Why Asthma Is Not A Lung Disease

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Asthma and COPD

Peter J. Barnes,Jeffrey M. Drazen,Stephen I. Rennard,Neil C. Thomson

Author : Peter J. Barnes,Jeffrey M. Drazen,Stephen I. Rennard,Neil C. Thomson
Publisher : Elsevier
Page : 897 pages
File Size : 55,8 Mb
Release : 2009-03-19
Category : Medical
ISBN : 9780080920603

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Asthma and COPD by Peter J. Barnes,Jeffrey M. Drazen,Stephen I. Rennard,Neil C. Thomson Pdf

The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. * Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management * Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD * Most extensive reference to primary literature on both Asthma and COPD in one source. * Easy-to-read summaries of the latest advances alongside clear illustrations

Why Asthma is Not a Lung Disease

Daniel Ares

Author : Daniel Ares
Publisher : Page Publishing Inc
Page : 167 pages
File Size : 42,6 Mb
Release : 2019-03-11
Category : Philosophy
ISBN : 9781644241653

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Why Asthma is Not a Lung Disease by Daniel Ares Pdf

Just a short while back, I was dysfunctional. I needed a walker around the house. I couldn't bend. I could barely move. Short of my eighties, I now "knew" what it was like being near the end, near dying. When you are old, the idea of dying is a frequent visitor. I was wrong. Whatever was wrong with me is today also wrong with much younger people. The modern world does not do us favors in some ways, I have learned--and it is human ingenuity at fault. I am writing about that too, among other things. Some of the subjects discussed in this book in lay language: Asthma Allergies Digestion Back pains Skin issues Acid Reflux Sleep Apnea Autoimmunity Fungal infection Perhaps the information in this book will also help you, your loved one, or a friend, back to better health and functionality.

Airway Remodeling

Peter Howarth,John William Wilson,Jean Bousquet,Sabina Rak,Romain Pauwels

Author : Peter Howarth,John William Wilson,Jean Bousquet,Sabina Rak,Romain Pauwels
Publisher : CRC Press
Page : 328 pages
File Size : 50,7 Mb
Release : 2001
Category : MEDICAL
ISBN : 0429132581

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Airway Remodeling by Peter Howarth,John William Wilson,Jean Bousquet,Sabina Rak,Romain Pauwels Pdf

This landmark volume discusses the characteristics and impact of the remodeling process on airway function and clinical disease expression within the airway in asthma, covering pharmacological therapies and possible future targets relevant to regulating the remodeling process. Emphasizes the importance of treating underlying airway inflammation and the relevance of structural alterations to the airway wall, including glandular increases, enhanced collagen deposition within the submucosa, increased vasculature, smooth hypertrophy, and hyperplasias! Tracing the development and maintenance of bronchial hyperresponsiveness, decline in lung function, and loss of reversibility evident in chronic asthma, Airway Remodelingdescribes the contribution of inflammatory cells in the development of airway structural changes examines how pharmaceutical agents act and whether existing treatments modify or prevent remodeling in chronically inflamed asthmatic airways considers whether neural pathways initiate as well as contribute to the airway inflammatory cascade that leads to remodeling reviews the action of cytokines and growth factors on ASM signaling outlines novel approaches to regulating smooth muscle growth clarifies whether permanent ventilatory incapacity in asthma is caused by the uncoupling of the airway and the role of the lung parenchyma details high-resolution computerized tomography scan to measure the internal size of the airway at baseline, during challenge, or after bronchodilatation and more!Improving lung function and quality of life by reducing the need for emergency care, hospital admissions, and systemic steroid administration, Airway Remodeling is a superb reference for pulmonologists and respiratory system specialists; physiologists; pneumologists; allergists; pharmacologists; molecular, cellular, and lung biologists; and graduate and medical school students in these disciplines.

Disease Control Priorities in Developing Countries

Dean T. Jamison,Joel G. Breman,Anthony R. Measham,George Alleyne,Mariam Claeson,David B. Evans,Prabhat Jha,Anne Mills,Philip Musgrove

Author : Dean T. Jamison,Joel G. Breman,Anthony R. Measham,George Alleyne,Mariam Claeson,David B. Evans,Prabhat Jha,Anne Mills,Philip Musgrove
Publisher : World Bank Publications
Page : 1449 pages
File Size : 49,8 Mb
Release : 2006-04-02
Category : Medical
ISBN : 9780821361801

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Disease Control Priorities in Developing Countries by Dean T. Jamison,Joel G. Breman,Anthony R. Measham,George Alleyne,Mariam Claeson,David B. Evans,Prabhat Jha,Anne Mills,Philip Musgrove Pdf

Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.

How Tobacco Smoke Causes Disease

Anonim

Author : Anonim
Publisher : Unknown
Page : 728 pages
File Size : 50,7 Mb
Release : 2010
Category : Government publications
ISBN : UCSD:31822037817723

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How Tobacco Smoke Causes Disease by Anonim Pdf

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases

Institute of Medicine,Board on Population Health and Public Health Practice,Committee on a National Surveillance System for Cardiovascular and Select Chronic Diseases

Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee on a National Surveillance System for Cardiovascular and Select Chronic Diseases
Publisher : National Academies Press
Page : 200 pages
File Size : 40,6 Mb
Release : 2011-08-26
Category : Medical
ISBN : 9780309212199

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A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases by Institute of Medicine,Board on Population Health and Public Health Practice,Committee on a National Surveillance System for Cardiovascular and Select Chronic Diseases Pdf

Chronic diseases are common and costly, yet they are also among the most preventable health problems. Comprehensive and accurate disease surveillance systems are needed to implement successful efforts which will reduce the burden of chronic diseases on the U.S. population. A number of sources of surveillance data--including population surveys, cohort studies, disease registries, administrative health data, and vital statistics--contribute critical information about chronic disease. But no central surveillance system provides the information needed to analyze how chronic disease impacts the U.S. population, to identify public health priorities, or to track the progress of preventive efforts. A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases outlines a conceptual framework for building a national chronic disease surveillance system focused primarily on cardiovascular and chronic lung diseases. This system should be capable of providing data on disparities in incidence and prevalence of the diseases by race, ethnicity, socioeconomic status, and geographic region, along with data on disease risk factors, clinical care delivery, and functional health outcomes. This coordinated surveillance system is needed to integrate and expand existing information across the multiple levels of decision making in order to generate actionable, timely knowledge for a range of stakeholders at the local, state or regional, and national levels. The recommendations presented in A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases focus on data collection, resource allocation, monitoring activities, and implementation. The report also recommends that systems evolve along with new knowledge about emerging risk factors, advancing technologies, and new understanding of the basis for disease. This report will inform decision-making among federal health agencies, especially the Department of Health and Human Services; public health and clinical practitioners; non-governmental organizations; and policy makers, among others.

Pocket Book of Hospital Care for Children

World Health Organization

Author : World Health Organization
Publisher : World Health Organization
Page : 442 pages
File Size : 46,5 Mb
Release : 2013
Category : Medical
ISBN : 9789241548373

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Pocket Book of Hospital Care for Children by World Health Organization Pdf

The Pocket Book is for use by doctors nurses and other health workers who are responsible for the care of young children at the first level referral hospitals. This second edition is based on evidence from several WHO updated and published clinical guidelines. It is for use in both inpatient and outpatient care in small hospitals with basic laboratory facilities and essential medicines. In some settings these guidelines can be used in any facilities where sick children are admitted for inpatient care. The Pocket Book is one of a series of documents and tools that support the Integrated Managem.

Severe Asthma

Kian Fan Chung,Elliot Israel,Peter G. Gibson

Author : Kian Fan Chung,Elliot Israel,Peter G. Gibson
Publisher : European Respiratory Society
Page : 360 pages
File Size : 52,9 Mb
Release : 2019-06-01
Category : Medical
ISBN : 9781849841047

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Severe Asthma by Kian Fan Chung,Elliot Israel,Peter G. Gibson Pdf

Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.

Asthma, Health and Society

Andrew Harver,Harry Kotses

Author : Andrew Harver,Harry Kotses
Publisher : Springer Science & Business Media
Page : 347 pages
File Size : 54,7 Mb
Release : 2010-03-10
Category : Medical
ISBN : 9780387782850

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Asthma, Health and Society by Andrew Harver,Harry Kotses Pdf

Asthma, Health, and Society A Public Health Perspective Edited by Andrew Harver, University of North Carolina at Charlotte, Charlotte Harry Kotses, Ohio University, Athens Asthma, Health, and Society is a comprehensive, current resource on this complex disease—its scope, human costs, and management—from a combined social ecology/public health perspective. This important and unique book proposes a concerted, multifaceted response and sets out the foundation for shaping this response, comprising individual and large-scale assessment, education, advocacy, and multiple forms of intervention. In clear, authoritative detail enhanced by figures, graphs, and references, contributors explain where universal standards need to be set, alliances need to be built (such as among agencies and institutions in a community), and what is currently known about: Pathophysiology, epidemiology, and social impact of asthma. Genetic and environmental factors; protective factors and risk markers. Effects in women, minorities, children, teens, and elders. Medical management, self-management, and home monitoring. Evidence-based interventions at the family, school, and community levels. Screening guidelines, compliance issues, and more. In the absence of a cure or clear-cut causes, Asthma, Health, and Society offers the most robust compilation of practical knowledge on its subject to benefit the range of public health and asthma professionals, researchers, teachers, and students

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems

Kamal Dua,Philip M. Hansbro,Ridhima Wadhwa,Mehra Haghi,Lisa G. Pont,Kylie A. Williams

Author : Kamal Dua,Philip M. Hansbro,Ridhima Wadhwa,Mehra Haghi,Lisa G. Pont,Kylie A. Williams
Publisher : Academic Press
Page : 620 pages
File Size : 43,6 Mb
Release : 2020-08-04
Category : Technology & Engineering
ISBN : 9780128208885

