Translational Research In Pain And Itch

Author : Chao Ma,Yuguang Huang
Publisher : Springer
Page : 147 pages
File Size : 40,5 Mb
Release : 2016-02-22
Category : Medical
ISBN : 9789401775373

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Translational Research in Pain and Itch by Chao Ma,Yuguang Huang Pdf

This book provides a comprehensive review of the latest advances in translational pain and itch research, and presents the cutting-edge developments in the study of our two principal, yet most mysteries sensations. Despite the slow progress in the discovery of effective therapies for chronic pain and pruritus, scientists around the globe now have a better understanding of why and how these conditions occur. Based on these findings, a series of novel treatment strategies are currently under development, and hopefully in a few years, medical practitioners will become more confident and optimistic when facing patients with these annoying and sometimes severe disorders. The contributing authors are world-renowned research scientists, who have made significant discoveries. The book is of interest to neuroscientists, neurologists and pharmacologists

Author : Gil Yosipovitch,Lars Arendt-Nielsen,Hjalte Andersen
Publisher : Lippincott Williams & Wilkins
Page : 473 pages
File Size : 51,6 Mb
Release : 2020-03-20
Category : Medical
ISBN : 9781975153052

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Itch and Pain by Gil Yosipovitch,Lars Arendt-Nielsen,Hjalte Andersen Pdf

Providing for the first time a comprehensive overview of the common and different pathways and mechanisms of itch and pain, this unique title explores these two distinct and still somehow similar sensory experiences and utilize the cross-fertilization between the two fields to develop better treatments for patients. Itch and Pain: Similarities, Interactions and Differences is the only available, up-to-date guide to current information in this important area, ideal for basic scientists as well as clinicians in dermatology, pain, neurology, medicine, psychology, or other specialties.

Author : Jiande Chen,Bruno Bonaz,Leo Cheng,Luming Li
Publisher : Frontiers Media SA
Page : 188 pages
File Size : 52,5 Mb
Release : 2022-02-25
Category : Science
ISBN : 9782889745357

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Translational Side of Emerging Invasive and Non-Invasive Stimulation Therapies by Jiande Chen,Bruno Bonaz,Leo Cheng,Luming Li Pdf

Author : Lawrence S Chan,Vivian Y. Shi
Publisher : Elsevier Health Sciences
Page : 317 pages
File Size : 48,6 Mb
Release : 2022-01-14
Category : Medical
ISBN : 9780323847452

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Atopic Dermatitis: Inside Out or Outside In by Lawrence S Chan,Vivian Y. Shi Pdf

Atopic dermatitis (eczema) is one of the most common and most challenging skin conditions, for patients and practitioners alike. Uniquely organized by intrinsic and extrinsic etiologies, Atopic Dermatitis: Inside Out or Outside In? examines a myriad of causes that start from both the inside of the body and from the external environment, offering physicians practical ways to design treatments that specifically address these causes. Drs. Lawrence S. Chan and Vivian Y. Shi, along with a team of expert contributing authors, examine the etiology of this complex disorder and provide targeted, comprehensive solutions and the most useful therapeutic plans based on pathophysiology, including evidence-based integrative management. Analyzes the pathophysiology of atopic dermatitis from two distinct fronts: inside out and outside in—an approach that is unique in the field. Begins with an overview of the disease, then delves into both internal and external pathogenic factors, followed by the Clinician’s Corner, which offers practical recommendations for treatment. Organizes therapeutic discussions by corresponding pathophysiology rather than a one-size-fits-all approach. Covers recently FDA-approved and emerging medications, as well as atopic comorbidities.

Author : Luana Colloca,Jason Noel,Chamindi Seneviratne,Patricia D. Franklin
Publisher : Oxford University Press
Page : 409 pages
File Size : 45,7 Mb
Release : 2023
Category : Medical
ISBN : 9780197645444

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Placebo Effects Through the Lens of Translational Research by Luana Colloca,Jason Noel,Chamindi Seneviratne,Patricia D. Franklin Pdf

"The challenge of improving health outcomes for individuals and populations remains daunting. Fortunately, collaboration among multiple disciplines accelerates our appreciation of innate and external determinants of health for individuals and populations. Interprofessional research, education and practice also strengthens our capacity to design, disseminate, and deliver effective strategies and policies to prevent and treat diseases, and improve health"--

Author : Sivapatham Sundaresan,Yeun-Hwa Gu
Publisher : BoD – Books on Demand
Page : 212 pages
File Size : 40,7 Mb
Release : 2021-02-03
Category : Medical
ISBN : 9781838805340

