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Author : Benzhi Cai,Hua Zhu,Naufal Zagidullin
Publisher : Frontiers Media SA
Page : 727 pages
File Size : 44,9 Mb
Release : 2022-01-19
Category : Science
ISBN : 9782889740901
Author : James Allen Coles
Publisher : Unknown
Page : 508 pages
File Size : 53,6 Mb
Release : 2002
Category : Coronary heart disease
ISBN : MINN:31951P008897034
Author : Stephan Gielen,Guy De Backer,Massimo Piepoli,David Wood
Publisher : European Society of Cardiology
Page : 369 pages
File Size : 42,7 Mb
Release : 2015
Category : Medical
ISBN : 9780199656653
"EACPR, European Association for Cardiovascular Prevention and Rehabilitation -- European Society of Cardiology."
Author : Paulo J. Oliveira
Publisher : Springer
Page : 708 pages
File Size : 47,7 Mb
Release : 2018-03-21
Category : Medical
ISBN : 9783319733449
This book addresses the therapeutic strategies to target mitochondrial metabolism in diseases where the function of that organelle is compromised, and it discusses the effective strategies used to create mitochondrial-targeted agents that can become commercially available drug delivery platforms. The consistent growth of research focused in understanding the multifaceted role of mitochondria in cellular metabolism, controlling pathways related with cell death, and ionic/redox regulation has extended the research of mitochondrial chemical-biological interactions to include various pharmacological and toxicological applications. Not only does the book extensively cover basic mitochondrial physiology, but it also links the molecular interactions within these pathways to a variety of diseases. It is one of the first books to combine state-of-the-art reviews regarding basic mitochondrial biology, the role of mitochondrial alterations in different diseases, and the importance of that organelle as a target for pharmacological and non-pharmacological interventions to improve human health. The different chapters highlight the chemical-biological linkages of the mitochondria in context with drug development and clinical applications.
Author : Tomas A. Salerno,Marco Ricci
Publisher : John Wiley & Sons
Page : 344 pages
File Size : 42,5 Mb
Release : 2008-04-15
Category : Medical
ISBN : 9781405178433
Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.
Author : Sameer Mehta
Publisher : John Wiley & Sons
Page : 445 pages
File Size : 40,9 Mb
Release : 2017-10-02
Category : Medical
ISBN : 9781119095415
Benefit from this concise yet comprehensive manual, designed to improve the practice and process of STEMI interventions Understand the varied pharmacological options available in managing STEMI patients, including newer anti-coagulants Improve your STEMI procedure technique through expert guidance, including stent choice, and other techniques such as trans radial procedures Provides an overview of STEMI networks internationally and how to set up a STEMI program Reviews future perspectives for STEMI and the role of telemedicine for STEMI procedures
Author : Institute of Medicine,Board on Global Health,Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries
Publisher : National Academies Press
Page : 483 pages
File Size : 42,5 Mb
Release : 2010-06-29
Category : Medical
ISBN : 9780309157612
Cardiovascular disease (CVD), once thought to be confined primarily to industrialized nations, has emerged as a major health threat in developing countries. Cardiovascular disease now accounts for nearly 30 percent of deaths in low and middle income countries each year, and is accompanied by significant economic repercussions. Yet most governments, global health institutions, and development agencies have largely overlooked CVD as they have invested in health in developing countries. Recognizing the gap between the compelling evidence of the global CVD burden and the investment needed to prevent and control CVD, the National Heart, Lung, and Blood Institute (NHLBI) turned to the IOM for advice on how to catalyze change. In this report, the IOM recommends that the NHLBI, development agencies, nongovernmental organizations, and governments work toward two essential goals: creating environments that promote heart healthy lifestyle choices and help reduce the risk of chronic diseases, and building public health infrastructure and health systems with the capacity to implement programs that will effectively detect and reduce risk and manage CVD. To meet these goals, the IOM recommends several steps, including improving cooperation and collaboration; implementing effective and feasible strategies; and informing efforts through research and health surveillance. Without better efforts to promote cardiovascular health, global health as a whole will be undermined.
Author : Xianwei Wang,Min Zhang,Zufeng Ding
Publisher : Frontiers Media SA
Page : 397 pages
File Size : 45,9 Mb
Release : 2022-10-06
Category : Science
ISBN : 9782832501597
Author : José Marín-García
Publisher : Springer Science & Business Media
Page : 568 pages
File Size : 48,8 Mb
Release : 2007-12-07
Category : Medical
ISBN : 9780387740720
In this book, the genetic and molecular basis of cardiovascular aging is examined in detail and a comprehensive assessment given of the bioenergetics changes occurring in human and animal models of cardiac aging. Both current diagnostic and future therapeutic modalities are presented, giving this book a dual-pronged approach. Cardiac aging, like aging in general, is a complex process involving numerous cellular and molecular changes. This book sheds new light on the phenomenon.
