2020 Pathways

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Pathways of Reconciliation

Author : Aimée Craft,Paulette Regan
Publisher : Univ. of Manitoba Press
Page : 394 pages
File Size : 40,5 Mb
Release : 2020-05-29
Category : Political Science
ISBN : 9780887558559

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Pathways of Reconciliation by Aimée Craft,Paulette Regan Pdf

Since the Truth and Reconciliation Commission released its Calls to Action in June 2015, governments, churches, non-profit, professional and community organizations, corporations, schools and universities, clubs and individuals have asked: “How can I/we participate in reconciliation?” Recognizing that reconciliation is not only an ultimate goal, but a decolonizing process of journeying in ways that embody everyday acts of resistance, resurgence, and solidarity, coupled with renewed commitments to justice, dialogue, and relationship-building, Pathways of Reconciliation helps readers find their way forward. The essays in Pathways of Reconciliation address the themes of reframing, learning and healing, researching, and living. They engage with different approaches to reconciliation (within a variety of reconciliation frameworks, either explicit or implicit) and illustrate the complexities of the reconciliation process itself. They canvass multiple and varied pathways of reconciliation, from Indigenous and non-Indigenous perspectives, reflecting a diversity of approaches to the mandate given to all Canadians by the TRC with its Calls to Action. Together the authors — academics, practitioners, students and ordinary citizens — demonstrate the importance of trying and learning from new and creative approaches to thinking about and practicing reconciliation and reflect on what they have learned from their attempts (both successful and less successful) in the process.

Cycling Pathways

Author : DEKKER
Publisher : Unknown
Page : 128 pages
File Size : 41,9 Mb
Release : 2021-10-21
Category : Electronic
ISBN : 9463728473

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Cycling Pathways by DEKKER Pdf

1. The long time scale (1880-2020). Most works only focus on a few decades, while this book takes a longer perspective allowing me to analyze the way policy choices in the 1920s still shape current mobility for instance. 2. The exploration of archives that have not been used before to study cycling history. 3. The focus on social movements as well as provincial and national policymakers and engineers where previous cycling historiography tends to focus only on urban politics.

The sustainability series: The plastics problem - pathways towards sustainable solutions against plastic pollution

Author : Tomaso Fortibuoni,Jenna Jambeck,Britta Denise Hardesty,Anna Maria Addamo,Oihane C. Basurko,Mahua Saha
Publisher : Frontiers Media SA
Page : 162 pages
File Size : 51,9 Mb
Release : 2023-07-20
Category : Science
ISBN : 9782832529331

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The sustainability series: The plastics problem - pathways towards sustainable solutions against plastic pollution by Tomaso Fortibuoni,Jenna Jambeck,Britta Denise Hardesty,Anna Maria Addamo,Oihane C. Basurko,Mahua Saha Pdf

New Roles of Autophagy Pathways in Cancer

Author : Daniel Hector Grasso,Eugenia Morselli,Waleska Kerllen Martins,Claudio Marcelo Fader
Publisher : Frontiers Media SA
Page : 369 pages
File Size : 52,8 Mb
Release : 2021-09-10
Category : Science
ISBN : 9782889712816

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New Roles of Autophagy Pathways in Cancer by Daniel Hector Grasso,Eugenia Morselli,Waleska Kerllen Martins,Claudio Marcelo Fader Pdf

Cancer Stem Cell Markers and Related Network Pathways

Author : Shihori Tanabe
Publisher : Springer Nature
Page : 163 pages
File Size : 48,6 Mb
Release : 2023-02-02
Category : Medical
ISBN : 9783031129742

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Cancer Stem Cell Markers and Related Network Pathways by Shihori Tanabe Pdf

This book entitled “Cancer Stem Cell Markers and Related Network Path-ways” is about cancer stem cell (CSC) markers and the molecular network pathways. CSCs play an important role in the cancer drug resistance, metastasis and recurrence. Epithelial-mesenchymal transition (EMT) is closely related to CSC phenotype. This book covers various aspects of the molecular networks related to CSCs including the important phenotypic change such as EMT. Readers will discover the importance of the identification of CSC markers and EMT-related molecules in CSC network pathways. The CSC signaling pathways and EMT molecular network pathways attract researchers in the field to define the cancer therapeutic targets. Cancer environment is important in the acquisition of CSC phenotype in cells. The revealing of this CSC mystery is across 7 chapters. The topic of this book is particularly relevant to research in the field of cancer and stem cells, as well as the network pathways. We hope that this book helps the readers to be interested in understanding why the CSC concept is important and attractive.