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Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems by Kamal Dua,Philip M. Hansbro,Ridhima Wadhwa,Mehra Haghi,Lisa G. Pont,Kylie A. Williams Pdf

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development. Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)

The Health Effects of Cannabis and Cannabinoids

National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda
Publisher : National Academies Press
Page : 487 pages
File Size : 45,9 Mb
Release : 2017-03-31
Category : Science
ISBN : 9780309453073

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The Health Effects of Cannabis and Cannabinoids by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda Pdf

Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease

Venkataramana K Sidhaye,Michael Koval

Author : Venkataramana K Sidhaye,Michael Koval
Publisher : Academic Press
Page : 276 pages
File Size : 55,8 Mb
Release : 2017-03-09
Category : Medical
ISBN : 9780128038819

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Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease by Venkataramana K Sidhaye,Michael Koval Pdf

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. Provides a single source of information on lung epithelial junctions and transporters Discusses of the role of the epithelium in lung homeostasis and disease Includes capsule summaries of main conclusions as well as highlights of future directions in the field Covers the mechanistic basis for lung disease for a range of audiences

Asthma, COPD, and Overlap

Jonathan A. Bernstein,Louis-Philippe Boulet,Michael E. Wechsler, MD,MMSc

Author : Jonathan A. Bernstein,Louis-Philippe Boulet,Michael E. Wechsler, MD,MMSc
Publisher : CRC Press
Page : 290 pages
File Size : 53,7 Mb
Release : 2018-03-22
Category : Medical
ISBN : 9780429765186

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Asthma, COPD, and Overlap by Jonathan A. Bernstein,Louis-Philippe Boulet,Michael E. Wechsler, MD,MMSc Pdf

Using illustrative case examples, this book thoroughly reviews similarities and differences between asthma, chronic obstructive pulmonary disease (COPD) and the overlap syndrome. It is important to highlight the distinctions because these commonly encountered conditions in respiratory and primary care share many similarities but have important differences often mistaken for each other. This can have serious implications for treatment, particularly as new treatments are targeted at specific phenotypes of the diseases. This practical guide shows how to distinguish between the diseases on a pathological and clinical basis so that appropriate management and treatment may be pursued.

Disease Control Priorities, Third Edition (Volume 5)

Dorairaj Prabhakaran,Shuchi Anand,Thomas A. Gaziano,Jean-Claude Mbanya,Rachel Nugent

Author : Dorairaj Prabhakaran,Shuchi Anand,Thomas A. Gaziano,Jean-Claude Mbanya,Rachel Nugent
Publisher : World Bank Publications
Page : 466 pages
File Size : 41,9 Mb
Release : 2017-11-17
Category : Medical
ISBN : 9781464805202

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Disease Control Priorities, Third Edition (Volume 5) by Dorairaj Prabhakaran,Shuchi Anand,Thomas A. Gaziano,Jean-Claude Mbanya,Rachel Nugent Pdf

Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

Clinical Methods

Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst

Author : Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst
Publisher : Butterworth-Heinemann
Page : 1128 pages
File Size : 54,7 Mb
Release : 1990
Category : Medical
ISBN : MINN:31951D00416688Z

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Clinical Methods by Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst Pdf

A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR

Why Asthma Is Not A Lung Disease

Asthma and COPD by Peter J. Barnes,Jeffrey M. Drazen,Stephen I. Rennard,Neil C. Thomson Pdf

Why Asthma is Not a Lung Disease by Daniel Ares Pdf

Airway Remodeling by Peter Howarth,John William Wilson,Jean Bousquet,Sabina Rak,Romain Pauwels Pdf

Disease Control Priorities in Developing Countries by Dean T. Jamison,Joel G. Breman,Anthony R. Measham,George Alleyne,Mariam Claeson,David B. Evans,Prabhat Jha,Anne Mills,Philip Musgrove Pdf

How Tobacco Smoke Causes Disease by Anonim Pdf

A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases by Institute of Medicine,Board on Population Health and Public Health Practice,Committee on a National Surveillance System for Cardiovascular and Select Chronic Diseases Pdf

Pocket Book of Hospital Care for Children by World Health Organization Pdf

Severe Asthma by Kian Fan Chung,Elliot Israel,Peter G. Gibson Pdf

Asthma, Health and Society by Andrew Harver,Harry Kotses Pdf

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems by Kamal Dua,Philip M. Hansbro,Ridhima Wadhwa,Mehra Haghi,Lisa G. Pont,Kylie A. Williams Pdf

The Health Effects of Cannabis and Cannabinoids by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda Pdf

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease by Venkataramana K Sidhaye,Michael Koval Pdf

Asthma, COPD, and Overlap by Jonathan A. Bernstein,Louis-Philippe Boulet,Michael E. Wechsler, MD,MMSc Pdf

Disease Control Priorities, Third Edition (Volume 5) by Dorairaj Prabhakaran,Shuchi Anand,Thomas A. Gaziano,Jean-Claude Mbanya,Rachel Nugent Pdf

Clinical Methods by Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst Pdf

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