Cardioprotection

Author : Naseer Ahmed
Publisher : Academic Press
Page : 0 pages
File Size : 55,6 Mb
Release : 2019-05-31
Category : Science
ISBN : 0128180234

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Pathophysiology of Ischemia Reperfusion Injury and Use of Fingolimod in Cardioprotection by Naseer Ahmed Pdf

Pathophysiology of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is a deep examination into the mechanisms of myocardial ischemiareperfusion injury and role of fingolimod as a cardioprotective agent through its antioxidant, anti-apoptotic and anti-inflammatory effects. Dr. Ahmed explore the physiology and pathophysiology of myocardial metabolism under normal and ischemic conditions and focused on pharmacological cardioprotection. They provide a concise, yet rigorous discussion of Ischemia-Reperfusion Injury, Myocardial Ischemia during Circulatory Arrest, Myocardial Reperfusion, Myocardial Protection related to Ischemia-Reperfusion Injury and Role of Fingolimod in Cardioprotection. Pathophysiology of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is ideal for researchers, cardiovascular scientists, and clinical pharmacologists to further work in this challenging area and apply this knowledge to clinical trials for cardioprotection.

Author : Derek Hausenloy,Derek Yellon
Publisher : OUP Oxford
Page : 144 pages
File Size : 41,7 Mb
Release : 2009-08-20
Category : Medical
ISBN : 9780191575488

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Cardioprotection by Derek Hausenloy,Derek Yellon Pdf

Coronary heart disease (CHD) is the leading cause of death worldwide with 3.8 million men and 3.4 million women dying each year. Cardioprotection refers to the prevention of CHD and the clinical improvement in patients suffering from cardiovascular problems. This book focuses on the role of cardioprotection in surgery and the use of pharmacological therapies such as ACE-inhibitors, statins and beta-blockers in order to reduce the myocardial injury sustained by the patient and the significant risk of morbidity and mortality. It includes new cardioprotective strategies aimed at improving the clinical outcomes of patients in these settings, as well as current well-established methods for reducing myocardial injury in acute coronary syndrome patients.

Author : G.F. Baxter,Derek M. Yellon
Publisher : Springer Science & Business Media
Page : 240 pages
File Size : 53,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401153126

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Delayed Preconditioning and Adaptive Cardioprotection by G.F. Baxter,Derek M. Yellon Pdf

Interest in the ability of myocardium to adapt to ischaemic stress has continued to grow since the discovery of ischaemic preconditioning in 1986. In 1993, two reports heralded the recognition of a delayed preconditioning response in the heart, now commonly known as the `second window' of protection. Since then, a number of studies have described the ability of delayed preconditioning and related adaptive phenomena to protect against a variety of pathologies in the ischaemic and reperfused myocardium. Our understanding of the cellular mechanisms of sub-acute adaptive cardioprotection has advanced considerably during this period. This compilation of state-of-the-art reviews by those who have made significant contributions to this field provides detailed and critical analysis of this research, from molecular basis to potential clinical relevance. The book aims to provide an authoritative, comprehensive and thoroughly up-to-date overview for scientists and clinicians engaged in, or observing, this rapidly-developing area of heart research. It will also be of interest to those engaged in research on other tissues where ischaemia-reperfusion pathology is of major concern.

Author : Claudia Penna,Nina Kaludercic,Valentina Mercurio,Nazareno Paolocci
Publisher : Frontiers Media SA
Page : 111 pages
File Size : 42,9 Mb
Release : 2022-10-11
Category : Science
ISBN : 9782832502075

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Cardioprotection, Sex and Gender Differences by Claudia Penna,Nina Kaludercic,Valentina Mercurio,Nazareno Paolocci Pdf

Author : Shinya Minatoguchi
Publisher : Springer Nature
Page : 64 pages
File Size : 55,9 Mb
Release : 2019-11-16
Category : Science
ISBN : 9789811501678

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Cardioprotection Against Acute Myocardial Infarction by Shinya Minatoguchi Pdf