Cancer Stem Cells and Signaling Pathways

Author : Surajit Pathak,Antara Banerjee
Publisher : Elsevier
Page : 703 pages
File Size : 55,8 Mb
Release : 2023-11-14
Category : Science
ISBN : 9780443132117

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Cancer Stem Cells and Signaling Pathways by Surajit Pathak,Antara Banerjee Pdf

Cancer Stem Cells and Signaling Pathways explores the mechanism of cancer stem cell signaling pathways in cancer advancement, serving as an ideal reference guide for investigators with valuable answers to problems associated with anti-cancer treatments and an understanding of the crosstalk among the signaling pathways in CSC regulation. Despite recent advances in tumor therapy and a greater understanding of their biology, tumors continue to be a prevalent and fatal worldwide. According to a novel paradigm in tumor biology, a small percentage of the cells within a tumor known as cancer stem cells (CSCs) are predicted as a crucial population for tumor progression. Presents cancer stem characteristics and their signaling pathways Highlights the use of animal models for cancer research, the use of genetically modified stem cells to deliver antitumor agents, and the significance of stem cell signaling in drug discovery Covers basic and translational research appropriate for scientists and clinicians exploring alternative treatments for various cancers

Inflammatory Tumor Immune Microenvironment: Molecular Mechanisms and Signaling Pathways in Cancer Progression and Metastasis

Author : Xu Wang,Tengchuan Jin,Christopher James Pirozzi,Xueli Zhang,Shu-Heng Jiang
Publisher : Frontiers Media SA
Page : 448 pages
File Size : 48,7 Mb
Release : 2022-03-25
Category : Medical
ISBN : 9782889747542

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Inflammatory Tumor Immune Microenvironment: Molecular Mechanisms and Signaling Pathways in Cancer Progression and Metastasis by Xu Wang,Tengchuan Jin,Christopher James Pirozzi,Xueli Zhang,Shu-Heng Jiang Pdf

Cytokines, Novel Cell Death Models and Pathways in Cardiovascular Diseases

Author : Yuli Huang,Ruofeng Qiu,Hai-Feng Zhang,Yunzhao Hu,Weiyi Mai
Publisher : Frontiers Media SA
Page : 98 pages
File Size : 45,6 Mb
Release : 2023-09-26
Category : Medical
ISBN : 9782832534410

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Cytokines, Novel Cell Death Models and Pathways in Cardiovascular Diseases by Yuli Huang,Ruofeng Qiu,Hai-Feng Zhang,Yunzhao Hu,Weiyi Mai Pdf

Cytokines are soluble proteins secreted by a wide variety of cells in the body, playing crucial roles in many physiological responses and are involved in the pathophysiology of cardiovascular diseases (CVDs). Recently, there is great progress in discoveries that some novel cytokines, including secreted frizzled-related proteins (SFRPs), adiponectin, and C1q/TNF-Related Proteins (CTRPs), can perform a protective effect in cardiometabolic diseases, heart failure and coronary heart disease. However, the mechanisms underlying the molecular and pathophysiological actions of these cytokines in CVDs are still vague. Novel mechanisms of cell death including pyroptosis, autophagy, ferroptosis, cuproptosis, and PANoptosis have been considered novel therapeutic targets for CVDs. Some cytokines have been shown to regulate the cell death pathway in the incidence and development of CVDs. Further investigations are needed to understand the link between these novel cytokines and novel cell death models and pathways in CVDs.

