Unraveling The Safety Profile Of Nanoscale Particles And Materials
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Unraveling the Safety Profile of Nanoscale Particles and Materials by Andreia Ferreira de Castro Gomes,Marisa P. Sárria Pdf
As nanomaterials become increasingly present in our daily lives, pertinent questions regarding their safety arise. Nanomaterial risk assessment, as in other areas, directs much of the effort worldwide in defining guidelines that may be translated into national or international directives. Nanomaterials encompass different entities, from nanoparticles to nanostructured materials, with specific effects over cells, tissues, organisms and ecosystems depending on their biophysical characteristics. Such interactions will directly affect the impact of novel nanotechnologies. This book aims to provide the reader with a comprehensive overview of the current state of the art in nanotoxicology, featuring the most important developments and critical issues regarding the use of and exposure to nanoparticles.
Safety of Nanomaterials along Their Lifecycle by Wendel Wohlleben,Thomas A.J. Kuhlbusch,Jürgen Schnekenburger,Claus-Michael Lehr Pdf
The incorporation of nanomaterials into products can improve performance, efficiency, and durability in various fields ranging from construction, energy management, catalysis, microelectronics, plastics, coatings, and paints to consumer articles such as foods and cosmetics. But innovation never comes at zero risk. The potential hazards resulting from human exposure during production, use, or disposal has raised concerns and targeted research early on. Safety of Nanomaterials along Their Lifecycle: Release, Exposure, and Human Hazards presents the state of the art in nanosafety research from a lifecycle perspective. Although major knowledge gaps still exist, solid data are now available to identify scenarios of critical risk as well as those of safe nanomaterial use for our benefit. The book is divided into four parts: characterization, hazard, release and exposure, and real-life case studies. To improve coherence throughout the book, various chapters review the same suite of well-characterized, judiciously chosen, and identical industrial nanomaterials. The book is a helpful resource to professionals in product development, industrial design, regulatory agencies, and materials scientists and engineers involved in the safety of nanomaterials.
Health and Environmental Safety of Nanomaterials by James Njuguna,Krzysztof Pielichowski,Huijun Zhu Pdf
The first edition of Health and Environmental Safety of Nanomaterials: Polymer Nanocomposites and Other Materials Containing Nanoparticles was published in 2014, but since that time, new developments in the field of nanomaterials safety have emerged, both at release and exposure, along with the expanding applications of the nanomaterials side. Numerous studies have been dedicated to the issue of biophysical interactions of nanoparticles with the human body at the organ, cellular, and molecular levels. In this second edition, all the chapters have been brought fully up to date. There are also four brand new chapters on the biophysical interaction of nanoparticles with the human body; advanced modeling approaches to help elucidate the nanorisks; safety measures at work with nanoparticles; and the health and environmental risks of graphene. It provides key knowledge and information needs for all those who are working in the research and development sector and need to learn more about the safety of nanomaterials. • Focuses on the health and safety of polymer nanocomposites and other materials containing nanoparticles, as well as their medical and environmental implications • Discusses the fundamental nature of various biophysical interactions of nanoparticles with the human body • Looks at the physico-chemistry of nanoparticles and their uptake, translocation, transformation, transport, and biodistribution in mammalian and plant systems • Presents the structure–activity relationships and modeling of the interactions of nanoparticles with biological molecules, biochemical pathways, analysis of biomolecular signatures, and the development of biomarkers.
Nanotechnology for Hematology, Blood Transfusion, and Artificial Blood by Adil Denizli,Tuan Anh Nguyen,Rajan Mariappan,Mohammad Feroz Alam,Khaliqur Rahman Pdf
Nanotechnology for Hematology, Blood Transfusion, and Artificial Blood outlines the fundamental design concepts and emerging applications of nanotechnology in hematology, blood transfusion and artificial blood. This book is an important reference source for materials scientists, engineers and biomedical scientists who are looking to increase their understanding of how nanotechnology can lead to more efficient blood treatments. Sections focus on how nanotechnology could offer new routes to address challenging and pressing issues facing rare blood diseases and disorders and how nanomaterials can be used as artificial cell-like systems (compartmentalized biomimetic nanocontainers), which are especially useful in drug delivery. For artificial blood, the nanotechnological approach can fabricate artificial red blood cells, platelet substitutes, and white blood cell substitutes with their inherent enzyme and other supportive systems. In addition, nanomaterials can promote blood vessel growth and reserve red blood cells at a positive temperature. Provides information on how nanotechnology can be used to create more efficient solutions for blood transfusions and hematology treatments Explores the major nanomaterial types that are used for these treatments Assesses the major challenges of using nanomaterials hematology
Ethics in Nanotechnology by Marcel Van de Voorde,Gunjan Jeswani Pdf
With nanotechnology being a relatively new field, the questions regarding safety and ethics are steadily increasing with the development of the research. This book aims to give an overview on the ethics associated with employing nanoscience for products with everyday applications. The risks as well as the regulations are discussed, and an outlook for the future of nanoscience on a manufacturer’s scale and for the society is provided. Ethics in nanotechnology is a valuable resource for, philosophers, academicians and scientist, as well as all other industry professionals and researchers who interact with emerging social and philosophical ethical issues on routine bases. It is especially for deep learners who are enthusiastic to apprehend the challenges related to nanotechnology and ethics in philosophical and social education. This book presents an overview of new and emerging nanotechnologies and their societal and ethical implications. It is meant for students, academics, scientists, engineers, policy makers, ethicist, philosophers and all stakeholders involved in the development and use of nanotechnology.
