Zebrafish Model For Biomedical Research

Author : Prasan R. Bhandari,Kala Kumar Bharani,Amit Khurana
Publisher : Springer Nature
Page : 493 pages
File Size : 44,8 Mb
Release : 2022-05-30
Category : Medical
ISBN : 9789811652172

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Zebrafish Model for Biomedical Research by Prasan R. Bhandari,Kala Kumar Bharani,Amit Khurana Pdf

This book provides the latest information on the significance of zebrafish as an ideal model for researching the biomedical field, with references. This book also focused on the evidence of zebrafish as a model in cardiovascular, neurologic, psychiatric and metabolic research. In addition, the book also includes the research carried out on zebrafish in hepatic, renal, ophthalmic, and ENT related areas. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish models including specific research in the area of skin disorders, endocrine diseases, nutritional disorders, gastrointestinal, hematological disorders and cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and its suitability for modeling various diseases, providing a critical resource on the potential attributes of the zebrafish as a pharmacological model. In terms of scope, this book is a useful tool for young researchers, professors and pharmaceutical scientists for understanding the significance of zebrafish as an emerging pharmacological model that can significantly aid in the process of drug discovery and development.

Author : Samuel Cartner,Judith S. Eisen,Susan F. Farmer,Karen J. Guillemin,Michael L. Kent,George E. Sanders
Publisher : Academic Press
Page : 720 pages
File Size : 43,5 Mb
Release : 2019-11-22
Category : Science
ISBN : 9780128124321

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The Zebrafish in Biomedical Research by Samuel Cartner,Judith S. Eisen,Susan F. Farmer,Karen J. Guillemin,Michael L. Kent,George E. Sanders Pdf

The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications Includes the work of world-renowned authors Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series

Author : Yusuf Bozkurt
Publisher : Unknown
Page : 128 pages
File Size : 43,7 Mb
Release : 2020-03
Category : Electronic
ISBN : 1789859859

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Zebrafish in Biomedical Research by Yusuf Bozkurt Pdf

Author : Livia D'Angelo,Paolo de Girolamo
Publisher : Academic Press
Page : 476 pages
File Size : 44,5 Mb
Release : 2021-08-28
Category : Science
ISBN : 9780128212455

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Laboratory Fish in Biomedical Research by Livia D'Angelo,Paolo de Girolamo Pdf

Fish, and particularly zebrafish, have become the fastest-growing segment of the research population. They offer several advantages, in terms of biology and technologies to apply, and thus are employed in numerous research fields. Laboratory Fish in Biomedical Research: Biology, Husbandry and Research Applications for Zebrafish, Medaka, Killifish, Swordtail Fish, Cavefish, Stickleback, Goldfish and Danionella Translucida addresses the relevant and increasing need to collect cutting-edge knowledge on husbandry, maintenance, welfare and experimental protocols of the most common freshwater species under standard laboratory conditions. Provides husbandry and management protocols, devices and water systems Shows strength and weakness of breeding Explores potential scientific applications and experimental protocols. with regards to the most used freshwater fish used for scientific purposes

Author : P. Michael Conn
Publisher : Springer Science & Business Media
Page : 756 pages
File Size : 54,6 Mb
Release : 2008-03-07
Category : Medical
ISBN : 9781597452854

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Sourcebook of Models for Biomedical Research by P. Michael Conn Pdf

The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

Author : P. Michael Conn
Publisher : Springer Science & Business Media
Page : 756 pages
File Size : 47,9 Mb
Release : 2008
Category : Medical
ISBN : 9781588299338

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Sourcebook of Models for Biomedical Research by P. Michael Conn Pdf

The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.

Author : Allan V. Kalueff
Publisher : Springer
Page : 327 pages
File Size : 54,7 Mb
Release : 2017-02-06
Category : Medical
ISBN : 9783319337746

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The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish by Allan V. Kalueff Pdf

Animal models and tests have become increasingly important for biomedical research, enabling a better understanding of pathogenic pathways involved in various human disorders. Over the last decades, zebrafish (Danio rerio) have become a very popular model organism in biomedical research. Recently, this fish has entered the waters of neuroscience and biological psychiatry, quickly becoming an indispensable model species in this field. With a high genetic homology to humans (~75% based on coding regions), it is not surprising that humans and fish are very similar physiologically (and behaviorally). Therefore, it should not come as a surprise that zebrafish can be an excellent model of human neuropsychiatric disorders. While some classical psychiatrists may not too easily be persuaded by this generalization, the current book “The rights and wrongs of zebrafish: principles of behavioral phenotyping and CNS disease modeling” explains, in a domain-by-domain manner, how exactly zebrafish models can be used to target a wide range of human brain disorders and aberrant phenotypes. The contributors to this book are leading international scholars whose work spearheads innovative zebrafish neuroscience research around the world. Written by top experts in the field, this book makes for a useful, balanced and up-to-date reading that outlines the use of zebrafish to study the pathological mechanisms underlying neuropsychiatric disorders.

Author : James A Marrs,Swapnalee Sarmah
Publisher : Mdpi AG
Page : 0 pages
File Size : 43,7 Mb
Release : 2022-10-11
Category : Electronic
ISBN : 3036554599

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Zebrafish Models for Development and Disease 2.0 by James A Marrs,Swapnalee Sarmah Pdf

The special issue (Zebrafish Models for Development and Disease 2.0) is a collection of articles highlighting research using the zebrafish (Danio rerio) experimental organism. Research described in this special issue addresses various developmental biology, genetic, biomedical and neuroscience topics that should be of general interest to the biomedical research community.

Author : Allan V. Kalueff, Laporte,Adam Michael Stewart
Publisher : Humana Press
Page : 376 pages
File Size : 51,9 Mb
Release : 2016-05-01
Category : Medical
ISBN : 1493960024

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Zebrafish Protocols for Neurobehavioral Research by Allan V. Kalueff, Laporte,Adam Michael Stewart Pdf

Zebrafish play an integral role in biomedical research, enabling scientists to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. Written by experts, this volume sets out protocols for both larval and adult models.

Author : Hajime Kojima,Troy Seidle,Horst Spielmann
Publisher : Springer
Page : 130 pages
File Size : 46,7 Mb
Release : 2018-12-27
Category : Medical
ISBN : 9789811324475

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Alternatives to Animal Testing by Hajime Kojima,Troy Seidle,Horst Spielmann Pdf

This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.

Author : National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology
Publisher : National Academies Press
Page : 348 pages
File Size : 48,6 Mb
Release : 2000-12-21
Category : Nature
ISBN : 9780309070867

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Scientific Frontiers in Developmental Toxicology and Risk Assessment by National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology Pdf

Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

Author : James A. Marrs,Swapnalee Sarmah
Publisher : Unknown
Page : 0 pages
File Size : 52,7 Mb
Release : 2022
Category : Electronic
ISBN : 3036554602

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Zebrafish Models for Development and Disease 2.0 by James A. Marrs,Swapnalee Sarmah Pdf

The special issue (Zebrafish Models for Development and Disease 2.0) is a collection of articles highlighting research using the zebrafish (Danio rerio) experimental organism. Research described in this special issue addresses various developmental biology, genetic, biomedical and neuroscience topics that should be of general interest to the biomedical research community.

Author : Songlin Zhuang,Gefei Zhang,Dongxu Lei,Xinghu Yu,Mingsi Tong,Weiyang Lin,Yang Shi,Huijun Gao
Publisher : Springer Nature
Page : 265 pages
File Size : 46,9 Mb
Release : 2023-07-22
Category : Technology & Engineering
ISBN : 9783031334108

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Robotic Micromanipulation of Zebrafish Larva by Songlin Zhuang,Gefei Zhang,Dongxu Lei,Xinghu Yu,Mingsi Tong,Weiyang Lin,Yang Shi,Huijun Gao Pdf

This book offers readers a series of robotic methods for manipulating zebrafish larva, one of the most popular model vertebrates widely used in biomedical research and clinical applications. The authors leverage advanced control theories, image processing algorithms, and artificial intelligence to establish a robot-assisted automated or semi-automated zebrafish larva-targeted micromanipulation system for different experimental purposes. The methods presented are generic and can be translated to manipulate other types of biological objects, such as embryos or cells. Coverage includes topics that span the procedures of manipulating zebrafish larva, such as in-plane positioning, three-dimensional orientation, deformation-controllable immobilization, organ-targeted microinjection, whole-organism imaging, and high-throughput trajectory tracking of zebrafish larvae group movement. Robotic Micromanipulation of Zebrafish Larva is written in a simple, clear, and easy-to-read style. It is an ideal reference for academic researchers and biomedical operators. It is also a valuable resource for students learning robotics, control and system theories, image processing, artificial intelligence, and biomedical engineering.

Author : Morteza Jalali,Francesca Yvonne Louise Saldanha,Mehdi Jalali
Publisher : Academic Press
Page : 382 pages
File Size : 50,5 Mb
Release : 2017-03-31
Category : Science
ISBN : 9780128030783

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Basic Science Methods for Clinical Researchers by Morteza Jalali,Francesca Yvonne Louise Saldanha,Mehdi Jalali Pdf

Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow’s clinician scientists and future leaders in discovery science. Serves as a helpful guide for clinical researchers who lack a conventional science background Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)

Author : Claudia Harper,Christian Lawrence
Publisher : CRC Press
Page : 260 pages
File Size : 48,7 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781439807446

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The Laboratory Zebrafish by Claudia Harper,Christian Lawrence Pdf

Like other books in the Laboratory Animal Pocket Reference Series, this guide covers all aspects pertaining to the use of these organisms including their basic biology, humane care and management, husbandry, life support systems, regulatory compliance, technical procedures, veterinary care, and water quality management. In the relatively brief span