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Translational Research in Cancer by Sivapatham Sundaresan,Yeun-Hwa Gu Pdf

Translational research in oncology benefits from an abundance of knowledge resulting from genome-scale studies concerning the molecular pathways involved in tumorigenesis. Translational oncology represents a bridge between basic research and clinical practice in cancer medicine. The vast majority of cancer cases are due to environmental risk factors. Many of these environmental factors are controllable lifestyle choices. Experimental cancer treatments are studied in clinical trials to compare the proposed treatment to the best existing treatment through translational research. The key features of the book include: 1) New screening for the development of radioprotectors: radioprotection and anti-cancer effect of β-Glucan (Enterococcus faecalis) 2) Translational perspective on hepatocellular carcinoma 3) Brachytherapy for endometrial cancer 4) Discovery of small molecule inhibitors for histone methyltransferases in cancer

Author : Heather Batin
Publisher : Heather Batin
Page : 386 pages
File Size : 41,9 Mb
Release : 2024-02-29
Category : Medical
ISBN : 9780473696788

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Healing Chronic Pain by Heather Batin Pdf

This book is dedicated to everyone who lives with chronic pain. It details a family’s personal journey to understand and ultimately overcome this complex condition. The book includes personal reflections, neuroscientific research, theoretical frameworks and the practical plans and activities which the author’s daughter, Kerri, implemented to heal herself from pain and banish the debilitating symptoms which accompanied it from her life. Kerri and her mother hope this book will serve as an inspiration to others to re-examine their own relationship with pain, to find ways to understand and soothe it, and ultimately to heal from it, just as Kerri did.

Author : Daniel J. Pak,Jason Yong,Krishna Shah
Publisher : Elsevier Health Sciences
Page : 194 pages
File Size : 50,9 Mb
Release : 2020-10-17
Category : Medical
ISBN : 9780323757768

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Interventional Management of Chronic Visceral Pain Syndromes by Daniel J. Pak,Jason Yong,Krishna Shah Pdf

Offering timely coverage of this complex field, Interventional Management of Chronic Visceral Pain Syndromes is a practical, evidence-based guide for the mechanisms, presentation, diagnosis, and treatments of chronic non-malignant and malignant abdominal pain syndromes. Experienced clinicians and academic leaders in pain medicine comprehensively discuss best-practice guidelines using the newest interventional techniques, including dorsal root ganglion stimulation, high frequency spinal cord stimulation, and low-dose intrathecal infusion pumps. Coverage includes malignant and non-malignant gastrointestinal pain, malignant and non-malignant pelvic pain in males and females, rectal pain, and chest pain. Discusses key demographic characteristics as well as clinical and diagnostic presentations of the most common and esoteric visceral pain syndromes that will enable clinicians to identify pain generators. Provides a truly systematic approach to the treatment of chronic visceral pain, including the use of pharmacologic, non-interventional, interventional, and multidisciplinary therapies with evidence-based data. Covers the indications, contraindications, and outcomes results of the newest interventional treatments that all clinicians should be aware of, including neuromodulation and intrathecal pump therapy.

Author : Inna Belfer,Luda Diatchenko
Publisher : John Wiley & Sons
Page : 204 pages
File Size : 49,6 Mb
Release : 2013-11-15
Category : Science
ISBN : 9781118398852

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Pain Genetics by Inna Belfer,Luda Diatchenko Pdf

Pain Genetics: Basic to Translational Science is atimely synthesis of the key areas of research informing ourunderstanding of the genetic basis of pain. The book opens withfoundational information on basic genetic mechanisms underlyingpain perception and progresses recently discovered complex conceptsfacing the field. The coverage is wide-ranging and will serves asan excellent entry point into understating the genetics of pain aswell as providing a single resource for established researcherslooking for a better understanding of the diverse strands ofresearch going on in the area. With contributors painstakingly selected to provide a broad rangeof perspectives and research, Pain Genetics willbe a valuable resource for geneticists, neuroscientists, andbiomedical professionals alike.

Author : E. Carstens,Tasuku Akiyama
Publisher : CRC Press
Page : 482 pages
File Size : 51,9 Mb
Release : 2014-02-25
Category : Science
ISBN : 9781466505438

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Itch by E. Carstens,Tasuku Akiyama Pdf

Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.