Pathways to a Successful Accountable Care Organization

Author : Peter A. Gross
Publisher : JHU Press
Page : 343 pages
File Size : 43,6 Mb
Release : 2020-08-18
Category : Medical
ISBN : 9781421438269

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Pathways to a Successful Accountable Care Organization by Peter A. Gross Pdf

A valuable guide to starting and running a successful accountable care organization. Health care in America is undergoing great change. Soon, accountable care organizations—health care organizations that tie provider reimbursements to quality metrics and reductions in the cost of care—will be ubiquitous. But how do you set up an ACO? How does an ACO function? And what are the keys to creating a profitable ACO? Pathways to a Successful Accountable Care Organization will help guide you through the complicated process of establishing and running an ACO. Peter A. Gross, MD, who has firsthand experience as the chairman of a successful ACO, breaks down how he did it and describes the pitfalls he discovered along the way. In-depth essays by a group of expert authors touch on • the essential ingredients of a successful ACO • monitoring and submitting Group Practice Reporting Option quality measures • mastering your patients' responses to the Consumer Assessment of Health Plans Survey • how bundled payments and CPC+ can meld with your ACO • how MACRA and MIPS affect your ACO • the role of an ACO/CIN • the complexities of post-acute care • data analytics • engaging and integrating physician practices Dr. Gross and his colleagues are in a perfect position to guide other health care leaders through the ACO process while also providing excellent case studies for policy professionals who are interested in how their work influences health care delivery. Readers will come away with the necessary knowledge to thrive and be rewarded with cost savings. Contributors: Joshua Bennett, Allison Brennan, Glen Champlin, Kris Corwin, Guy D'Andrea, Joseph F. Damore, Mitchel Easton, Andy Edeburn, Seth Edwards, Jennifer Gasperini, Kris Gates, Shawn Griffin, Peter A. Gross, Brent Hardaway, Mark Hiller, Beth Ireton, Thomas Kloos, Jeremy Mathis, Miriam McKisic, Morey Menacker, Denise Patriaco, Elyse Pegler, John Pitsikoulis, Michael Schweitzer, Bryan F. Smith

Epigenetic Regulation of Inflammatory Pathways in Cancer and Aging

Author : Deepavali Chakravarti,Chandrima Das,Lolitika Mandal
Publisher : Frontiers Media SA
Page : 148 pages
File Size : 51,7 Mb
Release : 2023-04-03
Category : Science
ISBN : 9782832519820

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Epigenetic Regulation of Inflammatory Pathways in Cancer and Aging by Deepavali Chakravarti,Chandrima Das,Lolitika Mandal Pdf

Autism Signaling Pathways

Author : Yu-Chih Lin,Yi-Ping Hsueh
Publisher : Frontiers Media SA
Page : 193 pages
File Size : 50,7 Mb
Release : 2021-11-23
Category : Science
ISBN : 9782889716579

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Autism Signaling Pathways by Yu-Chih Lin,Yi-Ping Hsueh Pdf

New Developments in Pathways Towards Diversity and Inclusion in STEM: A United States Perspective

Author : Alexander Gates,Juan Gilbert,Chris Botanga,Kim Nguyen,Bonita London
Publisher : Frontiers Media SA
Page : 273 pages
File Size : 54,9 Mb
Release : 2022-10-17
Category : Education
ISBN : 9782832505816

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New Developments in Pathways Towards Diversity and Inclusion in STEM: A United States Perspective by Alexander Gates,Juan Gilbert,Chris Botanga,Kim Nguyen,Bonita London Pdf

The Louis Stokes Alliances for Minority Participation (LSAMP) program of the US National Science Foundation has been a primary force for raising the success and graduation of minority students in STEM for 30 years. Increasing the number of underrepresented students earning baccalaureate degrees, and entering graduate school in STEM is the goal of LSAMP. This goal has been nearly achieved through the formation of alliances of degree granting institutions of higher learning, varying from community colleges to major research institutions. Currently there are 59 alliances including more than 400 institutions. LSAMP is responsible for more than 650,000 bachelor’s degrees earned by minority students in STEM. The papers for this Research Topic should focus on the use of LSAMP activities, programs and collaborations to develop pathways to success and graduation of STEM majors from minority groups that underrepresented in STEM. These pathways can include any segment from pre-college through graduate school. Areas of special interest include mentoring, research experiences, transitions between levels and novel approaches for retention. The studies should be research based and rigorous. They can be pure research studies, curriculum and design or literature reviews but they must be at a cutting edge level and be subject to detailed review and assessment.

