Biomolecular Free Radical Toxicity

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Biomolecular Free Radical Toxicity

Helen Wiseman,Peter Goldfarb,Tim Ridgway,Alan Wiseman
Biomolecular Free Radical Toxicity Book PDF

Author : Helen Wiseman,Peter Goldfarb,Tim Ridgway,Alan Wiseman
Publisher : Wiley
Page : 0 pages
File Size : 51,5 Mb
Release : 2000-11-17
Category : Science
ISBN : 0471490768

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Biomolecular Free Radical Toxicity by Helen Wiseman,Peter Goldfarb,Tim Ridgway,Alan Wiseman Pdf

Biomolecular Free Radical Toxicity: Causes and Prevention provides a comprehensive overview of biomolecular injury. By discussing recent research and providing interpretations of the available data, this unique and timely book explores the causes of biomolecular injury and the possible routes to its prevention. Split into three sections, the book covers: * macromolecular mechanisms of injury and the role of antioxidants; * gene expression and cell mediated mechanisms of toxicity expression; and, * human and environmental health effects. Written by experts in the field, Biomolecular Free Radical Toxicity: Causes and Prevention will be invaluable to researchers specialising in food and nutrition-based toxicology, biomolecular sciences, biochemistry, genetics, environmental biomonitoring, drug metabolism and carcinogenesis.

Handbook of Antioxidant Methodology

Paul D. Prenzler,Danielle Ryan,Kevin Robards
Handbook of Antioxidant Methodology Book PDF

Author : Paul D. Prenzler,Danielle Ryan,Kevin Robards
Publisher : Royal Society of Chemistry
Page : 537 pages
File Size : 52,5 Mb
Release : 2021-10-20
Category : Medical
ISBN : 9781839161551

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Handbook of Antioxidant Methodology by Paul D. Prenzler,Danielle Ryan,Kevin Robards Pdf

Addressing a number of the controversies on antioxidant testing methods, this book provides guidance on what methods are most appropriate for different situations, how results are interpreted and what can be inferred from the data.

Free Radical Biology and Environmental Toxicity

Kavindra Kumar Kesari,Niraj Kumar Jha
Free Radical Biology and Environmental Toxicity Book PDF

Author : Kavindra Kumar Kesari,Niraj Kumar Jha
Publisher : Springer Nature
Page : 392 pages
File Size : 48,6 Mb
Release : 2022-03-11
Category : Medical
ISBN : 9783030834463

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Free Radical Biology and Environmental Toxicity by Kavindra Kumar Kesari,Niraj Kumar Jha Pdf

The main aim of this book is to collect a series of research articles and reviews from a diverse group of scientists to share their research work on the role of free radical research and environmental toxicity. This book presents various state-of-the-art chapters of recent progress in the field of cellular toxicology and clinical manifestations of various disorders. Topics include cell signaling, various risk factors, the pathophysiology of disease instigation and distribution, mechanistic insights into metal and nanoparticle toxicity, neural toxicity, nongenotoxic carcinogenicity, immune and idiosyncratic toxicity, prevention, biomarkers related to disease progression and therapeutic strategies. In particular, this book provides valuable insight for researchers, pathologists, and clinicians with an interest in toxicological research and cellular impairments with special emphasis on therapeutic advancement.

Phytochemicals

Toshiki Asao,Md Asaduzzaman
Phytochemicals Book PDF

Author : Toshiki Asao,Md Asaduzzaman
Publisher : BoD – Books on Demand
Page : 220 pages
File Size : 54,9 Mb
Release : 2018-11-07
Category : Science
ISBN : 9781789843774

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Phytochemicals by Toshiki Asao,Md Asaduzzaman Pdf

Phytochemicals provides original research work and reviews on the sources of phytochemicals, and their roles in disease prevention, supplementation, and accumulation in fruits and vegetables. The roles of anthocyanin, flavonoids, carotenoids, and taxol are presented in separate chapters. Antioxidative and free radicle scavenging activity of phytochemicals is also discussed. The medicinal properties of Opuntia, soybean, sea buckthorn, and gooseberry are presented in a number of chapters. Supplementation of plant extract with phytochemical properties in broiler meals is discussed in one chapter. The final two chapters include the impact of agricultural practices and novel processing technologies on the accumulation of phytochemicals in fruits and vegetables. This book mainly focuses on medicinal plants and the disease-preventing properties of phytochemicals, which will be a useful resource to the reader.

