Understanding Brca

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Understanding BRCA

Clarissa Foster
Understanding BRCA Book PDF

Author : Clarissa Foster
Publisher : Unknown
Page : 0 pages
File Size : 52,5 Mb
Release : 2017
Category : BRCA genes
ISBN : 1781611203

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Understanding BRCA by Clarissa Foster Pdf

"Do you have a close relative who has died from, or is experiencing, aggressive breast, ovarian or prostate cancer? Have they been tested for the BRCA gene mutation? Have you? At the age of 35 and following the death of her mother from ovarian cancer, Clarissa Foster was found to carry a harmful mutation in the BRCA2 gene which drastically increased her risk of developing breast and ovarian cancer. She searched for a book that would help her to understand the full extent of what it meant to carry a harmful mutation, the options available to her to lower her risk and, most importantly, how it would feel to undergo risk-reducing surgery. Finding nothing that answered her needs, she set about reading all the available medical literature and liaising with relevant medical professionals to answer her questions. This book is the result of that research and of the decision she took based on it – to have a bilateral mastectomy and salpingo-oophorectomy. Within the context of her own painful experience of family cancer and of elective surgery, Clarissa explains what the BRCA mutation is, what it signifies, what the individual’s choices are and what the fall out can be in terms of a woman’s body image, identity and sexual functioning."--Publisher's description.

Confronting Hereditary Breast and Ovarian Cancer

Sue Friedman,Rebecca Sutphen,Kathy Steligo
Confronting Hereditary Breast and Ovarian Cancer Book PDF

Author : Sue Friedman,Rebecca Sutphen,Kathy Steligo
Publisher : JHU Press
Page : 320 pages
File Size : 45,9 Mb
Release : 2012-03-01
Category : Health & Fitness
ISBN : 9781421404455

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Confronting Hereditary Breast and Ovarian Cancer by Sue Friedman,Rebecca Sutphen,Kathy Steligo Pdf

"Be informed. Be empowered. Be well." If you are concerned that the cancer in your family is hereditary, you face difficult choices. Should you have a blood test that may reveal whether you have a high likelihood of disease? Do you preemptively treat a disease that may never develop? How do you make decisions now that will affect the rest of your life? This helpful, informative guide answers your questions as you confront hereditary breast and ovarian cancer. Developed by Facing Our Risk of Cancer Empowered (FORCE), the nation’s only nonprofit organization dedicated to supporting families affected by hereditary breast and ovarian cancer, this book stands alone among breast and ovarian cancer resources. Equal parts health guide and memoir, it defines complex issues facing previvors and survivors and provides solutions with a fresh, authoritative voice. Written by three passionate advocates for the hereditary cancer community who are themselves breast cancer survivors, Confronting Hereditary Breast and Ovarian Cancer dispels myths and misinformation and presents practical risk-reducing alternatives and decision-making tools. Including information about genetic counseling and testing, preventive surgery, and fertility and family planning, as well as explanations of health insurance coverage and laws protecting genetic privacy, this resource tackles head-on the challenges of living in a high-risk body. Confronting hereditary cancer is a complex, confusing, and highly individual journey. With its unique combination of the latest research, expert advice, and compelling personal stories, this book gives previvors, survivors, and their family members the guidance they need to face the unique challenges of hereditary cancer.

Resurrection Lily

Amy Byer Shainman
Resurrection Lily Book PDF

Author : Amy Byer Shainman
Publisher : Archway Publishing
Page : 231 pages
File Size : 46,8 Mb
Release : 2018-12-05
Category : Biography & Autobiography
ISBN : 9781480867079

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Resurrection Lily by Amy Byer Shainman Pdf

Resurrection Lily shares a story of inheritance and intuition, of what can surface in the body and the spirit when linked by DNA. As Amy Byer Shainman discovers she has inherited a BRCA gene mutation that puts her at high risk of developing certain cancers, she struggles to come to terms with preventively removing her breasts when she does not have a breast cancer diagnosis. Through her experience making decisions about her health, Amy becomes invigorated with purpose and establishes herself as a leading advocate for those with BRCA and other hereditary cancer syndromes, tirelessly working to educate others facing the same daunting reality. Painting a timely and moving portrait of what it feels like to carry a BRCA gene mutation, Resurrection Lily provides firsthand insight into the patient experience. Weaved throughout Amy’s open and vulnerable story is the expertise of her doctors, education from top medical experts in cancer genetics, and whispered lifesaving guidance from her grandmother Lillian.