Precision Cancer Therapies, Volume 1

Author : Stephen M. Ansell,John F. Seymour
Publisher : John Wiley & Sons
Page : 516 pages
File Size : 52,5 Mb
Release : 2023-06-06
Category : Medical
ISBN : 9781119819929

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Precision Cancer Therapies, Volume 1 by Stephen M. Ansell,John F. Seymour Pdf

A Thorough Compilation of the Many Scientific Breakthroughs in the Ongoing Development of Precision Cancer Therapies Related to Lymphoma Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice focuses on lymphoma, an area which has seen a remarkable number of breakthroughs in the ongoing development of precision cancer therapies. Each section on a specific biology or class of drugs has an introductory chapter written by an authority in the field, exclusively focused on the science and its relevance to cancer biology. This approach addresses the need for scientists, physicians, and the private sector to understand the broader context of the extraordinary advances that have produced such astonishing advances in the disease. The work primarily focuses on how to understand and translate fundamental principles of basic science into information that can be directly applied to patients – hence the subtitle, From Concept to Practice. To aid in readers’ comprehension, the first page of each chapter contains a box entitled ‘Take Home Points’. This short text will highlight the major unique points about the information contained within the chapter. Some of the key topics addressed in the work are as follows: Biological basis of the lymphoid malignancies: fundamental principles of lymphomagenesis and molecular classification of lymphoid malignancies Targeting programmed cell death: principles for understanding the many types of cell death and promising combinations of drugs targeting apoptosis Targeting the PI3K pathway: understanding the intricacies of this complex biology and precisely how targeted drugs can be leveraged therapeutically Targeting the cancer epigenome: pharmacologic features of drugs targeting the epigenome and future prospects for targeting various aspects of epigenetic control Targeting the tumour proteome: understanding the mechanisms of protein degradation in cancer including both older drugs like proteasome inhibitors, and newer PROTAC based approaches Written primarily for scientists and physicians in both the public and private sectors, Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignancies: From Concept to Practice is a comprehensive reference work for those interested in the growing area of Precision Cancer Therapies. Seamlessly integrating the basic and applied science, this volume will be an indispensable reference for those interested in translating the most important advances in science to innovative novel treatments for patients.

Oxidative Stress, Antioxidants, Transcription Factors, and Assimilation of Signal Transduction Pathways in Obesity-Related Disorders

Author : Terry D. Hinds, Jr,David E. Stec,Barbara Wegiel
Publisher : Frontiers Media SA
Page : 206 pages
File Size : 50,7 Mb
Release : 2021-10-21
Category : Science
ISBN : 9782889715275

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Oxidative Stress, Antioxidants, Transcription Factors, and Assimilation of Signal Transduction Pathways in Obesity-Related Disorders by Terry D. Hinds, Jr,David E. Stec,Barbara Wegiel Pdf

Topic Editors Terry Hinds and David Stec have submitted patents related to bilirubin and obesity related disorders. The other Topic Editor declare no potential conflicts of interest with regards to the Research Topic subject.

Targeting Signaling Pathways in Solid Tumors Part A

Author : Anonim
Publisher : Elsevier
Page : 276 pages
File Size : 44,8 Mb
Release : 2024-04-23
Category : Science
ISBN : 9780443235474

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Targeting Signaling Pathways in Solid Tumors Part A by Anonim Pdf

Targeting Signaling Pathways in Solid Tumors, Part A, Volume 385 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Drugging the Undruggable: Advances in Targeting KRAS Signaling in Solid Tumors, Emerging Trends in Gastrointestinal Cancers: Targeting Developmental Pathways in their Carcinogenesis and Tumor Progression, Importance of targeting various cell signaling pathways in solid cancers, Targeting signaling pathways in cancer stem cells: a potential approach for developing novel anticancer therapeutics, Factors affecting heterogeneity in breast cancer microenvironment: A narrative review, and much more. Additional sections cover Exploring TLR Signaling Pathways as Promising Targets in Cervical Cancer: The Road Less Travelled Provides the latest information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike