Antioxidants In Human Health And Disease

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Natural Antioxidants in Human Health and Disease

Balz Frei
Natural Antioxidants in Human Health and Disease Book PDF

Author : Balz Frei
Publisher : Academic Press
Page : 588 pages
File Size : 49,9 Mb
Release : 2012-12-02
Category : Technology & Engineering
ISBN : 9780080571683

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Natural Antioxidants in Human Health and Disease by Balz Frei Pdf

This book serves as a comprehensive overview of the current scientific knowledge on the health effects of dietary and supplemental antioxidants (such as vitamins C and E). Chapters integrate information from basic research and animal studies, epidemiologic studies, and clinical intervention trials. The popular media has taken great interest in antioxidants, with numerous articles emphasizing their role in preventing disease and the possible slowing of the aging process. These antioxidant vitamins may be important in preventing not only acute deficiency symptoms, but also chronic disorders such as heart disease and certain types of cancer. This book, therefore, is not only for scientists and doctors, but also for health writers, journalists, and informed lay people. The text focuses on several human conditions for which there is now good scientific evidence that oxidation is an important etiological component. Specifically, antioxidants may prevent or slow down the progression of: Cancer, Cardiovascular disease, Immune system disorders, Cataracts, Neurological disorders, Degeneration due to the aging process.

Oxidative Stress

Silvana Andreescu,Maria Hepel
Oxidative Stress Book PDF

Author : Silvana Andreescu,Maria Hepel
Publisher : ACS Symposium
Page : 0 pages
File Size : 41,7 Mb
Release : 2016-08
Category : Science
ISBN : 0841231001

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Oxidative Stress by Silvana Andreescu,Maria Hepel Pdf

This book provides a comprehensive overview of the oxidative stress related mechanisms in biological systems and the involvement of reactive oxygen and nitrogen species (ROS and RNS), the damage of DNA, proteins, and lipids caused by oxidative stress, the protection of cells and tissues against free radicals, the relation of the oxidative stress to aging and human diseases including cancer and neurological disorders, and the development of new therapeutic approaches to modulate oxidative stress. The current state-of-the-art methodologies including the development of sensors and biosensors for the detection of ROS/RNS and of biomarkers of oxidative stress are also discussed. The book is organized in three overlapping parts, starting with general considerations of the oxidative stress, homeostasis pathways, and ROS mechanisms, followed by chapters discussing the involvement of ROS in particular diseases and concluding with analytical aspects of oxidative stress monitoring. The book provides a solid background on oxidative stress and ROS/RNS generation for novice learners while also offering scientists and practitioners already involved in this field a wealth of information covering the most recent developments in the study of oxidative stress, the role of radical species, novel antioxidant therapies, and methods for assessing free radicals and oxidative stress.

Antioxidant Food Supplements in Human Health

Lester Packer,Midori Hiramatsu,Toshikazu Yoshikawa
Antioxidant Food Supplements in Human Health Book PDF

Author : Lester Packer,Midori Hiramatsu,Toshikazu Yoshikawa
Publisher : Elsevier
Page : 511 pages
File Size : 46,7 Mb
Release : 1999-03-16
Category : Technology & Engineering
ISBN : 0080527280

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Antioxidant Food Supplements in Human Health by Lester Packer,Midori Hiramatsu,Toshikazu Yoshikawa Pdf

Antioxidant Food Supplements in Human Health discusses new discoveries in the areas of oxygen and nitric oxide metabolism and pathophysiology, redox regulation and cell signaling, and the identification of natural antioxidants and their mechanisms of action on free radicals and their role in health and disease. An essential resource for researchers, students, and professionals in food science and nutrition, gerontology, physiology, pharmacology, and related areas. Health effects of antioxidant nutrients Nutrients of vitamins C and E, selenium, alpha-lipoic acid, coenzyme Q10, carotenoids, and flavonoids Natural source antioxidants, including pine bark, ginko biloba, wine, herbs,uyaku, and carica papaya

Polyphenols in Human Health and Disease

Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Polyphenols in Human Health and Disease Book PDF

Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Page : 470 pages
File Size : 49,7 Mb
Release : 2018-08-06
Category : Medical
ISBN : 9780128130070

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Polyphenols in Human Health and Disease by Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi Pdf

Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities. Expands coverage on green tea, cocoa, wine, cumin and herbs Outlines their chemical properties, bioavailability and metabolomics Provides a self-teaching guide to learn the mechanisms of action and health benefits of polyphenols

Free Radicals in Human Health and Disease

Vibha Rani,Umesh Chand Singh Yadav
Free Radicals in Human Health and Disease Book PDF

