections from such sources as the Animal Welfare Act and its regulations, the Health Research Extension Act of 1985, the Public Health Service Policy on Humane Care and Use of Laboratory Animals, the Guide for the Care and Use of Laboratory Animals, and others are included. The handbook also provides the personal opinions of chapter authors and results from informal surveys as examples of the approaches institutions have taken to solve complex issues. While not scientific, the surveys provide the reader with additional opinions. With the role and impact of the Institutional Animal Care and Use Committee expected to grow in scope and complexity, The IACUC Handbook provides a foundation for those attempting to understand and implement the many and varied responsibilities of this committee.

Author : Michael J. Derelanko,Carol S. Auletta
Publisher : CRC Press
Page : 1027 pages
File Size : 47,7 Mb
Release : 2014-03-07
Category : Law
ISBN : 9781439890134

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Handbook of Toxicology, Third Edition by Michael J. Derelanko,Carol S. Auletta Pdf

The Handbook of Toxicology, Third Edition provides an updated practical reference source for practicing toxicologists in the pharmaceutical and chemical industries, contract laboratories, regulatory agencies, and academia. Written by experts in their specific toxicology fields, the chapters provide both fundamental and applied information. Topics range from General Toxicology, to Genetic Toxicology, Human Clinical Toxicology, Histopathology, Clinical Pathology, Metabolism and Toxicokinetics, Risk Assessment, and more. New to this edition: Completely rewritten chapters covering immunotoxicology, endocrine toxicology, and reproductive and developmental toxicology, providing a fresh perspective on these topics Addition of new chapters on Chemical Toxicology, Pharmaceutical Toxicology, Juvenile Toxicology, and Safety Pharmacology Updated information dealing with Inhalation Toxicology, Neurotoxicology, and Regulatory Toxicology, which has been consolidated into single chapters for each specialty A separate glossary with toxicological terms presented both alphabetically and by toxicological subspecialty For nearly 20 years, this handbook has remained the only reference book of its kind, designed to facilitate easy access to information related to the various toxicology specialties. This updated edition of a popular reference book reflects current practices and the state of the science of toxicology.

Author : Jerald Silverman,Mark A. Suckow,Sreekant Murthy
Publisher : CRC Press
Page : 682 pages
File Size : 54,7 Mb
Release : 2006-10-04
Category : Medical
ISBN : 9781466565470

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The IACUC Handbook, Second Edition by Jerald Silverman,Mark A. Suckow,Sreekant Murthy Pdf

Since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States. By addressing questions and problems that often confront institutions, The IACUC Handbook, Second Edition provides accurate, succinct answers. It features comprehensive updates for all pertinent federal laws, regulations, and policies. It also contains an expanded survey of IACUC practices from institutions around the nation. With accessible information, this new editionprovides a foundation for those attempting to understand and implement the many and varied responsibilities of these committees.

Author : Melissa Dyson,Paulin Jirkof,Jennie Lofgren,Elizabeth Nunamaker,Daniel Pang
Publisher : Academic Press
Page : 790 pages
File Size : 42,8 Mb
Release : 2023-05-17
Category : Medical
ISBN : 9780128222201

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Anesthesia and Analgesia in Laboratory Animals by Melissa Dyson,Paulin Jirkof,Jennie Lofgren,Elizabeth Nunamaker,Daniel Pang Pdf

Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic and postoperative care requirements associated with experimental interventions. Fully revised and updated, this new edition provides the reader with agents, methods and techniques for anesthesia and analgesia that ensure humane, reproducible, and successful procedural outcomes. Sections cover ethical, regulatory and scientific considerations, principles of anesthesia and analgesia, anesthetic equipment and monitoring, periprocedural care, including dedicated chapters to the assessment and management of pain in laboratory species, and practical considerations by species, including relevant anatomy, physiology, and behavior of a broad range of lab animal species. This will be a complete reference for veterinarians involved in lab animal research as well as senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research. Provides researchers with the most comprehensive and up-to-date review of the use of anesthesia and analgesia in laboratory animals Includes complete coverage of agents' impact in research outcomes Thoroughly updated with new material on ferrets, birds, reptiles, amphibians, fish and cephalopods Covers hot topic areas such as pain research, ethical issues, legal issues and imaging studies