Measuring Biological Impacts of Nanomaterials by Joachim Wegener Pdf
This book reviews several aspects of the biological response to nanoscale particles on a molecular and cellular level. Nanoscale materials and nanoscale particles in particular have interesting properties and beneficial applications. While they thus have entered our daily lifes on many different levels (from electronics, over textiles, packaging or surface modifications, to biomedical applications), general rules describing their interaction with biological structures and biological matter are still difficult to derive. The existing literature suggests a variety of interaction schemes between nanoparticles and biological objects, not dispelling the public concerns about possible health effects and harmful properties. A systematic approach to the problem is needed and timely. This book specifically emphasizes bioanalytical problems starting from the characterization of the nanomaterials to the pitfalls and potential artifacts of state-of-the-art cytotoxicity assays that are frequently used to study harmful effects on cells. It also highlights the application of label-free bioanalytical techniques that can potentially complement the present approaches and hence provide new perspectives on this highly discussed cutting-edge field of research and public concern.
This award-winning textbook delivers an earnest and comprehensive treatment of the rapidly evolving field of Materials Chemistry. It addresses inorganic-, organic-, and nano-based materials from a structure vs. property treatment, providing a suitable breadth and depth coverage of the field—in a concise and accessible format. The updated 4th edition features significant updates to glasses and ceramics, solid-state impurities, nanomaterial toxicity, as well as materials used in energy storage, photovoltaic, and electronics applications. Advanced fabrication techniques such as additive manufacturing (3-D printing) and dynamic light scattering (DLS) characterization of suspended nanoparticles are now also included. This new edition also expands the coverage of sustainability and life cycle analysis, of increasing importance for a world plagued with the effects of climate change. Recognized by a 2008 Textbook Excellence Award from the Text and Academic Authors Association (TAA), Fahlman’s Materials Chemistry is ideal for upper-level undergraduate students, as well as first-year graduate students in chemistry, physics, or engineering fields, and may also serve as a valuable reference to industrial researchers. Each chapter concludes with a section that describes important materials applications and an updated list of thought-provoking questions.
Environmental Nanotoxicology by Patrick Omoregie Isibor,Geetha Devi,Alex Ajeh Enuneku Pdf
Environmental Nanotoxicology: Combatting the Minute Contaminants is a comprehensive guide to the rapidly evolving field of nanotoxicology and its implications for environmental health and safety. This book results from the collaborative efforts of leading experts and researchers from diverse disciplines, aiming to thoroughly understand the interactions between nanomaterials and the environment and their potential impacts on the delicate balance of our ecosystems. Nanotechnology has witnessed remarkable innovations leading to the development of nanomaterials with novel properties and applications across various industries. Alongside these innovations, concerns have arisen about the potential risks that nanomaterials may pose to the environment and living organisms. This book addresses these concerns by comprehensively exploring the field's key concepts, principles, and methodologies. It includes case studies and offers insights into developing appropriate regulatory frameworks and guidelines for the responsible use and disposal of nanomaterials. The book is a valuable resource for researchers and professionals working in nanotoxicology on the complex challenges posed by the intersection of nanomaterials and the environment. It is also an essential reference for students studying environmental science, toxicology, and nanotechnology. Addresses risk assessment and management in nanotoxicology; Explores the life cycle assessment of nanoparticles; Sheds light on emerging technologies and future directions in environmental nanotoxicology. .