Author : Vibha Rani,Umesh Chand Singh Yadav
Publisher : Springer
Page : 430 pages
File Size : 42,5 Mb
Release : 2014-11-14
Category : Science
ISBN : 9788132220350

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Free Radicals in Human Health and Disease by Vibha Rani,Umesh Chand Singh Yadav Pdf

The role of oxidative stress in human disease has become an area of intense interest. Free radicals, a normal product of metabolism, exist in all aerobic cells in balance with biochemical antioxidants. Environmental stress increases the levels of free radicals drastically, thereby disturbing the equilibrium between free radical production and the antioxidant capability causing oxidative stress. Over the years, ROS has been implicated in the pathologies of various diseases like cancer, neurological disorder, cardiovascular diseases rheumatoid arthritis, diabetes etc. This book provides an in depth critical state-of-art reviews from established investigators on free radicals, ROS associated pathogenesis of human diseases, biomarkers of oxidative damage, antioxidants, phytonutrients and other related health concerns of modern society. The present book is aimed at graduate students, researchers in academia, industry and clinicians with the interest in redox biology. Special attention has been devoted to the topic of ROS signalling, oxidative stress induced human pathologies & antioxidative therapies. The book consists of four parts in specified topics based on the current literatures for the better understanding of the readers with respect to their subject-wise interests. The first section of the book provides an overview about the ROS production and their measuring tools and techniques followed by the mechanisms involved in the oxidative stress in the second section. The third section describes the involvement of oxidative stress in different human diseases and the last section focuses on the different strategies to ameliorate oxidative stress induced stress.

Antioxidants in Human Health and Disease

Nina Pegg
Antioxidants in Human Health and Disease Book PDF

Author : Nina Pegg
Publisher : Unknown
Page : 242 pages
File Size : 40,6 Mb
Release : 2020-09-15
Category : Medical
ISBN : 1632418312

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Antioxidants in Human Health and Disease by Nina Pegg Pdf

Living organisms require oxygen for survival, but it is also a highly reactive molecule that can damage organisms by producing reactive oxygen species. Oxidation is the chemical reaction that produces free radicals and thereby leads to chain reactions with the potential to damage the cells of organisms. Antioxidants inhibit oxidation. Ascorbic acid or thiols are antioxidants that can terminate these chain reactions. Organisms have a complex system of antioxidant metabolites and enzymes that work in tandem to prevent oxidative damage to DNA, proteins and lipids. However, reactive oxygen species have useful cellular functions as well, such as redox signaling. Antioxidant systems therefore do not remove oxidants completely but keep them at an optimum level. The role of oxidative stress in degenerative diseases, such as diabetes, kidney disease, neurological disorders, obesity, cancer and aging is understood. This makes antioxidant dietary supplements a potential strategy to overcome these conditions. This book provides comprehensive insights into antioxidants and their role in human health and disease. It will also provide interesting topics for research, which interested readers can take up. With state-of-the-art inputs by acclaimed experts of this field, this book targets students and professionals.

Antioxidants in Health and Disease

Antonis Zampelas,Renata Micha
Antioxidants in Health and Disease Book PDF

Author : Antonis Zampelas,Renata Micha
Publisher : CRC Press
Page : 340 pages
File Size : 48,7 Mb
Release : 2015-06-09
Category : Medical
ISBN : 9781466580114

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Antioxidants in Health and Disease by Antonis Zampelas,Renata Micha Pdf

Antioxidant use in health promotion and disease prevention either through dietary intake or supplementation is controversial. This book reviews the latest evidence-based research in the area, principally through prospective cohort studies and randomized controlled trials. It assesses major dietary antioxidants and discusses their use in diseases such as cancer, diabetes, stroke, coronary heart disease, HIV/AIDS, and neurodegenerative and immune diseases. The use of antioxidants in health is also discussed along with common adverse effects associated with antioxidant use.

Reactive Oxygen Species in Biology and Human Health

Shamim I. Ahmad
Reactive Oxygen Species in Biology and Human Health Book PDF

Author : Shamim I. Ahmad
Publisher : CRC Press
Page : 543 pages
File Size : 51,6 Mb
Release : 2017-12-19
Category : Science
ISBN : 9781498735469

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Reactive Oxygen Species in Biology and Human Health by Shamim I. Ahmad Pdf