Systems Biology of Free Radicals and Antioxidants

Ismail Laher
Systems Biology of Free Radicals and Antioxidants Book PDF

Author : Ismail Laher
Publisher : Springer
Page : 0 pages
File Size : 54,9 Mb
Release : 2014-06-16
Category : Medical
ISBN : 3642300170

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Systems Biology of Free Radicals and Antioxidants by Ismail Laher Pdf

The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings.

Free Radicals in Human Health and Disease

Vibha Rani,Umesh Chand Singh Yadav
Free Radicals in Human Health and Disease Book PDF

Author : Vibha Rani,Umesh Chand Singh Yadav
Publisher : Springer
Page : 427 pages
File Size : 54,5 Mb
Release : 2014-11-14
Category : Science
ISBN : 9788132220350

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Free Radicals in Human Health and Disease by Vibha Rani,Umesh Chand Singh Yadav Pdf

The role of oxidative stress in human disease has become an area of intense interest. Free radicals, a normal product of metabolism, exist in all aerobic cells in balance with biochemical antioxidants. Environmental stress increases the levels of free radicals drastically, thereby disturbing the equilibrium between free radical production and the antioxidant capability causing oxidative stress. Over the years, ROS has been implicated in the pathologies of various diseases like cancer, neurological disorder, cardiovascular diseases rheumatoid arthritis, diabetes etc. This book provides an in depth critical state-of-art reviews from established investigators on free radicals, ROS associated pathogenesis of human diseases, biomarkers of oxidative damage, antioxidants, phytonutrients and other related health concerns of modern society. The present book is aimed at graduate students, researchers in academia, industry and clinicians with the interest in redox biology. Special attention has been devoted to the topic of ROS signalling, oxidative stress induced human pathologies & antioxidative therapies. The book consists of four parts in specified topics based on the current literatures for the better understanding of the readers with respect to their subject-wise interests. The first section of the book provides an overview about the ROS production and their measuring tools and techniques followed by the mechanisms involved in the oxidative stress in the second section. The third section describes the involvement of oxidative stress in different human diseases and the last section focuses on the different strategies to ameliorate oxidative stress induced stress.

Immunopharmacology of Free Radical Species

Anonim
Immunopharmacology of Free Radical Species Book PDF

Author : Anonim
Publisher : Elsevier
Page : 301 pages
File Size : 43,6 Mb
Release : 1995-05-15
Category : Medical
ISBN : 0080534546

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Immunopharmacology of Free Radical Species by Anonim Pdf

Free radicals have been implicated in a entire host of different human disease states, which suggests that although they may not have a pivotal causal role, they are involved in the perpetuation of disease. In recentyears, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems to maintain normal cell function. It is theperturbations of these reactions which pose the most intriguing therapeutic challenges. This volume deals with various basic mechanisms of free radical processes and injury. The emphasis in each case is on potential therapeutic strategies developing fromthis new knowledge.

Free Radicals, Oxidative Stress, and Antioxidants

Tomris Özben
Free Radicals Oxidative Stress and Antioxidants Book PDF

Author : Tomris Özben
Publisher : Springer Science & Business Media
Page : 390 pages
File Size : 49,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781475729078

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Free Radicals, Oxidative Stress, and Antioxidants by Tomris Özben Pdf

There has been an explosion of research related to free radicals and antioxidants in recent years, and hundreds of laboratories worldwide are actively involved in many as pects of free radicals, oxidative stress, and antioxidants. The literature on these topics in creases exponentially every year. Over the last few years, we have been fortunate to witness a widespread recognition of the important role of free radicals in a wide variety of pathological conditions including diseases such as atherosclerosis, cardiovascular and neurological diseases, ischemia, emphysema, diabetes, radiation injury, cancer, etc. In ad dition, many laboratories are studying the role of free radicals in the inexorable process of aging. Increased evidence involves free radicals with the etiology of various diseases, thereby suggesting the use of antioxidants as a viable therapeutic approach for the treat ment of free radical mediated pathologies. Despite these impressive developments, many important aspects of free radical and antioxidant research are open for investigation. It is important to understand the overall mechanisms involved in free radical mediated physiological and pathological conditions. This knowledge will undoubtedly lead to the development of new therapeutic approaches to prevent or control free radical related diseases. This book contains the proceedings of the NATO Advanced Study Institute (ASI) on "Free Radicals, Oxidative Stress, and Antioxidants: Pathological and Physiological Sig nificance," which was held in Antalya, Turkey from May 24-June 4, 1997.

Aging

Victor R Preedy
Aging Book PDF

Author : Victor R Preedy
Publisher : Academic Press
Page : 317 pages
File Size : 41,6 Mb
Release : 2014-03-06
Category : Science
ISBN : 9780124055230

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Aging by Victor R Preedy Pdf

Aging: Oxidative Stress and Dietary Antioxidants bridges the trans-disciplinary divide and covers in a single volume the science of oxidative stress in aging and the potentially therapeutic use of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial, and oxidative stress is a single component of this. Gerontologists, geriatricians, nutritionists, and dieticians are separated by divergent skills and professional disciplines that need to be bridged in order to advance preventative as well as treatment strategies. While gerontologists and geriatricians may study the underlying processes of aging, they are less likely to be conversant in the science of nutrition and dietetics. On the other hand, nutritionists and dietitians are less conversant with the detailed clinical background and science of gerontology. This book addresses this gap and brings each of these disciplines to bear on the processes inherent in the oxidative stress of aging. Nutritionists can apply information related to mitochondrial oxidative stress in one disease to diet-related strategies in another unrelated disease Dietitians can prescribe new foods or diets containing anti-oxidants for conditions resistant to conventional pharmacological treatments Dietitians, after learning about the basic biology of oxidative stress, will be able to suggest new treatments to their multidisciplinary teams Nutritionists and dietitians will gain an understanding of cell signaling and be able to suggest new preventative or therapeutic strategies with anti-oxidant rich foods

Oxidative Stress and Chronic Degenerative Diseases

Jose Antonio Morales-Gonzalez
Oxidative Stress and Chronic Degenerative Diseases Book PDF

Author : Jose Antonio Morales-Gonzalez
Publisher : BoD – Books on Demand
Page : 516 pages
File Size : 45,8 Mb
Release : 2013-05-22
Category : Science
ISBN : 9789535111238

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Oxidative Stress and Chronic Degenerative Diseases by Jose Antonio Morales-Gonzalez Pdf

This work responds to the need to find, in a sole document, the affect of oxidative stress at different levels, as well as treatment with antioxidants to revert and diminish the damage. Oxidative Stress and Chronic Degenerative Diseases - a Role for Antioxidants is written for health professionals by researchers at diverse educative institutions (Mexico, Brazil, USA, Spain, Australia, and Slovenia). I would like to underscore that of the 19 chapters, 14 are by Mexican researchers, which demonstrates the commitment of Mexican institutions to academic life and to the prevention and treatment of chronic degenerative diseases.

Oxidative Stress and Biomaterials

Thomas Dziubla,D Allan Butterfield
Oxidative Stress and Biomaterials Book PDF

Author : Thomas Dziubla,D Allan Butterfield
Publisher : Academic Press
Page : 404 pages
File Size : 43,5 Mb
Release : 2016-05-31
Category : Technology & Engineering
ISBN : 9780128032701

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Oxidative Stress and Biomaterials by Thomas Dziubla,D Allan Butterfield Pdf