Handbook of Nanomaterials for Sensing Applications by Chaudhery Mustansar Hussain,Suresh Kumar Kailasa Pdf
Handbook of Nanomaterials for Intelligent Sensing Applications provides insights into the production of nanosensors and their applications. The book takes an interdisciplinary approach, showing how nano-enhanced sensing technology is being used in a variety of industry sectors and addressing related challenges surrounding the production, fabrication and application of nanomaterials-based sensors at both experimental and theoretical levels. This book is an important reference source for materials scientists and engineers who want to learn more about how nanomaterials are being used to enhance sensing products and devices for a variety of industry sectors. The pof miniaturized device components and engineering systems of micro- and nanoscale is beyond the capability of conventional machine tools. The production of intelligent sensors at nanometer scale presents great challenges to engineers in design and manufacture. The manufacturing of nano-scaled devices and components involves isolation, transportation and re-assembly of atoms and molecules. This nanomachining technology involves not only physical-chemical processes as in the case of microfabrication, but it also involves application and integration of the principles of molecular biology. Explains how the functionalization of nanomaterials is being used to create more effective sensors Explores the major challenges of using nanoscale sensors for industrial applications on a broad scale Assesses which classes of nanomaterial should best be used for sensing applications
Nanotechnological Approaches in Food Microbiology by Sanju Bala Dhull,Prince Chawla,Ravinder Kaushik Pdf
Nanotechnology has gained attention in all aspects of modern science, having vital applications in the food chain, storage, quality monitoring, processing, preservation, and packaging. The global population is increasing rapidly, therefore there is a requirement to produce food products in a more proficient, non-toxic, and sustainable way. Food scientists and microbiologists are interested in food safety and quality assurance to produce excellent-quality food free of food pathogens Nanotechnological Approaches in Food Microbiology provides a systematic introduction and comprehensive information about practical approaches and characteristic features related to the significant applications of nanotechnology in food microbiology, including, nano-starch films, nanoemulsions, biogenic nanoparticles, and nanocapsules. The book will explore details about metal nanoparticle synthesis, characterization, mathematical modeling, kinetic studies, and their antimicrobial approaches. Key Features: Includes comprehensive knowledge on metal nanoparticle synthesis, characterization, mathematical modeling, kinetic studies and their antimicrobial approaches Lays out concepts of essential oil nanoemulsion and their potential antimicrobial applications Deals with the latest development in nano-starch composite biofilms containing bioactive constituents to inhibit pathogenic microbes Explores the nanocapsules as potential antimicrobial agents in food. Provides information regarding new biogenic nano-antimicrobials developed for the food safety and quality assurance This book will educate readers on the aspects of nanotechnology in food safety and quality assurance. Nanoemulsions, nanohydrogels, metal nanoparticles, nano-starch films, nanocapsules and nano-antimicrobials are the emerging essentials of nanotechnology that are used to preserve the food at greater extent. This book should be of interest to a large and varied audience of researchers in academia, industry, food processing, preservation, packaging, microbiology and policy regulations.
Sample Preparation with Nanomaterials by Chaudhery Mustansar Hussain,Rustem Kecili,Chaudhery Ghazanfar Hussain Pdf
Discover this timely, comprehensive, and up-to-date exploration of crucial aspects of the use of nanomaterials in analytical chemistry Sample Preparation with Nanomaterials: Next Generation Techniques for Sample Preparation delivers insightful and complete overview of recent progress in the use of nanomaterials in sample preparation. The book begins with an overview of special features of nanomaterials and their applications in analytical sciences. Important types of nanomaterials, like carbon nanotubes and magnetic particles, are reviewed and biological sample preparation and lab-on-a-chip systems are presented. The distinguished author places special emphasis on approaches that tend to green and reduce the cost of sample treatment processes. He also discusses the legal, economical, and toxicity aspects of nanomaterial samples. This book includes extensive reference material, like a complete list of manufacturers, that makes it invaluable for professionals in analytical chemistry. Sample Preparation with Nanomaterials offers considerations of the economic aspects of nanomaterials, as well as the assessment of their toxicity and risk. Readers will also benefit from the inclusion of: A thorough introduction to nanomaterials in the analytical sciences and special properties of nanomaterials for sample preparation An exploration of the mechanism of adsorption and desorption on nanomaterials, including carbon nanomaterials used as adsorbents Discussions of membrane applications of nanomaterials, surface enhanced raman spectroscopy, and the use of nanomaterials for biological sample preparation A treatment of magnetic nanomaterials, lab-on-a-chip nanomaterials, and toxicity and risk assessment of nanomaterials Perfect for analytical chemists, materials scientists, and process engineers, Sample Preparation with Nanomaterials: Next Generation Techniques for Sample Preparation will also earn a place in the libraries of analytical laboratories, universities, and companies who conduct research into nanomaterials and seek a one-stop resource for sample preparation.