Unlike other narrowly focused books, Reactive Oxygen Species in Biology and Human Health provides a comprehensive overview of ROS. It covers the current status of research and provides pointers to future research goals. Additionally, it authoritatively reviews the impact of reactive oxygen species with respect to various human diseases and discusses antioxidants and other compounds that counteract oxidative stress. Comprised of seven sections, the first section describes the introduction, detection, and production of ROS, emphasizing phenolic compounds and vitamin E for their abilities to act as antioxidants. This section also highlights the role of lipoprotein-associated oxidative stress. Section two addresses the importance of iron accumulation in the brain resulting in the development of a group of neurodegenerative disorders (NDs) and identifies several causative genes for neurodegeneration with brain iron accumulation (NBIA) associated with Parkinsonism-related disorders. The third section discusses a number of NDs, including amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD), Huntington's disease (HD), epilepsy, and multiple sclerosis (MS). Section four addresses autoimmune diseases caused by ROS, including asthma, autoimmune liver diseases, rheumatoid arthritis, thyroid disease, primary biliary cirrhosis, and systemic lupus. Section five analyzes a number of different cancers, including lung cancer, breast cancer, and melanoma, along with possible treatment regimens. Section six discusses cardiovascular diseases (CVDs) induced by ROS, presents the ROS-associated complex biochemical processes inducing inflammation as an important cause of CVDs, and explains the roles carotenoids play in preventing CVDs. The final section addresses other human diseases induced by oxidative stress, including sickle cell disease, nonalcoholic steatohepatitis, retinopathy, fibromyalgia, chronic obstructive pulmonary disease, asthma, pulmonary hypertension, infertility, and aging of human skin.

Nutritional Antioxidant Therapies: Treatments and Perspectives

Kaïs Hussain Al-Gubory,Ismail Laher
Nutritional Antioxidant Therapies Treatments and Perspectives Book PDF

Author : Kaïs Hussain Al-Gubory,Ismail Laher
Publisher : Springer
Page : 553 pages
File Size : 50,7 Mb
Release : 2018-03-10
Category : Medical
ISBN : 9783319676258

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Nutritional Antioxidant Therapies: Treatments and Perspectives by Kaïs Hussain Al-Gubory,Ismail Laher Pdf

This book offers a collection of expert reviews on the use of plant-based antioxidant therapies in disease prevention and treatment. Topics discussed include the uses of plant and nutritional antioxidants in the contexts of reproductive health and prenatal development, healthcare and aging, noncommunicable chronic diseases, and environmental pollution. The text is complemented by a wealth of color figures and summary tables.

Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids

Institute of Medicine,Food and Nutrition Board,Standing Committee on the Scientific Evaluation of Dietary Reference Intakes,Subcommittee on Interpretation and Uses of Dietary Reference Intakes,Subcommittee on Upper Reference Levels of Nutrients,Panel on Dietary Antioxidants and Related Compounds
Dietary Reference Intakes for Vitamin C Vitamin E Selenium and Carotenoids Book PDF

Author : Institute of Medicine,Food and Nutrition Board,Standing Committee on the Scientific Evaluation of Dietary Reference Intakes,Subcommittee on Interpretation and Uses of Dietary Reference Intakes,Subcommittee on Upper Reference Levels of Nutrients,Panel on Dietary Antioxidants and Related Compounds
Publisher : National Academies Press
Page : 530 pages
File Size : 51,5 Mb
Release : 2000-08-27
Category : Medical
ISBN : 9780309069496

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Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids by Institute of Medicine,Food and Nutrition Board,Standing Committee on the Scientific Evaluation of Dietary Reference Intakes,Subcommittee on Interpretation and Uses of Dietary Reference Intakes,Subcommittee on Upper Reference Levels of Nutrients,Panel on Dietary Antioxidants and Related Compounds Pdf

This volume is the newest release in the authoritative series of quantitative estimates of nutrient intakes to be used for planning and assessing diets for healthy people. Dietary Reference Intakes (DRIs) is the newest framework for an expanded approach developed by U.S. and Canadian scientists. This book discusses in detail the role of vitamin C, vitamin E, selenium, and the carotenoids in human physiology and health. For each nutrient the committee presents what is known about how it functions in the human body, which factors may affect how it works, and how the nutrient may be related to chronic disease. Dietary Reference Intakes provides reference intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for different groups based on age and gender, along with a new reference intake, the Tolerable Upper Intake Level (UL), designed to assist an individual in knowing how much is "too much" of a nutrient.

Omega-3 Fatty Acids

Mahabaleshwar V. Hegde,Anand Arvind Zanwar,Sharad P. Adekar
Omega 3 Fatty Acids Book PDF

Author : Mahabaleshwar V. Hegde,Anand Arvind Zanwar,Sharad P. Adekar
Publisher : Humana Press
Page : 610 pages
File Size : 40,6 Mb
Release : 2016-09-15
Category : Medical
ISBN : 9783319404585

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Omega-3 Fatty Acids by Mahabaleshwar V. Hegde,Anand Arvind Zanwar,Sharad P. Adekar Pdf

This volume argues for the importance of essential nutrients in our diet. Over the last two decades there has been an explosion of research on the relationship of Omega-3 fatty acids and the importance of antioxidants to human health. Expert authors discuss the importance of a diet rich in Omega-3 Fatty acids for successful human growth and development and for the prevention of disease. Chapters highlight their contribution to the prevention and amelioration of a wide range of conditions such as heart disease, diabetes, arthritis, cancer, obesity, mental health and bone health. An indispensable text designed for nutritionists, dietitians, clinicians and health related professionals, Omega-3 Fatty Acids: Keys to Nutritional Health presents a comprehensive assessment of the current knowledge about the nutritional effects of Omega-3 fatty acids and their delivery in foods.