Author : Ane C.F. Nunes
Publisher : BoD – Books on Demand
Page : 249 pages
File Size : 48,5 Mb
Release : 2020-01-08
Category : Medical
ISBN : 9781789843576

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Translational Studies on Inflammation by Ane C.F. Nunes Pdf

Inflammation is known worldwide, from the bench to the bedside, but it is a hard theme to approach with one single point of view.In this sense, a selection of translational studies would support the medical-scientific community to better understand the complex network of the inflammatory process, its maintenance, and potential treatment targets. The eleven chapters that compose this book present interesting insights into inflammation and its mechanisms, merging classic background with innovative approaches. From the molecular basis to experimental models, the chapters selected for this book bring to readers at different academic levels updated and practical data on inflammation. Find out what drives interdisciplinary medical research on inflammation and enjoy this informative collection.

Author : Sonja Ständer,Martin Schmelz,Yan-Gang Sun
Publisher : Frontiers Media SA
Page : 242 pages
File Size : 50,6 Mb
Release : 2021-11-24
Category : Medical
ISBN : 9782889716753

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Pruritus Medicine by Sonja Ständer,Martin Schmelz,Yan-Gang Sun Pdf

Author : Honorio Benzon,James P. Rathmell,Christopher L. Wu,Dennis Turk,Charles E. Argoff,Robert W Hurley
Publisher : Elsevier Health Sciences
Page : 1520 pages
File Size : 41,8 Mb
Release : 2022-02-10
Category : Medical
ISBN : 9780323711029

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Practical Management of Pain by Honorio Benzon,James P. Rathmell,Christopher L. Wu,Dennis Turk,Charles E. Argoff,Robert W Hurley Pdf

For more than 30 years, Practical Management of Pain has offered expert guidance to both clinicians and trainees, covering every aspect of acute and chronic pain medicine for adult and pediatric patients. The fully revised 6th Edition brings you fully up to date with new developments in patient evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. Edited by a team of renowned pain clinicians led by Dr. Honorio Benzon, this authoritative reference is a comprehensive, practical resource for pain diagnosis and treatment using a variety of pharmacologic and physical modalities. Presents a wealth of information in a clearly written, easily accessible manner, enabling you to effectively assess and draw up an optimal treatment plan for patients with acute or chronic pain. Takes a practical, multidisciplinary approach, making key concepts and techniques easier to apply to everyday practice. Shares the knowledge and expertise of global contributors on all facets of pain management, from general principles to specific management techniques. Discusses the latest, best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents such as topical analgesics. Covers recent global developments regarding opioid induced hyperalgesia, neuromodulation and pain management, and identification of specific targets for molecular based pain. Includes current information on the use of cannabinoids in pain management and related regulatory, professional, and legal considerations. Includes the latest guidelines on facet injections and safety of contrast agents. Provides new, evidence-based critical analysis on treatment modality outcomes and the latest information on chronic pain as a result of surgical interventions.

Author : Lei Zhou
Publisher : Springer Nature
Page : 407 pages
File Size : 40,6 Mb
Release : 2022-02-09
Category : Medical
ISBN : 9789811642548

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Ion Channels in Biophysics and Physiology by Lei Zhou Pdf

This book gathers relatively recent and significant topics in the field of ion channel research. Ion channels form the molecular basis for membrane excitability in cells present in the cardiovascular and nervous systems. In many non-excitable cells, ion channels contribute to diverse physiological functions, including the secretion of signaling compounds like hormones and insulin, cell volume regulation, intracellular signaling, especially Ca2+ signaling, etc. Many human diseases have been attributed to abnormal channel functions and defective membrane expression of channel proteins. On the other hand, ion channels are excellent models for studying protein biophysics, especially the allosteric regulation of protein function by miscellaneous stimuli. Therefore, research on ion channels carries significant meaning for the understanding of basic protein biophysics and diverse physiological functions. Such vital information also assists in developing novel and effective treatments for related human diseases. This book provides graduates and scientists in both basic and clinical levels a comprehensive understanding of cutting-edge advances and a useful and stimulating platform for tackling their own questions about ion channels.

Author : Rashid Giniatullin,Kalpna Gupta,Theoharis Constantin Theoharides
Publisher : Frontiers Media SA
Page : 194 pages
File Size : 49,5 Mb
Release : 2020-01-27
Category : Electronic
ISBN : 9782889633470

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Mast Cells in Itch, Pain and Neuro-inflammation by Rashid Giniatullin,Kalpna Gupta,Theoharis Constantin Theoharides Pdf