Author : Wenyong Tan
Publisher : BoD – Books on Demand
Page : 164 pages
File Size : 53,9 Mb
Release : 2018-11-14
Category : Medical
ISBN : 9781789842371
Cardiotoxicity may be caused by radiotherapy and/or anticancer agents for many malignancies, adverse effects of some drugs in the context of medical intervention or heavy metal intake, especially during the anticancer therapy. This book intends to bring forward the recent development in toxicities from cancer treatment. It updates the possible mechanisms of cardiotoxicities of some anticancer agents and the suggested prevention and treatment strategies. This book contains many valuable contributions from the researchers in oncology and cardiology as well as the clinicians who are experts in this field.
Author : Derek Hausenloy,Derek Yellon
Publisher : OUP Oxford
Page : 144 pages
File Size : 52,9 Mb
Release : 2009-08-20
Category : Medical
ISBN : 9780191575488
Coronary heart disease (CHD) is the leading cause of death worldwide with 3.8 million men and 3.4 million women dying each year. Cardioprotection refers to the prevention of CHD and the clinical improvement in patients suffering from cardiovascular problems. This book focuses on the role of cardioprotection in surgery and the use of pharmacological therapies such as ACE-inhibitors, statins and beta-blockers in order to reduce the myocardial injury sustained by the patient and the significant risk of morbidity and mortality. It includes new cardioprotective strategies aimed at improving the clinical outcomes of patients in these settings, as well as current well-established methods for reducing myocardial injury in acute coronary syndrome patients.
Author : Adriano D. Andricopulo,Leonardo L. G. Ferreira
Publisher : Frontiers Media SA
Page : 415 pages
File Size : 50,6 Mb
Release : 2019-02-05
Category : Electronic
ISBN : 9782889457441
Chemoinformatics is paramount to current drug discovery. Structure- and ligand-based drug design strategies have been used to uncover hidden patterns in large amounts of data, and to disclose the molecular aspects underlying ligand-receptor interactions. This Research Topic aims to share with a broad audience the most recent trends in the use of chemoinformatics in drug design. To that end, experts in all areas of drug discovery have made their knowledge available through a series of articles that report state-of-the-art approaches. Readers are provided with outstanding contributions focusing on a wide variety of topics which will be of great value to those interested in the many different and exciting facets of drug design.
Author : James T. Willerson,David R. Holmes, Jr.
Publisher : Springer
Page : 783 pages
File Size : 44,6 Mb
Release : 2015-03-11
Category : Medical
ISBN : 9781447128281
Cardiovascular Medicine: Coronary Artery Disease will offer today's most up-to-date, user-friendly guidance on the evaluation, diagnosis, and medical and surgical treatment of this most important aspect of cardiovascular disease and will be on the wish list for every trainee and practicising cardiologist, cardiac surgeon, vascular surgeon, diabetologist, cardiac radiologist and any physician who manages cardiac patients. The book is dedicated to providing comprehensive coverage of every aspect of coronary arterial medicine from cardiac signs and symptoms through imaging and the genetic basis for coronary disease to surgery, interventions, treatment and also to preventive cardiology. The Editor – and a group of contributing world authorities – offer their decades of scientific and clinical experience. A major selling point is the consistent chapter organization, clear design, and engaging text that includes user-friendly features such as tables, lists and treatment boxes. The reader will have all the guidance to diagnose and manage a full range of conditions in a series of textbook resources, while also having access to additional video material from the integral website.
Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 43,7 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author : Hai Yu Xu,Chang-xiao Liu,Yanqiong Zhang,Yan Xu,Takashi Sato
Publisher : Frontiers Media SA
Page : 1019 pages
File Size : 47,6 Mb
Release : 2023-09-19
Category : Science
ISBN : 9782832535516
ntegrative Pharmacology can be used to determine the multi-pharmacological effects of traditional medicines such as traditional Chinese medicine (TCM), Kampo, Sa-sang, Ayurveda, etc.). Through qualitative and quantitative pharmacokinetic-pharmacodynamic (PK-PD) correlations among multi-constituents and multi-targets, integrating chemical profiling, ADME/PK processes, molecular network calculation and resulting experimental validation, the use of Integrative Pharmacology has become widespread. The data has provided a novel paradigm to evaluate the druggability of bioactive ingredients of herbs or formulae, to decipher the pharmacological mechanisms of drug action and to screen potentially new indications for approved drugs and previously unidentified adverse events. On this basis, Integrative Pharmacology may offer an effective way to test the potential scientific basis for traditional medicines and to assess what roles of traditional medicine can and cannot play in pharmaceuticals.