Tissue Engineering Of Temporomandibular Joint Cartilage

Author : Kyriacos Athanasiou,Alejandro J. Almarza,Michael S. Detamore,Kerem N. Kalpakci
Publisher : Morgan & Claypool Publishers
Page : 122 pages
File Size : 45,9 Mb
Release : 2009-07-08
Category : Technology & Engineering
ISBN : 9781598299977

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Tissue Engineering of Temporomandibular Joint Cartilage by Kyriacos Athanasiou,Alejandro J. Almarza,Michael S. Detamore,Kerem N. Kalpakci Pdf

The temporomandibular joint (TMJ) is a site of intense morbidity for millions of people, especially young, pre-menopausal women. Central to TMJ afflictions are the cartilaginous tissues of the TMJ, especially those of the disc and condylar cartilage, which play crucial roles in normal function of this unusual joint. Damage or disease to these tissues significantly impacts a patient's quality of life by making common activities such as talking and eating difficult and painful. Unfortunately, these tissues have limited ability to heal, necessitating the development of treatments for repair or replacement. The burgeoning field of tissue engineering holds promise that replacement tissues can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical, biochemical, and anatomical characteristics of the disc and condylar cartilage, and also provides a historical perspective of past and current TMJ treatments and previous tissue engineering efforts. This book was written to serve as a reference for researchers seeking to learn about the TMJ, for undergraduate and graduate level courses, and as a compendium of TMJ tissue engineering design criteria. Table of Contents: The Temporomandibular Joint / Fibrocartilage of the TMJ Disc / Cartilage of the Mandibular Condyle / Tissue Engineering of the Disc / Tissue Engineering of the Mandibular Condyle / Current Perspectives

Author : Kyriacos Athanasiou,Alejandro J. Almarza,Michael S. Detamore,Kerem N. Kalpakci
Publisher : Springer Nature
Page : 114 pages
File Size : 49,5 Mb
Release : 2022-05-31
Category : Science
ISBN : 9783031025778

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Tissue Engineering of Temporomandibular Joint Cartilage by Kyriacos Athanasiou,Alejandro J. Almarza,Michael S. Detamore,Kerem N. Kalpakci Pdf

The temporomandibular joint (TMJ) is a site of intense morbidity for millions of people, especially young, pre-menopausal women. Central to TMJ afflictions are the cartilaginous tissues of the TMJ, especially those of the disc and condylar cartilage, which play crucial roles in normal function of this unusual joint. Damage or disease to these tissues significantly impacts a patient's quality of life by making common activities such as talking and eating difficult and painful. Unfortunately, these tissues have limited ability to heal, necessitating the development of treatments for repair or replacement. The burgeoning field of tissue engineering holds promise that replacement tissues can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical, biochemical, and anatomical characteristics of the disc and condylar cartilage, and also provides a historical perspective of past and current TMJ treatments and previous tissue engineering efforts. This book was written to serve as a reference for researchers seeking to learn about the TMJ, for undergraduate and graduate level courses, and as a compendium of TMJ tissue engineering design criteria. Table of Contents: The Temporomandibular Joint / Fibrocartilage of the TMJ Disc / Cartilage of the Mandibular Condyle / Tissue Engineering of the Disc / Tissue Engineering of the Mandibular Condyle / Current Perspectives

Author : Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu
Publisher : Morgan & Claypool Publishers
Page : 183 pages
File Size : 41,6 Mb
Release : 2010
Category : Medical
ISBN : 9781598298758

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Articular Cartilage Tissue Engineering by Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu Pdf

Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage's low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analysis on the United States Food and Drug Administration regulatory pathways that products must follow to market. This book was written to serve as a reference for researchers seeking to learn about articular cartilage, for undergraduate and graduate level courses, and as a compendium of articular cartilage tissue engineering design criteria. Table of Contents: Hyaline Articular Cartilage / Cartilage Aging and Pathology / In Vitro / Bioreactors / Future Directions

Author : Dimitrios D. Nikolopoulos,George K. Safos,Kalpaxis Dimitrios
Publisher : BoD – Books on Demand
Page : 160 pages
File Size : 51,8 Mb
Release : 2019-06-05
Category : Technology & Engineering
ISBN : 9781789238495

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Cartilage Tissue Engineering and Regeneration Techniques by Dimitrios D. Nikolopoulos,George K. Safos,Kalpaxis Dimitrios Pdf

Osteochondral defects can be challenging to treat, first, because the damaged articular cartilage has a poor intrinsic reparative capability, and second, because these defects cause chronic pain and serious disability. That is why cartilage repair remains one of the most challenging issues of musculoskeletal medicine. Arthroscopic and open techniques that have been developed over the last two decades intend to promote the success of complete repair of the articular cartilage defects; nevertheless, these therapies cannot always offer 100% success. Nowadays, cartilage tissue engineering is an emerging technique for the regeneration of cartilage tissue. Taking into consideration these perspectives, this book aims to present a summary of cartilage tissue engineering, including development, recent progress, and major steps taken toward the regeneration of functional cartilage tissue. Special emphasis is placed on the role of stimulating factors, including growth factors, gene therapies, as well as scaffolds, including natural, synthetic, and nanostructured.

