The Trafficking And Metabolism Of Amyloid Precursor Protein Is Regulated By Its Cytoplasmic Carboxy Terminus And By Adaptor Protein Interactions

The Trafficking And Metabolism Of Amyloid Precursor Protein Is Regulated By Its Cytoplasmic Carboxy Terminus And By Adaptor Protein Interactions Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of The Trafficking And Metabolism Of Amyloid Precursor Protein Is Regulated By Its Cytoplasmic Carboxy Terminus And By Adaptor Protein Interactions book. This book definitely worth reading, it is an incredibly well-written.

Modular Protein Domains

Author : Giovanni Cesareni,Mario Gimona,Marius Sudol,Michael Yaffe
Publisher : John Wiley & Sons
Page : 524 pages
File Size : 41,8 Mb
Release : 2006-03-06
Category : Science
ISBN : 9783527605897

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Modular Protein Domains by Giovanni Cesareni,Mario Gimona,Marius Sudol,Michael Yaffe Pdf

Since the full functionality of any given protein can only be understood in terms of its interaction with other, often regulatory proteins, this unique reference source covers all relevant protein domains, including SH2, SH3, PDZ, WW, PTB, EH, PH and PX. Its user-oriented concept combines broad coverage with easy retrieval of essential information, and includes a special section on Web-based tools and databases covering protein modules and functional peptide motifs. Essential for the study of protein-protein interactions in vivo or in silico, and a prerequisite for successful functional proteomics studies. With a prologue by Sir Tom Blundell.

Dissertation Abstracts International

Author : Anonim
Publisher : Unknown
Page : 882 pages
File Size : 48,8 Mb
Release : 2004
Category : Dissertations, Academic
ISBN : UOM:39015062053981

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Dissertation Abstracts International by Anonim Pdf

Magnesium in the Central Nervous System

Author : Robert Vink,Mihai Nechifor
Publisher : University of Adelaide Press
Page : 354 pages
File Size : 53,5 Mb
Release : 2011
Category : Medical
ISBN : 9780987073051

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Magnesium in the Central Nervous System by Robert Vink,Mihai Nechifor Pdf

The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Cellular Mechanisms of Alzheimer's Disease

Author : C. Haass,G. Multhaup
Publisher : Karger Medical and Scientific Publishers
Page : 127 pages
File Size : 43,5 Mb
Release : 2006-01-01
Category : Medical
ISBN : 9783805581837

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Cellular Mechanisms of Alzheimer's Disease by C. Haass,G. Multhaup Pdf

This special topic issue of 'Neurodegenerative Diseases' contains contributions discussing the subject in-depth. 'Neurodegenerative Diseases' is a well-respected, international peer-reviewed journal in 'Neurobiology'. Special topic issues are included in the subscription.

Cumulated Index Medicus

Author : Anonim
Publisher : Unknown
Page : 1840 pages
File Size : 52,7 Mb
Release : 2000
Category : Medicine
ISBN : OSU:32436010864682

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Cumulated Index Medicus by Anonim Pdf

Neurodegenerative Diseases

Author : Uday Kishore
Publisher : BoD – Books on Demand
Page : 642 pages
File Size : 43,5 Mb
Release : 2013-05-15
Category : Medical
ISBN : 9789535110880

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Neurodegenerative Diseases by Uday Kishore Pdf

This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases and secretase, regulators, cholesterol, zinc, microglia, astrocytes, oligodendrocytes, etc, have been discussed in the context of disease progression. In addition, novel approaches to therapeutic interventions have also been presented. It is hoped that students, scientists and clinicians shall find this very informative book immensely useful and thought-provoking.

Society for Neuroscience Abstracts

Author : Society for Neuroscience. Meeting
Publisher : Unknown
Page : 1668 pages
File Size : 41,6 Mb
Release : 2001
Category : Electronic books
ISBN : NWU:35557000123370

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Society for Neuroscience Abstracts by Society for Neuroscience. Meeting Pdf

Index Medicus

Author : Anonim
Publisher : Unknown
Page : 2452 pages
File Size : 42,5 Mb
Release : 2004
Category : Medicine
ISBN : MINN:31951P00992553J

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Index Medicus by Anonim Pdf

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

The Transient Structure of the Amyloid Precursor Protein Cytoplasmic Tail and Phosphorylation Induced Structural Changes Detected by Solution Nuclear Magnetic Resonance Spectroscopy

Author : Theresa Ann Ramelot
Publisher : Unknown
Page : 318 pages
File Size : 53,7 Mb
Release : 2001
Category : Electronic
ISBN : CORNELL:31924089542116

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The Transient Structure of the Amyloid Precursor Protein Cytoplasmic Tail and Phosphorylation Induced Structural Changes Detected by Solution Nuclear Magnetic Resonance Spectroscopy by Theresa Ann Ramelot Pdf

Genomics, Circuits, and Pathways in Clinical Neuropsychiatry

Author : Thomas Lehner,Bruce L. Miller,Matthew W. State
Publisher : Academic Press
Page : 796 pages
File Size : 43,8 Mb
Release : 2016-06-07
Category : Science
ISBN : 9780128005309

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Genomics, Circuits, and Pathways in Clinical Neuropsychiatry by Thomas Lehner,Bruce L. Miller,Matthew W. State Pdf

This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics Identifies key concepts, methods, and findings Includes coverage of multiple disorders from autism to schizophrenia Reviews specific genes associated with disorders Discusses the genetic architecture of these syndromes Explains how recent findings are influencing the understanding of biology Clarifies the promise of these findings for future treatment

Journal of Cell Science

Author : Anonim
Publisher : Unknown
Page : 738 pages
File Size : 42,7 Mb
Release : 2000
Category : Cytology
ISBN : UOM:39015049079174

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Journal of Cell Science by Anonim Pdf

Neurobiology of Acupuncture

Author : Anonim
Publisher : Academic Press
Page : 363 pages
File Size : 48,7 Mb
Release : 2013-11-07
Category : Science
ISBN : 9780124115606

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Neurobiology of Acupuncture by Anonim Pdf

This book summarises the recent development in acupuncture research and in particular, the neurobiology of acupuncture. It provides a focus but a diverse range of subjects covering many body systems. The first a few chapters discuss the basic principles of acupuncture, then its modulatory effects on nervous system such as induction of neurotrophin and neurogenesis in the brain. Late chapters explore the clinical effects and potential mechanisms of acupuncture on different conditions ranging from neurological diseases such as Parkinson’s, Alzheimer’s, and stroke, to psychiatric illnesses, insomnia, hypertension, gastrointestinal diseases and drug addiction. We believe this will promote the understanding acupuncture treatment and enhance acupuncture research in the future. This volume of International Review of Neurobiology brings together cutting-edge research on the neurobiology of acupuncture It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery