Axonal Transport

Author : Bingwei Lu
Publisher : Springer Science & Business Media
Page : 271 pages
File Size : 54,6 Mb
Release : 2011-05-16
Category : Medical
ISBN : 9789400712911

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Mitochondrial Dynamics and Neurodegeneration by Bingwei Lu Pdf

Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this process are commonly found in neurodegenerative diseases, offering a new paradigm for investigating mechanisms of neurodegeneration. To provide researchers working on neurodegenerative diseases and mitochondria with updated information on this rapidly progressing field, we have invited experts in the field to critically review recent progresses and identify future research directions. The topics include genetics of mitochondrial dynamics, mitochondrial dynamics and bioenergetics, autophagy, apoptosis, and axonal transport, and its role in neurological diseases, including Alzheimer’s, Parkinson’s, and Huntington’s diseases.

Author : John Elam
Publisher : Springer Science & Business Media
Page : 292 pages
File Size : 51,5 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781468411973

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Axonal Transport in Neuronal Growth and Regeneration by John Elam Pdf

Over the past several years, the pace of research on the control of axonal growth has increased at a remarkable rate, and this activity is reflected in a growing literature dealing with various aspects of axonal growth and regener ation. It appears timely to review the role played by axonal transport in the intrinsic responses of neurons in the growth and regrowth processes. Through the cooperation of the senior editors of this series, we have been given the opportunity to bring such a focus to the current volume. We wish to acknowledge that the contributing authors attended a confer ence on "The Role of Axonal Transport in Neuronal Growth and Regenera tion" held in Tallahassee, Florida in March, 1983, sponsored by the Psycho biology Research Center of the Florida State University. It is our hope that many of the perceptions and insights expressed in these chapters resulted from our interactions.

Author : W. Maxwell Cowan,Michel A. Cuénod
Publisher : Elsevier Science & Technology
Page : 392 pages
File Size : 50,7 Mb
Release : 1975
Category : Axonal transport
ISBN : UCAL:B4311533

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The Use of Axonal Transport for Studies of Neuronal Connectivity by W. Maxwell Cowan,Michel A. Cuénod Pdf

Author : D. G. Weiss,A. Gorio
Publisher : Springer Science & Business Media
Page : 206 pages
File Size : 48,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642857140

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Axoplasmic Transport in Physiology and Pathology by D. G. Weiss,A. Gorio Pdf

Cajal and contemporary scientists have laid the basis of the modem concepts of the organization of the nervous system: the cir cuits of the brain are made up of individual neurons which transfer information via specialized structures called synapses. Soma and den drites usually receive the inputs, then the signal is carried all along the axon to the target areas. To fulfIll this task several types of neurons have developed their unique geometry characterized by a large recep tive area (soma and dendrites) and an often very extensive distal branching with the axon terminals. The volume of cytoplasm which constitutes the neuronal periphery is often far larger than the cell body, where the synthetic machinery is located. It is one of the roles ofaxoplasmic transport to supply the periphery with proper material and to sustain the specialized structures necessary for the physiological activity of the neuron. Furthermore, it has become more and more clear that target areas also exert effects on the innervating neurons, and these effects are not only mediated via recurrent fibers. Synapses have been shown to be able to pick up material from the synaptic left which is then intra axon ally transported back to the cell body. This retrograde axoplasmic transport has therefore been recognized as another basic mechanism to convey signals from the periphery to the centre.

Author : Mark A. Bisby,International Union of Physiological Sciences. Congress
Publisher : New York : Liss
Page : 536 pages
File Size : 45,7 Mb
Release : 1987
Category : Medical
ISBN : UOM:39015011644245

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Axonal Transport by Mark A. Bisby,International Union of Physiological Sciences. Congress Pdf

Author : Sidney Ochs
Publisher : John Wiley & Sons
Page : 488 pages
File Size : 49,8 Mb
Release : 1982
Category : Axonal transport
ISBN : UCAL:B4529242

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Axoplasmic Transport and Its Relation to Other Nerve Functions by Sidney Ochs Pdf

Author : Zafar Iqbal
Publisher : CRC Press
Page : 366 pages
File Size : 41,5 Mb
Release : 2018-05-04
Category : Science
ISBN : 9781351086905

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Axoplasmic Transport by Zafar Iqbal Pdf

Axoplasmic transport is the intracellular movement of cellular components required for the maintenance and normal physiological functioning of neuronal cells. This book provides an up to date reference for both established investigators as well as for those entering in the field.This volume describes the history and methods of the study of transport and the involvement of energy, ions, calmodulin, microtubules and other cellular components in transport. It also discusses the transport of polypeptides, lipids, nucleic acids, neutrotransmitter containing components and various other particles in nerve fibres. A significant portion of this book is devoted to axoplasmic transport, regeneration and the relevance of transport in neurotropic functions are described in the alst four chapters, followed by a discussion on the mechanism of axoplasmic transport.