Author : Mark A. Suckow,Kay Stewart
Publisher : Academic Press
Page : 286 pages
File Size : 48,8 Mb
Release : 2016-11-16
Category : Medical
ISBN : 9780128023662

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Principles of Animal Research for Graduate and Undergraduate Students by Mark A. Suckow,Kay Stewart Pdf

Principles of Animal Research is the first publication to offer a broad look at animal research science for a student, early researcher, or technician. Offering guidance for all aspects of the research experience, including the research and development of a thesis, model selection, experimental design, IACUC protocol preparation, and animal husbandry and technical procedural needs, the book is a necessary addition to every student, technician, and researcher’s education. Provides background material for students to understand the broader backdrop against which animal research is undertaken Includes ethical and regulatory information Covers commonly used animal models and the process to choose a model for biomedical research

Author : William G. Greer,Ron E. Banks
Publisher : CRC Press
Page : 310 pages
File Size : 40,6 Mb
Release : 2016-02-22
Category : Medical
ISBN : 9781439849088

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The IACUC Administrator's Guide to Animal Program Management by William G. Greer,Ron E. Banks Pdf

The IACUC Administrator's Guide to Animal Program Management supports IACUC administrators who assist with developing, managing, and overseeing a program of animal care and animal use. It provides many options and possibilities for specific operational practices (e.g., how to build a well-functioning IACUC, what a functional protocol temp

Author : Brent J. Martin
Publisher : CRC Press
Page : 166 pages
File Size : 47,5 Mb
Release : 1997-11-25
Category : Medical
ISBN : 0849325676

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The Laboratory Cat by Brent J. Martin Pdf

This guide was created especially for individuals performing research with cats whose duties include animal facility management, animal husbandry, regulatory compliance, and technical procedures involved with their research. Basic information and common procedures are presented in detail.

Author : G.O. Evans
Publisher : CRC Press
Page : 230 pages
File Size : 45,6 Mb
Release : 1996-04-29
Category : Medical
ISBN : 9780748403509

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Animal Clinical Chemistry by G.O. Evans Pdf

By presenting background information on the selection and application of biochemical tests in safety assessment studies, this text seeks to provide a basis for improving the knowledge required to interpret data from toxicological studies. In addition to chapters which discuss the assessment of specific organ toxicity (such as the liver, kidney and thyroid), the book also covers pre-analytical variables, regulatory requirements and statistical approaches, and highlights some of the major differences between man and different laboratory animals. The editor and contributor are all members of the Animal Clinical Chemistry Association, a group formed to advance the science of animal clinical chemistry in safety evaluation, toxicology and veterinary science.

Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals
Publisher : National Academies Press
Page : 246 pages
File Size : 42,7 Mb
Release : 2011-01-27
Category : Science
ISBN : 9780309154000

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Guide for the Care and Use of Laboratory Animals by National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals Pdf

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Author : Brian R. Murphy,David W. Willis,American Fisheries Society
Publisher : Unknown
Page : 760 pages
File Size : 47,6 Mb
Release : 1996
Category : Technology & Engineering
ISBN : UOM:39015039055580

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Fisheries Techniques by Brian R. Murphy,David W. Willis,American Fisheries Society Pdf

Author : Robert H. Weichbrod,Gail A. (Heidbrink) Thompson,John N. Norton
Publisher : CRC Press
Page : 872 pages
File Size : 43,6 Mb
Release : 2017-09-07
Category : Medical
ISBN : 9781498748452

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Management of Animal Care and Use Programs in Research, Education, and Testing by Robert H. Weichbrod,Gail A. (Heidbrink) Thompson,John N. Norton Pdf