Author : Gregory R. Bock,Jamie A. Goode
Publisher : John Wiley & Sons
Page : 272 pages
File Size : 47,6 Mb
Release : 2003-04-18
Category : Medical
ISBN : UOM:39015056838082

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Tissue Engineering of Cartilage and Bone by Gregory R. Bock,Jamie A. Goode Pdf

Papers from a symposium held at the Novartis Institute, London, 9-11 Apr. 2002.

Author : Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu,Grayson D. DuRaine,A. Hari Reddi
Publisher : CRC Press
Page : 594 pages
File Size : 55,6 Mb
Release : 2017-10-19
Category : Medical
ISBN : 9781351760140

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Articular Cartilage by Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu,Grayson D. DuRaine,A. Hari Reddi Pdf

This book covers the latest research and advancements related to articular cartilage in biology, development, pathology, clinical applications and tissue engineering. The authors take an interdisciplinary approach that encompasses the breadth and depth of basic science, bioengineering, translational science and detailed methological approaches. It is designed to be an all encompassing encyclopedia of articular cartilage. Written at a level that allows wide accessibility, the book’s comprehensive focus on multiple aspects of articular cartilage sets it apart from other books.

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Board on Health Sciences Policy,Committee on Temporomandibular Disorders (TMDs): From Research Discoveries to Clinical Treatment
Publisher : National Academies Press
Page : 427 pages
File Size : 50,5 Mb
Release : 2020-07-01
Category : Medical
ISBN : 9780309670487

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Temporomandibular Disorders by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Board on Health Sciences Policy,Committee on Temporomandibular Disorders (TMDs): From Research Discoveries to Clinical Treatment Pdf

Temporomandibular disorders (TMDs), are a set of more than 30 health disorders associated with both the temporomandibular joints and the muscles and tissues of the jaw. TMDs have a range of causes and often co-occur with a number of overlapping medical conditions, including headaches, fibromyalgia, back pain and irritable bowel syndrome. TMDs can be transient or long-lasting and may be associated with problems that range from an occasional click of the jaw to severe chronic pain involving the entire orofacial region. Everyday activities, including eating and talking, are often difficult for people with TMDs, and many of them suffer with severe chronic pain due to this condition. Common social activities that most people take for granted, such as smiling, laughing, and kissing, can become unbearable. This dysfunction and pain, and its associated suffering, take a terrible toll on affected individuals, their families, and their friends. Individuals with TMDs often feel stigmatized and invalidated in their experiences by their family, friends, and, often, the health care community. Misjudgments and a failure to understand the nature and depths of TMDs can have severe consequences - more pain and more suffering - for individuals, their families and our society. Temporomandibular Disorders: Priorities for Research and Care calls on a number of stakeholders - across medicine, dentistry, and other fields - to improve the health and well-being of individuals with a TMD. This report addresses the current state of knowledge regarding TMD research, education and training, safety and efficacy of clinical treatments of TMDs, and burden and costs associated with TMDs. The recommendations of Temporomandibular Disorders focus on the actions that many organizations and agencies should take to improve TMD research and care and improve the overall health and well-being of individuals with a TMD.

Author : Florencio Monje Gil
Publisher : Elsevier Health Sciences
Page : 145 pages
File Size : 48,8 Mb
Release : 2022-09-21
Category : Medical
ISBN : 9780323987424

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Temporomandibular Joint Surgery, An Issue of Atlas of the Oral & Maxillofacial Surgery Clinics, E-book by Florencio Monje Gil Pdf

In this issue of Atlas of the Oral and Maxillofacial Surgery Clinics, guest editor Dr. Florencio Monje Gil brings his considerable expertise to the topic of Temporomandibular Joint Surgery. TMJ disorders affect 12% or more of the population in the U.S. alone, primarily women in their childbearing years. In this issue, top experts in the field provide comprehensive, current tutorials of every major TMJ surgery, including articles on pre- and postoperative treatment. Contains 14 practice-oriented topics including rules for surgical decision making in temporomandibular joint treatment; temporomandibular joint arthrocentesis; operative arthroscopy and electrocoagulation of the temporomandibular joint; open temporomandibular joint surgery: discectomy with or without interpositional reconstruction; temporomandibular joint surgery: open discopexy; and more. Provides in-depth clinical reviews on temporomandibular joint surgery, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author : Kalpaxis Dimitrios,George K. Safos,Dimitrios D. Nikolopoulos
Publisher : Unknown
Page : 158 pages
File Size : 49,8 Mb
Release : 2019
Category : Medicine (General)
ISBN : 1838807810

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Cartilage Tissue Engineering and Regeneration Techniques by Kalpaxis Dimitrios,George K. Safos,Dimitrios D. Nikolopoulos Pdf

Osteochondral defects can be challenging to treat, first, because the damaged articular cartilage has a poor intrinsic reparative capability, and second, because these defects cause chronic pain and serious disability. That is why cartilage repair remains one of the most challenging issues of musculoskeletal medicine. Arthroscopic and open techniques that have been developed over the last two decades intend to promote the success of complete repair of the articular cartilage defects; nevertheless, these therapies cannot always offer 100% success. Nowadays, cartilage tissue engineering is an emerging technique for the regeneration of cartilage tissue. Taking into consideration these perspectives, this book aims to present a summary of cartilage tissue engineering, including development, recent progress, and major steps taken toward the regeneration of functional cartilage tissue. Special emphasis is placed on the role of stimulating factors, including growth factors, gene therapies, as well as scaffolds, including natural, synthetic, and nanostructured.

Author : Krishna Pramanik
Publisher : Unknown
Page : 0 pages
File Size : 54,5 Mb
Release : 2023-12
Category : Electronic
ISBN : 1032156899

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Stem Cell and Tissue Engineering by Krishna Pramanik Pdf

"This book covers conventional clinical treatment methods for handling bone, cartilage, and related disorders along with their limitations and highlights the current state of art of tissue engineering as an alternative for regenerating defective tissue. Potential biomimetic scaffolding materials and their desired properties, modifications, optimizations, and interactions are described. It reviews the design, development, characterization, properties, and biological functions of biomaterials, various bioreactor systems, and involved translational challenges. Features: Discusses the key aspects of generating engineered bone, cartilage, and associated tissues. Covers integration of stem cells and biomaterials including assessment of tissue graft, and translational strategy. Reviews multiple engineering principles involved in the various stages of developing biomaterials and scaffold. Explores key factors influencing tissue graft generation and challenges involved in various stages. Includes several exercises including review questions, numerical problems, for better understanding of the subject. This book is aimed at researchers, students, professionals in biomedical engineering, tissue engineering, biomaterials, and orthopaedics"--

Author : Robert Mauck,Dawn Elliott
Publisher : Morgan & Claypool
Page : 100 pages
File Size : 53,8 Mb
Release : 2009-10-15
Category : Technology & Engineering
ISBN : 1608451666

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Fibrocartilage Tissue Engineering by Robert Mauck,Dawn Elliott Pdf

Author : Samuel E. Lynch
Publisher : Unknown
Page : 320 pages
File Size : 54,6 Mb
Release : 2008
Category : Health & Fitness
ISBN : 0867154640

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Tissue Engineering by Samuel E. Lynch Pdf

This new edition reflects the remarkable clinical and scientific advances in bone and soft tissue reconstruction since publication of the first edition of this award-winning book 7 years ago. Highly potent recombinant growth factors are now widely available, and numerous chapters describe and provide cases illustrating how to incorporate these protein therapeutics into clinical practice. The reader will find information about the basic principles of tissue engineering, use of growth factors in orthopedics, and potential applications of gene therapy in dentistry. The book also features chapters on periodontal regeneration and localized implant site development. A section on applications for craniofacial reconstruction describes procedures for use of growth factors in the treatment of defects. The final section addresses orthopedic indications for tissue engineering. An invaluable, up-to-date resource for practitioners wanting to integrate tissue engineering into their clinical practice, researchers seeking inspiration for new directions, and those new to this fascinating field.

Author : Bernard George Sarnat
Publisher : Unknown
Page : 184 pages
File Size : 51,7 Mb
Release : 1951
Category : Anatomy, Comparative
ISBN : UCAL:B3846416

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The Temporomandibular Joint by Bernard George Sarnat Pdf

Author : Neil D. Broom,Ashvin Thambyah
Publisher : Cambridge University Press
Page : 403 pages
File Size : 48,8 Mb
Release : 2018-11-29
Category : Technology & Engineering
ISBN : 9781107137868

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The Soft–Hard Tissue Junction by Neil D. Broom,Ashvin Thambyah Pdf

Discover how the detailed structures of musculoskeletal tissue junctions relate to their mechanical function. This pioneering book, richly illustrated with tissue images, offers a rigorous, biomechanical approach to understanding the soft-hard tissue interface across multiple scales of resolution.

Author : Phuc Van Pham
Publisher : Springer
Page : 315 pages
File Size : 45,8 Mb
Release : 2017-01-24
Category : Science
ISBN : 9783319401447

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Bone and Cartilage Regeneration by Phuc Van Pham Pdf

This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.