Author : Anonim
Publisher : Academic Press
Page : 534 pages
File Size : 52,8 Mb
Release : 2016-01-12
Category : Science
ISBN : 9780128033548

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The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon by Anonim Pdf

The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon, a new volume in the Methods in Cell Biology series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in neuronal cells, and includes sections on such topics as actin transport in axons and neurofilament transport. Covers an increasingly appreciated field in cell biology Includes both established and new technologies Contributed by experts in the field

Author : Alessio Vagnoni
Publisher : Humana
Page : 573 pages
File Size : 43,8 Mb
Release : 2022-08-11
Category : Science
ISBN : 1071619896

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Axonal Transport by Alessio Vagnoni Pdf

This volume covers a wide range of model systems from invertebrate to humans and in vitro and in vivo. Chapters detail methods on squid, aplysia, xenopus, mouse in vivo, ex vivo, rodent primary neurons, human-derived neurons, zebrafish, drosophila in vivo, primary neurons, c. elegans, and in vitro reconstitution assays.Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Axonal Transport: Methods and Protocols aims to further our understanding of the trafficking of cellular components in the nervous system leading to the advancement of basic knowledge that underlines the cell biology of the neuron. The chapters “ Live imaging of RNA Transport and Translation in Xenopus Retinal Axons, Retrograde Axonal Transport of Neurotrophins in Basal Forebrain Cholinergic Neurons, Assessment of Mitochondrial Trafficking as A Surrogate of Fast Axonal Transport in Human Induced Pluripotent Stem Cell Derived Spinal Motor Neurons, Drosophila Primary Neuronal Cultures as a Useful Cellular Model to Study and Image Axonal Transport, and In vitro Reconstitution of Kinesin-Based, Axonal mRNA Transport” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com

Author : John Elam
Publisher : Unknown
Page : 304 pages
File Size : 49,7 Mb
Release : 2014-01-15
Category : Electronic
ISBN : 1468411985

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Axonal Transport in Neuronal Growth and Regeneration by John Elam Pdf

Author : Richard S. Smith,Mark A. Bisby
Publisher : John Wiley & Sons
Page : 506 pages
File Size : 47,6 Mb
Release : 1987-01-01
Category : Electronic
ISBN : 0471629928

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Axonal Transport by Richard S. Smith,Mark A. Bisby Pdf

Author : International Union of Physiological Sciences Congress Staff
Publisher : Unknown
Page : 520 pages
File Size : 44,9 Mb
Release : 2024-07-02
Category : Electronic
ISBN : 0783728042

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Axonal Transport by International Union of Physiological Sciences Congress Staff Pdf

Author : Daniel Laskowitz,Gerald Grant
Publisher : CRC Press
Page : 412 pages
File Size : 49,7 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781498766579

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Translational Research in Traumatic Brain Injury by Daniel Laskowitz,Gerald Grant Pdf

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 54,6 Mb
Release : 1987
Category : Electronic
ISBN : OCLC:246538043

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Axonal Transport by Anonim Pdf

Author : Akihiko Takashima,Benjamin Wolozin,Luc Buee
Publisher : Springer Nature
Page : 416 pages
File Size : 51,7 Mb
Release : 2020-02-24
Category : Medical
ISBN : 9789813293588

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Tau Biology by Akihiko Takashima,Benjamin Wolozin,Luc Buee Pdf

This book presents essential studies and cutting-edge research results on tau, which is attracting increasing interest as a target for the treatment of Alzheimer's disease. Tau is well known as a microtubule-associated protein that is predominantly localized in the axons of neurons. In various forms of brain disease, neuronal loss occurs, with deposition of hyperphosphorylated tau in the remaining neurons. Important questions remain regarding the way in which tau forms hyperphosphorylated and fibrillar deposits in neurons, and whether tau aggregation represents the toxic pathway leading to neuronal death. With the help of new technologies, researchers are now solving these long-standing questions. In this book, readers will find the latest expert knowledge on all aspects of tau biology, including the structure and role of the tau molecule, tau localization and function, the pathology, drivers, and markers of tauopathies, tau aggregation, and treatments targeting tau. Tau Biology will be an invaluable source of information and fresh ideas for those involved in the development of more effective therapies and for all who seek a better understanding of the biology of the aging brain.