Twisting Fate

Pamela Munster
Twisting Fate Book PDF

Author : Pamela Munster
Publisher : The Experiment
Page : 273 pages
File Size : 40,7 Mb
Release : 2018-09-25
Category : Biography & Autobiography
ISBN : 9781615194780

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Twisting Fate by Pamela Munster Pdf

From a woman who’s made her living researching breast cancer—and who lived through it herself—a personal yet practical guide to the medical and emotional facets of this life-changing diagnosis A leading oncologist at the University of California San Francisco, Dr. Pamela Munster has advised thousands of women on how to cope with the realities of breast cancer, from diagnosis through treatment and recovery. But her world turned upside down when, at forty-eight years old and in otherwise perfect health, she got a call saying that her own mammogram showed “irregularities.” That single word thrust her into a wholly new role—as patient, and not only that of cancer but of the feared BRCA gene mutation as well. Suddenly, she realized that being a true “expert” in a disease was far beyond the scope of her medical training, and that she had a lot to learn if she wanted to hold onto her precious life. Weaving together her personal story with groundbreaking research on BRCA—responsible for breast cancer and many other inherited cancers affecting both women and men—Twisting Fate is an inspiring guide to living with the uncertainties of cancer. With authority, insight, and compassion, Dr. Munster uses her voice to create a safe space for genuine healing and honesty in a world otherwise too-often dominated by fear—and she is living proof of how important it is to embrace all the twists and turns of fate.

Previvors

Dina Roth Port
Previvors Book PDF

Author : Dina Roth Port
Publisher : Penguin
Page : 240 pages
File Size : 55,8 Mb
Release : 2010-10-05
Category : Health & Fitness
ISBN : 9781101443910

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Previvors by Dina Roth Port Pdf

The first guide to all surgical and nonsurgical options for women with a high risk for breast cancer. Advances in genetic testing and risk assessment have changed the face of medicine, but with them has come a Pandora's box of dilemmas. Imagine discovering you had a significant risk for developing breast cancer. What would you do? Through the incredible true stories of five young friends, as well as interviews with more than seventy top breast cancer experts, health writer Dina Roth Port addresses the universal questions of women everywhere who have watched family members suffer from the disease and wondered, "Am I next?" Full of practical information, Previvors is the first comprehensive book to guide women through the difficult process of determining their risk, weighing the options, and coping with the emotions of deciding to undergo surgery. Readers will learn: •The pros and cons of getting tested for the BRCA gene •How to decide between surgical or nonsurgical options •The latest research in breast cancer surveillance •The advanced new world of breast reconstruction •How to overcome body image and sex issues post-surgery, and more From navigating health insurance coverage to finding the right medical team, Previvors is an invaluable resource for women facing decisions about their risk and future health. Watch a Video

Cancer and the Environment

Institute of Medicine,Board on Health Sciences Policy,Roundtable on Environment Health Sciences, Research, and Medicine
Cancer and the Environment Book PDF

Author : Institute of Medicine,Board on Health Sciences Policy,Roundtable on Environment Health Sciences, Research, and Medicine
Publisher : National Academies Press
Page : 160 pages
File Size : 47,5 Mb
Release : 2002-08-01
Category : Science
ISBN : 9780309169240

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Cancer and the Environment by Institute of Medicine,Board on Health Sciences Policy,Roundtable on Environment Health Sciences, Research, and Medicine Pdf

The Roundtable on Environmental Health Sciences, Research, and Medicine wanted to address the link between environmental factors and the development of cancer in light of recent advances in genomics. They asked what research tools are needed, how new scientific information can be applied in a timely manner to reduce the burden of cancer, and how this can be flexible enough to treat the individual.

Being at Genetic Risk

Kelly Pender
Being at Genetic Risk Book PDF

Author : Kelly Pender
Publisher : Penn State Press
Page : 185 pages
File Size : 44,9 Mb
Release : 2020-04-27
Category : Language Arts & Disciplines
ISBN : 9780271083025

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Being at Genetic Risk by Kelly Pender Pdf

Rhetorics of choice have dominated the biosocial discourses surrounding BRCA risk for decades, telling women at genetic risk for breast and ovarian cancers that they are free to choose how (and whether) to deal with their risk. Critics argue that women at genetic risk are, in fact, not free to choose but rather are forced to make particular choices. In Being at Genetic Risk, Kelly Pender argues for a change in the conversation around genetic risk that focuses less on choice and more on care. Being at Genetic Risk offers a new set of conceptual starting points for understanding what is at stake with a BRCA diagnosis and what the focus on choice obstructs from view. Through a praxiographic reading of the medical practices associated with BRCA risk, Pender’s analysis shows that genetic risk is not just something BRCA+ women know, but also something that they do. It is through this doing that genetic cancer risk becomes a reality in their lives, one that we can explain but not one that we can explain away. Well researched and thoughtfully argued, Being at Genetic Risk will be welcomed by scholars of rhetoric and communication, particularly those who work in the rhetoric of science, technology, and medicine, as well as scholars in allied fields who study the social, ethical, and political implications of genetic medicine. Pender’s insight will also be of interest to organizations that advocate for those at genetic risk of breast and ovarian cancers.