The Era of Assisted Reproductive Technologies Tailored to the Specific Necessities of Species, Industry and Case Reports by David Martín Hidalgo Pdf
Nowadays, assisted reproductive technologies (ARTs) have a pivotal role not only in achieving fertilization in subfertile animals, but they are also involved in the management of the herd, decreasing disease spread and even allowing offspring sex selection. Nonetheless, there are differences between species or even within species that have led researchers worldwide to focus on those differences in order to bypass these specific difficulties. This Special Issue, titled “The Era of Assisted Reproductive Technologies Tailored to the Specific Necessities of Species, Industry and Case Reports” and published in Animals, is composed of 12 original manuscripts and three reviews that offer an overview of current and future ARTs used to improve reproductive outcomes, mainly focused on farm animals, such as horse, pig, bovine, rabbit and ovine species. Thus, the Special Issue covers information from the classical point of view, including comparative studies of different semen extenders, to the most advanced technologies of sperm selection by thermotaxis or chemoattractants, as well as the improvement of sperm features by red light irradiation. The female and embryo contributions to ART outcomes are also covered, for instance, with a study that improves our knowledge by the metabolomic description of follicular fluid composition or the description of better culture conditions of oocytes. In brief, this Special Issue provides a balanced overview of emerging techniques and technologies used to preserve, improve, rescue or even create fertility for domestic farm animals with high economic impact.
New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications by Marc J.M. Abadie,Mariana Pinteala,Alexandru Rotaru Pdf
This contributed volume applies the insights of supramolecular chemistry to biomedical applications such as ions/water transport through nano-scale channels, gene therapy, tissue engineering and drug delivery, to cite some of the major investigations.The challenge is to understand the mechanisms of transport through tissues particularly in the therapeutic treatment of a disease where the active drug must be delivered directly to diseased cells without affecting healthy cells. As a result, smaller quantities of active substances can be used to treat the disease. Another interest concerns new ways to administer gene therapy. If genes are often delivered to their target cells by adapted viruses, the supramolecular non-viral ‘vectors’ using dynamic nano-frameworks and nano-structures are presented. In addition, it is important to reconstruct damaged tissues by mimicking natural processes in cells and polymers, such as tissue engineering and self-healing. Different options are here discussed: e.g. hydrogels based on chitosan, a carbohydrate polymer, are proving especially promising for tissue engineering and drug delivery. For controlled delivery of drugs or other biologically active compounds, hydrogels sensitive to the most important stimuli in the human body, such as temperature, pH, ionic strength, glucose and biomolecules released by the organism in pathological conditions have been developed. Finally, to assist and validate the experimental studies, computer modelling and simulations of large-sized molecular structures and systems using different molecular dynamics and quantum mechanical techniques are developed based on the experimental and chemistry synthesis. This book is of great interest for graduate students, researchers and health professionals interested in acquiring a better understanding of the mechanisms of medical treatments. In addition, it provides numerous tools to develop better therapies for human diseases.
Advances in Chemical Biology- An Insight to New Applications and Developments Volume – 1 by Dr. Sharangouda J. Patil,,Dr. Sadashiv S. O.,Dr. Nandeshwarappa B. Pdf
Advancesin chemical and biological sciences are together contributing as organic molecules by the natural or synthetic sources with the research insight of scientific touch to make it as innovative ideas, process, protocols, products, and technologies for industrial applications. These conceptualapplications are useful to determine the next generation organic molecules againstcardiovascular, degenerative, infectious, neurological diseases with the valid dataneeded to prove its technical efficiency by the comparing standard drugs. Emerging any drugs from the origin of organic drugs are having more importance in the industries due to their efficacyand target to regulate or recover the health issues, these novel drugs may be inthe form of enzymes, metabolites, proteins, hormones or call it as biologicallyderived organic molecules. Most of the organic molecule findings are used toanalyze their hypotheses, mechanism of action, experimental design and theirbiological properties to derive functional aspects. To know these molecules structuralconfiguration various techniques and technology used and it is essential to becharacterizing the molecule by the chromatography, spectroscopy, etc., to confirmand further biological studies to know the properties. In this context this editedcomprehensive book brings the current innovation in the organic molecules withthe updates of various biological applications and covering the area of agriculture,biotechnology, microbiology, neutraceutics, nanotechnology, pharmacology, synthetic medicinal chemistry etc., based applicative research data to reviewed extensivelyin narrative loom. Highlights of the chapters are novel experimental protocol, methodology, techniques, study concepts, used advanced tools and statistical analysisfor the use of organic molecules to know their biological properties. The book possessing 9 chapters covering chemistry and biological investigations on theorganic molecules with the updated innovative findings, principles of the molecules,molecular targets, also interactions with cell lines, microorganisms and animalmodels which persuade remedial measures as preclinical and clinical studies. Book also focused on types of synthesis, advanced extractions, use of analyticaltools, purification schemes, characterization methods and data analytics.It is a designed as comprehensive reference book for all the grade &level of researchersto use it as experimental handbook or manual to work on the similar areas, it isalso useful for the creative scholars to obtain research experience and enhancethe skills by updating themselves as need of hour, also know the timely outbreaksto combat by such organic molecules as emerging drugs to be in a bio-innovationforum.
