Brain Lipids And Disorders In Biological Psychiatry

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Brain Lipids and Disorders in Biological Psychiatry

Author : E.R. Skinner
Publisher : Elsevier
Page : 196 pages
File Size : 44,6 Mb
Release : 2002-02-21
Category : Medical
ISBN : 0444509224

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Brain Lipids and Disorders in Biological Psychiatry by E.R. Skinner Pdf

Leading authorities examine the possible role of brain lipids in the development of conditions such as schizophrenia, depression, Alzheimer's disease and personality disorders and violence. A better understanding of the underlying causes of these debilitating medical disorders is of utmost importance and may contribute towards a means of prevention, amelioration and cure. The book is intended to stimulate further interest and lead to increased research in this important development area.

Handbook of Neurochemistry and Molecular Neurobiology

Author : Abel Lajtha,Guido Tettamanti,Gianfrancesco Goracci
Publisher : Springer Science & Business Media
Page : 747 pages
File Size : 47,7 Mb
Release : 2009-10-27
Category : Medical
ISBN : 9780387303451

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Handbook of Neurochemistry and Molecular Neurobiology by Abel Lajtha,Guido Tettamanti,Gianfrancesco Goracci Pdf

Contents include: 'Biochemistry and molecular biology of neural lipids', 'Advances in lipid analysis/lipidomics', 'Metabolism and enzymology of glycerolipids', 'Lipid metabolism in brain development and aging', 'Cellular and subcellular localization of neural lipids', and much more.

Lipids in Health and Disease

Author : Peter Quinn,Xiaoyuan Wang
Publisher : Springer Science & Business Media
Page : 603 pages
File Size : 41,6 Mb
Release : 2008-08-27
Category : Medical
ISBN : 9781402088315

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Lipids in Health and Disease by Peter Quinn,Xiaoyuan Wang Pdf

Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.

Hot Topics in Neural Membrane Lipidology

Author : Akhlaq A. Farooqui
Publisher : Springer Science & Business Media
Page : 423 pages
File Size : 51,9 Mb
Release : 2009-04-05
Category : Medical
ISBN : 9780387096933

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Hot Topics in Neural Membrane Lipidology by Akhlaq A. Farooqui Pdf

Glycerophospholipid and sphingolipid-derived lipid mediators facilitate the transfer of messages not only from one cell to another but also from one subcellular organelle to another. These molecules are not only components of neural membranes but also storage depots for lipid mediators. Information on the generation and involvement of lipid mediators in neurological disorders is scattered throughout the literature in the form of original papers and reviews. This book will provide readers with a comprehensive description of glycerophospholipid, sphingolipid and cholesterol-derived lipid mediators and their involvement in neurological disorders.

Neuroprogression in Psychiatry

Author : Flávio Kapczinski,Michael Berk,Pedro Vieira da Silva Magalhães
Publisher : Oxford University Press
Page : 272 pages
File Size : 46,8 Mb
Release : 2019-03-05
Category : Medical
ISBN : 9780191090882

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Neuroprogression in Psychiatry by Flávio Kapczinski,Michael Berk,Pedro Vieira da Silva Magalhães Pdf

Recent studies regarding the neuropathology of specific neurological disorders suggest that both neurodevelopmental and neurodegenerative processes may play a role. However, in contrast to the neurodegeneration seen in neurological disorders such as Parkinson's and Alzheimer's disease, the term "neuroprogression" has been used to describe the neurodevelopmental aspect of pathological brain re-wiring that takes place in the context of severe psychiatric disorders, such as schizophrenia or bipolar disorder. Within psychiatry, patients with severe psychopathology, such as those depressed patients who eventually commit suicide, have been shown to present with increased inflammatory markers in the brain. A similar increase in inflammatory markers is also found in patients with bipolar disorders and schizophrenia. Thus, oxidative stress, inflammation, and changes in growth factors are thought to be the pathways of neuroprogression. Neuroprogression in Psychiatry provides a comprehensive summary of the current developments in the emerging field of neuroprogression. With contributions by leading researchers in the field, this book examines the role of neuroprogression across a wide range of specific psychiatric disorders, with chapters included on major depressive disorder, anxiety disorder, post-traumatic stress disorder, substance abuse, schizophrenia, and bipolar disorder.