Polyphenols in Human Health and Disease

Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Polyphenols in Human Health and Disease Book PDF

Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Page : 484 pages
File Size : 53,8 Mb
Release : 2018-08-06
Category : Medical
ISBN : 9780128130094

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Polyphenols in Human Health and Disease by Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi Pdf

Polyphenols in Prevention and Treatment of Human Disease, Second Edition authoritatively covers evidence of the powerful health benefits of polyphenols, touching on cardiovascular disease, cancer, obesity, diabetes and osteoporosis. This collection represents the contributions of an international group of experts in polyphenol research who share their expertise in endocrinology, public health, cardiology, pharmacology, agriculture and veterinary science. Researchers from diverse backgrounds will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted insights into the mechanisms of disease. This reference fills a void in research where nutritionists and alternative therapies may be applicable. Describes polyphenol modulation of blood flow and oxygenation as a potential mechanism of protection against vascular atherosclerosis Describes how polyphenols and antioxidants frequently change immune defenses and actions Focuses on the most important areas of research and provides insights into their relationships and translational opportunities

Polyphenols in Human Health and Disease

Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Polyphenols in Human Health and Disease Book PDF

Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Academic Press
Page : 1488 pages
File Size : 53,7 Mb
Release : 2013-10-26
Category : Science
ISBN : 9780123984678

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Polyphenols in Human Health and Disease by Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi Pdf

Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more. Explores neuronal protection by polyphenol metabolites and their application to medical care Defines modulation of enzyme actions to help researchers see and study polyphenols’ mechanisms of action, leading to clinical applications Includes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases

Plant Antioxidants and Health

Halina Maria Ekiert,Kishan Gopal Ramawat,Jaya Arora
Plant Antioxidants and Health Book PDF

Author : Halina Maria Ekiert,Kishan Gopal Ramawat,Jaya Arora
Publisher : Springer
Page : 861 pages
File Size : 54,8 Mb
Release : 2022-06-26
Category : Science
ISBN : 3030781593

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Plant Antioxidants and Health by Halina Maria Ekiert,Kishan Gopal Ramawat,Jaya Arora Pdf

This book provides a comprehensive reference guide to plant-derived antioxidants, their beneficial effects, mechanisms of action, and role in disease prevention and improving general health (anti-ageing effect). The content is divided into three main parts, the first of which covers various antioxidants (such as polyphenols, carotenoids, tocopherols, tocotrienols, glutathione, ascorbic acid), their origins, plant biochemistry and industrial utilization. In turn, the book’s second, main part focuses on antioxidants’ beneficial health effects, explains biochemical fundamentals such as the free radical theory and oxidative stress, and discusses antioxidants’ role in e.g. cancer, cardiovascular diseases, inflammation, degenerative diseases and ageing. The third part reviews general laboratory methods for antioxidant screening, preservation and determination. Written by an international team of experts, this highly interdisciplinary book will benefit a broad range of health professionals and researchers working in biochemistry, biotechnology, nutrition, plant science and food chemistry. It offers an indispensable, up-to-date guide for anyone interested in antioxidants and the role of a plant-based diet in disease prevention and control

Antioxidant Status, Diet, Nutrition, and Health

Andreas M. Papas
Antioxidant Status Diet Nutrition and Health Book PDF

Author : Andreas M. Papas
Publisher : CRC Press
Page : 673 pages
File Size : 43,8 Mb
Release : 2019-10-16
Category : Medical
ISBN : 9781000714807

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Antioxidant Status, Diet, Nutrition, and Health by Andreas M. Papas Pdf

This is the first book to integrate the biological, nutritional, and health aspects of antioxidant status. Fifty contributors integrate and transfer the knowledge of free radicals and antioxidants from the test tube to the laboratory of the biologist, clinical nutritionist, and medical researcher, as well as to the office of the dietician, nutritionist, and physician. Topics examined include factors affecting and methods for evaluating antioxidant status in humans; effect of diet and physiological stage (infancy, aging, exercise, alcoholism, HIV infection, etc.) on antioxidant status; and the role of antioxidant status in nutrition, health, and disease.