Positive Results

Joi L. Morris,Ora K. Gordon, M.D.
Positive Results Book PDF

Author : Joi L. Morris,Ora K. Gordon, M.D.
Publisher : Prometheus Books
Page : 397 pages
File Size : 43,6 Mb
Release : 2010-06-03
Category : Health & Fitness
ISBN : 9781615927739

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Positive Results by Joi L. Morris,Ora K. Gordon, M.D. Pdf

This unique and important guidebook is a single, comprehensive source of information and advice to help women (and some men) at high risk for breast and for ovarian cancer because of family history and genetic profile. One part memoir, three parts "how to" manual, Positive Results explains in a clear and steady manner the myths and realities of "the breast cancer genes." It lays out all the options in easy-to-follow, compassionate language. It will help women and men decide if they want to pursue genetic testing, guide them in interpreting their test results, and give them a sound basis for making the life-saving decisions required to manage their risks. Authors Joi Morris and Dr. Ora Karp Gordon cover all of the latest medical options, including genetic testing for breast cancer risk, breast cancer surveillance, assessing risk, mastectomy and breast reconstruction techniques, ovarian cancer surveillance, surgery, managing menopause, and cancer risks in men who carry mutations on BRCA genes. Along the way, Joi tells her personal story and that of other women and men who have made the gut-wrenching decisions required to survive in this world of astronomical risk. At the age of forty-two, Joi learned that she has a genetic mutation on a gene known as BRCA2. The test results meant that her risk of getting breast cancer could be as high as 84 percent by age seventy, and that her risk for ovarian cancer was also high. Compounding her risk was the fact that her mother had developed breast cancer in her forties. After much research and consultation, the result of which is this book, Joi made the difficult decision of undergoing prophylactic mastectomies. This straightforward and practical approach combined with the poignant personal experience of a woman at risk facing these challenging decisions will provide readers with the feeling that they have had the benefit of a long conversation with both a trusted physician and a friend who has just gone through the same uncertainties they are facing.

Mammography and Beyond

National Research Council,Commission on Life Sciences,Institute of Medicine,National Cancer Policy Board,Committee on the Early Detection of Breast Cancer
Mammography and Beyond Book PDF

Author : National Research Council,Commission on Life Sciences,Institute of Medicine,National Cancer Policy Board,Committee on the Early Detection of Breast Cancer
Publisher : National Academies Press
Page : 34 pages
File Size : 51,5 Mb
Release : 2001-06-04
Category : Medical
ISBN : 9780309075503

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Mammography and Beyond by National Research Council,Commission on Life Sciences,Institute of Medicine,National Cancer Policy Board,Committee on the Early Detection of Breast Cancer Pdf

X-ray mammography screening is the current mainstay for early breast cancer detection. It has been proven to detect breast cancer at an earlier stage and to reduce the number of women dying from the disease. However, it has a number of limitations. These current limitations in early breast cancer detection technology are driving a surge of new technological developments, from modifications of x-ray mammography such as computer programs that can indicate suspicious areas, to newer methods of detection such as magnetic resonance imaging (MRI) or biochemical tests on breast fluids. To explore the merits and drawbacks of these new breast cancer detection techniques, the Institute of Medicine of the National Academy of Sciences convened a committee of experts. During its year of operation, the committee examined the peer-reviewed literature, consulted with other experts in the field, and held two public workshops. In addition to identifying promising new technologies for early detection, the committee explored potential barriers that might prevent the development of new detection methods and their common usage. Such barriers could include lack of funding from agencies that support research and lack of investment in the commercial sector; complicated, inconsistent, or unpredictable federal regulations; inadequate insurance reimbursement; and limited access to or unacceptability of breast cancer detection technology for women and their doctors. Based on the findings of their study, the committee prepared a report entitled Mammography and Beyond: Developing Technology for Early Detection of Breast Cancer, which was published in the spring of 2001. This is a non-technical summary of that report.

Understanding Breast Cancer Genetics

Barbara T. Zimmerman
Understanding Breast Cancer Genetics Book PDF

Author : Barbara T. Zimmerman
Publisher : Univ. Press of Mississippi
Page : 142 pages
File Size : 46,7 Mb
Release : 2004
Category : Health & Fitness
ISBN : 157806578X

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Understanding Breast Cancer Genetics by Barbara T. Zimmerman Pdf

Health & Sickness -- Consumer Health This book by a scientist whose background is in cellular and molecular biology examines the fearsome disease that strikes one in eight women in the United States. Although women are more likely to die of heart disease or of lung cancer, a diagnosis of breast cancer is the medical pronouncement that a woman is most likely to fear. It kills more than 40,000 Americans annually. Why are some women more vulnerable than others? The interplay between genetics and environment is suspected. Thus this book for general readers will help them understand the genetic bases of both sporadic and inherited breast cancers. Although only five to ten percent of breast cancer patients have inherited mutations in these genes, all women need to understand the genetic implications of the disease. In clear, concise language Barbara T. Zimmerman guides the reader through the complexities, discussing in detail the genes that are known to increase susceptibility and the ways they are passed on. Examining the general biology of breast cancer, Zimmerman describes how sporadic and inherited forms of the disease arise and how the location of the tumors can affect the body. She discusses genetic mutations and their roles in the development of tumors and tells how these potentially cancer-inducing genes were discovered. Covered too are the issues of risk, prevention, screening, diagnosis, therapy, and genetic testing and counseling. Zimmerman concludes with a comprehensive analysis of current research and with an emphasis on how a woman's understanding of inherited breast cancer can help doctors seeking to design better methods for prevention and therapy. A useful list of resources for further information about the genetic causes of breast cancer is included. Barbara T. Zimmerman did her graduate work in experimental pathology and her post-doctoral research in the cellular and molecular processes of disease. Widely published, she is the manager of the Denver-based firm Biomedical Communication and Consulting.

Probably Someday Cancer

Kim Horner
Probably Someday Cancer Book PDF

Author : Kim Horner
Publisher : University of North Texas Press
Page : 209 pages
File Size : 46,6 Mb
Release : 2019-02-15
Category : Biography & Autobiography
ISBN : 9781574417579

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Probably Someday Cancer by Kim Horner Pdf

After learning that she inherited a BRCA2 genetic mutation that put her at high risk for breast and ovarian cancer, Kim Horner’s doctors urged her to consider having a double mastectomy. But how do you decide whether to have a surgery to remove your breasts to reduce your risk for a disease you don’t have and may never get? Horner shares her struggle to answer that question in Probably Someday Cancer. The mother of a one-year-old boy, she wanted to do whatever would give her the best odds of being around for her son and protect her from breast cancer, which killed her grandmother and great-grandmother in their 40s. Which would give her the best chance at a long healthy life: a double mastectomy or frequent screenings to try to catch any cancer early? The answers weren’t that simple. Based on extensive research, interviews, and personal experience, Horner writes about how and why she ultimately opted for a double mastectomy—the same decision actress Angelina Jolie made for a similar genetic mutation—and the surprising diagnosis that followed. The book explores difficult truths that get overshadowed by upbeat messages about early detection and survivorship—the fact that screenings can miss cancers and that even early-stage breast cancers can spread and become fatal. Probably Someday Cancer is about the author’s efforts to push past her fear and anxiety. This book can help anyone facing hereditary risk of breast and ovarian cancer feel less alone and make informed decisions to protect their health and end the devastation that hereditary cancer has caused for generations in so many families.

Living with Hereditary Cancer Risk

Kathy Steligo,Sue Friedman,Allison W. Kurian
Living with Hereditary Cancer Risk Book PDF

Author : Kathy Steligo,Sue Friedman,Allison W. Kurian
Publisher : JHU Press
Page : 496 pages
File Size : 40,7 Mb
Release : 2022-09-27
Category : Health & Fitness
ISBN : 9781421444253

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Living with Hereditary Cancer Risk by Kathy Steligo,Sue Friedman,Allison W. Kurian Pdf

"This book provides a comprehensive overview of hereditary cancer for a general audience, with coverage of the genetic tests available for detecting risk for heritable cancers as well as options for medical and surgical treatment"--

Pretty Is What Changes

Jessica Queller
Pretty Is What Changes Book PDF

Author : Jessica Queller
Publisher : Random House
Page : 258 pages
File Size : 55,6 Mb
Release : 2008-04-01
Category : Biography & Autobiography
ISBN : 9780385525718

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Pretty Is What Changes by Jessica Queller Pdf

Faced with the BRCA mutation—the so-called “breast cancer gene”—one woman must answer the question: When genetics can predict how we may die, how then do we decide to live? Eleven months after her mother succumbs to cancer, Jessica Queller has herself tested for the BRCA gene mutation. The results come back positive, putting her at a terrifyingly elevated risk of developing breast cancer before the age of fifty and ovarian cancer in her lifetime. Thirty-four, unattached, and yearning for marriage and a family of her own, Queller faces an agonizing choice: a lifetime of vigilant screenings and a commitment to fight the disease when caught, or its radical alternative—a prophylactic double mastectomy that would effectively restore life to her, even as it would challenge her most closely held beliefs about body image, identity, and sexuality. Superbly informed and armed with surprising wit and style, Queller takes us on an odyssey from the frontiers of science to the private interiors of a woman’s life. Pretty Is What Changes is an absorbing account of how she reaches her courageous decision and its physical, emotional, and philosophical consequences. It is also an incredibly moving story of what we inherit from our parents and how we fashion it into the stuff of our own lives, of mothers and daughters and sisters, and of the sisterhood that forms when women are united in battle against a common enemy. Without flinching, Jessica Queller answers a question we may one day face for ourselves: If genes can map our fates and their dark knowledge is offered to us, will we willingly trade innocence for the information that could save our lives? Praise for Pretty Is What Changes “By turns inspiring, sorrowful and profoundly moving. Queller’s sense of humor and grace transform the most harrowing of situations into a riveting and heartfelt memoir.”—Kirkus Reviews “Seamless and gripping. Readers will be rooting for Queller and her heroic decision to confront her genetic destiny.”—Publishers Weekly “Jessica Queller gives us a warm, chilling, unflinching look at her personal journey of survival with style. The ending will surprise you. Her prescience is astounding. Her courage is inspirational. Brava Jessica!”—Marisa Acocella Marchetto, author of Cancer Vixen

Approaches to Understanding Breast Cancer

Anonim
Approaches to Understanding Breast Cancer Book PDF

Author : Anonim
Publisher : Academic Press
Page : 294 pages
File Size : 55,8 Mb
Release : 2017-10-27
Category : Science
ISBN : 9780128127735

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Approaches to Understanding Breast Cancer by Anonim Pdf

Approaches to Understanding Breast Cancer, Volume 151, the latest volume in the Progress in Molecular Biology and Translational Science series focuses on breast cancer, with new chapters that include information on Breast Cancer Epidemiology, Prevention, and Screening, DCIS: Current Principles of Management, Pregnancy and Hormonal Prevention of Breast Cancer, Chemokines: Key Players in Pathobiology of Breast Cancer, Mircrobiota and Breast Cancer, Experimental Therapeutic Use of Estrogen Receptor Beta Agonists in Prevention and Treatment of Endocrine Therapy Resistant Breast Cancers: Observations from Pre-Clinical Models, Targeting Breast Cancer Stem Cells: Key for Anti-Metastatic Therapy, and Experimental Therapy of Advanced Breast Cancer: Target NFAT1-MDM2-p53 Pathway. Accessible to students and researchers alike Written by leading authorities in the field

Managing BRCA Mutation Carriers

Anees B. Chagpar
Managing BRCA Mutation Carriers Book PDF

Author : Anees B. Chagpar
Publisher : Springer
Page : 242 pages
File Size : 47,8 Mb
Release : 2017-07-13
Category : Medical
ISBN : 9783319591988

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Managing BRCA Mutation Carriers by Anees B. Chagpar Pdf

As there are a number of nuances in terms of how to manage mutation carriers (both with and without a concomitant diagnosis of breast cancer), this text provides a comprehensive, state-of-the art review of this field. It represents a valuable resource for a myriad of clinicians and healthcare personnel who interface with these patients. The text discusses the latest recommendations for genetic counseling and risk assessment, provides a framework for considering reducing risk in mutation carriers who do not present with a concomitant diagnosis of breast cancer, and finally elucidates the many considerations of managing a breast cancer patient with a BRCA mutation. The text presents a multidisciplinary approach gleaning insights from imaging, breast surgery, gynecology, plastic surgery, medical oncology, radiation oncology and psycho-oncology. Managing BRCA Mutation Carriers will be a useful resource for physicians and healthcare providers from a myriad of disciplines who manage BRCA mutation carriers. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.