Handbook of Neurochemistry and Molecular Neurobiology

Author : Naren L. Banik,Swapan K. Ray,Abel Lajtha
Publisher : Springer Science & Business Media
Page : 685 pages
File Size : 51,5 Mb
Release : 2009
Category : Medical
ISBN : 9780387303437

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Handbook of Neurochemistry and Molecular Neurobiology by Naren L. Banik,Swapan K. Ray,Abel Lajtha Pdf

Therapeutic approaches in spinal cord injury.- Cell death and tissue degeneration in traumatic brain injury.- neurotransmitters and electrophysiology in brain injury.- neurotransmitters and electrophysiology in brain injury.- Parkinsonism in the MPTP model.- EAE Demyelination.- EAE Neurodegeneration.- Cataract.- Uveitis.- Optic neuritis.- GBS/peripherial neuropathy, paraproteinemia.- Brain Tumor(Tumor Mechanisma).- Brain Tumor and angiogenesis.- SCIDS.- Phenylketone urea and mental retardation.- Neurofibromatosis.- BBB.- Muscular dystrophy.- Stracher.- Diabetic neuropathy/retinopathy/cataract.- Peroxisomes and adrenoleukodystrophy ALD.- Neuroprotection.- NFkB (Inflammation and spinal cord injury).- spinal cord injury and traumatic brain injury.- free radicals and neuroprotection.- Traumatic brain injury.- white matter degeneration.- Mitochondrial membrane defects.- Encephalomyopathies.- metal induced neurodegenaration.- neurometals in protein misfolding neurodegenerative diseases.- hyperammonemia.- kyneurenines in the brain preclinical and clinical studies, therapeutic condiserations.

Metabolomics: From Fundamentals to Clinical Applications

Author : Alessandra Sussulini
Publisher : Springer
Page : 350 pages
File Size : 48,6 Mb
Release : 2017-01-28
Category : Science
ISBN : 9783319476568

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Metabolomics: From Fundamentals to Clinical Applications by Alessandra Sussulini Pdf

This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics are also presented. For researches already experienced in metabolomics, the book will be useful as an updated definitive reference. For beginners in the field and graduate students, the book will provide detailed information about concepts and experimental aspects in metabolomics, as well as examples and perspectives of applications of this strategy to clinical questions.

Stress Consequences

Author : George Fink
Publisher : Academic Press
Page : 780 pages
File Size : 47,5 Mb
Release : 2010-04-06
Category : Psychology
ISBN : 0123751756

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Stress Consequences by George Fink Pdf

Stress is a universal phenomenon that impacts adversely on most people. This volume provides a readily accessible compendium that focuses on the physical and psychological consequences of stress for individuals and society. Clinical attention focuses on disorders of the stress control system (e.g. Cushing’s Syndrome: Addison’s Disease) and the adverse impact of stress on human physical and mental health. Detailed reviews address disorders such as PTSD, anxiety, major depression, psychoses and related disorders such as combat fatigue and burnout. The work covers interactions between stress and neurodegenerative disorders, such as Alzheimer’s disease and Parkinson’s disease, as well as stress-immune-inflammatory interactions in relation to cancer and autoimmune and viral diseases. Emphasis is also placed on the role of stress in obesity, hypertension, diabetes type II and other features of the metabolic syndrome which has now reached epidemic proportions in the USA and other countries. Chapters offer impressive scope with topics addressing animal studies, disaster, diurnal rhythms, drug effects and treatments, cognition and emotion, physical illness, psychopathology, immunology and inflammation, lab studies and tests, and psychological / biochemical / genetic aspects Richly illustrated in full color with over 200 figures Articles carefully selected by one of the world’s most preeminent stress researchers and contributors represent the most outstanding scholarship in the field, with each chapter providing fully vetted and reliable expert knowledge

Fats that Heal, Fats that Kill

Author : Udo Erasmus
Publisher : Book Publishing Company
Page : 484 pages
File Size : 52,5 Mb
Release : 1993
Category : Health & Fitness
ISBN : 0920470386

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Fats that Heal, Fats that Kill by Udo Erasmus Pdf

In Fats that Heal Fats that Kill, expert Udo Erasmus takes an in-depth look at the oil industry. Read about the politics of health and the way our bodies assimilate oil. Learn about modern healthful oils like flax, evening primrose and hemp.

Emergent Collective Properties, Networks and Information in Biology

Author : J. Ricard
Publisher : Elsevier
Page : 296 pages
File Size : 48,8 Mb
Release : 2006-02-10
Category : Computers
ISBN : 0080462154

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Emergent Collective Properties, Networks and Information in Biology by J. Ricard Pdf

The concept of network as a mathematical description of a set of states, or events, linked according to a certain topology has been developed recently and has led to a novel approach of real world. This approach is no doubt important in the field of biology. In fact biological systems can be considered networks. Thus, for instance, an enzyme-catalysed reaction is a network that links, according to a certain topology, the various states of the protein and of its complexes with the substrates and products of the chemical reaction. Connections between neurons, social relations in animal and human populations are also examples of networks. Hence there is little doubt that the concept of network transgresses the boundaries between traditional scientific disciplines. This book is aimed at discussing in physical terms these exciting new topics on simple protein model lattices, supramolecular protein edifices, multienzyme and gene networks. *Physical and mathematical approach of biological phenomena. *Offers biochemists and biologists the mathematical background required to understand the text. *Associates in the same general formulation, the ideas of communication of a message and organization of a system. *Provides a clear-cut definition and mathematical expression of the concepts of reduction, integration, emergence and complexity that were so far time-honoured and vague

High Calorie Diet and the Human Brain

Author : Akhlaq A. Farooqui
Publisher : Springer
Page : 308 pages
File Size : 50,8 Mb
Release : 2015-03-25
Category : Medical
ISBN : 9783319152547

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High Calorie Diet and the Human Brain by Akhlaq A. Farooqui Pdf

The purpose of this monograph is to present readers with a comprehensive and cutting edge description of neurochemical effects of diet (beneficial and harmful effects) in normal human brain and to discuss how present day diet promotes pathogenesis of stroke, AD, PD, and depression in a manner that is useful not only to students and teachers but also to researchers, dietitians, nutritionists and physicians. A diet in sufficient amount and appropriate macronutrients is essential for optimal health of human body tissues. In brain, over-nutrition, particularly with high-calorie diet, not only alters cellular homeostasis, but also results in changes in the intensity of signal transduction processes in reward centers of the brain resulting in food addiction. Over-nutrition produces detrimental effects on human health in general and brain health in particular because it chronically increases the systemic and brain inflammation and oxidative stress along with induction of insulin resistance and leptin resistance in the brain as well as visceral organs. Onset of chronic inflammation and oxidative stress not only leads to obesity and heart disease, but also promotes type II diabetes and metabolic syndrome, which are risk factors for both acute neural trauma (stroke) and chronic age-related neurodegenerative and neuropsychological disorders, such as Alzheimer disease (AD), Parkinson disease (PD) and depression.

Calcium: A Matter of Life or Death

Author : Anonim
Publisher : Elsevier
Page : 584 pages
File Size : 42,8 Mb
Release : 2007-09-17
Category : Science
ISBN : 0080551939

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Calcium: A Matter of Life or Death by Anonim Pdf

Calcium is a versatile carrier of signals regulating many aspects of cellular activity such as fertilization to create a new life and programmed cell death to end it. Calcium homeostasis is strictly controlled by channels, pumps and exchangers functioning as gates for calcium entry and release. Given that calcium is such a versatile messenger the field of calcium signaling is continuously and rapidly expanding. This book reviews the most recent developments in calcium signaling by leading experts in the field. It is a state-of-the-art summary of our present knowledge in this quickly growing field and provides insight into the impressive progress made in many areas of calcium signaling, while reminding us of how much remains to be learned.

Chromatin Structure and Dynamics

Author : J. Zlatanova,S. H. Leuba
Publisher : Gulf Professional Publishing
Page : 546 pages
File Size : 46,7 Mb
Release : 2004
Category : Medical
ISBN : 0444515941

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Chromatin Structure and Dynamics by J. Zlatanova,S. H. Leuba Pdf

Biological processes that replicate, preserve and use the genetic information encoded in DNA must operate in the context of chromatin, a highly organized complex of DNA and proteins. These proteins do not merely package the DNA in the tiny volume of the nucleus, but impart the structure the ability to change according to the requirements of the specific process the DNA is involved in. Moreover, chromatin structure is used by the cell to control the activity of DNA. In this volume the basics of chromatin structure and dynamics are presented by established experts in the field.

Omega Fatty Acids in Brain and Neurological Health

Author : Ronald Ross Watson,Victor R. Preedy
Publisher : Academic Press
Page : 518 pages
File Size : 42,7 Mb
Release : 2019-06-12
Category : Medical
ISBN : 9780128152393

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Omega Fatty Acids in Brain and Neurological Health by Ronald Ross Watson,Victor R. Preedy Pdf

Research has clearly established a link between omega fatty acids and general health, particularly cardiovascular health. Omega Fatty Acids in Brain and Neurological Health, Second Edition, illustrates the importance of omega-3 fatty acids in longevity, cognitive impairment and structure and function of the brain's neurons and also the adverse effects of omega-6 fatty acids on neurological function. This book encompasses some of the most recent research on the links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep and neurodegenerative diseases. This completely updated second edition focuses on the counterbalancing dietary and tissue omega-6 fatty acids as well as it studies the effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases. Provides a comprehensive introduction to omega-3 and omega-6 fatty acids in neurological health and directions for future research Features novel focus on the adverse effects of omega-6 fatty acids on neurological function and the counterbalancing of dietary and tissue omega-6 Illustrates the importance of omega-3 fatty acids in longevity and cognitive impairment Features new chapters on early effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases Discusses links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements