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Author : W. Hamann,Ainsley Iggo
Publisher : Unknown
Page : 356 pages
File Size : 46,9 Mb
Release : 1988
Category : Récepteurs sensoriels - Congrès
ISBN : 0444801049
Author : Anonim
Publisher : Elsevier
Page : 353 pages
File Size : 51,6 Mb
Release : 2011-09-22
Category : Medical
ISBN : 9780080861999
Transduction and Cellular Mechanism in Sensory Receptors
Author : Laszlo Urban
Publisher : Springer Science & Business Media
Page : 501 pages
File Size : 48,5 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9783642787621
The research field of somatosensory processing in mammals has experienced revolutionary changes in recent years. Accumulation of basic and clinical data has greatly accelerated, and new phenomena have emerged. With the aid of new, refined methods, molecular and cellular changes have been described, underlying the signal transduction-transmission between the internal/external environment and the central nervous system have been described. The discovery of the interaction between the nervous and the immune system has, for example changed our view on the development of inflammatory diseases, while the cloning of genes encoding different trophic factors has boosted studies revealing profound changes in the regeneration of neurons, and induction of changes in phenotype. The study of the pre-and postsynaptic modulation of transmitter release, and the examination of the combined effects of amino acid and peptide transmitters has become recently possible by using cultured cell lines and in vitro techniques. Although it is in embryonic state, computational properties of single DRG cells under normal and pathological conditions are being investigated. Results soon or later will have a great impact on pain research and consequently ultimately in clinical pain management. This brief introduction indicates how our knowledge of the somatosensory system has increased dramatically recently. However, many investigators cultivate only a very specific field in the growing area of somatosensory research and find it difficult to integrate a more universal knowledge of their work.
Author : John L. Spudich,Birgit Satir
Publisher : Unknown
Page : 298 pages
File Size : 52,8 Mb
Release : 1991-10-23
Category : Medical
ISBN : UOM:39015024799689
Based on thought provoking overviews by experts in their fields, this topical book details engery-transducing and sensory systems which regulate cellular responses to chemical, light and other external stimuli. Probes mechanisms underlying regulatory pathways that have evolved with complex organisms from studies of chemotaxis and photoreception in bacterial model systems to genetic analysis of G-Protein coupled receptors in yeast.
Author : Wolfgang B. Liedtke, MD, PH.D.
Publisher : CRC Press
Page : 502 pages
File Size : 55,7 Mb
Release : 2006-09-29
Category : Medical
ISBN : 9781420005844
Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
Author : Dieter Wicher
Publisher : Frontiers E-books
Page : 147 pages
File Size : 42,8 Mb
Release : 2013-04-23
Category : Electronic
ISBN : 9782889191130
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Author : Krishna C. Persaud,Santiago Marco,Agustin Gutierrez-Galvez
Publisher : CRC Press
Page : 237 pages
File Size : 53,6 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781439871720
Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p
Author : Stephan Frings,Jonathan Bradley
Publisher : Wiley-VCH
Page : 0 pages
File Size : 51,7 Mb
Release : 2004-10-08
Category : Science
ISBN : 3527308369
The first book to link molecular biology with sensory physiology to explain the molecular mechanisms of sensory signal generation. The result is an authoritative overview of the mechanisms of sensory signal transduction in both animals and plants.
Author : Gordon L. Fain
Publisher : Unknown
Page : 294 pages
File Size : 46,6 Mb
Release : 2019-10
Category : Electronic
ISBN : 9780198835028
Provides a comprehensive and up-to-date review of transduction in various sensory modalities.
Author : Lindsay Biga,Devon Quick,Sierra Dawson,Amy Harwell,Robin Hopkins,Joel Kaufmann,Mike LeMaster,Philip Matern,Katie Morrison-Graham,Jon Runyeon
Publisher : Unknown
Page : 128 pages
File Size : 49,8 Mb
Release : 2019-09-26
Category : Electronic
ISBN : 1955101159
A version of the OpenStax text
Author : Friedrich Marks,Ursula Klingmüller,Karin Müller-Decker
Publisher : Garland Science
Page : 982 pages
File Size : 51,5 Mb
Release : 2017-05-17
Category : Medical
ISBN : 9781351677219
Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
Author : Frank Zufall,Steven D. Munger
Publisher : Academic Press
Page : 430 pages
File Size : 46,9 Mb
Release : 2016-02-18
Category : Science
ISBN : 9780128017869
Written by leaders in the field of chemosensation, Chemosensory Transduction provides a comprehensive resource for understanding the molecular mechanisms that allow animals to detect their chemical world. The text focuses on mammals, but also includes several chapters on chemosensory transduction mechanisms in lower vertebrates and insects. This book examines transduction mechanisms in the olfactory, taste, and somatosensory (chemesthetic) systems as well as in a variety of internal sensors that are responsible for homeostatic regulation of the body. Chapters cover such topics as social odors in mammals, vertebrate and invertebrate olfactory receptors, peptide signaling in taste and gut nutrient sensing. Includes a foreword by preeminent olfactory scientist Stuart Firestein, Chair of Columbia University’s Department of Biological Sciences in New York, NY. Chemosensory Transduction describes state-of-the-art approaches and key findings related to the study of the chemical senses. Thus, it serves as the go-to reference for this subject for practicing scientists and students with backgrounds in sensory biology and/or neurobiology. The volume will also be valuable for industry researchers engaged in the design or testing of flavors, fragrances, foods and/or pharmaceuticals. Provides a comprehensive overview for all chemosensory transduction mechanisms Valuable for academics focused on sensory biology, neurobiology, and chemosensory transduction, as well as industry researchers in new flavor, fragrance, and food testing Edited by leading experts in the field of olfactory transduction Focuses on mammals, but lower vertebrates and invertebrate model systems are also included
Author : Carla Mucignat-Caretta
Publisher : CRC Press
Page : 614 pages
File Size : 53,5 Mb
Release : 2014-02-14
Category : Medical
ISBN : 9781466553415
Intraspecific communication involves the activation of chemoreceptors and subsequent activation of different central areas that coordinate the responses of the entire organism—ranging from behavioral modification to modulation of hormones release. Animals emit intraspecific chemical signals, often referred to as pheromones, to advertise their presence to members of the same species and to regulate interactions aimed at establishing and regulating social and reproductive bonds. In the last two decades, scientists have developed a greater understanding of the neural processing of these chemical signals. Neurobiology of Chemical Communication explores the role of the chemical senses in mediating intraspecific communication. Providing an up-to-date outline of the most recent advances in the field, it presents data from laboratory and wild species, ranging from invertebrates to vertebrates, from insects to humans. The book examines the structure, anatomy, electrophysiology, and molecular biology of pheromones. It discusses how chemical signals work on different mammalian and non-mammalian species and includes chapters on insects, Drosophila, honey bees, amphibians, mice, tigers, and cattle. It also explores the controversial topic of human pheromones. An essential reference for students and researchers in the field of pheromones, this is also an ideal resource for those working on behavioral phenotyping of animal models and persons interested in the biology/ecology of wild and domestic species.
Author : Ruth Eatock,Richard R. Fay
Publisher : Springer Science & Business Media
Page : 465 pages
File Size : 47,8 Mb
Release : 2006-07-01
Category : Science
ISBN : 9780387317069
The Springer Handbook of Auditory Research presents a series of compreh- sive and synthetic reviews of the fundamental topics in modern auditory - search. The volumes are aimed at all individuals with interests in hearing research including advanced graduate students, postdoctoral researchers, and clinical investigators. The volumes are intended to introduce new investigators to important aspects of hearing science and to help established investigators to better understand the fundamental theories and data in ?elds of hearing that they may not normally follow closely. Each volume presents a particular topic comprehensively, and each serves as a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in peer-reviewed journals. The volumes focus on topics that have developed a solid data and conceptual foundation rather than on those for which a literature is only beginning to develop. New research areas will be covered on a timely basis in the series as they begin to mature.
Author : F. Javier Alvarez-Leefmans,Eric Delpire
Publisher : Academic Press
Page : 630 pages
File Size : 40,8 Mb
Release : 2009-08-22
Category : Medical
ISBN : 9780080922034
The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many years it was thought that Cl- was distributed in thermodynamic equilibrium across the plasma membrane of most cells. Research carried out during the last couple of decades has led to a dramatic change in this simplistic view. We now know that most animal cells, neurons included, exhibit a non-equilibrium distribution of Cl- across their plasma membranes. Over the last 10 to 15 years, with the growth of molecular biology and the advent of new optical methods, an enormous amount of exciting new information has become available on the molecular structure and function of Cl- channels and carriers. In nerve cells, Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control. Disruption of Cl- homeostasis in neurons underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation. This book is about how chloride ions are regulated and how they cross the plasma membrane of neurons. It spans from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases. The first comprehensive book on the structure, molecular biology, cell physiology, and role in diseases of chloride transporters / channels in the nervous system in almost 20 years Chloride is the most abundant free anion in animal cells. THis book summarizes and integrates for the first time the important research of the past two decades that has shown that Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control The first book that systematically discusses the result of disruption of Cl- homeostasis in neurons which underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation Spanning topics from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases Involves all of the leading researchers in the field Includes an extensive introductory section that covers basic thermodynamic and kinetics aspects of Cl- transport, as well as current methods for studying Cl- regulation, spanning from fluorescent dyes in single cells to knock-out models to make the book available for a growing population of graduate students and postdocs entering the field