AAP Prose Award Finalist 2018/19 Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition is the extensively expanded revision of the popular Management of Laboratory Animal Care and Use Programs book published earlier this century. Following in the footsteps of the first edition, this revision serves as a first line management resource, providing for strong advocacy for advancing quality animal welfare and science worldwide, and continues as a valuable seminal reference for those engaged in all types of programs involving animal care and use. The new edition has more than doubled the number of chapters in the original volume to present a more comprehensive overview of the current breadth and depth of the field with applicability to an international audience. Readers are provided with the latest information and resource and reference material from authors who are noted experts in their field. The book: - Emphasizes the importance of developing a collaborative culture of care within an animal care and use program and provides information about how behavioral management through animal training can play an integral role in a veterinary health program - Provides a new section on Environment and Housing, containing chapters that focus on management considerations of housing and enrichment delineated by species - Expands coverage of regulatory oversight and compliance, assessment, and assurance issues and processes, including a greater discussion of globalization and harmonizing cultural and regulatory issues - Includes more in-depth treatment throughout the book of critical topics in program management, physical plant, animal health, and husbandry. Biomedical research using animals requires administrators and managers who are knowledgeable and highly skilled. They must adapt to the complexity of rapidly-changing technologies, balance research goals with a thorough understanding of regulatory requirements and guidelines, and know how to work with a multi-generational, multi-cultural workforce. This book is the ideal resource for these professionals. It also serves as an indispensable resource text for certification exams and credentialing boards for a multitude of professional societies Co-publishers on the second edition are: ACLAM (American College of Laboratory Animal Medicine); ECLAM (European College of Laboratory Animal Medicine); IACLAM (International Colleges of Laboratory Animal Medicine); JCLAM (Japanese College of Laboratory Animal Medicine); KCLAM (Korean College of Laboratory Animal Medicine); CALAS (Canadian Association of Laboratory Animal Medicine); LAMA (Laboratory Animal Management Association); and IAT (Institute of Animal Technology).

Author : Jann Hau,Steven J. Schapiro
Publisher : CRC Press
Page : 569 pages
File Size : 50,6 Mb
Release : 2002-10-28
Category : Medical
ISBN : 9781420040913

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Handbook of Laboratory Animal Science by Jann Hau,Steven J. Schapiro Pdf

The second edition of an international bestseller, this book provides veterinary specialists as well as veterinary and biomedical researchers with detailed information about laboratory animal genetics, diseases, health monitoring, nutrition, and environmental impact on animal experiments. Completely revised and updated, Volume I now contains expand

Author : C. Terrance Hawk,Steven Leary,Timothy Morris
Publisher : Wiley-Blackwell
Page : 203 pages
File Size : 40,6 Mb
Release : 2005-01-24
Category : Medical
ISBN : 0813810485

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Formulary for Laboratory Animals by C. Terrance Hawk,Steven Leary,Timothy Morris Pdf

Formulary for Laboratory Animals is an invaluable reference for treatment of laboratory animals and pocket pets. Drugs are listed alphabetically and categorized in five sections based on pharmacologic activity and animal species. This at-a-glance pocket reference is valuable for students and practitioners of veterinary medicine, researchers and laboratory technicians who prescribe or administer drugs used on common laboratory animals. The third edition includes a stronger international component, coverage of several new drugs, hundreds of additional dosages, and a thorough update throughout based on the most current research. The third edition also includes a chapter describing how to estimate drug dosages among species using allometric scaling methodology.

Author : Mark A. Suckow,Valerie Schroeder,Fred A. Douglas
Publisher : CRC Press
Page : 148 pages
File Size : 42,5 Mb
Release : 2010-04-12
Category : Medical
ISBN : 9781420091069

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The Laboratory Rabbit, Second Edition by Mark A. Suckow,Valerie Schroeder,Fred A. Douglas Pdf

With laboratory animals, especially rabbits, playing such an important role in biomedical research, the humane care of these animals is an ongoing concern. The Laboratory Rabbit, Second Edition presents basic information and common procedures in detail to provide a quick reference for caretakers, technicians, and researchers in a laboratory setting. Now in full color, the second edition of this book illustrates management practices and technical procedures with numerous figures and tables. It includes updated tables on anesthetic agents, methods of euthanasia, recommended needle sizes, injection sites, approximate values for injection, and sedative and immobilization agents. Plastic comb-bound for convenient and frequent use, this guide also provides sources and suppliers of additional information on rabbits, feed, and sanitation supplies.