This book will provide readers with a detailed understanding of the ischemic damage to the myocardium after myocardial infarction, as well as essential tools for the treatment of damaged heart after myocardial infarction. It discusses various methods such as pharmacological pre- and post-conditioning, cytokine therapy, and cell therapy especially using Muse cells.The coverage of Muse cell therapy, which includes the latest work done by the author and his collaborators, is a unique feature of the book. Muse cells have self-renewability and have ability to differentiate into cells with the characteristics of all three germ layers from a single cell, while they are non-tumorigenic. It is the first book to feature the Muse cell therapy, which may offer the new promising therapeutic strategy for acute myocardial infarction.

Author : Robert M. Mentzer Jr.,Masafumi Kitakaze,James M. Downey,Masatsugu Hori
Publisher : Springer Science & Business Media
Page : 239 pages
File Size : 49,7 Mb
Release : 2012-09-10
Category : Medical
ISBN : 9781441987365

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Adenosine, Cardioprotection and Its Clinical Application by Robert M. Mentzer Jr.,Masafumi Kitakaze,James M. Downey,Masatsugu Hori Pdf

The immense growth in the number of articles on adenosine cardioprotection in recent years has been related in large part to the hypothesis that adenosine plays a role in ischemic preconditioning. Ischemic preconditioning is the phenomenon in which a brief period of ischemia (and reperfusion) prior to a more prolonged occlusion reduces myocardial infarct size. This form of myocardial protection has received much interest because ischemic preconditioning has been shown to be the most potent means of reducing infarct size in all animal models so far tested. Within the last six years, the principal focus of adenosine cardioprotection research has centered on the role of adenosine receptors. It is currently thought that adenosine protects the ischemic heart primarily via the activation of adenosine A1 receptors located on the cardiac myocytes. Adenosine is used clinically for terminating supraventricular tachycardia, and as a diagnostic tool in coronary imaging, and has been used postoperatively for blood pressure control after heart surgery. There are also recent reports that adenosine may be safely tolerated and a potentially beneficial additive to cardioplegic solutions during open heart surgery in humans. There is even evidence that ischemic preconditioning may occur in humans under various clinical situations. This volume contains chapters from contributors to the first three symposia on 'Adenosine, Cardioprotection, and its Clinical Application'. All aspects of adenosine cardioprotection and ischemic preconditioning, including potential mechanisms and clinical applications, are discussed by experts in these areas. The reader will find this book to be an excellent source of information on these topics, as well as a guide to future experiments.

Author : Naseer Ahmed
Publisher : Academic Press
Page : 140 pages
File Size : 51,8 Mb
Release : 2019-05-30
Category : Science
ISBN : 9780128182536

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Pathophysiology of Ischemia Reperfusion Injury and Use of Fingolimod in Cardioprotection by Naseer Ahmed Pdf

Pathophysiology of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is a deep examination into the mechanisms of myocardial ischemiareperfusion injury and role of fingolimod as a cardioprotective agent through its antioxidant, anti-apoptotic and anti-inflammatory effects. Dr. Ahmed explore the physiology and pathophysiology of myocardial metabolism under normal and ischemic conditions and focused on pharmacological cardioprotection. They provide a concise, yet rigorous discussion of Ischemia-Reperfusion Injury, Myocardial Ischemia during Circulatory Arrest, Myocardial Reperfusion, Myocardial Protection related to Ischemia-Reperfusion Injury and Role of Fingolimod in Cardioprotection. Pathophysiology of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is ideal for researchers, cardiovascular scientists, and clinical pharmacologists to further work in this challenging area and apply this knowledge to clinical trials for cardioprotection. Provides detailed and critical analysis of the latest research in the field from molecular basis to potential clinical relevance Examines the effect of fingolimod/sphingosine 1-phosphate in cardioprotection, pointing to future myocardial preventative strategies

Author : Zhi-Ren Zhang,Yue Li,Jun Pu,Yong Xia,Ming-Ming Wu
Publisher : Frontiers Media SA
Page : 225 pages
File Size : 40,7 Mb
Release : 2022-11-30
Category : Science
ISBN : 9782832508008

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Cardiovascular Toxicity Associated with Cancer Treatment: Strategies for Diagnosis, Management and Cardioprotection by Zhi-Ren Zhang,Yue Li,Jun Pu,Yong Xia,Ming-Ming Wu Pdf

Author : Benzhi Cai,Hua Zhu,Naufal Zagidullin
Publisher : Frontiers Media SA
Page : 727 pages
File Size : 46,9 Mb
Release : 2022-01-19
Category : Science
ISBN : 9782889740901

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Cardio-Protection and Heart Repair: New Drugs, Targets and Approaches by Benzhi Cai,Hua Zhu,Naufal Zagidullin Pdf

Author : Derek Hausenloy,Derek Yellon
Publisher : Oxford University Press
Page : 138 pages
File Size : 50,5 Mb
Release : 2009-08-20
Category : Medical
ISBN : 9780199544769

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Cardioprotection by Derek Hausenloy,Derek Yellon Pdf

Coronary heart disease (CHD) is the leading cause of death worldwide. Cardioprotection refers to the prevention of CHD and the clinical improvement in patients suffering from cardiovascular problems.

Author : James Allen Coles
Publisher : Unknown
Page : 508 pages
File Size : 49,7 Mb
Release : 2002
Category : Coronary heart disease
ISBN : MINN:31951P008897034

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Pharmacological Approaches to Cardioprotection by James Allen Coles Pdf

Author : Stephan Gielen,Guy De Backer,Massimo Piepoli,David Wood
Publisher : European Society of Cardiology
Page : 369 pages
File Size : 41,6 Mb
Release : 2015
Category : Medical
ISBN : 9780199656653

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The ESC Textbook of Preventive Cardiology by Stephan Gielen,Guy De Backer,Massimo Piepoli,David Wood Pdf

"EACPR, European Association for Cardiovascular Prevention and Rehabilitation -- European Society of Cardiology."

Author : Dale Adam Lauver
Publisher : Unknown
Page : 264 pages
File Size : 50,6 Mb
Release : 2007
Category : Electronic
ISBN : UOM:39015070903300

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Novel Interventions for Cardioprotection by Dale Adam Lauver Pdf

Author : Jennifer E. Van Eyk,Michael J. Dunn
Publisher : John Wiley & Sons
Page : 423 pages
File Size : 52,6 Mb
Release : 2006-03-06
Category : Science
ISBN : 9783527605453

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Proteomic and Genomic Analysis of Cardiovascular Disease by Jennifer E. Van Eyk,Michael J. Dunn Pdf

This is the very first book to focus on this new approach that will eventually aid in developing new diagnostic markers and therapies for controlling and treating heart disease - the number-one killer in the industrialized world. Divided into two parts, the book describes not only the potentials, but also the limitations of these technologies. The editors, both well known within the scientific community, provide new insights into the biochemical and cellular mechanisms of cardiovascular disease, as well as covering the transition into clinical applications. In so doing, they highlight the various strategies and technical aspects so as to assist the growing number of researchers intending to utilize these approaches. The result is an excellent way of educating and informing graduate students, post-doctoral fellows as well as researchers in academia and industry about the latest developments in this area.

Author : Anonim
Publisher : Academic Press
Page : 336 pages
File Size : 50,7 Mb
Release : 2010-12-16
Category : Science
ISBN : 0123850622

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Cardiovascular Pharmacology: Endothelial Control by Anonim Pdf

Cardiovascular disease remains a major cause of death and disability in developed countries and, increasingly so, in the developing world. Presented in this volume of Advances in Pharmacology are some of the most promising possibilities for treating large numbers of individuals afflicted with these conditions. Contains up-to-date reviews of the most important emerging cardiovascular therapies written by world leaders in the field