Oxidative Stress and Biomaterials provides readers with the latest information on biomaterials and the oxidative stress that can pose an especially troubling challenge to their biocompatibility, especially given the fact that, at the cellular level, the tissue environment is a harsh landscape of precipitating proteins, infiltrating leukocytes, released oxidants, and fluctuations of pH which, even with the slightest shift in stasis, can induce a perpetual state of chronic inflammation. No material is 100% non-inflammatory, non-toxic, non-teratogenic, non-carcinogenic, non-thrombogenic, and non-immunogenic in all biological settings and situations. In this embattled terrain, the most we can hope for from the biomaterials we design is a type of “meso-compatibility, a material which can remain functional and benign for as long as required without succumbing to this cellular onslaught and inducing a local inflammatory reaction. Explores the challenges of designing and using biomaterials in order to minimize oxidative stress, reducing patterns of chronic inflammation and cell death Brings together the two fields of biomaterials and the biology of oxidative stress Provides approaches for the design of biomaterials with improved biocompatibility

Free Radical Reactions in Medicine

Janos Feher,Geza Csomos,Andras Vereckei
Free Radical Reactions in Medicine Book PDF

Author : Janos Feher,Geza Csomos,Andras Vereckei
Publisher : Springer Science & Business Media
Page : 300 pages
File Size : 41,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642831041

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Free Radical Reactions in Medicine by Janos Feher,Geza Csomos,Andras Vereckei Pdf

This book aims to provide a concise review of the medical aspects of free radical reactions. Until now, there have been extensive reviews of the subject in a physiological, pathophysiological and biochemical context. Here, however, the authors concentrate on the biology of free radical reactions as relevant to medical practice, emphasizing that the topic is not just a branch of basic science. Consequently, a short introduction on chemical and biological aspects is followed by a detailed discussion of the role played by free radical reactions in the pathogenesis and development of several human diseases and in therapeutic possibilities. The summary of data from the literature is supplemented by the authors' own experimental results. The presentation will help medical researchers to notice so far unknown connections among several diseases and to make them aware of the existance of the so-called "free radical diseases".

Antioxidants in Human Health and Disease

Tapan Kumar Basu,Norman J. Temple,Manohar L. Garg
Antioxidants in Human Health and Disease Book PDF

Author : Tapan Kumar Basu,Norman J. Temple,Manohar L. Garg
Publisher : Wallingford [England] : CABI Pub.
Page : 490 pages
File Size : 45,7 Mb
Release : 1999
Category : Medical
ISBN : UOM:39015047552933

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Antioxidants in Human Health and Disease by Tapan Kumar Basu,Norman J. Temple,Manohar L. Garg Pdf

Antioxidants and their mechanisms of action; Food factors as antioxidants; Coronary heart disease; Malignant disease; Other diseases; Indicators of oxidative stress; Consumer issues.

Antioxidants in Sport Nutrition

Manfred Lamprecht
Antioxidants in Sport Nutrition Book PDF

Author : Manfred Lamprecht
Publisher : CRC Press
Page : 304 pages
File Size : 52,5 Mb
Release : 2014-09-17
Category : Medical
ISBN : 9781466567573

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Antioxidants in Sport Nutrition by Manfred Lamprecht Pdf

The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.

Melatonin

Cristina Manuela Drăgoi,Alina Crenguţa Nicolae
Melatonin Book PDF

Author : Cristina Manuela Drăgoi,Alina Crenguţa Nicolae
Publisher : BoD – Books on Demand
Page : 211 pages
File Size : 40,5 Mb
Release : 2018-11-21
Category : Medical
ISBN : 9781789845044

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Melatonin by Cristina Manuela Drăgoi,Alina Crenguţa Nicolae Pdf

Melatonin, the pineal neurohormone, is a pleiotropic molecule acting in the center of the integrative molecular mechanisms of the organism, based on interconnections of the regulatory systems: neural, endocrine, immune, and genetic, conveying into the uniqueness of human architecture. This book provides a systematic and updated overview of melatonin biochemical mechanisms of action, pharmacological features, and clinical uses, clutching the subject with complete details of pharmaceutical formulations designed for different routes of administration and different health issues, aiming at optimal melatonin bioavailability when therapeutically delivered. The book addresses a broad range of audiences, from healthcare professionals, medically and pharmaceutically based, to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge of the physiological and pathological implications of melatonin and its metabolites.